Result of FASTA (omim) for
pFN21AE4001
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4001, 186 aa
1>>>pF1KE4001 186 - 186 aa - 186 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2532+/-0.000437; mu= 13.7315+/- 0.027
mean_var=88.4582+/-18.965, 0's: 0 Z-trim(113.0): 290 B-trim: 2012 in 3/49
Lambda= 0.136366
statistics sampled from 21767 (22197) to 21767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.26), width: 16
Scan time: 4.200
The best scores are: opt bits E(85289)
NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 1245 254.7 6.3e-68
NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 1182 242.3 3.4e-64
NP_001243058 (OMIM: 616597) ADP-ribosylation facto ( 147) 836 174.1 8.9e-44
NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 402 88.8 5.1e-18
NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 391 86.7 2.3e-17
NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 391 86.7 2.3e-17
NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 391 86.7 2.3e-17
NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 391 86.7 2.3e-17
NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 389 86.3 3.1e-17
XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 386 85.7 4.6e-17
NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 386 85.7 4.6e-17
NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 375 83.5 2.1e-16
NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 367 81.9 6.3e-16
NP_878899 (OMIM: 608922,612291) ADP-ribosylation f ( 428) 369 82.7 8.7e-16
NP_001167621 (OMIM: 608922,612291) ADP-ribosylatio ( 428) 369 82.7 8.7e-16
NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 360 80.6 1.6e-15
XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 356 79.8 2.8e-15
NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 356 79.8 2.8e-15
NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 344 77.4 1.5e-14
XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 344 77.4 1.5e-14
XP_011510837 (OMIM: 608922,612291) PREDICTED: ADP- ( 403) 336 76.2 7.5e-14
XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 332 75.1 7.9e-14
NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 332 75.1 7.9e-14
NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 331 74.9 8.7e-14
NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 331 74.9 9e-14
NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 331 74.9 9e-14
NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 331 74.9 9e-14
NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 331 74.9 9e-14
NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 331 74.9 9e-14
NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 328 74.3 1.3e-13
NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 318 72.3 5e-13
NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 318 72.3 5e-13
NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 318 72.3 5e-13
XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 318 72.3 5e-13
NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 317 72.1 5.9e-13
XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 318 72.6 8.7e-13
NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 312 71.0 9.1e-13
XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 314 71.6 9.5e-13
XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 312 71.1 1e-12
NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 312 71.1 1e-12
NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 318 72.8 1.1e-12
NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 309 70.5 1.7e-12
NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 312 71.6 2.5e-12
XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 305 69.8 3.1e-12
XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 305 69.8 3.1e-12
NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 305 69.8 3.1e-12
NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 305 69.8 3.1e-12
NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 305 69.8 3.1e-12
XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 305 69.8 3.1e-12
XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 302 69.0 3.6e-12
>>NP_620150 (OMIM: 616597) ADP-ribosylation factor-like (186 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1340.4 bits: 254.7 E(85289): 6.3e-68
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
130 140 150 160 170 180
pF1KE4 SKSRRS
::::::
NP_620 SKSRRS
>>NP_060654 (OMIM: 616596) ADP-ribosylation factor-like (186 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1273.5 bits: 242.3 E(85289): 3.4e-64
Smith-Waterman score: 1182; 91.9% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
:.::...:::::..:::::::::::::::::::::::::::::::.:::::::::::::.
NP_060 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
::::::::.::::::::::::::::::::.:::::.::::.::::::.::::::::::::
NP_060 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
:::::::::::::::.:::::.::::::::::::::::::::::::::::::::::::::
NP_060 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
130 140 150 160 170 180
pF1KE4 SKSRRS
::::::
NP_060 SKSRRS
>>NP_001243058 (OMIM: 616597) ADP-ribosylation factor-li (147 aa)
initn: 834 init1: 834 opt: 836 Z-score: 906.9 bits: 174.1 E(85289): 8.9e-44
Smith-Waterman score: 836; 94.8% identity (95.6% similar) in 135 aa overlap (1-134:1-135)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 QGIPVLVLG-NKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQ
:::: : . :::
NP_001 QGIPESVCHPGPRDLLLLHLLQRKGQH
130 140
>>NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 [Ho (175 aa)
initn: 403 init1: 346 opt: 402 Z-score: 444.5 bits: 88.8 E(85289): 5.1e-18
Smith-Waterman score: 402; 35.3% identity (72.4% similar) in 170 aa overlap (15-183:8-175)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
.: ..::.. ..::. .::::.. . :: . :::::::.. .
NP_001 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQ-SVTTIPTVGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
: :: ...::.::: ..: .:..: :.......:: ::...:. ...::: ... ..
NP_001 TYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREM
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEK-DNIDITLQWLIQ
. .:...::.::: :. .:. ::..:. :.::. :: . :.. : :: .
NP_001 RDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQP-SCATSGDGLYEGLTWLTS
120 130 140 150 160 170
180
pF1KE4 HSKSRRS
. ::
NP_001 NYKS
>>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 391 init1: 309 opt: 391 Z-score: 432.6 bits: 86.7 E(85289): 2.3e-17
Smith-Waterman score: 391; 30.6% identity (71.7% similar) in 180 aa overlap (6-185:3-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
: . . ::.:: :.::.. .:::. .::::.. . :.. :::.:::.. .
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
:... .::.::: ..: .:..: .........::. :.:... ...:: .: . .:
NP_001 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. .::..::.:::.:.. :. .:..: ... :. . :.. :.:: ..
NP_001 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQ
120 130 140 150 160 170
pF1KE4 SKSRRS
....
NP_001 LRNQK
180
>>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa)
initn: 391 init1: 309 opt: 391 Z-score: 432.6 bits: 86.7 E(85289): 2.3e-17
Smith-Waterman score: 391; 30.6% identity (71.7% similar) in 180 aa overlap (6-185:3-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
: . . ::.:: :.::.. .:::. .::::.. . :.. :::.:::.. .
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
:... .::.::: ..: .:..: .........::. :.:... ...:: .: . .:
NP_001 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. .::..::.:::.:.. :. .:..: ... :. . :.. :.:: ..
NP_001 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQ
120 130 140 150 160 170
pF1KE4 SKSRRS
....
NP_001 LRNQK
180
>>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 391 init1: 309 opt: 391 Z-score: 432.6 bits: 86.7 E(85289): 2.3e-17
Smith-Waterman score: 391; 30.6% identity (71.7% similar) in 180 aa overlap (6-185:3-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
: . . ::.:: :.::.. .:::. .::::.. . :.. :::.:::.. .
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
:... .::.::: ..: .:..: .........::. :.:... ...:: .: . .:
NP_001 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. .::..::.:::.:.. :. .:..: ... :. . :.. :.:: ..
NP_001 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQ
120 130 140 150 160 170
pF1KE4 SKSRRS
....
NP_001 LRNQK
180
>>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 391 init1: 309 opt: 391 Z-score: 432.6 bits: 86.7 E(85289): 2.3e-17
Smith-Waterman score: 391; 30.6% identity (71.7% similar) in 180 aa overlap (6-185:3-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
: . . ::.:: :.::.. .:::. .::::.. . :.. :::.:::.. .
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
:... .::.::: ..: .:..: .........::. :.:... ...:: .: . .:
NP_001 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. .::..::.:::.:.. :. .:..: ... :. . :.. :.:: ..
NP_001 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQ
120 130 140 150 160 170
pF1KE4 SKSRRS
....
NP_001 LRNQK
180
>>NP_001168 (OMIM: 603425) ADP-ribosylation factor-like (181 aa)
initn: 380 init1: 332 opt: 389 Z-score: 430.5 bits: 86.3 E(85289): 3.1e-17
Smith-Waterman score: 389; 32.8% identity (71.8% similar) in 174 aa overlap (12-185:9-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
:..:: .::.. ..::. .::::.. . :. :::.:::.. .
NP_001 MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
: :. ...::.::: .: .:. : ...:..:.::. :...: ::.:: .:.. .:
NP_001 TYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. ..:..::.:. :. .:. ....: :..::. .. : . ..: ...::..
NP_001 RKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVET
120 130 140 150 160 170
pF1KE4 SKSRRS
:::.
NP_001 LKSRQ
180
>>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa)
initn: 384 init1: 319 opt: 386 Z-score: 427.3 bits: 85.7 E(85289): 4.6e-17
Smith-Waterman score: 386; 30.8% identity (71.4% similar) in 185 aa overlap (1-185:1-181)
10 20 30 40 50 60
pF1KE4 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI
: .:..:: :.:. :.::.. .:::. .::::.. . :.. :::.:::.. .
XP_005 MGNIFGNLL---KSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL
:... .::.::: ..: .:..: .........::. :.:... ...:: .: . .:
XP_005 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH
. .::..::.:::.:.. :. .:..: ... :. . :.. :.:: ..
XP_005 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQ
120 130 140 150 160 170
pF1KE4 SKSRRS
:...
XP_005 LKNKK
180
186 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:21:58 2016 done: Sun Nov 6 05:21:59 2016
Total Scan time: 4.200 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]