FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4047, 273 aa
  1>>>pF1KE4047 273 - 273 aa - 273 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4813+/-0.000706; mu= 14.1016+/- 0.042
 mean_var=68.2306+/-13.455, 0's: 0 Z-trim(109.7): 36  B-trim: 3 in 1/50
 Lambda= 0.155269
 statistics sampled from 11048 (11079) to 11048 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.34), width:  16
 Scan time:  2.460

The best scores are:                                      opt bits E(32554)
CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3          ( 273) 1871 427.6 4.5e-120
CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1           ( 273) 1458 335.1 3.2e-92
CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12         ( 263)  903 210.8 8.2e-55
CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3       ( 286)  516 124.1 1.1e-28


>>CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3               (273 aa)
 initn: 1871 init1: 1871 opt: 1871  Z-score: 2269.2  bits: 427.6 E(32554): 4.5e-120
Smith-Waterman score: 1871; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)

               10        20        30        40        50        60
pF1KE4 MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL
              190       200       210       220       230       240

              250       260       270   
pF1KE4 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
       :::::::::::::::::::::::::::::::::
CCDS31 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
              250       260       270   

>>CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1                (273 aa)
 initn: 1458 init1: 1458 opt: 1458  Z-score: 1769.2  bits: 335.1 E(32554): 3.2e-92
Smith-Waterman score: 1458; 74.7% identity (90.5% similar) in 273 aa overlap (1-273:1-273)

               10        20        30        40        50        60
pF1KE4 MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED
       ::::..:..:.:..:.:. :: :.::.: .  .:.::: ::::: ..  ::: :.:: .:
CCDS10 MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA
       ::::::::.::.: :::::::::::.::::::..::::.:::.:  ::::::::::::::
CCDS10 RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV
        :::::::::.:::.. :::::::::.::::::::::. .::::: :::.: .:::.::.
CCDS10 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL
       ::::.:::::::::::.::::::::::::::::::::::::. :::.:::::::::::::
CCDS10 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
              190       200       210       220       230       240

              250       260       270   
pF1KE4 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
       ::::.: ::::.:: .: .:::: ::: :: ::
CCDS10 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
              250       260       270   

>>CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12              (263 aa)
 initn: 519 init1: 431 opt: 903  Z-score: 1097.6  bits: 210.8 E(32554): 8.2e-55
Smith-Waterman score: 903; 56.6% identity (77.7% similar) in 242 aa overlap (34-273:26-263)

            10        20        30        40        50        60   
pF1KE4 KLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSL
                                     :  :..::. :   :..: ::.:::.: : 
CCDS85      MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSE
                    10        20        30        40        50     

            70        80        90       100       110       120   
pF1KE4 NVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAP
       :. ::.   : :.:.:::::::: ::: :..::::::.:.:: .::::::::::::: ::
CCDS85 NIEVKEGG-LYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAP
          60         70        80        90       100       110    

           130       140       150       160         170       180 
pF1KE4 LHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVA-YPAFLGPD-EAFALPDSLLVVL
       :..  :.::.::..::::::.::..:::..:. ::.  :::  : . : . .:. :::::
CCDS85 LQTDHYAALLGSNSESWGWDIGRGKLYHQSKG-PGAPQYPA--GTQGEQLEVPERLLVVL
          120       130       140        150         160       170 

             190       200       210       220       230       240 
pF1KE4 DMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLC
       ::.::::.. . : ::: :::::::. :::.::::::.:.: .::..    ::  :. : 
CCDS85 DMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLS
             180       190       200       210       220       230 

             250       260       270   
pF1KE4 RRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
       :  .:  ::  :: ..:.:::: ..: :: ::
CCDS85 RLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
             240       250       260   

>>CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3            (286 aa)
 initn: 472 init1: 164 opt: 516  Z-score: 628.5  bits: 124.1 E(32554): 1.1e-28
Smith-Waterman score: 516; 43.0% identity (71.0% similar) in 193 aa overlap (36-227:93-280)

          10        20        30        40        50         60    
pF1KE4 SGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQ-LRHAWNPEDRSLN
                                     : : : ..:.    .. ..::.. .: : :
CCDS46 CKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRN
             70        80        90       100       110       120  

           70        80        90       100       110       120    
pF1KE4 VFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPL
       :..: .  .:.::.:.:::::: : :.: ..: :::.. : .   :: ::.:.:: :::.
CCDS46 VYIKKNG-FTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEG-PLGTVAVIGIATKRAPM
             130       140       150       160        170       180

          130       140       150       160       170       180    
pF1KE4 HSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMD
       .  ::.::.::: .::::.:  . : :.:. . : ..:   .  . . . . . :.:::.
CCDS46 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVN-G-SFPQCNNAPK-YQIGERIRVILDME
              190       200       210         220        230       

          190       200       210       220       230       240    
pF1KE4 EGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRS
       . ::.:    ..::::::::    :::.::::.:. :::. :.                 
CCDS46 DKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG           
       240       250       260       270       280                 

          250       260       270   
pF1KE4 IRSALGRQRLQDISSLPLPQSLKNYLQYQ




273 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 04:16:42 2016 done: Sun Nov  6 04:16:43 2016
 Total Scan time:  2.460 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]