Result of FASTA (omim) for
pFN21AE3970
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3970, 153 aa
1>>>pF1KE3970 153 - 153 aa - 153 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9185+/-0.000268; mu= 15.2450+/- 0.017
mean_var=112.1059+/-23.497, 0's: 0 Z-trim(122.3): 185 B-trim: 2113 in 2/51
Lambda= 0.121132
statistics sampled from 39950 (40339) to 39950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.825), E-opt: 0.2 (0.473), width: 16
Scan time: 3.810
The best scores are: opt bits E(85289)
NP_057578 (OMIM: 612490) E3 ubiquitin-protein liga ( 153) 1085 199.1 2.4e-51
XP_005264416 (OMIM: 612490) PREDICTED: E3 ubiquiti ( 187) 508 98.3 6.1e-21
NP_071763 (OMIM: 300420) E3 ubiquitin-protein liga ( 455) 255 54.6 2.1e-07
NP_001027568 (OMIM: 300420) E3 ubiquitin-protein l ( 588) 255 54.8 2.5e-07
XP_005262349 (OMIM: 300420) PREDICTED: E3 ubiquiti ( 588) 255 54.8 2.5e-07
XP_011529313 (OMIM: 300420) PREDICTED: E3 ubiquiti ( 643) 255 54.8 2.6e-07
NP_660095 (OMIM: 300420) E3 ubiquitin-protein liga ( 643) 255 54.8 2.6e-07
XP_005259651 (OMIM: 615177) PREDICTED: E3 ubiquiti ( 284) 240 51.7 9.8e-07
NP_919442 (OMIM: 615177) E3 ubiquitin-protein liga ( 311) 240 51.8 1e-06
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 195 43.9 0.00024
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 195 43.9 0.00024
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 195 43.9 0.00024
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 195 43.9 0.00024
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 195 44.0 0.00026
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 195 44.0 0.00026
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 195 44.0 0.00026
XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227) 192 43.2 0.00029
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 186 42.1 0.00054
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 186 42.2 0.00063
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 186 42.3 0.00065
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 186 42.5 0.00081
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 186 42.5 0.00081
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 186 42.5 0.00081
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 186 42.5 0.00081
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 186 42.5 0.00081
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 186 42.5 0.00081
XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 180 41.5 0.0017
XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 180 41.5 0.0017
NP_859061 (OMIM: 612063) E3 ubiquitin-protein liga ( 429) 180 41.5 0.0018
NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 180 41.5 0.0018
XP_016869784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
XP_006716784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
NP_919311 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 180 41.5 0.0018
XP_005251423 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
NP_919309 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 180 41.5 0.0018
XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
XP_005251424 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
XP_005251425 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 180 41.5 0.0018
XP_016869783 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 444) 180 41.5 0.0018
>>NP_057578 (OMIM: 612490) E3 ubiquitin-protein ligase R (153 aa)
initn: 1085 init1: 1085 opt: 1085 Z-score: 1042.8 bits: 199.1 E(85289): 2.4e-51
Smith-Waterman score: 1085; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)
10 20 30 40 50 60
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYEL
70 80 90 100 110 120
130 140 150
pF1KE3 PTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:::::::::::::::::::::::::::::::::
NP_057 PTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
130 140 150
>>XP_005264416 (OMIM: 612490) PREDICTED: E3 ubiquitin-pr (187 aa)
initn: 541 init1: 508 opt: 508 Z-score: 496.9 bits: 98.3 E(85289): 6.1e-21
Smith-Waterman score: 508; 96.1% identity (96.1% similar) in 77 aa overlap (1-77:1-77)
10 20 30 40 50 60
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYEL
:::::::::::: : :
XP_005 NLPRTVIRGSQAALTVPWAQYSSFFLFMDCWGMEEEWQLGAGEGGYQLMKIRPRLEHYST
70 80 90 100 110 120
>>NP_071763 (OMIM: 300420) E3 ubiquitin-protein ligase P (455 aa)
initn: 248 init1: 209 opt: 255 Z-score: 253.8 bits: 54.6 E(85289): 2.1e-07
Smith-Waterman score: 255; 32.7% identity (65.5% similar) in 113 aa overlap (14-121:343-452)
10 20 30 40
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRM-DFEDLGL
::. : . .::... . . .:.:..
NP_071 SSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAV
320 330 340 350 360 370
50 60 70 80 90
pF1KE3 VVDWDHHLPPPAAKTVVENLPRTVIRGSQA----ELKCPVCLLEFEEEETAIEMPCHHLF
:. . :::.: .. ::. .. ... :. ::.: :. . :.: :.:::: :
NP_071 DVEVAN---PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYF
380 390 400 410 420
100 110 120 130 140 150
pF1KE3 HSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:. :. ::.:...::.:: .:
NP_071 HKPCVSIWLQKSGTCPVCRCMFPPPL
430 440 450
>>NP_001027568 (OMIM: 300420) E3 ubiquitin-protein ligas (588 aa)
initn: 248 init1: 209 opt: 255 Z-score: 252.7 bits: 54.8 E(85289): 2.5e-07
Smith-Waterman score: 255; 32.7% identity (65.5% similar) in 113 aa overlap (14-121:476-585)
10 20 30 40
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRM-DFEDLGL
::. : . .::... . . .:.:..
NP_001 SSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAV
450 460 470 480 490 500
50 60 70 80 90
pF1KE3 VVDWDHHLPPPAAKTVVENLPRTVIRGSQA----ELKCPVCLLEFEEEETAIEMPCHHLF
:. . :::.: .. ::. .. ... :. ::.: :. . :.: :.:::: :
NP_001 DVEVAN---PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYF
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE3 HSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:. :. ::.:...::.:: .:
NP_001 HKPCVSIWLQKSGTCPVCRCMFPPPL
570 580
>>XP_005262349 (OMIM: 300420) PREDICTED: E3 ubiquitin-pr (588 aa)
initn: 248 init1: 209 opt: 255 Z-score: 252.7 bits: 54.8 E(85289): 2.5e-07
Smith-Waterman score: 255; 32.7% identity (65.5% similar) in 113 aa overlap (14-121:476-585)
10 20 30 40
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRM-DFEDLGL
::. : . .::... . . .:.:..
XP_005 SSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAV
450 460 470 480 490 500
50 60 70 80 90
pF1KE3 VVDWDHHLPPPAAKTVVENLPRTVIRGSQA----ELKCPVCLLEFEEEETAIEMPCHHLF
:. . :::.: .. ::. .. ... :. ::.: :. . :.: :.:::: :
XP_005 DVEVAN---PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYF
510 520 530 540 550 560
100 110 120 130 140 150
pF1KE3 HSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:. :. ::.:...::.:: .:
XP_005 HKPCVSIWLQKSGTCPVCRCMFPPPL
570 580
>>XP_011529313 (OMIM: 300420) PREDICTED: E3 ubiquitin-pr (643 aa)
initn: 248 init1: 209 opt: 255 Z-score: 252.2 bits: 54.8 E(85289): 2.6e-07
Smith-Waterman score: 255; 32.7% identity (65.5% similar) in 113 aa overlap (14-121:531-640)
10 20 30 40
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRM-DFEDLGL
::. : . .::... . . .:.:..
XP_011 SSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAV
510 520 530 540 550 560
50 60 70 80 90
pF1KE3 VVDWDHHLPPPAAKTVVENLPRTVIRGSQA----ELKCPVCLLEFEEEETAIEMPCHHLF
:. . :::.: .. ::. .. ... :. ::.: :. . :.: :.:::: :
XP_011 DVEVAN---PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYF
570 580 590 600 610
100 110 120 130 140 150
pF1KE3 HSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:. :. ::.:...::.:: .:
XP_011 HKPCVSIWLQKSGTCPVCRCMFPPPL
620 630 640
>>NP_660095 (OMIM: 300420) E3 ubiquitin-protein ligase P (643 aa)
initn: 248 init1: 209 opt: 255 Z-score: 252.2 bits: 54.8 E(85289): 2.6e-07
Smith-Waterman score: 255; 32.7% identity (65.5% similar) in 113 aa overlap (14-121:531-640)
10 20 30 40
pF1KE3 MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRM-DFEDLGL
::. : . .::... . . .:.:..
NP_660 SSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAV
510 520 530 540 550 560
50 60 70 80 90
pF1KE3 VVDWDHHLPPPAAKTVVENLPRTVIRGSQA----ELKCPVCLLEFEEEETAIEMPCHHLF
:. . :::.: .. ::. .. ... :. ::.: :. . :.: :.:::: :
NP_660 DVEVAN---PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYF
570 580 590 600 610
100 110 120 130 140 150
pF1KE3 HSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
:. :. ::.:...::.:: .:
NP_660 HKPCVSIWLQKSGTCPVCRCMFPPPL
620 630 640
>>XP_005259651 (OMIM: 615177) PREDICTED: E3 ubiquitin-pr (284 aa)
initn: 238 init1: 197 opt: 240 Z-score: 241.9 bits: 51.7 E(85289): 9.8e-07
Smith-Waterman score: 240; 36.7% identity (64.4% similar) in 90 aa overlap (33-120:157-246)
10 20 30 40 50 60
pF1KE3 SYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVENL
: .: :. .... :::: : .. :
XP_005 VNGIITPATIPSLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENTGPPPADKEKIQAL
130 140 150 160 170 180
70 80 90 100 110 120
pF1KE3 PRTVIRGSQ--AELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYEL
: . . . . :.:::: .. : . ..::.::::..::.::: . .:::.:: :
XP_005 PTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSL
190 200 210 220 230 240
130 140 150
pF1KE3 PTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
XP_005 TGQNTATNPPGLTGVSFSSSSSSSSSSSPSNENATSNS
250 260 270 280
>>NP_919442 (OMIM: 615177) E3 ubiquitin-protein ligase R (311 aa)
initn: 238 init1: 197 opt: 240 Z-score: 241.4 bits: 51.8 E(85289): 1e-06
Smith-Waterman score: 240; 36.7% identity (64.4% similar) in 90 aa overlap (33-120:184-273)
10 20 30 40 50 60
pF1KE3 SYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVENL
: .: :. .... :::: : .. :
NP_919 VNGIITPATIPSLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENTGPPPADKEKIQAL
160 170 180 190 200 210
70 80 90 100 110 120
pF1KE3 PRTVIRGSQ--AELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYEL
: . . . . :.:::: .. : . ..::.::::..::.::: . .:::.:: :
NP_919 PTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSL
220 230 240 250 260 270
130 140 150
pF1KE3 PTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
NP_919 TGQNTATNPPGLTGVSFSSSSSSSSSSSPSNENATSNS
280 290 300 310
>>NP_001307292 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 165 init1: 123 opt: 195 Z-score: 198.9 bits: 43.9 E(85289): 0.00024
Smith-Waterman score: 195; 37.9% identity (66.7% similar) in 66 aa overlap (68-129:188-252)
40 50 60 70 80 90
pF1KE3 EDLGLVVDWDHHLPPPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHL
.:.: .. : .:: :.:. . .:: :
NP_001 IARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDV-CAICLDEYEDGDKLRVLPCAHA
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE3 FHSSCILPWLSKT-NSCPLCRYEL---PTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
.:: :. :::..: ..::.:. . : :.: ::
NP_001 YHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHPASERTPLL
220 230 240 250 260 270
NP_001 GSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
280 290 300 310
153 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:27:51 2016 done: Sun Nov 6 08:27:51 2016
Total Scan time: 3.810 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]