Result of FASTA (omim) for
pFN21AE4025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4025, 232 aa
1>>>pF1KE4025 232 - 232 aa - 232 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8086+/-0.00045; mu= 8.4622+/- 0.028
mean_var=200.8165+/-43.804, 0's: 0 Z-trim(117.1): 166 B-trim: 1258 in 1/49
Lambda= 0.090505
statistics sampled from 28492 (28736) to 28492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.337), width: 16
Scan time: 5.750
The best scores are: opt bits E(85289)
NP_060301 (OMIM: 610432,616260) E3 ubiquitin-prote ( 232) 1618 223.4 2.5e-58
XP_011524347 (OMIM: 610432,616260) PREDICTED: E3 u ( 227) 1457 202.4 5.3e-52
XP_011524349 (OMIM: 610432,616260) PREDICTED: E3 u ( 191) 1189 167.3 1.6e-41
XP_011524348 (OMIM: 610432,616260) PREDICTED: E3 u ( 196) 1189 167.3 1.7e-41
NP_061153 (OMIM: 612451) E3 ubiquitin-protein liga ( 228) 233 42.6 0.00068
>>NP_060301 (OMIM: 610432,616260) E3 ubiquitin-protein l (232 aa)
initn: 1618 init1: 1618 opt: 1618 Z-score: 1168.1 bits: 223.4 E(85289): 2.5e-58
Smith-Waterman score: 1618; 100.0% identity (100.0% similar) in 232 aa overlap (1-232:1-232)
10 20 30 40 50 60
pF1KE4 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 PSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNHSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNHSNTT
190 200 210 220 230
>>XP_011524347 (OMIM: 610432,616260) PREDICTED: E3 ubiqu (227 aa)
initn: 1529 init1: 1457 opt: 1457 Z-score: 1054.6 bits: 202.4 E(85289): 5.3e-52
Smith-Waterman score: 1457; 99.5% identity (99.5% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KE4 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 PSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNHSNTT
::::::::::::::::::::::::: :
XP_011 PSSFSGSLIRHLQVSHTLFYDDFIDNNTKIHLSCCCPRPHFHPQVPQ
190 200 210 220
>>XP_011524349 (OMIM: 610432,616260) PREDICTED: E3 ubiqu (191 aa)
initn: 1189 init1: 1189 opt: 1189 Z-score: 866.3 bits: 167.3 E(85289): 1.6e-41
Smith-Waterman score: 1189; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KE4 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVDNNTKIHLSCCC
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 PSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNHSNTT
XP_011 PRPHFHPQVPQ
190
>>XP_011524348 (OMIM: 610432,616260) PREDICTED: E3 ubiqu (196 aa)
initn: 1189 init1: 1189 opt: 1189 Z-score: 866.2 bits: 167.3 E(85289): 1.7e-41
Smith-Waterman score: 1279; 84.5% identity (84.5% similar) in 232 aa overlap (1-232:1-196)
10 20 30 40 50 60
pF1KE4 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCRLIPDEN
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPV------------
130 140 150 160
190 200 210 220 230
pF1KE4 PSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNHSNTT
::::::::::::::::::::::::::::
XP_011 ------------------------DFNIIEEALIRRVLDRSLLEYVNHSNTT
170 180 190
>>NP_061153 (OMIM: 612451) E3 ubiquitin-protein ligase R (228 aa)
initn: 494 init1: 190 opt: 233 Z-score: 190.8 bits: 42.6 E(85289): 0.00068
Smith-Waterman score: 471; 33.0% identity (64.1% similar) in 206 aa overlap (31-224:23-227)
10 20 30 40 50 60
pF1KE4 MGSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSC
:. : : ::::: ..::.. :::::: .:
NP_061 MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSAC
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 IATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYKNCAECDTLVCLSEMRAHIRTCQ
. :: .: .: ::. : . :: :... ....: .: : ::..:.:. ::.
NP_061 LQECLKPKKPVCGVCRSAL-APGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCS
60 70 80 90 100 110
130 140 150 160
pF1KE4 KYIDKY--GPLQELEETA--ARCV-------CPFC-QRELYEDSLLDHCITHHRSERRPV
:: . : ..... : : ::.: .... ...:..:: : .. . :
NP_061 KYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 FCPLCRLIPDENPSSFSGSLIRHLQVSHTLFYDDFIDFNIIEEALIRRVLDRSLLEYVNH
::.: .: .:. :... .:.: : . :: :.:... :: .. .::.::...
NP_061 VCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ
180 190 200 210 220
230
pF1KE4 SNTT
232 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:20:09 2016 done: Sun Nov 6 04:20:09 2016
Total Scan time: 5.750 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]