Result of FASTA (omim) for
pFN21AE3947
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3947, 1098 aa
1>>>pF1KE3947 1098 - 1098 aa - 1098 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1161+/-0.000408; mu= 18.2240+/- 0.026
mean_var=87.7310+/-17.517, 0's: 0 Z-trim(112.4): 46 B-trim: 22 in 1/52
Lambda= 0.136930
statistics sampled from 21300 (21345) to 21300 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.25), width: 16
Scan time: 14.000
The best scores are: opt bits E(85289)
NP_055105 (OMIM: 611258,613887) tudor domain-conta (1098) 7326 1458.2 0
NP_001289813 (OMIM: 611258,613887) tudor domain-co (1024) 6842 1362.6 0
XP_006717089 (OMIM: 611258,613887) PREDICTED: tudo ( 653) 4161 832.8 0
XP_005270036 (OMIM: 605796) PREDICTED: tudor domai (1113) 232 56.8 8.3e-07
XP_011538265 (OMIM: 605796) PREDICTED: tudor domai (1180) 232 56.8 8.7e-07
XP_011538262 (OMIM: 605796) PREDICTED: tudor domai (1189) 232 56.8 8.7e-07
XP_005270035 (OMIM: 605796) PREDICTED: tudor domai (1189) 232 56.8 8.7e-07
XP_011538263 (OMIM: 605796) PREDICTED: tudor domai (1189) 232 56.8 8.7e-07
XP_011538264 (OMIM: 605796) PREDICTED: tudor domai (1189) 232 56.8 8.7e-07
XP_011538261 (OMIM: 605796) PREDICTED: tudor domai (1189) 232 56.8 8.7e-07
NP_942090 (OMIM: 605796) tudor domain-containing p (1189) 232 56.8 8.7e-07
XP_016880680 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 203 51.0 3.7e-05
XP_016880678 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 203 51.0 3.7e-05
XP_005257766 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 203 51.0 3.7e-05
XP_005257764 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 203 51.0 3.7e-05
NP_001229831 (OMIM: 602449) A-kinase anchor protei ( 903) 203 51.0 3.7e-05
XP_016880679 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 203 51.0 3.7e-05
NP_003479 (OMIM: 602449) A-kinase anchor protein 1 ( 903) 203 51.0 3.7e-05
NP_001229832 (OMIM: 602449) A-kinase anchor protei ( 903) 203 51.0 3.7e-05
XP_016871904 (OMIM: 605796) PREDICTED: tudor domai ( 999) 192 48.9 0.00018
>>NP_055105 (OMIM: 611258,613887) tudor domain-containin (1098 aa)
initn: 7326 init1: 7326 opt: 7326 Z-score: 7817.1 bits: 1458.2 E(85289): 0
Smith-Waterman score: 7326; 99.8% identity (99.8% similar) in 1098 aa overlap (1-1098:1-1098)
10 20 30 40 50 60
pF1KE3 MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 IKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 AKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVI
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_055 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEEN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAV
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_055 KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTD
1030 1040 1050 1060 1070 1080
1090
pF1KE3 TWIHDFMSEYLIELSKVN
::::::::::::::::::
NP_055 TWIHDFMSEYLIELSKVN
1090
>>NP_001289813 (OMIM: 611258,613887) tudor domain-contai (1024 aa)
initn: 6842 init1: 6842 opt: 6842 Z-score: 7300.9 bits: 1362.6 E(85289): 0
Smith-Waterman score: 6842; 99.8% identity (99.8% similar) in 1024 aa overlap (75-1098:1-1024)
50 60 70 80 90 100
pF1KE3 GFPTLEAYLRSVPAVVRIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQ
::::::::::::::::::::::::::::::
NP_001 MACTETARIAQLVARQRSSKRKTGRQVNCQ
10 20 30
110 120 130 140 150 160
pF1KE3 MRVKKTMPFFLEGKPKATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRVKKTMPFFLEGKPKATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLH
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 TTLGNEAFKDIPVQRHVTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLGNEAFKDIPVQRHVTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 KPPASYTYKMDEVQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPPASYTYKMDEVQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHIC
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 TVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 VADLLVKYTSGLWASALPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADLLVKYTSGLWASALPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYA
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 KLPLPTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPLLMIPTEAS
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 KLPLPTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEAS
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 PSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 EEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEV
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 LSDDPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDDPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLE
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 VHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLP
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 FCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAI
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKN
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE3 FPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDV
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE3 IKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEE
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE3 MILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYDKHELVNIRK
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_001 MILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRK
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KE3 VQPLVDMFRKLPFQAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPLVDMFRKLPFQAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWD
940 950 960 970 980 990
1070 1080 1090
pF1KE3 RKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
::::::::::::::::::::::::::::::::::
NP_001 RKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
1000 1010 1020
>>XP_006717089 (OMIM: 611258,613887) PREDICTED: tudor do (653 aa)
initn: 4161 init1: 4161 opt: 4161 Z-score: 4441.5 bits: 832.8 E(85289): 0
Smith-Waterman score: 4161; 99.0% identity (99.4% similar) in 625 aa overlap (474-1098:29-653)
450 460 470 480 490 500
pF1KE3 SANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYS
::. . :::::::::::::::::::::::
XP_006 MAFGYLSFHIFTKSYIKKTLIKEFYNSLNTGLIFARYVGKDYSAAQELMEDEMKEYYS
10 20 30 40 50
510 520 530 540 550 560
pF1KE3 KNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKL
60 70 80 90 100 110
570 580 590 600 610 620
pF1KE3 NPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTS
120 130 140 150 160 170
630 640 650 660 670 680
pF1KE3 GEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLL
180 190 200 210 220 230
690 700 710 720 730 740
pF1KE3 RKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVT
240 250 260 270 280 290
750 760 770 780 790 800
pF1KE3 SVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSI
300 310 320 330 340 350
810 820 830 840 850 860
pF1KE3 KVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNSK
360 370 380 390 400 410
870 880 890 900 910 920
pF1KE3 NGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACH
420 430 440 450 460 470
930 940 950 960 970 980
pF1KE3 PGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILT
480 490 500 510 520 530
990 1000 1010 1020 1030 1040
pF1KE3 NGLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKCNQWSEEASMVFRNH
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKCNQWSEEASMVFRNH
540 550 560 570 580 590
1050 1060 1070 1080 1090
pF1KE3 VEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
600 610 620 630 640 650
>>XP_005270036 (OMIM: 605796) PREDICTED: tudor domain-co (1113 aa)
initn: 315 init1: 109 opt: 232 Z-score: 243.2 bits: 56.8 E(85289): 8.3e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_005 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_005 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_005 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_005 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_005 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_005 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_005 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_005 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_005 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_005 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_005 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_005 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_011538265 (OMIM: 605796) PREDICTED: tudor domain-co (1180 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_011 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_011 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_011 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_011 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_011 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_011 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_011 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_011 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_011 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_011 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_011 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_011538262 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_011 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_011 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_011 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_011 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_011 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_011 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_011 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_011 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_011 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_011 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_011 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_005270035 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_005 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_005 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_005 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_005 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_005 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_005 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_005 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_005 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_005 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_005 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_005 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_005 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_011538263 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_011 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_011 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_011 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_011 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_011 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_011 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_011 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_011 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_011 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_011 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_011 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_011538264 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_011 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_011 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_011 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_011 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_011 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_011 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_011 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_011 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_011 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_011 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_011 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
>>XP_011538261 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa)
initn: 378 init1: 109 opt: 232 Z-score: 242.8 bits: 56.8 E(85289): 8.7e-07
Smith-Waterman score: 412; 25.2% identity (51.3% similar) in 647 aa overlap (469-1059:270-867)
440 450 460 470 480 490
pF1KE3 ESIAESANTFMEDITVPLLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEM
:.:... .. .. ... .. . .
XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL
240 250 260 270 280 290
500 510 520 530 540 550
pF1KE3 KEYYSK--NPKITPVQAVNVGQL-LAVNAEEDAWLRA--QVISTEENKIKVCYVDYGFSE
:: :.. . ::. :.. .: . ...: :: : ......: .: :.::: :
XP_011 KETYANVHEKDYIPVK----GEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEE
300 310 320 330 340 350
560 570 580 590
pF1KE3 NVEKSKAYKLNPKFCSLSFQATKCKLAGL----------EVLSDDPDL------VKVVES
. .. :.:: .. . : :: .:.. . . : : .:.:.
XP_011 IIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIVDI
360 370 380 390 400 410
600 610 620 630
pF1KE3 LTCGKI-FAVEI--------LDKADIPLVVLYDTSGED------------DININATCLK
: . ::::. ::.. : . ::.: :.. .: .
XP_011 LEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTENN
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 AICDKSLEVH----LQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHC
. ::: . :.: . .: :..: . ..:: .: ::..: .. : :
XP_011 IVVDKSDLIPKVLTLNVGDEFCGV-VAHIQTPEDFFCQQLQSG-RKLAELQASLSKY--C
480 490 500 510 520 530
700 710 720 730 740
pF1KE3 KHMTSEC-FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSE
.. . : : : :: : .: :. . : ... : ..: :. ... .
XP_011 DQLPPRSDF--YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMR
540 550 560 570 580
750 760 770 780 790 800
pF1KE3 LREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVD
: : :..:. .: ::::: :: . :.:.:::.:. .. : : . ..:: ::
XP_011 LCPIIPKLLE----LPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQN-KIITVKV--VD
590 600 610 620 630 640
810 820 830 840 850 860
pF1KE3 ETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAISSGADSPNS-KNGNMP
. .. . : :. .. :: :... . .: . .. : .. :.:.. :. ..:
XP_011 KLENSSLVELIDKSE--TPHVSVSKVLLDAGFAVGEQ----SMVT---DKPSDVKETSVP
650 660 670 680 690
870 880 890 900 910 920
pF1KE3 MSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFV
. : :. . : : . ::.: .:: : : :: :
XP_011 L-GVEGKVNPLEWTWV--ELGVDQT--------------------VDVVVCVIYSPGEFY
700 710 720 730
930 940 950 960 970 980
pF1KE3 IQPWQE--IHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRVLLKGILTN
. .: ..::. : . . . . . . .: : : ...:.:.:.: :: :
XP_011 CHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCCAFFAGDGSWYRALVKEILPN
740 750 760 770 780 790
990 1000 1010 1020 1030 1040
pF1KE3 GLVSVYELDYDKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC--NQWSEEASMVFRN
: :.:. .:: . : :. ... . . : .::::.. ::: .. ..::::: :.
XP_011 GHVKVHFVDYGNIEEVTADELRMISSTFLNLPFQGIRCQLADIQSRNKHWSEEAITRFQM
800 810 820 830 840 850
1050 1060 1070 1080 1090
pF1KE3 HVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIELSKVN
: : : : : ::
XP_011 CVAGIKLQARVVEVTENGIGVELTDLSTCYPRIISDVLIDEHLVLKSASPHKDLPNDRLV
860 870 880 890 900 910
1098 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:41:24 2016 done: Sun Nov 6 08:41:26 2016
Total Scan time: 14.000 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]