Result of FASTA (ccds) for
pFN21AE4027
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4027, 236 aa
1>>>pF1KE4027 236 - 236 aa - 236 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0238+/-0.000883; mu= 12.0605+/- 0.053
mean_var=110.0584+/-23.262, 0's: 0 Z-trim(109.5): 68 B-trim: 0 in 0/51
Lambda= 0.122254
statistics sampled from 10904 (10966) to 10904 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.337), width: 16
Scan time: 2.230
The best scores are: opt bits E(32554)
CCDS12863.1 BIRC8 gene_id:112401|Hs108|chr19 ( 236) 1619 295.8 1.7e-80
CCDS14606.1 XIAP gene_id:331|Hs108|chrX ( 497) 1358 250.0 2.1e-66
CCDS8315.1 BIRC3 gene_id:330|Hs108|chr11 ( 604) 320 67.0 3.1e-11
CCDS13512.1 BIRC7 gene_id:79444|Hs108|chr20 ( 280) 309 64.8 6.7e-11
CCDS13513.1 BIRC7 gene_id:79444|Hs108|chr20 ( 298) 309 64.8 7e-11
>>CCDS12863.1 BIRC8 gene_id:112401|Hs108|chr19 (236 aa)
initn: 1619 init1: 1619 opt: 1619 Z-score: 1558.9 bits: 295.8 E(32554): 1.7e-80
Smith-Waterman score: 1619; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236)
10 20 30 40 50 60
pF1KE4 MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 MGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 RRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS
190 200 210 220 230
>>CCDS14606.1 XIAP gene_id:331|Hs108|chrX (497 aa)
initn: 1358 init1: 1358 opt: 1358 Z-score: 1305.8 bits: 250.0 E(32554): 2.1e-66
Smith-Waterman score: 1358; 80.1% identity (94.9% similar) in 236 aa overlap (1-236:262-497)
10 20 30
pF1KE4 MTGYEARLITFGTWMYSVNKEQLARAGFYA
:. ::::..:::::.:::::::::::::::
CCDS14 GRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYA
240 250 260 270 280 290
40 50 60 70 80 90
pF1KE4 IGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGA
.:. :::.::::::::..:::.:::::::::::::::::::.::.:::::::::.:::
CCDS14 LGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC
300 310 320 330 340 350
100 110 120 130 140 150
pF1KE4 LVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLV
::.::.::::::.::.:::: :::.::::::::.:::.::::::.:: ::::::.:::::
CCDS14 LVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLV
360 370 380 390 400 410
160 170 180 190 200 210
pF1KE4 ADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTC
::::.::::. ..: .:::::.::: :: ::::::::::::::::.::.::.::::::::
CCDS14 ADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTC
420 430 440 450 460 470
220 230
pF1KE4 KQCAEAVDRCPMCSAVIDFKQRVFMS
::::::::.:::: .:: :::..:::
CCDS14 KQCAEAVDKCPMCYTVITFKQKIFMS
480 490
>>CCDS8315.1 BIRC3 gene_id:330|Hs108|chr11 (604 aa)
initn: 646 init1: 295 opt: 320 Z-score: 315.2 bits: 67.0 E(32554): 3.1e-11
Smith-Waterman score: 412; 36.0% identity (65.1% similar) in 189 aa overlap (1-173:252-440)
10 20
pF1KE4 MTGYEARLITFGTWMYSV--NKEQLARAGF
: . ::. :: .: :: : :::: :::
CCDS83 MSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGF
230 240 250 260 270 280
30 40 50 60 70 80
pF1KE4 YAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNI-----HL
: .:. : :.:: : ::: :. .::: :::::.: :.::.. ::.:.: .. ::
CCDS83 YYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHL
290 300 310 320 330 340
90 100 110 120 130
pF1KE4 TRSL---------EGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEE
..: :.: . . :. . . .. .:... :..:::. . ::. ...
CCDS83 LEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQR
350 360 370 380 390 400
140 150 160 170 180 190
pF1KE4 RIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMD
.: ..: ::. .. :: ::..:. . :.: .... ..:
CCDS83 KILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCV
410 420 430 440 450 460
200 210 220 230
pF1KE4 RHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS
CCDS83 IPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVL
470 480 490 500 510 520
>>CCDS13512.1 BIRC7 gene_id:79444|Hs108|chr20 (280 aa)
initn: 488 init1: 280 opt: 309 Z-score: 309.2 bits: 64.8 E(32554): 6.7e-11
Smith-Waterman score: 480; 34.7% identity (57.7% similar) in 239 aa overlap (1-236:84-280)
10 20
pF1KE4 MTGYEARLITFGTWMYS--VNKEQLARAGF
: . : :: .: : . : : :: :::
CCDS13 QILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGF
60 70 80 90 100 110
30 40 50 60 70 80
pF1KE4 YAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRS-L
. :..:::.:: : ::: .:: .::: .::::.:.:..::. ::........ :.: :
CCDS13 FHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQL
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE4 EGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLE
:. : . .: .:. . . .:: : :
CCDS13 LGSW------DP----------WEEP------------EDAAPVAPS-VPASG--YPELP
180 190 200
150 160 170 180 190 200
pF1KE4 VLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHL
. . ...: : :.. : :::::::. ::.:.:: ...::.:::::
CCDS13 T--------PRREVQSESAQEPGARDV--EAQLRRLQEERTCKVCLDRAVSIVFVPCGHL
210 220 230 240 250
210 220 230
pF1KE4 VTCKQCAEAVDRCPMCSAVIDFKQRVFMS
: : .:: ... ::.: : . . :.:.:
CCDS13 V-CAECAPGLQLCPICRAPVRSRVRTFLS
260 270 280
>>CCDS13513.1 BIRC7 gene_id:79444|Hs108|chr20 (298 aa)
initn: 494 init1: 286 opt: 309 Z-score: 308.8 bits: 64.8 E(32554): 7e-11
Smith-Waterman score: 498; 34.3% identity (58.2% similar) in 239 aa overlap (1-236:84-298)
10 20
pF1KE4 MTGYEARLITFGTWMYS--VNKEQLARAGF
: . : :: .: : . : : :: :::
CCDS13 QILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGF
60 70 80 90 100 110
30 40 50 60 70 80
pF1KE4 YAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRS-L
. :..:::.:: : ::: .:: .::: .::::.:.:..::. ::........ :.: :
CCDS13 FHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQL
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE4 EGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLE
:. . : . .. .. : : .... : : :.
CCDS13 LGS--WDPWEEPEDAAPVAPSV-PASGYPELP------TPRREVQSESAQEPGG------
180 190 200 210
150 160 170 180 190 200
pF1KE4 VLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHL
:: . . . :.. : :::::::. ::.:.:: ...::.:::::
CCDS13 ------VSPAEAQRAWWVLEPPGARDV--EAQLRRLQEERTCKVCLDRAVSIVFVPCGHL
220 230 240 250 260 270
210 220 230
pF1KE4 VTCKQCAEAVDRCPMCSAVIDFKQRVFMS
: : .:: ... ::.: : . . :.:.:
CCDS13 V-CAECAPGLQLCPICRAPVRSRVRTFLS
280 290
236 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:41:00 2016 done: Sun Nov 6 03:41:00 2016
Total Scan time: 2.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]