Result of FASTA (omim) for
pFN21AE4063
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4063, 340 aa
1>>>pF1KE4063 340 - 340 aa - 340 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7448+/-0.000281; mu= 17.2628+/- 0.018
mean_var=128.2253+/-25.876, 0's: 0 Z-trim(122.8): 272 B-trim: 934 in 1/55
Lambda= 0.113263
statistics sampled from 41122 (41481) to 41122 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.486), width: 16
Scan time: 9.620
The best scores are: opt bits E(85289)
NP_775798 (OMIM: 616955) GTP-binding protein REM 2 ( 340) 2289 384.4 1.9e-106
XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding ( 341) 2277 382.5 7.2e-106
XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding ( 372) 2049 345.3 1.3e-94
XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding ( 373) 2037 343.3 4.9e-94
XP_011534820 (OMIM: 616955) PREDICTED: GTP-binding ( 279) 1349 230.7 2.8e-60
NP_004156 (OMIM: 179503) GTP-binding protein RAD [ ( 308) 814 143.4 6.2e-34
NP_001122322 (OMIM: 179503) GTP-binding protein RA ( 308) 814 143.4 6.2e-34
NP_005252 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 768 135.8 1.1e-31
NP_859053 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 768 135.8 1.1e-31
XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding ( 304) 665 119.0 1.3e-26
NP_054731 (OMIM: 610388) GTP-binding protein REM 1 ( 298) 664 118.8 1.5e-26
XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 655 117.4 4.1e-26
XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 655 117.4 4.1e-26
XP_016868804 (OMIM: 600164) PREDICTED: GTP-binding ( 208) 490 90.2 4.2e-18
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 390 73.9 3.8e-13
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 382 72.6 8.9e-13
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 353 67.9 2.4e-11
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 346 66.7 5.4e-11
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 345 66.6 6e-11
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 345 66.6 6e-11
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 333 64.6 2.2e-10
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 333 64.6 2.2e-10
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 333 64.6 2.2e-10
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 333 64.6 2.2e-10
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 333 64.6 2.2e-10
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 331 64.2 2.7e-10
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 328 63.7 3.9e-10
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 328 63.7 3.9e-10
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 328 63.7 3.9e-10
NP_001243749 (OMIM: 609591,615355) GTP-binding pro ( 183) 320 62.4 8.9e-10
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 306 60.2 4.9e-09
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 301 59.3 7.8e-09
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 301 59.3 7.8e-09
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 293 58.0 1.9e-08
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 293 58.0 1.9e-08
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 292 57.8 2.2e-08
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 292 57.8 2.2e-08
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 291 57.6 2.4e-08
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 292 57.9 2.4e-08
NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 287 57.0 3.8e-08
NP_116307 (OMIM: 612664) ras-related and estrogen- ( 199) 287 57.0 3.9e-08
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 286 56.8 4.2e-08
NP_001170785 (OMIM: 600098) ras-related protein R- ( 169) 284 56.5 5e-08
XP_016872852 (OMIM: 600098) PREDICTED: ras-related ( 182) 284 56.5 5.2e-08
XP_016861376 (OMIM: 608435) PREDICTED: ras-related ( 208) 284 56.6 5.7e-08
NP_001078518 (OMIM: 608435) ras-related protein M- ( 208) 284 56.6 5.7e-08
NP_036351 (OMIM: 608435) ras-related protein M-Ras ( 208) 284 56.6 5.7e-08
XP_005247285 (OMIM: 608435) PREDICTED: ras-related ( 208) 284 56.6 5.7e-08
NP_001239019 (OMIM: 608435) ras-related protein M- ( 208) 284 56.6 5.7e-08
XP_011509876 (OMIM: 179551) PREDICTED: ras-related ( 195) 283 56.4 6.1e-08
>>NP_775798 (OMIM: 616955) GTP-binding protein REM 2 [Ho (340 aa)
initn: 2289 init1: 2289 opt: 2289 Z-score: 2032.2 bits: 384.4 E(85289): 1.9e-106
Smith-Waterman score: 2289; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KE4 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 RDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPA
250 260 270 280 290 300
310 320 330 340
pF1KE4 PPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
::::::::::::::::::::::::::::::::::::::::
NP_775 PPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
310 320 330 340
>>XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding pro (341 aa)
initn: 2276 init1: 1294 opt: 2277 Z-score: 2021.6 bits: 382.5 E(85289): 7.2e-106
Smith-Waterman score: 2277; 99.7% identity (99.7% similar) in 341 aa overlap (1-340:1-341)
10 20 30 40 50 60
pF1KE4 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLV
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 GESGVGKSTLAGTFGGLQGDSAHEPENP-EDTYERRIMVDKEEVTLVVYDIWEQGDAGGW
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_005 GESGVGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGW
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 LRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 SLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGP
250 260 270 280 290 300
300 310 320 330 340
pF1KE4 APPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
:::::::::::::::::::::::::::::::::::::::::
XP_005 APPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
310 320 330 340
>>XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding pro (372 aa)
initn: 2049 init1: 2049 opt: 2049 Z-score: 1819.8 bits: 345.3 E(85289): 1.3e-94
Smith-Waterman score: 2049; 100.0% identity (100.0% similar) in 306 aa overlap (35-340:67-372)
10 20 30 40 50 60
pF1KE4 LDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPR
::::::::::::::::::::::::::::::
XP_016 ILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPR
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE4 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE4 VGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHC
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE4 LQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEG
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE4 RHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPAR
280 290 300 310 320 330
310 320 330 340
pF1KE4 RESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
::::::::::::::::::::::::::::::::::::
XP_016 RESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
340 350 360 370
>>XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding pro (373 aa)
initn: 1294 init1: 1294 opt: 2037 Z-score: 1809.2 bits: 343.3 E(85289): 4.9e-94
Smith-Waterman score: 2037; 99.7% identity (99.7% similar) in 307 aa overlap (35-340:67-373)
10 20 30 40 50 60
pF1KE4 LDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPR
::::::::::::::::::::::::::::::
XP_016 ILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPR
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE4 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE4 VGKSTLAGTFGGLQGDSAHEPENP-EDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDH
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 VGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDH
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE4 CLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEE
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE4 GRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPA
280 290 300 310 320 330
310 320 330 340
pF1KE4 RRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
:::::::::::::::::::::::::::::::::::::
XP_016 RRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
340 350 360 370
>>XP_011534820 (OMIM: 616955) PREDICTED: GTP-binding pro (279 aa)
initn: 782 init1: 756 opt: 1349 Z-score: 1203.1 bits: 230.7 E(85289): 2.8e-60
Smith-Waterman score: 1349; 99.5% identity (99.5% similar) in 205 aa overlap (35-238:67-271)
10 20 30 40 50 60
pF1KE4 LDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPR
::::::::::::::::::::::::::::::
XP_011 ILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPR
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE4 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESG
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE4 VGKSTLAGTFGGLQGDSAHEPENP-EDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDH
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 VGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDH
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE4 CLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSRERAATW
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE4 GRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPA
XP_011 PGR
>>NP_004156 (OMIM: 179503) GTP-binding protein RAD [Homo (308 aa)
initn: 798 init1: 440 opt: 814 Z-score: 730.2 bits: 143.4 E(85289): 6.2e-34
Smith-Waterman score: 822; 49.0% identity (68.6% similar) in 306 aa overlap (50-340:21-308)
20 30 40 50 60 70
pF1KE4 PSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
: :.. : .:. : .: :::: .
NP_004 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
10 20 30 40 50
80 90 100 110 120
pF1KE4 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
NP_004 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 KSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQ
::.:: :::. ... : : ::.: :.:: ::..:.::::::: :.: :: ::.
NP_004 KSALARIFGGV--EDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHCMA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 TGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRH
:::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..:::
NP_004 MGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 LAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRE
: ...:: ::::::::::.. ::::.:::::::: ..:...: : :::
NP_004 CAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRRRE
230 240 250 260 270
310 320 330 340
pF1KE4 SLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
:: :::::::. .: ::.. :. .:.::::::::
NP_004 SLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
280 290 300
>>NP_001122322 (OMIM: 179503) GTP-binding protein RAD [H (308 aa)
initn: 798 init1: 440 opt: 814 Z-score: 730.2 bits: 143.4 E(85289): 6.2e-34
Smith-Waterman score: 822; 49.0% identity (68.6% similar) in 306 aa overlap (50-340:21-308)
20 30 40 50 60 70
pF1KE4 PSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKH----
: :.. : .:. : .: :::: .
NP_001 MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAA
10 20 30 40 50
80 90 100 110 120
pF1KE4 ----QLRRAQAVD-----ELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVG
: : : .:::: . : :::.:: . . ....::.:.: :::
NP_001 LTPGALTAAAAGTGTQGPRLDWPED-----SEDSLSSG--GSDSDESVYKVLLLGAPGVG
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 KSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQ
::.:: :::. ... : : ::.: :.:: ::..:.::::::: :.: :: ::.
NP_001 KSALARIFGGV--EDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQ-DGGRWLPGHCMA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 TGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRH
:::..::.::::. :: :. : ..:: .: :.:.:::::::::.::::::..:::
NP_001 MGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 LAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRE
: ...:: ::::::::::.. ::::.:::::::: ..:...: : :::
NP_001 CAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQ--------AGTRRRE
230 240 250 260 270
310 320 330 340
pF1KE4 SLTKKAKRFLANLVPRNAK--FFKQRSRSCHDLSVL
:: :::::::. .: ::.. :. .:.::::::::
NP_001 SLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
280 290 300
>>NP_005252 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 724 init1: 545 opt: 768 Z-score: 689.7 bits: 135.8 E(85289): 1.1e-31
Smith-Waterman score: 768; 45.5% identity (71.3% similar) in 286 aa overlap (58-340:23-296)
30 40 50 60 70 80
pF1KE4 PPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELD
: :. :. . :.... : ... :
NP_005 MTLNNVTMRQGTVGMQPQQQRWSIPADGRHLMVQKEPHQYSHRNRHSATPED
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 WPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPEN
.. :: :.::. :.:.. . ..:.:.::.::::::::. :.:.. . . :
NP_005 HCRRSWSSDSTDSVISSESG----NTYYRVVLIGEQGVGKSTLANIFAGVHDSMDSDCEV
60 70 80 90 100
150 160 170 180 190 200
pF1KE4 -PEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKV
:::::: .::: : .:... :.::. . ::.:::.:.:::.:::.:.::: :: :.
NP_005 LGEDTYERTLMVDGESATIILLDMWENKGENEWLHDHCMQVGDAYLIVYSITDRASFEKA
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE4 PETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNT
: ..:: .: .:.:.:::::::::.: ::::. ::: : ...:: ::::::..::.
NP_005 SELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSAAVQHNV
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE4 RELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAK-
.::::: :::.:::: .. . .: : :.::. .::.:: ...: .: :
NP_005 KELFEGIVRQVRLRRDSKEKNERRL--------AYQKRKESMPRKARRFWGKIVAKNNKN
230 240 250 260 270 280
330 340
pF1KE4 -FFKQRSRSCHDLSVL
:: .:.::::::::
NP_005 MAFKLKSKSCHDLSVL
290
>>NP_859053 (OMIM: 600164) GTP-binding protein GEM [Homo (296 aa)
initn: 724 init1: 545 opt: 768 Z-score: 689.7 bits: 135.8 E(85289): 1.1e-31
Smith-Waterman score: 768; 45.5% identity (71.3% similar) in 286 aa overlap (58-340:23-296)
30 40 50 60 70 80
pF1KE4 PPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELD
: :. :. . :.... : ... :
NP_859 MTLNNVTMRQGTVGMQPQQQRWSIPADGRHLMVQKEPHQYSHRNRHSATPED
10 20 30 40 50
90 100 110 120 130 140
pF1KE4 WPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPEN
.. :: :.::. :.:.. . ..:.:.::.::::::::. :.:.. . . :
NP_859 HCRRSWSSDSTDSVISSESG----NTYYRVVLIGEQGVGKSTLANIFAGVHDSMDSDCEV
60 70 80 90 100
150 160 170 180 190 200
pF1KE4 -PEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKV
:::::: .::: : .:... :.::. . ::.:::.:.:::.:::.:.::: :: :.
NP_859 LGEDTYERTLMVDGESATIILLDMWENKGENEWLHDHCMQVGDAYLIVYSITDRASFEKA
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE4 PETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNT
: ..:: .: .:.:.:::::::::.: ::::. ::: : ...:: ::::::..::.
NP_859 SELRIQLRRARQTEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSAAVQHNV
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE4 RELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAK-
.::::: :::.:::: .. . .: : :.::. .::.:: ...: .: :
NP_859 KELFEGIVRQVRLRRDSKEKNERRL--------AYQKRKESMPRKARRFWGKIVAKNNKN
230 240 250 260 270 280
330 340
pF1KE4 -FFKQRSRSCHDLSVL
:: .:.::::::::
NP_859 MAFKLKSKSCHDLSVL
290
>>XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding pro (304 aa)
initn: 632 init1: 379 opt: 665 Z-score: 598.6 bits: 119.0 E(85289): 1.3e-26
Smith-Waterman score: 705; 42.2% identity (63.3% similar) in 341 aa overlap (9-340:1-304)
10 20 30 40 50
pF1KE4 MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADAT-LLKKSEKLLAELDRSGLPSA
: ..:: : : :::: : .:.. :. . .. : : ..
XP_011 MTLNTEQEAKTPL-HRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSAS
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 PGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVML
. : .. : :.: : :: :: :::: :: :: ...:.:
XP_011 LNPPTQKPS-PAP-----------D--DW-----SSESSDSEGSWEA-------LYRVVL
60 70 80
120 130 140 150 160 170
pF1KE4 VGESGVGKSTLAGTFGGLQGDSAHE-----PENPEDTYERRIMVDKEEVTLVVYDIWEQG
.:. ::::..::. :.: : . :: : ::.::: . :: :..:::: : ::
XP_011 LGDPGVGKTSLASLFAGKQERDLHEQLGALPSVAEDVYERTLTVDGEDTTLVVVDTWEAE
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 DAG-GWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDL
.: .. ::: :.:..::.:..:: :: .. : ..:: . .:.::::::.::
XP_011 KLDKSWSQESCLQGGSAYVIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADL
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 ARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDP
:: ::::.:::: : ...:: :::::.:.::. :::::.:::.:::: :. :. .:
XP_011 ARCREVSVEEGRACAVVFDCKFIETSATLQHNVAELFEGVVRQLRLRR-RDSAA---KEP
210 220 230 240 250 260
300 310 320 330 340
pF1KE4 GSPEGPAPPARRESLTKKAKRFLANLVPRNAKF--FKQRSRSCHDLSVL
.:. :: ::...:.:::: :. :.:. .: ::.:::.:.::
XP_011 PAPRRPA------SLAQRARRFLARLTARSARRRALKARSKSCHNLAVL
270 280 290 300
340 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:05:51 2016 done: Sun Nov 6 04:05:52 2016
Total Scan time: 9.620 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]