Result of FASTA (omim) for
pFN21AE3982
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3982, 329 aa
1>>>pF1KE3982 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9126+/-0.000652; mu= 7.3272+/- 0.040
mean_var=229.3330+/-51.469, 0's: 0 Z-trim(111.8): 508 B-trim: 194 in 1/48
Lambda= 0.084692
statistics sampled from 19852 (20520) to 19852 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.241), width: 16
Scan time: 6.750
The best scores are: opt bits E(85289)
NP_543150 (OMIM: 615050) ankyrin repeat and SOCS b ( 329) 2190 281.4 1.8e-75
XP_005262816 (OMIM: 615050) PREDICTED: ankyrin rep ( 329) 2190 281.4 1.8e-75
XP_011529919 (OMIM: 615050) PREDICTED: ankyrin rep ( 276) 1778 231.0 2.3e-60
XP_011529918 (OMIM: 615050) PREDICTED: ankyrin rep ( 284) 1778 231.0 2.3e-60
NP_543149 (OMIM: 300626) ankyrin repeat and SOCS b ( 323) 1183 158.4 1.9e-38
NP_001012428 (OMIM: 300626) ankyrin repeat and SOC ( 302) 1004 136.4 7.2e-32
XP_005274503 (OMIM: 300890) PREDICTED: ankyrin rep ( 294) 906 124.5 2.8e-28
NP_001026909 (OMIM: 300890) ankyrin repeat and SOC ( 294) 906 124.5 2.8e-28
XP_016884772 (OMIM: 300890) PREDICTED: ankyrin rep ( 377) 906 124.6 3.3e-28
NP_076992 (OMIM: 300890) ankyrin repeat and SOCS b ( 262) 806 112.2 1.3e-24
NP_001162003 (OMIM: 300890) ankyrin repeat and SOC ( 262) 806 112.2 1.3e-24
XP_016884775 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 806 112.3 1.5e-24
XP_016884774 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 806 112.3 1.5e-24
NP_001188512 (OMIM: 300626) ankyrin repeat and SOC ( 306) 798 111.3 2.7e-24
NP_078977 (OMIM: 615055) ankyrin repeat and SOCS b ( 278) 696 98.8 1.5e-20
XP_011543760 (OMIM: 300890) PREDICTED: ankyrin rep ( 265) 675 96.2 8.4e-20
XP_016884773 (OMIM: 300890) PREDICTED: ankyrin rep ( 348) 676 96.5 9e-20
XP_011543762 (OMIM: 300890) PREDICTED: ankyrin rep ( 233) 575 83.9 3.7e-16
NP_001162002 (OMIM: 300890) ankyrin repeat and SOC ( 252) 443 67.8 2.8e-11
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 369 59.9 4.5e-08
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 369 59.9 4.5e-08
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 369 59.9 4.5e-08
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 369 59.9 4.6e-08
XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 369 59.9 4.6e-08
XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 369 59.9 4.6e-08
XP_016868816 (OMIM: 182900,612641) PREDICTED: anky (1807) 369 59.9 4.6e-08
NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform (1856) 369 59.9 4.7e-08
NP_000028 (OMIM: 182900,612641) ankyrin-1 isoform (1880) 369 59.9 4.7e-08
NP_065209 (OMIM: 182900,612641) ankyrin-1 isoform (1881) 369 60.0 4.7e-08
XP_011542804 (OMIM: 182900,612641) PREDICTED: anky (1889) 369 60.0 4.8e-08
XP_016868815 (OMIM: 182900,612641) PREDICTED: anky (1892) 369 60.0 4.8e-08
NP_001135918 (OMIM: 182900,612641) ankyrin-1 isofo (1897) 369 60.0 4.8e-08
XP_016868814 (OMIM: 182900,612641) PREDICTED: anky (1908) 369 60.0 4.8e-08
XP_011542803 (OMIM: 182900,612641) PREDICTED: anky (1913) 369 60.0 4.8e-08
XP_011542802 (OMIM: 182900,612641) PREDICTED: anky (1914) 369 60.0 4.8e-08
XP_005273533 (OMIM: 182900,612641) PREDICTED: anky (1921) 369 60.0 4.8e-08
XP_016868813 (OMIM: 182900,612641) PREDICTED: anky (1922) 369 60.0 4.8e-08
XP_016868812 (OMIM: 182900,612641) PREDICTED: anky (1936) 369 60.0 4.8e-08
XP_016868811 (OMIM: 182900,612641) PREDICTED: anky (1937) 369 60.0 4.8e-08
XP_016868810 (OMIM: 182900,612641) PREDICTED: anky (1940) 369 60.0 4.8e-08
XP_011542798 (OMIM: 182900,612641) PREDICTED: anky (1944) 369 60.0 4.8e-08
XP_016868809 (OMIM: 182900,612641) PREDICTED: anky (1946) 369 60.0 4.8e-08
XP_011542797 (OMIM: 182900,612641) PREDICTED: anky (1953) 369 60.0 4.8e-08
XP_011542796 (OMIM: 182900,612641) PREDICTED: anky (1954) 369 60.0 4.8e-08
XP_016868808 (OMIM: 182900,612641) PREDICTED: anky (1961) 369 60.0 4.9e-08
XP_011542793 (OMIM: 182900,612641) PREDICTED: anky (1968) 369 60.0 4.9e-08
XP_011542792 (OMIM: 182900,612641) PREDICTED: anky (1969) 369 60.0 4.9e-08
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 347 57.2 2.9e-07
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763) 347 57.2 2.9e-07
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 347 57.2 2.9e-07
>>NP_543150 (OMIM: 615050) ankyrin repeat and SOCS box p (329 aa)
initn: 2190 init1: 2190 opt: 2190 Z-score: 1476.0 bits: 281.4 E(85289): 1.8e-75
Smith-Waterman score: 2190; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE3 MSVLEENRPFAQQLSNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MSVLEENRPFAQQLSNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 VTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 TLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 HECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 AQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRLC
250 260 270 280 290 300
310 320
pF1KE3 IRSYIGKPRLHLIPQLQLPTLLKNFLQYR
:::::::::::::::::::::::::::::
NP_543 IRSYIGKPRLHLIPQLQLPTLLKNFLQYR
310 320
>>XP_005262816 (OMIM: 615050) PREDICTED: ankyrin repeat (329 aa)
initn: 2190 init1: 2190 opt: 2190 Z-score: 1476.0 bits: 281.4 E(85289): 1.8e-75
Smith-Waterman score: 2190; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE3 MSVLEENRPFAQQLSNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSVLEENRPFAQQLSNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRLC
250 260 270 280 290 300
310 320
pF1KE3 IRSYIGKPRLHLIPQLQLPTLLKNFLQYR
:::::::::::::::::::::::::::::
XP_005 IRSYIGKPRLHLIPQLQLPTLLKNFLQYR
310 320
>>XP_011529919 (OMIM: 615050) PREDICTED: ankyrin repeat (276 aa)
initn: 1778 init1: 1778 opt: 1778 Z-score: 1204.7 bits: 231.0 E(85289): 2.3e-60
Smith-Waterman score: 1778; 100.0% identity (100.0% similar) in 264 aa overlap (66-329:13-276)
40 50 60 70 80 90
pF1KE3 AILSHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYN
::::::::::::::::::::::::::::::
XP_011 MPLCNGGNLAVTGSWADRSPLHEAASQGRLLALRTLLSQGYN
10 20 30 40
100 110 120 130 140 150
pF1KE3 VNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 LEYGAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYGAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFH
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE3 CIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS
170 180 190 200 210 220
280 290 300 310 320
pF1KE3 SSMVERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSMVERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
230 240 250 260 270
>>XP_011529918 (OMIM: 615050) PREDICTED: ankyrin repeat (284 aa)
initn: 1778 init1: 1778 opt: 1778 Z-score: 1204.6 bits: 231.0 E(85289): 2.3e-60
Smith-Waterman score: 1778; 100.0% identity (100.0% similar) in 264 aa overlap (66-329:21-284)
40 50 60 70 80 90
pF1KE3 AILSHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYN
::::::::::::::::::::::::::::::
XP_011 MSRIYLDSGWCEVPWGDGDLGSWADRSPLHEAASQGRLLALRTLLSQGYN
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 VNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELL
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE3 LEYGAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYGAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFH
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE3 CIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS
180 190 200 210 220 230
280 290 300 310 320
pF1KE3 SSMVERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSMVERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
240 250 260 270 280
>>NP_543149 (OMIM: 300626) ankyrin repeat and SOCS box p (323 aa)
initn: 1522 init1: 902 opt: 1183 Z-score: 811.1 bits: 158.4 E(85289): 1.9e-38
Smith-Waterman score: 1183; 53.8% identity (81.8% similar) in 325 aa overlap (6-329:2-323)
10 20 30 40 50
pF1KE3 MSVLEENRPFAQQLSNVYFTIL-SLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFY
:. : ..:...:.. ..: :::..:. ::.:.:::::::::::::::: :.:
NP_543 MEDGPVFYGFKNIFITMFATFFFFKLLIKVFLALLTHFYIVKGNRKEAARIAEEIY
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 GVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACA
: . :::::::::::.:::::::.::..:: ::: ::...:. ::::::: :::::
NP_543 GGIS--DCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 RTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKG
..::: ::.::..:. :.::::::: .:: .:...:::.::::::: : :: :::...:
NP_543 KALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 HHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHA
:.::..::.. ....:.:.:.::::::::: :. :. ::: ::.:..:.. ::::::
NP_543 HRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRL
::.::..:...:: ..::... .:.. .:.:. .: ::. :: .:. :. : :::::
NP_543 AARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLREGPPA-LSQLCRL
240 250 260 270 280 290
300 310 320
pF1KE3 CIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
:.:. .:. . : .:.:: :. :: :.
NP_543 CVRKCLGRACHQAIHKLHLPEPLERFLLYQ
300 310 320
>>NP_001012428 (OMIM: 300626) ankyrin repeat and SOCS bo (302 aa)
initn: 1353 init1: 902 opt: 1004 Z-score: 693.2 bits: 136.4 E(85289): 7.2e-32
Smith-Waterman score: 1004; 54.9% identity (83.1% similar) in 266 aa overlap (65-329:38-302)
40 50 60 70 80 90
pF1KE3 LAILSHFYIVKGNRKEAARIAAEFYGVTQGQGS-WADRSPLHEAASQGRLLALRTLLSQG
::. :::::::::::.:::::::.::..::
NP_001 NEKNCEVSERIRRSGPWKEISFGDYICHTFQGDCWADRSPLHEAAAQGRLLALKTLIAQG
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 YNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAE
::: ::...:. ::::::: :::::..::: ::.::..:. :.::::::: .:: .:..
NP_001 VNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHGATPLFNACCSGSAACVN
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE3 LLLEYGAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQ
.:::.::::::: : :: :::...::.::..::.. ....:.:.:.::::::::: :.
NP_001 VLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQR
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE3 FHCIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVA
:. ::: ::.:..:.. ::::::::.::..:...:: ..::... .:.. .:.:
NP_001 VDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLA
190 200 210 220 230 240
280 290 300 310 320
pF1KE3 TSSSMVERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
. .: ::. :: .:. :. : ::::::.:. .:. . : .:.:: :. :: :.
NP_001 APKSSVEQALLLREGPPA-LSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ
250 260 270 280 290 300
>>XP_005274503 (OMIM: 300890) PREDICTED: ankyrin repeat (294 aa)
initn: 820 init1: 820 opt: 906 Z-score: 628.6 bits: 124.5 E(85289): 2.8e-28
Smith-Waterman score: 906; 53.1% identity (79.5% similar) in 258 aa overlap (69-326:35-291)
40 50 60 70 80 90
pF1KE3 SHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNA
.: ::.:::: .:. :.::.:.:::. ::
XP_005 QGGMDGSKPAGPRDFPGIRLLSNPLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNI
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 VTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEY
.: :::.:::::::: :..:.. ::. ::.::..: : ::::::: .:: .:..:::..
XP_005 ITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQH
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE3 GAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIW
::..: :: : :: :::: .:: ::.. ::..: ..:..: :::::::.:: .:: :.
XP_005 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE3 KLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSM
::: .::::..:: :.::::.:. .: :.. ::..:::: .:::.: ::.... :
XP_005 KLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP
190 200 210 220 230 240
280 290 300 310 320
pF1KE3 VERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
. ...:..:. : ::.::::: ::. .: . : : .: :: ::.::
XP_005 LAQLFLEREG-PPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFLLHL
250 260 270 280 290
>>NP_001026909 (OMIM: 300890) ankyrin repeat and SOCS bo (294 aa)
initn: 820 init1: 820 opt: 906 Z-score: 628.6 bits: 124.5 E(85289): 2.8e-28
Smith-Waterman score: 906; 53.1% identity (79.5% similar) in 258 aa overlap (69-326:35-291)
40 50 60 70 80 90
pF1KE3 SHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNA
.: ::.:::: .:. :.::.:.:::. ::
NP_001 QGGMDGSKPAGPRDFPGIRLLSNPLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNI
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 VTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEY
.: :::.:::::::: :..:.. ::. ::.::..: : ::::::: .:: .:..:::..
NP_001 ITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQH
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE3 GAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIW
::..: :: : :: :::: .:: ::.. ::..: ..:..: :::::::.:: .:: :.
NP_001 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE3 KLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSM
::: .::::..:: :.::::.:. .: :.. ::..:::: .:::.: ::.... :
NP_001 KLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP
190 200 210 220 230 240
280 290 300 310 320
pF1KE3 VERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
. ...:..:. : ::.::::: ::. .: . : : .: :: ::.::
NP_001 LAQLFLEREG-PPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFLLHL
250 260 270 280 290
>>XP_016884772 (OMIM: 300890) PREDICTED: ankyrin repeat (377 aa)
initn: 820 init1: 820 opt: 906 Z-score: 627.5 bits: 124.6 E(85289): 3.3e-28
Smith-Waterman score: 906; 53.1% identity (79.5% similar) in 258 aa overlap (69-326:118-374)
40 50 60 70 80 90
pF1KE3 SHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNA
.: ::.:::: .:. :.::.:.:::. ::
XP_016 GKGRDISNFADLGLEGSCGLWRASSQLDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNI
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 VTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEY
.: :::.:::::::: :..:.. ::. ::.::..: : ::::::: .:: .:..:::..
XP_016 ITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQH
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 GAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIW
::..: :: : :: :::: .:: ::.. ::..: ..:..: :::::::.:: .:: :.
XP_016 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 KLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSM
::: .::::..:: :.::::.:. .: :.. ::..:::: .:::.: ::.... :
XP_016 KLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP
270 280 290 300 310 320
280 290 300 310 320
pF1KE3 VERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
. ...:..:. : ::.::::: ::. .: . : : .: :: ::.::
XP_016 LAQLFLEREG-PPSLMQLCRLRIRKCFGIQQHHKITKLVLPEDLKQFLLHL
330 340 350 360 370
>>NP_076992 (OMIM: 300890) ankyrin repeat and SOCS box p (262 aa)
initn: 1243 init1: 800 opt: 806 Z-score: 563.1 bits: 112.2 E(85289): 1.3e-24
Smith-Waterman score: 806; 53.4% identity (81.3% similar) in 219 aa overlap (69-287:35-253)
40 50 60 70 80 90
pF1KE3 SHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNA
.: ::.:::: .:. :.::.:.:::. ::
NP_076 QGGMDGSKPAGPRDFPGIRLLSNPLMGDAVSDWSPMHEAAIHGHQLSLRNLISQGWAVNI
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 VTLDHVTPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEY
.: :::.:::::::: :..:.. ::. ::.::..: : ::::::: .:: .:..:::..
NP_076 ITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQH
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE3 GAKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIW
::..: :: : :: :::: .:: ::.. ::..: ..:..: :::::::.:: .:: :.
NP_076 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE3 KLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSM
::: .::::..:: :.::::.:. .: :.. ::..:::: .:::.: ::.... :
NP_076 KLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP
190 200 210 220 230 240
280 290 300 310 320
pF1KE3 VERILLQHEATPSSLYQLCRLCIRSYIGKPRLHLIPQLQLPTLLKNFLQYR
. ...:..:
NP_076 LAQLFLEREGASLPKPKP
250 260
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:22:28 2016 done: Sun Nov 6 08:22:29 2016
Total Scan time: 6.750 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]