Result of FASTA (ccds) for
pFN21AE4020
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4020, 205 aa
1>>>pF1KE4020 205 - 205 aa - 205 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2413+/-0.000952; mu= 13.4522+/- 0.057
mean_var=68.0329+/-13.681, 0's: 0 Z-trim(104.4): 127 B-trim: 0 in 0/49
Lambda= 0.155494
statistics sampled from 7740 (7875) to 7740 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.242), width: 16
Scan time: 1.960
The best scores are: opt bits E(32554)
CCDS8679.1 RERGL gene_id:79785|Hs108|chr12 ( 205) 1337 308.9 1.4e-84
CCDS66332.1 RERGL gene_id:79785|Hs108|chr12 ( 204) 1226 284.0 4.4e-77
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 332 83.4 1e-16
CCDS9321.1 RASL11A gene_id:387496|Hs108|chr13 ( 242) 294 75.0 4.4e-14
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 275 70.7 7.8e-13
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 275 70.7 8.3e-13
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 270 69.5 1.5e-12
CCDS3490.1 RASL11B gene_id:65997|Hs108|chr4 ( 248) 270 69.6 1.9e-12
CCDS53753.1 RERG gene_id:85004|Hs108|chr12 ( 180) 257 66.6 1.1e-11
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 249 64.8 4.2e-11
CCDS10200.1 RASL12 gene_id:51285|Hs108|chr15 ( 266) 246 64.2 8.3e-11
>>CCDS8679.1 RERGL gene_id:79785|Hs108|chr12 (205 aa)
initn: 1337 init1: 1337 opt: 1337 Z-score: 1631.9 bits: 308.9 E(32554): 1.4e-84
Smith-Waterman score: 1337; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 SQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 VGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKE
130 140 150 160 170 180
190 200
pF1KE4 KRRPSGSKSMAKLINNVFGKRRKSV
:::::::::::::::::::::::::
CCDS86 KRRPSGSKSMAKLINNVFGKRRKSV
190 200
>>CCDS66332.1 RERGL gene_id:79785|Hs108|chr12 (204 aa)
initn: 1226 init1: 1226 opt: 1226 Z-score: 1497.3 bits: 284.0 E(32554): 4.4e-77
Smith-Waterman score: 1226; 100.0% identity (100.0% similar) in 187 aa overlap (19-205:18-204)
10 20 30 40 50 60
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPC
::::::::::::::::::::::::::::::::::::::::::
CCDS66 MNDVKLAVLGGEGTGKSALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPC
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 SQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 SQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 VGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 VGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKE
120 130 140 150 160 170
190 200
pF1KE4 KRRPSGSKSMAKLINNVFGKRRKSV
:::::::::::::::::::::::::
CCDS66 KRRPSGSKSMAKLINNVFGKRRKSV
180 190 200
>>CCDS8673.1 RERG gene_id:85004|Hs108|chr12 (199 aa)
initn: 362 init1: 126 opt: 332 Z-score: 413.6 bits: 83.4 E(32554): 1e-16
Smith-Waterman score: 332; 34.9% identity (65.1% similar) in 186 aa overlap (19-200:21-196)
10 20 30 40 50
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYD
::.::::::::: :: ..:: :... .. . ...:: :
CCDS86 MAKSAEVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 PCSQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFA---KALIYRIREPQTSHCKRAVE
. :. .. ....:..:::.::::.::.:: . : .. .:..:..
CCDS86 --TAGQEDTIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNV-------
70 80 90 100 110
120 130 140 150 160 170
pF1KE4 SAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILIN
...::::: :: : :.:. :::.::: : : : : :: .. .: .. ...
CCDS86 -TLILVGNKADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRR
120 130 140 150 160 170
180 190 200
pF1KE4 FKLKEK-RRPSGSKSMAKLINNVFGKRRKSV
.. : :: :.. . . ::... :
CCDS86 RMVQGKTRRRSSTTHVKQAINKMLTKISS
180 190
>>CCDS9321.1 RASL11A gene_id:387496|Hs108|chr13 (242 aa)
initn: 331 init1: 119 opt: 294 Z-score: 366.3 bits: 75.0 E(32554): 4.4e-14
Smith-Waterman score: 294; 35.1% identity (64.4% similar) in 174 aa overlap (19-185:42-210)
10 20 30 40
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLE
:. ::::::::::.: : ..:.. . .:
CCDS93 LAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVE
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 RKQLNLEIYDPCSQTQ------KAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRI
::.:.: : . .: .. ::.. ..::.::..::.:.: .:. . : .:
CCDS93 GDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHI
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 REPQTSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVE
:. . . .. :..:::: :: :.:.: ..: .:: : : :.:..:. .:
CCDS93 RKVHPDS-----KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVC
140 150 160 170 180
170 180 190 200
pF1KE4 MMFIRIIKDILINFKLK-EKRRPSGSKSMAKLINNVFGKRRKSV
.: .. :.. :. :.:: :
CCDS93 DVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSALG
190 200 210 220 230 240
>>CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 (219 aa)
initn: 273 init1: 127 opt: 275 Z-score: 343.9 bits: 70.7 E(32554): 7.8e-13
Smith-Waterman score: 275; 32.3% identity (61.5% similar) in 195 aa overlap (19-205:36-218)
10 20 30 40
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLE
:.:..:...:: .. ..:. :: .. ..
CCDS11 RPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRID
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 RKQLNLEIYDPCSQTQKAKFSLTSE--LHWADGFVIVYDISDRSSFAFA---KALIYRIR
. ::.: : .: :.:. . .. ..::.: :.:.:: :: . : ::::.:
CCDS11 DEPANLDILDTAGQ---AEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 EPQTSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEM
:. .. : ::::: :: ..:.: ::: :: : : : : ::: . ..
CCDS11 --------RTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYR-YYIDD
130 140 150 160 170
170 180 190 200
pF1KE4 MFIRIIKDILINFK---LKEKRRPSGSKSMAKLINNVFGKRRKSV
.: ....: . : : ... . ..:. : ... : :.. ::
CCDS11 VFHALVREIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
180 190 200 210
>>CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 (236 aa)
initn: 273 init1: 127 opt: 275 Z-score: 343.4 bits: 70.7 E(32554): 8.3e-13
Smith-Waterman score: 275; 32.3% identity (61.5% similar) in 195 aa overlap (19-205:53-235)
10 20 30 40
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLE
:.:..:...:: .. ..:. :: .. ..
CCDS58 RPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRID
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE4 RKQLNLEIYDPCSQTQKAKFSLTSE--LHWADGFVIVYDISDRSSFAFA---KALIYRIR
. ::.: : .: :.:. . .. ..::.: :.:.:: :: . : ::::.:
CCDS58 DEPANLDILDTAGQ---AEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVR
90 100 110 120 130
110 120 130 140 150 160
pF1KE4 EPQTSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEM
:. .. : ::::: :: ..:.: ::: :: : : : : ::: . ..
CCDS58 --------RTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYR-YYIDD
140 150 160 170 180 190
170 180 190 200
pF1KE4 MFIRIIKDILINFK---LKEKRRPSGSKSMAKLINNVFGKRRKSV
.: ....: . : : ... . ..:. : ... : :.. ::
CCDS58 VFHALVREIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
200 210 220 230
>>CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 (183 aa)
initn: 246 init1: 127 opt: 270 Z-score: 339.0 bits: 69.5 E(32554): 1.5e-12
Smith-Waterman score: 270; 32.0% identity (61.3% similar) in 194 aa overlap (20-205:1-182)
10 20 30 40 50 60
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPC
.:..:...:: .. ..:. :: .. .. . ::.: :
CCDS58 MTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTA
10 20 30 40
70 80 90 100 110
pF1KE4 SQTQKAKFSLTSE--LHWADGFVIVYDISDRSSFAFA---KALIYRIREPQTSHCKRAVE
.: :.:. . .. ..::.: :.:.:: :: . : ::::.: :. .
CCDS58 GQ---AEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVR--------RTDD
50 60 70 80 90
120 130 140 150 160 170
pF1KE4 SAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILIN
. : ::::: :: ..:.: ::: :: : : : : ::: . .. .: ....: .
CCDS58 TPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYR-YYIDDVFHALVREIRRK
100 110 120 130 140
180 190 200
pF1KE4 FK---LKEKRRPSGSKSMAKLINNVFGKRRKSV
: : ... . ..:. : ... : :.. ::
CCDS58 EKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
150 160 170 180
>>CCDS3490.1 RASL11B gene_id:65997|Hs108|chr4 (248 aa)
initn: 196 init1: 122 opt: 270 Z-score: 337.1 bits: 69.6 E(32554): 1.9e-12
Smith-Waterman score: 270; 32.8% identity (63.8% similar) in 174 aa overlap (19-187:48-210)
10 20 30 40
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLE
::.::::::::::.: : ..: ... .:
CCDS34 NAAASDCCVGAAGRRLVKIAVVGASGVGKTALVVRFLTKRFIGDYERNAGNLYTRQVQIE
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE4 RKQLNLEIYD-PCSQTQKAKFSLTSELH----WADGFVIVYDISDRSSFAFAKALIYRIR
. : :.. : : :... ..: . .:. :::. :::..:.: .:. . . : ..
CCDS34 GETLALQVQDTPGIQVHENSLSCSEQLNRCIRWADAVVIVFSITDYKSYELISQLHQHV-
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE4 EPQTSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEM
: : ... : .:.:: :: :...: . : .:: :.: :.:..:. .:
CCDS34 --QQLHL--GTRLPVVVVANKADLLHIKQVDPQLGLQLASMLGCSFYEVSVSENYNDVYS
140 150 160 170 180 190
170 180 190 200
pF1KE4 MFIRIIKDILINFKLKEKRRPSGSKSMAKLINNVFGKRRKSV
: . :.. ..:..::..
CCDS34 AFHVLCKEV------SHKQQPSSTPEKRRTSLIPRPKSPNMQDLKRRFKQALSAKVRTVT
200 210 220 230 240
>>CCDS53753.1 RERG gene_id:85004|Hs108|chr12 (180 aa)
initn: 231 init1: 126 opt: 257 Z-score: 323.3 bits: 66.6 E(32554): 1.1e-11
Smith-Waterman score: 257; 31.1% identity (62.3% similar) in 167 aa overlap (38-200:21-177)
10 20 30 40 50 60
pF1KE4 KYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPCSQTQKAK
:: :... .. . ...:: : .: . .
CCDS53 MAKSAEVKLAIFGRAGVGKSESTYRHQATIDDEVVSMEILDTAGQEDTIQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 FSLTSELHWADGFVIVYDISDRSSFAFA---KALIYRIREPQTSHCKRAVESAVFLVGNK
....:..:::.::::.::.:: . : .. .:..:.. ...:::::
CCDS53 RE--GHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNV--------TLILVGNK
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 RDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKEK-RR
:: : :.:. :::.::: : : : : :: .. .: .. ... .. : ::
CCDS53 ADLDHSRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREVRRRRMVQGKTRR
110 120 130 140 150 160
190 200
pF1KE4 PSGSKSMAKLINNVFGKRRKSV
:.. . . ::... :
CCDS53 RSSTTHVKQAINKMLTKISS
170 180
>>CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 (208 aa)
initn: 224 init1: 106 opt: 249 Z-score: 312.7 bits: 64.8 E(32554): 4.2e-11
Smith-Waterman score: 249; 28.9% identity (61.8% similar) in 173 aa overlap (19-183:28-189)
10 20 30 40 50
pF1KE4 MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQ
:::..:. : :. .: ..:. : :: .. .
CCDS31 MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW
10 20 30 40 50 60
60 70 80 90 100
pF1KE4 LNLEIYDPCSQTQKAKFSLTSE--LHWADGFVIVYDISDRSSFAFA---KALIYRIREPQ
:.. : .: . :: : .. .:::.:::...:..:: . . :: :... .
CCDS31 AILDVLDTAGQEE---FSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRE
70 80 90 100 110
110 120 130 140 150 160
pF1KE4 TSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMF-
. ..::.:: :: :.:.. :.:...: .. . : :: . :.:. :
CCDS31 SF--------PMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFH
120 130 140 150 160
170 180 190 200
pF1KE4 --IRIIKDILINFKLKEKRRPSGSKSMAKLINNVFGKRRKSV
.:.:.. . . . :.:..
CCDS31 DLVRVIRQQIPEKSQKKKKKTKWRGDRATGTHKLQCVIL
170 180 190 200
205 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:26:17 2016 done: Sun Nov 6 03:26:17 2016
Total Scan time: 1.960 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]