Result of FASTA (omim) for
pFN21AE3968
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3968, 405 aa
1>>>pF1KE3968 405 - 405 aa - 405 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0588+/-0.000409; mu= 9.1274+/- 0.026
mean_var=124.0206+/-24.602, 0's: 0 Z-trim(115.1): 53 B-trim: 33 in 1/48
Lambda= 0.115167
statistics sampled from 25216 (25269) to 25216 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.296), width: 16
Scan time: 7.390
The best scores are: opt bits E(85289)
NP_006686 (OMIM: 605448) RUN domain-containing pro ( 405) 2641 450.2 4.3e-126
NP_001138297 (OMIM: 605448) RUN domain-containing ( 446) 2608 444.7 2.1e-124
XP_016879527 (OMIM: 605448) PREDICTED: RUN domain- ( 434) 2603 443.9 3.6e-124
XP_016879528 (OMIM: 605448) PREDICTED: RUN domain- ( 433) 2600 443.4 5.1e-124
XP_016879524 (OMIM: 605448) PREDICTED: RUN domain- ( 474) 2600 443.4 5.5e-124
XP_016879529 (OMIM: 605448) PREDICTED: RUN domain- ( 401) 2590 441.7 1.5e-123
NP_001138298 (OMIM: 605448) RUN domain-containing ( 400) 2583 440.5 3.4e-123
XP_005257021 (OMIM: 605448) PREDICTED: RUN domain- ( 441) 2550 435.1 1.6e-121
XP_016879525 (OMIM: 605448) PREDICTED: RUN domain- ( 470) 2549 434.9 1.9e-121
XP_016879526 (OMIM: 605448) PREDICTED: RUN domain- ( 469) 2542 433.7 4.3e-121
NP_001124181 (OMIM: 611194) protein RUFY3 isoform ( 506) 365 72.1 3.6e-12
XP_011530058 (OMIM: 611194) PREDICTED: protein RUF ( 518) 365 72.1 3.6e-12
XP_011530057 (OMIM: 611194) PREDICTED: protein RUF ( 529) 365 72.1 3.7e-12
XP_011530056 (OMIM: 611194) PREDICTED: protein RUF ( 586) 365 72.1 4e-12
XP_016863379 (OMIM: 611194) PREDICTED: protein RUF ( 587) 365 72.1 4e-12
XP_011530055 (OMIM: 611194) PREDICTED: protein RUF ( 621) 365 72.1 4.2e-12
XP_011530054 (OMIM: 611194) PREDICTED: protein RUF ( 621) 365 72.1 4.2e-12
XP_011530053 (OMIM: 611194) PREDICTED: protein RUF ( 657) 365 72.1 4.4e-12
XP_011530052 (OMIM: 611194) PREDICTED: protein RUF ( 680) 365 72.1 4.5e-12
XP_016863381 (OMIM: 611194) PREDICTED: protein RUF ( 405) 361 71.3 4.7e-12
NP_001332769 (OMIM: 611194) protein RUFY3 isoform ( 416) 361 71.3 4.8e-12
NP_055776 (OMIM: 611194) protein RUFY3 isoform 2 [ ( 469) 361 71.4 5.3e-12
NP_001278923 (OMIM: 611194) protein RUFY3 isoform ( 487) 361 71.4 5.5e-12
XP_006714984 (OMIM: 610327) PREDICTED: RUN and FYV ( 686) 363 71.8 5.7e-12
XP_005265715 (OMIM: 611194) PREDICTED: protein RUF ( 556) 361 71.4 6.1e-12
NP_001278922 (OMIM: 611194) protein RUFY3 isoform ( 567) 361 71.4 6.2e-12
NP_001032519 (OMIM: 611194) protein RUFY3 isoform ( 620) 361 71.4 6.6e-12
XP_005265713 (OMIM: 611194) PREDICTED: protein RUF ( 638) 361 71.5 6.8e-12
XP_016865380 (OMIM: 610327) PREDICTED: RUN and FYV ( 578) 355 70.4 1.3e-11
XP_005270013 (OMIM: 610328) PREDICTED: RUN and FYV ( 585) 352 69.9 1.8e-11
NP_079434 (OMIM: 610327) RUN and FYVE domain-conta ( 708) 340 68.0 8.3e-11
NP_060457 (OMIM: 610328) RUN and FYVE domain-conta ( 641) 339 67.8 8.6e-11
XP_011538244 (OMIM: 610328) PREDICTED: RUN and FYV ( 606) 337 67.5 1e-10
NP_001317032 (OMIM: 610328) RUN and FYVE domain-co ( 606) 337 67.5 1e-10
NP_001035542 (OMIM: 610327) RUN and FYVE domain-co ( 600) 332 66.6 1.8e-10
NP_001035541 (OMIM: 610327) RUN and FYVE domain-co ( 600) 332 66.6 1.8e-10
XP_005270012 (OMIM: 610328) PREDICTED: RUN and FYV ( 590) 298 61.0 9e-09
NP_001265154 (OMIM: 610328) RUN and FYVE domain-co ( 379) 272 56.5 1.3e-07
NP_078789 (OMIM: 607182,610019) FYVE and coiled-co (1478) 219 48.1 0.00017
XP_006713396 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 219 48.1 0.00017
XP_006713397 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 219 48.1 0.00017
XP_011532413 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 219 48.1 0.00017
NP_001035882 (OMIM: 610328) RUN and FYVE domain-co ( 403) 203 45.1 0.00037
XP_005270014 (OMIM: 610328) PREDICTED: RUN and FYV ( 572) 203 45.2 0.0005
XP_005270010 (OMIM: 610328) PREDICTED: RUN and FYV ( 607) 203 45.2 0.00052
>>NP_006686 (OMIM: 605448) RUN domain-containing protein (405 aa)
initn: 2641 init1: 2641 opt: 2641 Z-score: 2384.7 bits: 450.2 E(85289): 4.3e-126
Smith-Waterman score: 2641; 100.0% identity (100.0% similar) in 405 aa overlap (1-405:1-405)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
310 320 330 340 350 360
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::::::::
NP_006 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
370 380 390 400
>>NP_001138297 (OMIM: 605448) RUN domain-containing prot (446 aa)
initn: 2608 init1: 2608 opt: 2608 Z-score: 2354.5 bits: 444.7 E(85289): 2.1e-124
Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
310 320 330 340 350 360
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
::::::::::::::::::::::::::::::::::::::::
NP_001 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGKDPTPSMLGLCGSLASIPSC
370 380 390 400 410 420
NP_001 KSLASFKSNECLVSDSPEGSPALSPS
430 440
>>XP_016879527 (OMIM: 605448) PREDICTED: RUN domain-cont (434 aa)
initn: 2600 init1: 2600 opt: 2603 Z-score: 2350.2 bits: 443.9 E(85289): 3.6e-124
Smith-Waterman score: 2603; 99.3% identity (99.5% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
310 320 330 340 350 360
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
::::::::::::::::::::::::::::::::::::::: .:
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIVETEFRQAGLELLTSSDSPTL
370 380 390 400 410 420
XP_016 ASQSAGITGSSEPN
430
>>XP_016879528 (OMIM: 605448) PREDICTED: RUN domain-cont (433 aa)
initn: 2600 init1: 2600 opt: 2600 Z-score: 2347.5 bits: 443.4 E(85289): 5.1e-124
Smith-Waterman score: 2600; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
310 320 330 340 350 360
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIETEFRQAGLELLTSSDSPTLA
370 380 390 400 410 420
XP_016 SQSAGITGSSEPN
430
>>XP_016879524 (OMIM: 605448) PREDICTED: RUN domain-cont (474 aa)
initn: 2600 init1: 2600 opt: 2600 Z-score: 2346.9 bits: 443.4 E(85289): 5.5e-124
Smith-Waterman score: 2600; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
310 320 330 340 350 360
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIETEFRQAGLELLTSSDSPTLA
370 380 390 400 410 420
XP_016 SQSAGITGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS
430 440 450 460 470
>>XP_016879529 (OMIM: 605448) PREDICTED: RUN domain-cont (401 aa)
initn: 2158 init1: 2158 opt: 2590 Z-score: 2339.0 bits: 441.7 E(85289): 1.5e-123
Smith-Waterman score: 2590; 99.0% identity (99.0% similar) in 405 aa overlap (1-405:1-401)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFKA----GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
300 310 320 330 340 350
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
360 370 380 390 400
>>NP_001138298 (OMIM: 605448) RUN domain-containing prot (400 aa)
initn: 2589 init1: 2153 opt: 2583 Z-score: 2332.7 bits: 440.5 E(85289): 3.4e-123
Smith-Waterman score: 2583; 98.8% identity (98.8% similar) in 405 aa overlap (1-405:1-400)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 FAAILEQILSHRFK-----GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
300 310 320 330 340 350
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
360 370 380 390 400
>>XP_005257021 (OMIM: 605448) PREDICTED: RUN domain-cont (441 aa)
initn: 2556 init1: 2120 opt: 2550 Z-score: 2302.5 bits: 435.1 E(85289): 1.6e-121
Smith-Waterman score: 2550; 98.8% identity (98.8% similar) in 400 aa overlap (1-400:1-395)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 FAAILEQILSHRFK-----GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
300 310 320 330 340 350
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
::::::::::::::::::::::::::::::::::::::::
XP_005 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGKDPTPSMLGLCGSLASIPSC
360 370 380 390 400 410
XP_005 KSLASFKSNECLVSDSPEGSPALSPS
420 430 440
>>XP_016879525 (OMIM: 605448) PREDICTED: RUN domain-cont (470 aa)
initn: 2117 init1: 2117 opt: 2549 Z-score: 2301.2 bits: 434.9 E(85289): 1.9e-121
Smith-Waterman score: 2549; 99.0% identity (99.0% similar) in 399 aa overlap (1-399:1-395)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFKA----GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
300 310 320 330 340 350
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIETEFRQAGLELLTSSDSPTLA
360 370 380 390 400 410
XP_016 SQSAGITGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS
420 430 440 450 460 470
>>XP_016879526 (OMIM: 605448) PREDICTED: RUN domain-cont (469 aa)
initn: 2548 init1: 2112 opt: 2542 Z-score: 2294.9 bits: 433.7 E(85289): 4.3e-121
Smith-Waterman score: 2542; 98.7% identity (98.7% similar) in 399 aa overlap (1-399:1-394)
10 20 30 40 50 60
pF1KE3 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 FAAILEQILSHRFK-----GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSK
300 310 320 330 340 350
370 380 390 400
pF1KE3 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGSSEPN
:::::::::::::::::::::::::::::::::::::::
XP_016 LYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIETEFRQAGLELLTSSDSPTLA
360 370 380 390 400 410
XP_016 SQSAGITGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS
420 430 440 450 460
405 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:16:32 2016 done: Mon Nov 7 19:16:33 2016
Total Scan time: 7.390 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]