Result of FASTA (omim) for
pFN21AE4077
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4077, 403 aa
1>>>pF1KE4077 403 - 403 aa - 403 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1502+/-0.000482; mu= 9.3700+/- 0.030
mean_var=170.1574+/-36.027, 0's: 0 Z-trim(115.3): 209 B-trim: 725 in 1/54
Lambda= 0.098322
statistics sampled from 25386 (25636) to 25386 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.301), width: 16
Scan time: 7.360
The best scores are: opt bits E(85289)
NP_775107 (OMIM: 616148) tripartite motif-containi ( 403) 2717 397.9 2.4e-110
NP_434698 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 724 115.2 3e-25
NP_998755 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 724 115.2 3e-25
NP_005789 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 724 115.2 3e-25
NP_001007279 (OMIM: 605661) E3 ubiquitin-protein l ( 410) 724 115.2 3e-25
NP_001128327 (OMIM: 606123) E3 ubiquitin-protein l ( 343) 290 53.5 9.1e-07
NP_001020111 (OMIM: 606123) E3 ubiquitin-protein l ( 477) 290 53.7 1.1e-06
XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 290 53.7 1.1e-06
NP_057186 (OMIM: 606123) E3 ubiquitin-protein liga ( 477) 290 53.7 1.1e-06
XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 290 53.7 1.1e-06
XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 290 53.7 1.1e-06
XP_016856907 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 283 52.4 1.5e-06
XP_016856908 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 283 52.4 1.5e-06
XP_005249433 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
XP_005249432 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
NP_001229712 (OMIM: 600830) tripartite motif-conta ( 539) 285 53.0 2e-06
XP_006715243 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
XP_005249434 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
NP_003440 (OMIM: 600830) tripartite motif-containi ( 539) 285 53.0 2e-06
XP_005249431 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
XP_005249435 (OMIM: 600830) PREDICTED: tripartite ( 539) 285 53.0 2e-06
NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 278 52.0 3.7e-06
XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 277 51.9 4.6e-06
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 261 49.6 2e-05
NP_912730 (OMIM: 606474) tripartite motif-containi ( 358) 258 49.0 2.2e-05
XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685) 260 49.6 2.8e-05
NP_001180210 (OMIM: 189960,300000,300552) E3 ubiqu ( 228) 252 48.0 2.9e-05
NP_438112 (OMIM: 300204,300928) probable E3 ubiqui ( 705) 260 49.6 2.9e-05
XP_005262119 (OMIM: 300204,300928) PREDICTED: prob ( 715) 260 49.6 2.9e-05
NP_036348 (OMIM: 300204,300928) probable E3 ubiqui ( 735) 260 49.6 3e-05
NP_001180209 (OMIM: 189960,300000,300552) E3 ubiqu ( 451) 252 48.3 4.6e-05
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 252 48.3 4.9e-05
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 252 48.3 4.9e-05
NP_001180207 (OMIM: 189960,300000,300552) E3 ubiqu ( 540) 252 48.3 5.2e-05
XP_016885030 (OMIM: 189960,300000,300552) PREDICTE ( 540) 252 48.3 5.2e-05
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 252 48.3 5.3e-05
NP_150631 (OMIM: 189960,300000,300552) E3 ubiquiti ( 629) 252 48.4 5.8e-05
XP_016885027 (OMIM: 189960,300000,300552) PREDICTE ( 629) 252 48.4 5.8e-05
XP_016885028 (OMIM: 189960,300000,300552) PREDICTE ( 629) 252 48.4 5.8e-05
XP_016885026 (OMIM: 189960,300000,300552) PREDICTE ( 629) 252 48.4 5.8e-05
XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667) 252 48.4 6.1e-05
NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 252 48.4 6.1e-05
NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 252 48.4 6.1e-05
NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 252 48.4 6.1e-05
NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 252 48.4 6.1e-05
XP_016885024 (OMIM: 189960,300000,300552) PREDICTE ( 680) 252 48.4 6.2e-05
XP_016885023 (OMIM: 189960,300000,300552) PREDICTE ( 718) 252 48.5 6.4e-05
XP_011543827 (OMIM: 189960,300000,300552) PREDICTE ( 718) 252 48.5 6.4e-05
XP_011543829 (OMIM: 189960,300000,300552) PREDICTE ( 718) 252 48.5 6.4e-05
XP_006724555 (OMIM: 189960,300000,300552) PREDICTE ( 718) 252 48.5 6.4e-05
>>NP_775107 (OMIM: 616148) tripartite motif-containing p (403 aa)
initn: 2717 init1: 2717 opt: 2717 Z-score: 2102.2 bits: 397.9 E(85289): 2.4e-110
Smith-Waterman score: 2717; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 DKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEIT
310 320 330 340 350 360
370 380 390 400
pF1KE4 LIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH
:::::::::::::::::::::::::::::::::::::::::::
NP_775 LIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH
370 380 390 400
>>NP_434698 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 640 init1: 244 opt: 724 Z-score: 574.3 bits: 115.2 E(85289): 3e-25
Smith-Waterman score: 724; 34.3% identity (70.6% similar) in 306 aa overlap (1-304:1-301)
10 20 30 40 50 60
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
:. .::.:::::: :.:.:::::::::.::..:::.::..: .::: :.:::.::
NP_434 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRP--APFKCPTCR
10 20 30 40 50
70 80 90 100 110
pF1KE4 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH
. : . :::.:: ::..:..:.:::.. . : . .: : ::::..:: : .:.::
NP_434 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ
: : :.: : . ....:: .:.:. ..:.... . : .. :. .: .: ...
NP_434 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT
:.. : ..:..:. ::.:::. .:. . . . : : :.:.... : ..: . ..
NP_434 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK
.... : :. ::..... :......:. ::: . . : .... .: .. ..
NP_434 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 NVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSE
.. .:.
NP_434 KLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFS
300 310 320 330 340 350
>>NP_998755 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 640 init1: 244 opt: 724 Z-score: 574.3 bits: 115.2 E(85289): 3e-25
Smith-Waterman score: 724; 34.3% identity (70.6% similar) in 306 aa overlap (1-304:1-301)
10 20 30 40 50 60
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
:. .::.:::::: :.:.:::::::::.::..:::.::..: .::: :.:::.::
NP_998 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRP--APFKCPTCR
10 20 30 40 50
70 80 90 100 110
pF1KE4 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH
. : . :::.:: ::..:..:.:::.. . : . .: : ::::..:: : .:.::
NP_998 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ
: : :.: : . ....:: .:.:. ..:.... . : .. :. .: .: ...
NP_998 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT
:.. : ..:..:. ::.:::. .:. . . . : : :.:.... : ..: . ..
NP_998 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK
.... : :. ::..... :......:. ::: . . : .... .: .. ..
NP_998 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 NVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSE
.. .:.
NP_998 KLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFS
300 310 320 330 340 350
>>NP_005789 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 640 init1: 244 opt: 724 Z-score: 574.3 bits: 115.2 E(85289): 3e-25
Smith-Waterman score: 724; 34.3% identity (70.6% similar) in 306 aa overlap (1-304:1-301)
10 20 30 40 50 60
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
:. .::.:::::: :.:.:::::::::.::..:::.::..: .::: :.:::.::
NP_005 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRP--APFKCPTCR
10 20 30 40 50
70 80 90 100 110
pF1KE4 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH
. : . :::.:: ::..:..:.:::.. . : . .: : ::::..:: : .:.::
NP_005 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ
: : :.: : . ....:: .:.:. ..:.... . : .. :. .: .: ...
NP_005 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT
:.. : ..:..:. ::.:::. .:. . . . : : :.:.... : ..: . ..
NP_005 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK
.... : :. ::..... :......:. ::: . . : .... .: .. ..
NP_005 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLVDVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 NVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSE
.. .:.
NP_005 KLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFS
300 310 320 330 340 350
>>NP_001007279 (OMIM: 605661) E3 ubiquitin-protein ligas (410 aa)
initn: 640 init1: 244 opt: 724 Z-score: 574.2 bits: 115.2 E(85289): 3e-25
Smith-Waterman score: 724; 34.3% identity (70.6% similar) in 306 aa overlap (1-304:4-304)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCP
:. .::.:::::: :.:.:::::::::.::..:::.::..: .::: :.:::
NP_001 MDVMELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRP--APFKCP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 NCRSITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLV
.::. : . :::.:: ::..:..:.:::.. . : . .: : ::::..:: : .:.
NP_001 TCRK--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 CGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEK
:: : : :.: : . ....:: .:.:. ..:.... . : .. :. .: .: .
NP_001 CGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 MIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELM
.. :.. : ..:..:. ::.:::. .:. . . . : : :.:.... : ..: .
NP_001 LLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ALTISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIG
.. .... : :. ::..... :......:. ::: . . : .... .: ..
NP_001 NIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPP-SNLPASPLMKNFDTSQWEDIKLV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 QIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITF
.. .. .:.
NP_001 DVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLS
300 310 320 330 340 350
>>NP_001128327 (OMIM: 606123) E3 ubiquitin-protein ligas (343 aa)
initn: 180 init1: 158 opt: 290 Z-score: 242.5 bits: 53.5 E(85289): 9.1e-07
Smith-Waterman score: 298; 26.7% identity (53.4% similar) in 292 aa overlap (4-280:10-278)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPL
..:: :: :: . : :: . :.:.::: :.. . . . : . .
NP_001 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVT---CPEHYRQPLNVYCLL
::.:: :..: ..: : : . : :: :: . : ::. .::...:
NP_001 PCPECR---EMSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQK
70 80 90 100 110
120 130 140 150 160
pF1KE4 DKKLVCGHCLTIGQHHGH---PIDD-LQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL
:.. .: : .:. : : .. .:. :: .. . : ::.: : .: .
NP_001 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTG--NL-----QA
120 130 140 150 160
170 180 190 200 210 220
pF1KE4 KEQKSHSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM
.:..: .: . .. .: .. :...: : .... .: :: . : :.
NP_001 REEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRL
170 180 190 200 210
230 240 250 260 270
pF1KE4 KE----IREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPL--PEVQPVEIYP
.: . .: : : ..:.:.: :. ..:... .. .. . ::: : :
NP_001 RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAP-PTRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE4 RVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLIS
:
NP_001 RTVCRVPGQIEVLRGFLGKWAPRARTSDPGSLGDAPLYPLASEATNGGGSTSALPGDGHW
280 290 300 310 320 330
>>NP_001020111 (OMIM: 606123) E3 ubiquitin-protein ligas (477 aa)
initn: 158 init1: 158 opt: 290 Z-score: 240.7 bits: 53.7 E(85289): 1.1e-06
Smith-Waterman score: 298; 26.7% identity (53.4% similar) in 292 aa overlap (4-280:10-278)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPL
..:: :: :: . : :: . :.:.::: :.. . . . : . .
NP_001 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVT---CPEHYRQPLNVYCLL
::.:: :..: ..: : : . : :: :: . : ::. .::...:
NP_001 PCPECR---EMSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQK
70 80 90 100 110
120 130 140 150 160
pF1KE4 DKKLVCGHCLTIGQHHGH---PIDD-LQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL
:.. .: : .:. : : .. .:. :: .. . : ::.: : .: .
NP_001 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTG--NL-----QA
120 130 140 150 160
170 180 190 200 210 220
pF1KE4 KEQKSHSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM
.:..: .: . .. .: .. :...: : .... .: :: . : :.
NP_001 REEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRL
170 180 190 200 210
230 240 250 260 270
pF1KE4 KE----IREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPL--PEVQPVEIYP
.: . .: : : ..:.:.: :. ..:... .. .. . ::: : :
NP_001 RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAP-PTRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE4 RVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLIS
:
NP_001 RTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAY
280 290 300 310 320 330
>>XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquitin-pr (477 aa)
initn: 158 init1: 158 opt: 290 Z-score: 240.7 bits: 53.7 E(85289): 1.1e-06
Smith-Waterman score: 298; 26.7% identity (53.4% similar) in 292 aa overlap (4-280:10-278)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPL
..:: :: :: . : :: . :.:.::: :.. . . . : . .
XP_006 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVT---CPEHYRQPLNVYCLL
::.:: :..: ..: : : . : :: :: . : ::. .::...:
XP_006 PCPECR---EMSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQK
70 80 90 100 110
120 130 140 150 160
pF1KE4 DKKLVCGHCLTIGQHHGH---PIDD-LQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL
:.. .: : .:. : : .. .:. :: .. . : ::.: : .: .
XP_006 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTG--NL-----QA
120 130 140 150 160
170 180 190 200 210 220
pF1KE4 KEQKSHSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM
.:..: .: . .. .: .. :...: : .... .: :: . : :.
XP_006 REEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRL
170 180 190 200 210
230 240 250 260 270
pF1KE4 KE----IREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPL--PEVQPVEIYP
.: . .: : : ..:.:.: :. ..:... .. .. . ::: : :
XP_006 RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAP-PTRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE4 RVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLIS
:
XP_006 RTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAY
280 290 300 310 320 330
>>NP_057186 (OMIM: 606123) E3 ubiquitin-protein ligase T (477 aa)
initn: 158 init1: 158 opt: 290 Z-score: 240.7 bits: 53.7 E(85289): 1.1e-06
Smith-Waterman score: 298; 26.7% identity (53.4% similar) in 292 aa overlap (4-280:10-278)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPL
..:: :: :: . : :: . :.:.::: :.. . . . : . .
NP_057 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVT---CPEHYRQPLNVYCLL
::.:: :..: ..: : : . : :: :: . : ::. .::...:
NP_057 PCPECR---EMSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQK
70 80 90 100 110
120 130 140 150 160
pF1KE4 DKKLVCGHCLTIGQHHGH---PIDD-LQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL
:.. .: : .:. : : .. .:. :: .. . : ::.: : .: .
NP_057 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTG--NL-----QA
120 130 140 150 160
170 180 190 200 210 220
pF1KE4 KEQKSHSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM
.:..: .: . .. .: .. :...: : .... .: :: . : :.
NP_057 REEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRL
170 180 190 200 210
230 240 250 260 270
pF1KE4 KE----IREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPL--PEVQPVEIYP
.: . .: : : ..:.:.: :. ..:... .. .. . ::: : :
NP_057 RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAP-PTRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE4 RVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLIS
:
NP_057 RTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAY
280 290 300 310 320 330
>>XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquitin-pr (477 aa)
initn: 158 init1: 158 opt: 290 Z-score: 240.7 bits: 53.7 E(85289): 1.1e-06
Smith-Waterman score: 298; 26.7% identity (53.4% similar) in 292 aa overlap (4-280:10-278)
10 20 30 40 50
pF1KE4 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPL
..:: :: :: . : :: . :.:.::: :.. . . . : . .
XP_011 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 KCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVT---CPEHYRQPLNVYCLL
::.:: :..: ..: : : . : :: :: . : ::. .::...:
XP_011 PCPECR---EMSPQ--RNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHH-EPLKLFCQK
70 80 90 100 110
120 130 140 150 160
pF1KE4 DKKLVCGHCLTIGQHHGH---PIDD-LQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKL
:.. .: : .:. : : .. .:. :: .. . : ::.: : .: .
XP_011 DQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTG--NL-----QA
120 130 140 150 160
170 180 190 200 210 220
pF1KE4 KEQKSHSEKM--IQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERM
.:..: .: . .. .: .. :...: : .... .: :: . : :.
XP_011 REEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL-------ETEEEETASRL
170 180 190 200 210
230 240 250 260 270
pF1KE4 KE----IREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPL--PEVQPVEIYP
.: . .: : : ..:.:.: :. ..:... .. .. . ::: : :
XP_011 RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAP-PTRP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE4 RVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLIS
:
XP_011 RTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAY
280 290 300 310 320 330
403 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:12:29 2016 done: Sun Nov 6 04:12:30 2016
Total Scan time: 7.360 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]