Result of FASTA (ccds) for
pFN21AE3995
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3995, 283 aa
1>>>pF1KE3995 283 - 283 aa - 283 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5130+/-0.000643; mu= 14.7390+/- 0.039
mean_var=74.5865+/-14.751, 0's: 0 Z-trim(112.2): 39 B-trim: 0 in 0/51
Lambda= 0.148506
statistics sampled from 12941 (12979) to 12941 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.399), width: 16
Scan time: 2.170
The best scores are: opt bits E(32554)
CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 ( 283) 2015 440.3 7.3e-124
CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 ( 278) 1157 256.5 1.6e-68
CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 ( 293) 676 153.5 1.7e-37
CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 ( 296) 664 150.9 1e-36
CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 ( 255) 604 138.0 6.7e-33
CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 ( 275) 283 69.2 3.6e-12
>>CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 (283 aa)
initn: 2015 init1: 2015 opt: 2015 Z-score: 2337.2 bits: 440.3 E(32554): 7.3e-124
Smith-Waterman score: 2015; 100.0% identity (100.0% similar) in 283 aa overlap (1-283:1-283)
10 20 30 40 50 60
pF1KE3 MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 VDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QEGLRKWMVQHGGDGWVVEENRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QEGLRKWMVQHGGDGWVVEENRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHV
190 200 210 220 230 240
250 260 270 280
pF1KE3 FSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
:::::::::::::::::::::::::::::::::::::::::::
CCDS12 FSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
250 260 270 280
>>CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 (278 aa)
initn: 856 init1: 856 opt: 1157 Z-score: 1343.9 bits: 256.5 E(32554): 1.6e-68
Smith-Waterman score: 1157; 57.7% identity (79.0% similar) in 286 aa overlap (1-283:1-278)
10 20 30 40 50 60
pF1KE3 MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRAL
::: .:: :.:: .: ::: ::::::. ::::::::.:. ::: :::.:: .
CCDS12 MGARLSR---RRLPA---DPSLALD--ALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDI
10 20 30 40 50
70 80 90 100 110
pF1KE3 VDGQALWLLILARDHGATGRALLHLARSC--QSPARNARP-CPLGRFCARRPIGRNLIRN
::: ..::: ::::..: :::: .:. : .. .. : : :.:.: : :.::::: :
CCDS12 VDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 PCGQEGLRKWMVQHGGDGWVVEENRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPE
::..:.: : :.:::.::..:.: : :::::::::::::: :: :.:..:: ::.: :
CCDS12 SCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHV
::::..:::::.::::::.. ::.:.: :.:::. . . :::: :::. ::.. .: .:
CCDS12 LLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQV
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 THVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
.:::.:. :.:.::::. :.:.. :.::::: ::.::: ::.:::
CCDS12 SHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
240 250 260 270
>>CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 (293 aa)
initn: 684 init1: 450 opt: 676 Z-score: 786.6 bits: 153.5 E(32554): 1.7e-37
Smith-Waterman score: 676; 40.8% identity (64.0% similar) in 272 aa overlap (18-283:4-262)
10 20 30 40 50
pF1KE3 MGASVSRGRAARVPAPEPEPEEALD-LSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRA
:. . ::: ...:: ..:: ...::: : :: :: :: ::
CCDS13 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRD
10 20 30 40
60 70 80 90 100 110
pF1KE3 LVDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPC
:.: ..:: :. : .... ..:. . . : : . :::.::::
CCDS13 LIDLMTLWKRKCLRE----G----FITKDWDQPVADWKI-----FYFLRSLHRNLLRNPC
50 60 70 80 90
120 130 140 150 160 170
pF1KE3 GQEGLRKWMVQ-HGGDGWVVEE----NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGL
..: . :... .::: : :: . : : . ::::. : :.:..:: ::
CCDS13 AEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGY
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 WPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNAC
: ::::. : .: :.::..:: : :: :.: ::: .:. :: .: : : :::: .
CCDS13 WEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATW
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 LHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
.:...::. :::.. :.: :.:::.::: :: ::::::..: ...
CCDS13 TEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPG
220 230 240 250 260 270
CCDS13 QKHGQEEAAQSPYRAVVQIF
280 290
>>CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 (296 aa)
initn: 685 init1: 265 opt: 664 Z-score: 772.6 bits: 150.9 E(32554): 1e-36
Smith-Waterman score: 664; 41.8% identity (65.1% similar) in 275 aa overlap (16-278:32-294)
10 20 30 40
pF1KE3 MGASVSRGRAARVPAPEPEPEE-----ALDLSQLPPELLLVVLSH
:: . :: : :..:: ::: ::.
CCDS13 DGDGDPESVGQPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 VPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCP
.: :. :: :: :. :::: :::: ...: . .. .. :. .
CCDS13 LPAAELVQACRLVCLRWKELVDGAPLWLLK-CQQEGLVPEGGVEEERDHWQQFY------
70 80 90 100 110
110 120 130 140 150
pF1KE3 LGRFCARRPIGRNLIRNPCGQEGLRKWM-VQHGGDGWVVEE--NRTTVPGAPSQTC---F
: ..: :::.:::::.: :. : :.:::::: ::: . . : . ... :
CCDS13 ---FLSKRR--RNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYF
120 130 140 150 160
160 170 180 190 200 210
pF1KE3 VTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQT
..:: :: : ::.::. :: : ::::. . : :.::...: :.::.:.: :.::. ...
CCDS13 ASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHEN
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE3 VLDKFSAVPDPIPQWNNNAC-LHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTN
:: .::. .:: .... ....:.:.. ::::: ::: :::. .: : .::::::
CCDS13 VLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTN
230 240 250 260 270 280
280
pF1KE3 SSVIVRVRLS
::: :
CCDS13 SSVWVEP
290
>>CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 (255 aa)
initn: 629 init1: 396 opt: 604 Z-score: 704.1 bits: 138.0 E(32554): 6.7e-33
Smith-Waterman score: 604; 39.4% identity (63.7% similar) in 259 aa overlap (25-278:5-250)
10 20 30 40 50 60
pF1KE3 MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRAL
....:: ..:: ...::: : :: :: :: :: :
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDL
10 20 30 40
70 80 90 100 110 120
pF1KE3 VDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCG
.: .:: :. : .... ..:. . . : : . :::..:::.
CCDS13 IDLVTLWKRKCLRE----G----FITEDWDQPVADWKI-----FYFLRSLHRNLLHNPCA
50 60 70 80
130 140 150 160 170
pF1KE3 QEGLRKWMVQ-HGGDGWVVEE----NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLW
.::.. : .. .::: : ::. .: :. . ::::. : :.::.::. :: :
CCDS13 EEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYW
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE3 PELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACL
::.:. : .: :.::..:: : : :.: ::::.. .. : :. : : : ..
CCDS13 EELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWR
150 160 170 180 190 200
240 250 260 270 280
pF1KE3 HVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
.:.:.::: :::.. :.: : ::..::: :: ::::::. .
CCDS13 EVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP
210 220 230 240 250
>>CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 (275 aa)
initn: 318 init1: 158 opt: 283 Z-score: 331.9 bits: 69.2 E(32554): 3.6e-12
Smith-Waterman score: 283; 34.4% identity (58.5% similar) in 183 aa overlap (107-281:98-274)
80 90 100 110 120 130
pF1KE3 ATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGLRKWM-VQHGGDG
:::. :::.:.: . ::. . . :
CCDS12 HARQLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSP-NPEGINIYEPAPPTGPT
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE3 WVVEENRTTVPGAPSQTC-FVTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGA
:. . : .: . . :: :.: .:: :::: ::::. . : : ::.
CCDS12 QRPLETLGNFRGWYIRTEKLQQNQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFED
130 140 150 160 170 180
200 210 220 230 240
pF1KE3 RHDSGCMYRLLVQLLDANQ-TVLDKFSAVP-----DPIPQWNNNACLHVTHVFSNIKMGV
. ..:.:.: : :: :.. ::. . ..: : .: ..:.::: . ::
CCDS12 SRLDACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRW-----VQVSHVFRHYGPGV
190 200 210 220 230 240
250 260 270 280
pF1KE3 RFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
::. : :.... . .: .:::.::: :..:
CCDS12 RFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE
250 260 270
283 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:08:22 2016 done: Sun Nov 6 08:08:22 2016
Total Scan time: 2.170 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]