Result of FASTA (ccds) for
pFN21AE3983
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3983, 237 aa
1>>>pF1KE3983 237 - 237 aa - 237 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1291+/-0.000957; mu= 9.3337+/- 0.057
mean_var=64.9356+/-13.377, 0's: 0 Z-trim(104.8): 54 B-trim: 332 in 1/49
Lambda= 0.159160
statistics sampled from 8056 (8111) to 8056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.249), width: 16
Scan time: 1.840
The best scores are: opt bits E(32554)
CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 ( 237) 1621 381.0 3.7e-106
CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 ( 260) 485 120.1 1.4e-27
CCDS12434.1 KCTD15 gene_id:79047|Hs108|chr19 ( 234) 367 93.0 1.8e-19
CCDS46039.1 KCTD15 gene_id:79047|Hs108|chr19 ( 283) 367 93.1 2.1e-19
CCDS11888.1 KCTD1 gene_id:284252|Hs108|chr18 ( 257) 359 91.2 6.9e-19
CCDS9396.1 KCTD4 gene_id:386618|Hs108|chr13 ( 259) 322 82.7 2.5e-16
CCDS41889.1 KCNRG gene_id:283518|Hs108|chr13 ( 229) 291 75.6 3.1e-14
CCDS9424.1 KCNRG gene_id:283518|Hs108|chr13 ( 272) 291 75.6 3.7e-14
CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 ( 325) 283 73.8 1.6e-13
CCDS60908.1 KCTD14 gene_id:65987|Hs108|chr11 ( 225) 264 69.4 2.2e-12
CCDS8255.2 KCTD14 gene_id:65987|Hs108|chr11 ( 255) 264 69.4 2.5e-12
CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5 ( 428) 266 69.9 3e-12
CCDS55117.1 KCTD7 gene_id:154881|Hs108|chr7 ( 288) 260 68.5 5.4e-12
CCDS5534.1 KCTD7 gene_id:154881|Hs108|chr7 ( 289) 260 68.5 5.4e-12
CCDS2330.1 KCTD18 gene_id:130535|Hs108|chr2 ( 426) 258 68.0 1.1e-11
CCDS32545.1 KCTD11 gene_id:147040|Hs108|chr17 ( 232) 244 64.8 5.6e-11
CCDS11227.1 TNFAIP1 gene_id:7126|Hs108|chr17 ( 316) 245 65.0 6.4e-11
>>CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 (237 aa)
initn: 1621 init1: 1621 opt: 1621 Z-score: 2019.3 bits: 381.0 E(32554): 3.7e-106
Smith-Waterman score: 1621; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237)
10 20 30 40 50 60
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD
190 200 210 220 230
>>CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 (260 aa)
initn: 476 init1: 476 opt: 485 Z-score: 608.8 bits: 120.1 E(32554): 1.4e-27
Smith-Waterman score: 485; 71.4% identity (89.8% similar) in 98 aa overlap (10-107:1-98)
10 20 30 40 50 60
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
:.::.::::::.::::::.::: .:::::::::.: .:: :: ::: ::::
CCDS31 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
:: .:::.:::::::.: :: ::.:. :::.::::::..:::. :..
CCDS31 DGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG
CCDS31 LNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNL
120 130 140 150 160 170
>>CCDS12434.1 KCTD15 gene_id:79047|Hs108|chr19 (234 aa)
initn: 382 init1: 227 opt: 367 Z-score: 463.2 bits: 93.0 E(32554): 1.8e-19
Smith-Waterman score: 367; 56.4% identity (83.0% similar) in 94 aa overlap (13-105:57-150)
10 20 30 40
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMF
:: ..::::.::.::.:::.:::: .. .:
CCDS12 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE3 GGDFPTARDP-QGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPL
.: : . : . .::::::: .:::::.:::::.: :: :::.:.:: .:: .::..:.
CCDS12 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE3 IQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFT
.. :
CCDS12 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN
150 160 170 180 190 200
>>CCDS46039.1 KCTD15 gene_id:79047|Hs108|chr19 (283 aa)
initn: 382 init1: 227 opt: 367 Z-score: 461.7 bits: 93.1 E(32554): 2.1e-19
Smith-Waterman score: 367; 56.4% identity (83.0% similar) in 94 aa overlap (13-105:57-150)
10 20 30 40
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMF
:: ..::::.::.::.:::.:::: .. .:
CCDS46 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE3 GGDFPTARDP-QGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPL
.: : . : . .::::::: .:::::.:::::.: :: :::.:.:: .:: .::..:.
CCDS46 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE3 IQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFT
.. :
CCDS46 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN
150 160 170 180 190 200
>>CCDS11888.1 KCTD1 gene_id:284252|Hs108|chr18 (257 aa)
initn: 356 init1: 217 opt: 359 Z-score: 452.6 bits: 91.2 E(32554): 6.9e-19
Smith-Waterman score: 359; 33.7% identity (59.7% similar) in 196 aa overlap (13-205:31-217)
10 20 30 40
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMF
:: ..::::.::.::.:::.::.: .: .:
CCDS11 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 GGDFPTARDP-QGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPL
: : . : . .::::::: .:::.:::::::.: .: :::.. :: .:: ..:..:.
CCDS11 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 IQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFT
. .. : : . : .: .. ... . : . . . : .
CCDS11 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN
130 140 150 160 170 180
170 180 190 200 210
pF1KE3 K-WNKHMMDTRDCQVSFTF-GPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANE
::. :. . : . : : .. :...: . ..:: :
CCDS11 AGWNH---DSTHV-IRFPLNGYCHLNS-----VQVLERLQQRGFEIVGSCGGGVDSSQFS
190 200 210 220 230
220 230
pF1KE3 NTVEHNWTFCRLARKTDD
CCDS11 EYVLRRELRRTPRVPSVIRIKQEPLD
240 250
>>CCDS9396.1 KCTD4 gene_id:386618|Hs108|chr13 (259 aa)
initn: 306 init1: 306 opt: 322 Z-score: 406.6 bits: 82.7 E(32554): 2.5e-16
Smith-Waterman score: 322; 39.7% identity (70.5% similar) in 156 aa overlap (14-161:35-188)
10 20 30 40
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFG
.::::::.:: :. :::.:::..: .. .
CCDS93 INRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 GDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ
: . : .:.::::::: :::.::::::..:: :: :.: .:: .::.:.:.. : .
CCDS93 GKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE
70 80 90 100 110 120
110 120 130 140 150
pF1KE3 CLN---DPKPLYPMDT-FEEVVE-LSSTRKLSKYSN-P--VAVIITQLTITTKVHSLLEG
.. . . : : .: : :... . .. : . : : .. : .......: : :.:
CCDS93 EVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSK--SRLDG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 ISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSE
. . :.
CCDS93 FPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSL
190 200 210 220 230 240
>>CCDS41889.1 KCNRG gene_id:283518|Hs108|chr13 (229 aa)
initn: 266 init1: 266 opt: 291 Z-score: 369.0 bits: 75.6 E(32554): 3.1e-14
Smith-Waterman score: 291; 35.5% identity (64.5% similar) in 152 aa overlap (14-160:7-157)
10 20 30 40 50 60
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
:::::::...:: ..:. ..: : :. :. : . :. :.::
CCDS41 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
:: :: ..:.:::: .: :: .:... :..:: ::... :.. :: : : : .. ::
CCDS41 DGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEV
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 VELSST-----RKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQV
:: . : ... :. . .. ..:. :. : .:.:
CCDS41 HFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 SFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKT
CCDS41 YHDLVFQCGSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGMFL
180 190 200 210 220
>>CCDS9424.1 KCNRG gene_id:283518|Hs108|chr13 (272 aa)
initn: 294 init1: 266 opt: 291 Z-score: 367.7 bits: 75.6 E(32554): 3.7e-14
Smith-Waterman score: 291; 35.5% identity (64.5% similar) in 152 aa overlap (14-160:7-157)
10 20 30 40 50 60
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
:::::::...:: ..:. ..: : :. :. : . :. :.::
CCDS94 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
:: :: ..:.:::: .: :: .:... :..:: ::... :.. :: : : : .. ::
CCDS94 DGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEV
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 VELSST-----RKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQV
:: . : ... :. . .. ..:. :. : .:.:
CCDS94 HFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 SFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKT
CCDS94 YHDLVFQCGSDSTTDNQTGVRYVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVS
180 190 200 210 220 230
>>CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 (325 aa)
initn: 280 init1: 195 opt: 283 Z-score: 356.5 bits: 73.8 E(32554): 1.6e-13
Smith-Waterman score: 283; 42.1% identity (69.2% similar) in 107 aa overlap (9-113:31-137)
10 20 30
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSML
.. : : :::::..:.: :.. :::.:
CCDS94 MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GAMFGGDFPT--ARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFY
:: . : ::: .: .:.:::: ::::.:..:: .:.:: : : . :..::...
CCDS94 WRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 QIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGI
.. :.. :. :. :
CCDS94 ELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLE
130 140 150 160 170 180
>>CCDS60908.1 KCTD14 gene_id:65987|Hs108|chr11 (225 aa)
initn: 244 init1: 191 opt: 264 Z-score: 335.7 bits: 69.4 E(32554): 2.2e-12
Smith-Waterman score: 264; 29.1% identity (59.2% similar) in 206 aa overlap (10-205:1-198)
10 20 30 40 50 60
pF1KE3 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
:. : :::::...::.: :: ..: : :. ::.. .. : .: .::::
CCDS60 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
. :: .:..:::.. .: ... . .::.::.:.::.. :.: .:. :.:
CCDS60 PSTYFRPILDYLRTGQ--VPT--QHIPEVYREAQFYEIKPLVKLLED----MPQIFGEQV
60 70 80 90 100
130 140 150 160 170
pF1KE3 VELSSTRKLSKYSNPVAVIITQL---TITTKVHSLL------EGISNYFTKWNKHMMDTR
. . .. ::. . ... .::.. :.: : . :... ..: .
CCDS60 SRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKK
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 DCQVSFTFGPCDYHQEVSLRVHLMEY-ITKQGFTIRNTRVHHMSERANENTVEHNWTFCR
. ::: . : .: .:. : ::. .
CCDS60 MFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFT
170 180 190 200 210 220
pF1KE3 LARKTDD
CCDS60 WW
237 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:21:53 2016 done: Sun Nov 6 08:21:53 2016
Total Scan time: 1.840 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]