Result of FASTA (omim) for
pFN21AE3960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3960, 562 aa
1>>>pF1KE3960 562 - 562 aa - 562 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3554+/-0.000406; mu= 15.8257+/- 0.025
mean_var=152.8220+/-30.703, 0's: 0 Z-trim(116.7): 140 B-trim: 170 in 2/53
Lambda= 0.103748
statistics sampled from 27809 (28006) to 27809 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.328), width: 16
Scan time: 8.220
The best scores are: opt bits E(85289)
NP_001139107 (OMIM: 609318) tripartite motif-conta ( 562) 3893 595.0 2.1e-169
NP_079464 (OMIM: 609318) tripartite motif-containi ( 580) 2646 408.4 3.2e-113
XP_011540501 (OMIM: 609318) PREDICTED: tripartite ( 476) 1943 303.1 1.3e-81
NP_003843 (OMIM: 188550,603406) transcription inte (1016) 495 86.7 3.9e-16
NP_056989 (OMIM: 188550,603406) transcription inte (1050) 495 86.7 4e-16
XP_016856943 (OMIM: 188550,605769) PREDICTED: E3 u ( 638) 443 78.7 6.3e-14
NP_148980 (OMIM: 188550,605769) E3 ubiquitin-prote (1110) 443 79.0 9.1e-14
NP_056990 (OMIM: 188550,605769) E3 ubiquitin-prote (1127) 443 79.0 9.2e-14
XP_005270994 (OMIM: 188550,605769) PREDICTED: E3 u (1134) 443 79.0 9.2e-14
XP_011539870 (OMIM: 188550,605769) PREDICTED: E3 u (1150) 443 79.0 9.3e-14
XP_005270993 (OMIM: 188550,605769) PREDICTED: E3 u (1151) 443 79.0 9.3e-14
XP_011518146 (OMIM: 605493) PREDICTED: tripartite ( 744) 363 66.8 2.8e-10
NP_006449 (OMIM: 605493) tripartite motif-containi ( 744) 363 66.8 2.8e-10
NP_150594 (OMIM: 605493) tripartite motif-containi ( 744) 363 66.8 2.8e-10
XP_016872587 (OMIM: 605493) PREDICTED: tripartite ( 744) 363 66.8 2.8e-10
NP_001234935 (OMIM: 605493) tripartite motif-conta ( 744) 363 66.8 2.8e-10
XP_016863436 (OMIM: 614141,615490) PREDICTED: trip ( 761) 341 63.5 2.8e-09
XP_016863435 (OMIM: 614141,615490) PREDICTED: trip ( 762) 341 63.5 2.8e-09
XP_011530096 (OMIM: 614141,615490) PREDICTED: trip ( 765) 341 63.5 2.8e-09
XP_006714222 (OMIM: 614141,615490) PREDICTED: trip ( 766) 341 63.5 2.8e-09
XP_016863432 (OMIM: 614141,615490) PREDICTED: trip ( 770) 341 63.5 2.8e-09
NP_056086 (OMIM: 614141,615490) tripartite motif-c ( 771) 341 63.5 2.8e-09
XP_006714221 (OMIM: 614141,615490) PREDICTED: trip ( 774) 341 63.5 2.8e-09
XP_006714220 (OMIM: 614141,615490) PREDICTED: trip ( 775) 341 63.5 2.8e-09
XP_016863433 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863439 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863440 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863437 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863441 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863434 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
XP_016863438 (OMIM: 614141,615490) PREDICTED: trip ( 744) 339 63.2 3.4e-09
NP_001123539 (OMIM: 614141,615490) tripartite moti ( 744) 339 63.2 3.4e-09
XP_006714223 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
XP_006714225 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
XP_006714224 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
XP_011530097 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
XP_011530098 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
XP_011530100 (OMIM: 614141,615490) PREDICTED: trip ( 748) 339 63.2 3.4e-09
NP_112223 (OMIM: 616996) E3 ubiquitin-protein liga ( 755) 339 63.2 3.4e-09
XP_011514891 (OMIM: 616996) PREDICTED: E3 ubiquiti ( 755) 339 63.2 3.4e-09
NP_005753 (OMIM: 601742) transcription intermediar ( 835) 301 57.6 1.9e-07
XP_016865112 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 529) 297 56.7 2.1e-07
NP_001287688 (OMIM: 609317) E3 ubiquitin-protein l ( 716) 297 56.9 2.6e-07
NP_061170 (OMIM: 609317) E3 ubiquitin-protein liga ( 728) 297 56.9 2.6e-07
XP_016865111 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 733) 297 56.9 2.6e-07
XP_016865110 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 745) 297 56.9 2.6e-07
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 288 55.4 5.1e-07
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 288 55.4 5.1e-07
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 288 55.4 5.5e-07
XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685) 289 55.7 5.7e-07
>>NP_001139107 (OMIM: 609318) tripartite motif-containin (562 aa)
initn: 3893 init1: 3893 opt: 3893 Z-score: 3162.5 bits: 595.0 E(85289): 2.1e-169
Smith-Waterman score: 3893; 99.5% identity (99.5% similar) in 562 aa overlap (1-562:1-562)
10 20 30 40 50 60
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 VQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 VQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNE
490 500 510 520 530 540
550 560
pF1KE3 KSECTWTGGQSAPRSLLRTVAL
::::::::::::::::::::::
NP_001 KSECTWTGGQSAPRSLLRTVAL
550 560
>>NP_079464 (OMIM: 609318) tripartite motif-containing p (580 aa)
initn: 2675 init1: 2644 opt: 2646 Z-score: 2153.6 bits: 408.4 E(85289): 3.2e-113
Smith-Waterman score: 3847; 96.4% identity (96.4% similar) in 580 aa overlap (1-562:1-580)
10 20 30 40 50 60
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKV
310 320 330 340 350 360
370 380 390 400
pF1KE3 QYSTRPGVNDKIRFCPQEKAGQCRGYEIY------------------DLHRAREKQTASF
::::::::::::::::::::::::::::: :::::::::::::
NP_079 QYSTRPGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASF
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 TLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVW
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 VCIKEQHVQGSPFTVTVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHG
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_079 VCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHG
490 500 510 520 530 540
530 540 550 560
pF1KE3 HKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL
::::::::::::::::::::::::::::::::::::::::
NP_079 HKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL
550 560 570 580
>>XP_011540501 (OMIM: 609318) PREDICTED: tripartite moti (476 aa)
initn: 1972 init1: 1941 opt: 1943 Z-score: 1585.9 bits: 303.1 E(85289): 1.3e-81
Smith-Waterman score: 3144; 95.8% identity (95.8% similar) in 476 aa overlap (105-562:1-476)
80 90 100 110 120 130
pF1KE3 GSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLV
::::::::::::::::::::::::::::::
XP_011 MGGVKALTIDHLAVNDVMLESLRGEGQGLV
10 20 30
140 150 160 170 180 190
pF1KE3 CDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVH
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 PAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKDTQPHVEALEE
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 PAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 ALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE3 AQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF
220 230 240 250 260 270
380 390 400 410
pF1KE3 CPQEKAGQCRGYEIY------------------DLHRAREKQTASFTLLCKDAAGEIMGR
::::::::::::::: :::::::::::::::::::::::::::
XP_011 CPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASFTLLCKDAAGEIMGR
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE3 GGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFT
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE3 VTVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCG
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCG
400 410 420 430 440 450
540 550 560
pF1KE3 KFNEKSECTWTGGQSAPRSLLRTVAL
::::::::::::::::::::::::::
XP_011 KFNEKSECTWTGGQSAPRSLLRTVAL
460 470
>>NP_003843 (OMIM: 188550,603406) transcription intermed (1016 aa)
initn: 410 init1: 297 opt: 495 Z-score: 410.7 bits: 86.7 E(85289): 3.9e-16
Smith-Waterman score: 495; 27.9% identity (58.3% similar) in 369 aa overlap (29-375:56-408)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLF--KAPRLLPCLHTVCTTCLEQL
: .: . .::.::::::. : ::
NP_003 APSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAP
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 EPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIGIL-CPVCDAQVDLPMGGVKA
. . .. :...: . :: . .: . .:.:.. ::::. . ..
NP_003 QRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVGVIRCPVCSQEC------AER
90 100 110 120 130
120 130 140 150 160
pF1KE3 LTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKANLCHFCCQAHRRQKKT
::.. :.:. . : : .. :: :.: :.. : : ::. : .::.: : :
NP_003 HIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 TYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPC
:: : :. . .: .:..:: : :.:.:.:: ::. .:.:: . ::.::
NP_003 KDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRY
200 210 220 230 240 250
230 240 250 260 270
pF1KE3 DFTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRV-------EAVAADV
.: ...... ... :: . : : :.. .. .:.:. . : :.
NP_003 QFIEEAFQNQ-----KVIIDTL--ITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDI
260 270 280 290 300
280 290 300 310 320 330
pF1KE3 RTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTS
.. . :... ::.:::.. ... .:. :. .. : ... ..:.. ..:
NP_003 KVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 GSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRARE
::. .: .::... :::.: ... .. : .:. :.: :
NP_003 GSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINLGSLVIEDKE
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 KQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEP
NP_003 SQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPPRLINFQNHS
430 440 450 460 470 480
>>NP_056989 (OMIM: 188550,603406) transcription intermed (1050 aa)
initn: 392 init1: 279 opt: 495 Z-score: 410.5 bits: 86.7 E(85289): 4e-16
Smith-Waterman score: 495; 27.9% identity (58.3% similar) in 369 aa overlap (29-375:56-408)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLF--KAPRLLPCLHTVCTTCLEQL
: .: . .::.::::::. : ::
NP_056 APSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAP
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 EPFSVVDIRG-GDSDTS----SEGSIFQELKPRSLQSQIGIL-CPVCDAQVDLPMGGVKA
. . .. :...: . :: . .: . .:.:.. ::::. . ..
NP_056 QRYLMLPAPMLGSAETPPPVPAPGSPVSGSSP--FATQVGVIRCPVCSQEC------AER
90 100 110 120 130
120 130 140 150 160
pF1KE3 LTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKANLCHFCCQAHRRQKKT
::.. :.:. . : : .. :: :.: :.. : : ::. : .::.: : :
NP_056 HIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 TYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPC
:: : :. . .: .:..:: : :.:.:.:: ::. .:.:: . ::.::
NP_056 KDHT-VRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRY
200 210 220 230 240 250
230 240 250 260 270
pF1KE3 DFTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRV-------EAVAADV
.: ...... ... :: . : : :.. .. .:.:. . : :.
NP_056 QFIEEAFQNQ-----KVIIDTL--ITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDI
260 270 280 290 300
280 290 300 310 320 330
pF1KE3 RTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTS
.. . :... ::.:::.. ... .:. :. .. : ... ..:.. ..:
NP_056 KVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 GSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRARE
::. .: .::... :::.: ... .. : .:. :.: :
NP_056 GSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINLGSLVIEDKE
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 KQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEP
NP_056 SQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQRQQVQRRPA
430 440 450 460 470 480
>>XP_016856943 (OMIM: 188550,605769) PREDICTED: E3 ubiqu (638 aa)
initn: 454 init1: 334 opt: 443 Z-score: 371.0 bits: 78.7 E(85289): 6.3e-14
Smith-Waterman score: 518; 29.1% identity (57.1% similar) in 361 aa overlap (29-375:125-461)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKA-----PRLLPCLHTVCTTCL
: .: ... :.::::::. : ::
XP_016 STPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL
100 110 120 130 140 150
60 70 80 90 100
pF1KE3 EQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVCDA---QVDLPMGGVK
. : : : :: :.:.: .:.:.. :::: :.::
XP_016 PEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVCRQECRQIDL------
160 170 180 190
110 120 130 140 150 160
pF1KE3 ALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDREVE-KRCQTCKANLCHFCCQAHRRQKK
.:. :.:. : : . :: :.: : : ::. : .::.: :
XP_016 ---VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE3 TTYHTMVDLKDL-KGYSRIG-KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCD
: : . .:. .. . : .:..:::: :.:.:::: ::: .:.:: . ::.:: .
XP_016 TKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQ
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE3 FTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYI
: ...... .. .:: . . .. : .:.. . ... . : .... :
XP_016 FLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLI
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE3 KAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILI
. :... .::.:::.. ... .: :. .. : ... ..::. ..:::. .:
XP_016 NEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE3 TKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRAREKQTASFTL
.::... .::.. :.. . :..: ::: :
XP_016 SKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNV
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE3 LCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVC
XP_016 VVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTT
500 510 520 530 540 550
>>NP_148980 (OMIM: 188550,605769) E3 ubiquitin-protein l (1110 aa)
initn: 454 init1: 334 opt: 443 Z-score: 368.2 bits: 79.0 E(85289): 9.1e-14
Smith-Waterman score: 518; 29.1% identity (57.1% similar) in 361 aa overlap (29-375:125-461)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKA-----PRLLPCLHTVCTTCL
: .: ... :.::::::. : ::
NP_148 STPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL
100 110 120 130 140 150
60 70 80 90 100
pF1KE3 EQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVCDA---QVDLPMGGVK
. : : : :: :.:.: .:.:.. :::: :.::
NP_148 PEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVCRQECRQIDL------
160 170 180 190
110 120 130 140 150 160
pF1KE3 ALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDREVE-KRCQTCKANLCHFCCQAHRRQKK
.:. :.:. : : . :: :.: : : ::. : .::.: :
NP_148 ---VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE3 TTYHTMVDLKDL-KGYSRIG-KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCD
: : . .:. .. . : .:..:::: :.:.:::: ::: .:.:: . ::.:: .
NP_148 TKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQ
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE3 FTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYI
: ...... .. .:: . . .. : .:.. . ... . : .... :
NP_148 FLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLI
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE3 KAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILI
. :... .::.:::.. ... .: :. .. : ... ..::. ..:::. .:
NP_148 NEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE3 TKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRAREKQTASFTL
.::... .::.. :.. . :..: ::: :
NP_148 SKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNV
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE3 LCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVC
NP_148 VVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTT
500 510 520 530 540 550
>>NP_056990 (OMIM: 188550,605769) E3 ubiquitin-protein l (1127 aa)
initn: 454 init1: 334 opt: 443 Z-score: 368.1 bits: 79.0 E(85289): 9.2e-14
Smith-Waterman score: 518; 29.1% identity (57.1% similar) in 361 aa overlap (29-375:125-461)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKA-----PRLLPCLHTVCTTCL
: .: ... :.::::::. : ::
NP_056 STPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL
100 110 120 130 140 150
60 70 80 90 100
pF1KE3 EQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVCDA---QVDLPMGGVK
. : : : :: :.:.: .:.:.. :::: :.::
NP_056 PEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVCRQECRQIDL------
160 170 180 190
110 120 130 140 150 160
pF1KE3 ALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDREVE-KRCQTCKANLCHFCCQAHRRQKK
.:. :.:. : : . :: :.: : : ::. : .::.: :
NP_056 ---VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE3 TTYHTMVDLKDL-KGYSRIG-KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCD
: : . .:. .. . : .:..:::: :.:.:::: ::: .:.:: . ::.:: .
NP_056 TKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQ
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE3 FTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYI
: ...... .. .:: . . .. : .:.. . ... . : .... :
NP_056 FLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLI
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE3 KAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILI
. :... .::.:::.. ... .: :. .. : ... ..::. ..:::. .:
NP_056 NEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE3 TKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRAREKQTASFTL
.::... .::.. :.. . :..: ::: :
NP_056 SKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNV
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE3 LCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVC
NP_056 VVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTT
500 510 520 530 540 550
>>XP_005270994 (OMIM: 188550,605769) PREDICTED: E3 ubiqu (1134 aa)
initn: 454 init1: 334 opt: 443 Z-score: 368.1 bits: 79.0 E(85289): 9.2e-14
Smith-Waterman score: 518; 29.1% identity (57.1% similar) in 361 aa overlap (29-375:125-461)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKA-----PRLLPCLHTVCTTCL
: .: ... :.::::::. : ::
XP_005 STPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL
100 110 120 130 140 150
60 70 80 90 100
pF1KE3 EQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVCDA---QVDLPMGGVK
. : : : :: :.:.: .:.:.. :::: :.::
XP_005 PEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVCRQECRQIDL------
160 170 180 190
110 120 130 140 150 160
pF1KE3 ALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDREVE-KRCQTCKANLCHFCCQAHRRQKK
.:. :.:. : : . :: :.: : : ::. : .::.: :
XP_005 ---VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE3 TTYHTMVDLKDL-KGYSRIG-KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCD
: : . .:. .. . : .:..:::: :.:.:::: ::: .:.:: . ::.:: .
XP_005 TKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQ
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE3 FTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYI
: ...... .. .:: . . .. : .:.. . ... . : .... :
XP_005 FLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLI
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE3 KAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILI
. :... .::.:::.. ... .: :. .. : ... ..::. ..:::. .:
XP_005 NEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE3 TKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRAREKQTASFTL
.::... .::.. :.. . :..: ::: :
XP_005 SKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNV
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE3 LCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVC
XP_005 VVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTT
500 510 520 530 540 550
>>XP_011539870 (OMIM: 188550,605769) PREDICTED: E3 ubiqu (1150 aa)
initn: 454 init1: 334 opt: 443 Z-score: 368.0 bits: 79.0 E(85289): 9.3e-14
Smith-Waterman score: 518; 29.1% identity (57.1% similar) in 361 aa overlap (29-375:125-461)
10 20 30 40 50
pF1KE3 MSENRKTLLGFVSKLTSGTALGNSGKTHCPLCLGLFKA-----PRLLPCLHTVCTTCL
: .: ... :.::::::. : ::
XP_011 STPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL
100 110 120 130 140 150
60 70 80 90 100
pF1KE3 EQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVCDA---QVDLPMGGVK
. : : : :: :.:.: .:.:.. :::: :.::
XP_011 PEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVCRQECRQIDL------
160 170 180 190
110 120 130 140 150 160
pF1KE3 ALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDREVE-KRCQTCKANLCHFCCQAHRRQKK
.:. :.:. : : . :: :.: : : ::. : .::.: :
XP_011 ---VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE3 TTYHTMVDLKDL-KGYSRIG-KPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCD
: : . .:. .. . : .:..:::: :.:.:::: ::: .:.:: . ::.:: .
XP_011 TKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQ
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE3 FTSNVIHKHGDSVWELLKDTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYI
: ...... .. .:: . . .. : .:.. . ... . : .... :
XP_011 FLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLI
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE3 KAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILI
. :... .::.:::.. ... .: :. .. : ... ..::. ..:::. .:
XP_011 NEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLY
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE3 TKRVVVERLRKLNKVQYSTRPGVNDKIRF-CPQEKAGQCRGYEIYDLHRAREKQTASFTL
.::... .::.. :.. . :..: ::: :
XP_011 SKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNV
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE3 LCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVC
XP_011 VVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTT
500 510 520 530 540 550
562 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:33:56 2016 done: Sun Nov 6 08:33:57 2016
Total Scan time: 8.220 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]