Result of FASTA (omim) for
pFN21AE3957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3957, 341 aa
1>>>pF1KE3957 341 - 341 aa - 341 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7270+/-0.000398; mu= 3.8750+/- 0.025
mean_var=128.0869+/-25.532, 0's: 0 Z-trim(115.2): 196 B-trim: 357 in 1/56
Lambda= 0.113324
statistics sampled from 25345 (25542) to 25345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.299), width: 16
Scan time: 7.170
The best scores are: opt bits E(85289)
NP_542783 (OMIM: 616017) E3 ubiquitin-protein liga ( 341) 2267 382.0 9.8e-106
NP_892030 (OMIM: 616017) E3 ubiquitin-protein liga ( 500) 2254 380.0 6e-105
NP_001288073 (OMIM: 616017) E3 ubiquitin-protein l ( 296) 1989 336.6 4.2e-92
NP_001288075 (OMIM: 616017) E3 ubiquitin-protein l ( 263) 1583 270.2 3.6e-72
NP_001288074 (OMIM: 616017) E3 ubiquitin-protein l ( 279) 1577 269.2 7.5e-72
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 663 119.9 1.2e-26
NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 635 115.3 2.7e-25
XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 635 115.3 3.1e-25
NP_001317412 (OMIM: 616755) E3 ubiquitin-protein l ( 354) 630 114.4 3.7e-25
XP_016857119 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 544) 607 110.7 7.4e-24
NP_001017922 (OMIM: 111620,111750,609017) erythroi ( 475) 586 107.3 7.1e-23
XP_006710376 (OMIM: 111620,111750,609017) PREDICTE ( 475) 586 107.3 7.1e-23
NP_061008 (OMIM: 111620,111750,609017) erythroid m ( 475) 586 107.3 7.1e-23
XP_011538872 (OMIM: 111620,111750,609017) PREDICTE ( 475) 586 107.3 7.1e-23
XP_011538873 (OMIM: 111620,111750,609017) PREDICTE ( 468) 573 105.1 3.1e-22
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 568 104.3 5.9e-22
NP_835226 (OMIM: 612548) E3 ubiquitin-protein liga ( 487) 538 99.4 1.7e-20
NP_001268380 (OMIM: 612548) E3 ubiquitin-protein l ( 487) 538 99.4 1.7e-20
NP_001268379 (OMIM: 612548) E3 ubiquitin-protein l ( 486) 537 99.3 1.9e-20
XP_011514091 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 486) 537 99.3 1.9e-20
NP_976038 (OMIM: 609315) tripartite motif-containi ( 511) 536 99.1 2.2e-20
NP_976041 (OMIM: 609315) tripartite motif-containi ( 303) 527 97.5 3.8e-20
NP_976040 (OMIM: 609315) tripartite motif-containi ( 303) 527 97.5 3.8e-20
NP_976039 (OMIM: 609315) tripartite motif-containi ( 303) 527 97.5 3.8e-20
XP_016865392 (OMIM: 609315) PREDICTED: tripartite ( 303) 527 97.5 3.8e-20
NP_976042 (OMIM: 609315) tripartite motif-containi ( 329) 527 97.6 4.1e-20
XP_011514090 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 278) 509 94.6 2.7e-19
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780) 504 93.9 1.2e-18
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781) 504 93.9 1.2e-18
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 499 93.1 1.5e-18
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 498 92.9 1.5e-18
NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 480 90.0 1.3e-17
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 480 90.0 1.5e-17
XP_006715046 (OMIM: 613593) PREDICTED: butyrophili ( 419) 475 89.1 1.8e-17
NP_001138480 (OMIM: 613593) butyrophilin subfamily ( 461) 475 89.1 2e-17
NP_008979 (OMIM: 613593) butyrophilin subfamily 3 ( 513) 475 89.1 2.2e-17
NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 471 88.4 2.2e-17
XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 471 88.4 2.2e-17
NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 471 88.4 2.8e-17
XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 471 88.4 2.8e-17
XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 471 88.4 2.8e-17
XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 471 88.5 3.2e-17
XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 471 88.5 3.2e-17
NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 471 88.5 3.2e-17
XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 471 88.5 3.5e-17
XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 471 88.5 3.5e-17
XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 471 88.5 3.5e-17
NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 471 88.5 3.5e-17
NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 471 88.5 3.5e-17
NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 471 88.5 3.5e-17
>>NP_542783 (OMIM: 616017) E3 ubiquitin-protein ligase T (341 aa)
initn: 2267 init1: 2267 opt: 2267 Z-score: 2019.2 bits: 382.0 E(85289): 9.8e-106
Smith-Waterman score: 2267; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA
250 260 270 280 290 300
310 320 330 340
pF1KE3 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
:::::::::::::::::::::::::::::::::::::::::
NP_542 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
310 320 330 340
>>NP_892030 (OMIM: 616017) E3 ubiquitin-protein ligase T (500 aa)
initn: 2254 init1: 2254 opt: 2254 Z-score: 2005.1 bits: 380.0 E(85289): 6e-105
Smith-Waterman score: 2254; 100.0% identity (100.0% similar) in 339 aa overlap (3-341:162-500)
10 20 30
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAIAA
::::::::::::::::::::::::::::::
NP_892 LICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAA
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE3 HKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 HKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAK
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE3 DMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 DMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW
260 270 280 290 300 310
160 170 180 190 200 210
pF1KE3 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE3 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE3 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK
440 450 460 470 480 490
340
pF1KE3 EPLHILHPQ
:::::::::
NP_892 EPLHILHPQ
500
>>NP_001288073 (OMIM: 616017) E3 ubiquitin-protein ligas (296 aa)
initn: 1989 init1: 1989 opt: 1989 Z-score: 1774.6 bits: 336.6 E(85289): 4.2e-92
Smith-Waterman score: 1989; 100.0% identity (100.0% similar) in 296 aa overlap (46-341:1-296)
20 30 40 50 60 70
pF1KE3 LKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNE
::::::::::::::::::::::::::::::
NP_001 MEFLKLHQFLHSKEKDILTELREEGKALNE
10 20 30
80 90 100 110 120 130
pF1KE3 EMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELIS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 RKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIM
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 PDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFW
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 LLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFME
220 230 240 250 260 270
320 330 340
pF1KE3 KLYPYFCPCLNDGGENKEPLHILHPQ
::::::::::::::::::::::::::
NP_001 KLYPYFCPCLNDGGENKEPLHILHPQ
280 290
>>NP_001288075 (OMIM: 616017) E3 ubiquitin-protein ligas (263 aa)
initn: 1573 init1: 1573 opt: 1583 Z-score: 1416.6 bits: 270.2 E(85289): 3.6e-72
Smith-Waterman score: 1606; 77.1% identity (77.1% similar) in 341 aa overlap (1-341:1-263)
10 20 30 40 50 60
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK
::::::::::::::::::::::::::::::::::
NP_001 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHK--------------------------
10 20 30
70 80 90 100 110 120
pF1KE3 DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS
::::::::
NP_001 ----------------------------------------------------DITTLLHS
40
130 140 150 160 170 180
pF1KE3 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE3 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA
170 180 190 200 210 220
310 320 330 340
pF1KE3 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
:::::::::::::::::::::::::::::::::::::::::
NP_001 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
230 240 250 260
>>NP_001288074 (OMIM: 616017) E3 ubiquitin-protein ligas (279 aa)
initn: 1567 init1: 1567 opt: 1577 Z-score: 1410.9 bits: 269.2 E(85289): 7.5e-72
Smith-Waterman score: 1840; 94.3% identity (94.3% similar) in 296 aa overlap (46-341:1-279)
20 30 40 50 60 70
pF1KE3 LKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNE
::::::::::::::::::::::::::::::
NP_001 MEFLKLHQFLHSKEKDILTELREEGKALNE
10 20 30
80 90 100 110 120 130
pF1KE3 EMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELIS
:::::::::::::::::::: :::::::::::::::::::::::
NP_001 EMELNLSQLQEQCLLAKDML-----------------DITTLLHSLEQGMKVLATRELIS
40 50 60 70
140 150 160 170 180 190
pF1KE3 RKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIM
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE3 PDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFW
140 150 160 170 180 190
260 270 280 290 300 310
pF1KE3 LLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFME
200 210 220 230 240 250
320 330 340
pF1KE3 KLYPYFCPCLNDGGENKEPLHILHPQ
::::::::::::::::::::::::::
NP_001 KLYPYFCPCLNDGGENKEPLHILHPQ
260 270
>>NP_742013 (OMIM: 605700) E3 ubiquitin-protein ligase T (488 aa)
initn: 607 init1: 454 opt: 663 Z-score: 599.5 bits: 119.9 E(85289): 1.2e-26
Smith-Waterman score: 663; 36.1% identity (63.6% similar) in 330 aa overlap (12-340:161-484)
10 20 30 40
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQ
:: :.:. .. ... . :. .
NP_742 ISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRR
140 150 160 170 180 190
50 60 70 80 90 100
pF1KE3 QHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAK
:.. :: .::. : ... .:..:.:: . . .... : ..: .. . . ...:
NP_742 QQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGK
200 210 220 230 240 250
110 120 130 140 150 160
pF1KE3 TEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCP
:..:..:::. . :.. :. . .: : . :.... : ::.. :.. :
NP_742 C-LQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNF--PRQYFALRKILKQL--
260 270 280 290 300
170 180 190 200 210 220
pF1KE3 GLSPLTLDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWY
.. .::::.:::::::::... :: . . . .:: :.:: ::...:::::. :
NP_742 -IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHY
310 320 330 340 350 360
230 240 250 260 270 280
pF1KE3 WEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNN
:::::. ::.:.::: :.:. ::: :: :.: .:: : : : : . .
NP_742 WEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVK
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE3 LDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHP
.:::.::::.: :::::. .:::::..:: :::.: : : . : .: :: : :
NP_742 PKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPP
430 440 450 460 470 480
pF1KE3 Q
NP_742 TDWE
>>NP_060677 (OMIM: 616755) E3 ubiquitin-protein ligase T (475 aa)
initn: 524 init1: 368 opt: 635 Z-score: 575.0 bits: 115.3 E(85289): 2.7e-25
Smith-Waterman score: 635; 33.0% identity (63.4% similar) in 339 aa overlap (1-337:135-470)
10 20 30
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAI
...:: : :. . .: .. :. .
NP_060 TDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQL
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE3 AAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLL
: : . :. .. : .::..:. ..: .: ::. . ..: .... ..:
NP_060 AETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRK
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE3 AKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYM
... .: . . . :: ...: . : .: :. : .: . . ..: ::.::
NP_060 VQEGAQILQERLAETDRHTFLAGVASLSERL-KG-KIHET-NLTYEDFPTSKYTGPLQYT
230 240 250 260 270 280
160 170 180 190 200
pF1KE3 VWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVL
.:. . . . : . ::::: ::: :.:: . : : .:... . . :.:.::: :.::
NP_060 IWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVL
290 300 310 320 330 340
210 220 230 240 250 260
pF1KE3 GSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALD
::..:.:: :::: ::.::.:..:...:. :::: . : .::. . ... .. .:
NP_060 GSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACT
350 360 370 380 390 400
270 280 290 300 310 320
pF1KE3 LPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDG-
: :.. ..:::::..:::. : : :::: :. .::: . : :: :: : . .
NP_060 EPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHAN
410 420 430 440 450 460
330 340
pF1KE3 GENKEPLHILHPQ
:.: .::.:
NP_060 GKNVQPLRINTVRI
470
>>XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquitin-pr (555 aa)
initn: 524 init1: 368 opt: 635 Z-score: 573.9 bits: 115.3 E(85289): 3.1e-25
Smith-Waterman score: 635; 33.0% identity (63.4% similar) in 339 aa overlap (1-337:215-550)
10 20 30
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAI
...:: : :. . .: .. :. .
XP_016 TDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQL
190 200 210 220 230 240
40 50 60 70 80 90
pF1KE3 AAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLL
: : . :. .. : .::..:. ..: .: ::. . ..: .... ..:
XP_016 AETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRK
250 260 270 280 290 300
100 110 120 130 140 150
pF1KE3 AKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYM
... .: . . . :: ...: . : .: :. : .: . . ..: ::.::
XP_016 VQEGAQILQERLAETDRHTFLAGVASLSERL-KG-KIHET-NLTYEDFPTSKYTGPLQYT
310 320 330 340 350 360
160 170 180 190 200
pF1KE3 VWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVL
.:. . . . : . ::::: ::: :.:: . : : .:... . . :.:.::: :.::
XP_016 IWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVL
370 380 390 400 410 420
210 220 230 240 250 260
pF1KE3 GSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALD
::..:.:: :::: ::.::.:..:...:. :::: . : .::. . ... .. .:
XP_016 GSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACT
430 440 450 460 470 480
270 280 290 300 310 320
pF1KE3 LPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDG-
: :.. ..:::::..:::. : : :::: :. .::: . : :: :: : . .
XP_016 EPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHAN
490 500 510 520 530 540
330 340
pF1KE3 GENKEPLHILHPQ
:.: .::.:
XP_016 GKNVQPLRINTVRI
550
>>NP_001317412 (OMIM: 616755) E3 ubiquitin-protein ligas (354 aa)
initn: 571 init1: 368 opt: 630 Z-score: 572.6 bits: 114.4 E(85289): 3.7e-25
Smith-Waterman score: 630; 33.3% identity (63.1% similar) in 336 aa overlap (4-337:17-349)
10 20 30 40
pF1KE3 MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSME
:: : :. . .: .. :. .: : . :. ..
NP_001 MPEKTAVDQPWTQALRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 FLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNS
: .::..:. ..: .: ::. . ..: .... ..: ... .: . . .
NP_001 FERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 FDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLT
:: ...: . : .: :. : .: . . ..: ::.:: .:. . . . : . ::
NP_001 HTFLAGVASLSERL-KG-KIHET-NLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALT
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 LDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVA
::: ::: :.:: . : : .:... . . :.:.::: :.::::..:.:: :::: ::
NP_001 LDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 KKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGI
.::.:..:...:. :::: . : .::. . ... .. .: : :.. ..:::::.
NP_001 EKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGV
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 YLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDG-GENKEPLHILHPQ
.:::. : : :::: :. .::: . : :: :: : . . :.: .::.:
NP_001 FLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI
300 310 320 330 340 350
>>XP_016857119 (OMIM: 616755) PREDICTED: E3 ubiquitin-pr (544 aa)
initn: 546 init1: 368 opt: 607 Z-score: 549.3 bits: 110.7 E(85289): 7.4e-24
Smith-Waterman score: 607; 34.7% identity (65.3% similar) in 300 aa overlap (40-337:243-539)
10 20 30 40 50 60
pF1KE3 GQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREE
:. .. : .::..:. ..: .: ::. .
XP_016 HRSAAAAQATTGGDQAITPDDCPPQSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEAD
220 230 240 250 260 270
70 80 90 100 110 120
pF1KE3 GKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLA
..: .... ..: ... .: . . . :: ...: . : .: :.
XP_016 TARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERL-KG-KIHE
280 290 300 310 320 330
130 140 150 160 170 180
pF1KE3 TRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHG
: .: . . ..: ::.:: .:. . . . : . ::::: ::: :.:: . : : .:
XP_016 T-NLTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYG
340 350 360 370 380
190 200 210 220 230 240
pF1KE3 DIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPL
... . . :.:.::: :.::::..:.:: :::: ::.::.:..:...:. :::: .
XP_016 NLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGSIQI
390 400 410 420 430 440
250 260 270 280 290 300
pF1KE3 TPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYT
: .::. . ... .. .: : :.. ..:::::..:::. : : :::: :. .::
XP_016 QPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYT
450 460 470 480 490 500
310 320 330 340
pF1KE3 FSNTFMEKLYPYFCPCLNDG-GENKEPLHILHPQ
: . : :: :: : . . :.: .::.:
XP_016 FREKFPGKLCSYFSPGQSHANGKNVQPLRINTVRI
510 520 530 540
341 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:35:21 2016 done: Sun Nov 6 08:35:22 2016
Total Scan time: 7.170 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]