Result of FASTA (omim) for
pFN21AE3942
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3942, 433 aa
1>>>pF1KE3942 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4927+/-0.00037; mu= 18.4136+/- 0.023
mean_var=123.1467+/-26.800, 0's: 0 Z-trim(116.8): 99 B-trim: 2147 in 2/53
Lambda= 0.115575
statistics sampled from 28060 (28171) to 28060 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.33), width: 16
Scan time: 9.170
The best scores are: opt bits E(85289)
NP_114404 (OMIM: 606130) RING finger protein 26 [H ( 433) 2846 485.9 8.8e-137
XP_016878582 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 514) 188 42.8 0.0026
NP_001135763 (OMIM: 607559) E3 ubiquitin-protein l ( 530) 188 42.8 0.0026
XP_005255278 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 530) 188 42.8 0.0026
XP_016878581 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 531) 188 42.8 0.0026
XP_011520743 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 539) 188 42.8 0.0026
XP_005255277 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 552) 188 42.8 0.0027
NP_001135762 (OMIM: 607559) E3 ubiquitin-protein l ( 552) 188 42.8 0.0027
XP_016878580 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 553) 188 42.8 0.0027
XP_005255276 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 553) 188 42.8 0.0027
NP_001135761 (OMIM: 607559) E3 ubiquitin-protein l ( 554) 188 42.8 0.0027
XP_005255275 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 555) 188 42.8 0.0027
NP_056061 (OMIM: 607559) E3 ubiquitin-protein liga ( 576) 188 42.8 0.0028
XP_005255274 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 577) 188 42.8 0.0028
XP_011520744 (OMIM: 607559) PREDICTED: E3 ubiquiti ( 339) 184 41.9 0.0031
XP_016870773 (OMIM: 610933,614436) PREDICTED: E3 u ( 460) 183 41.9 0.0042
XP_016876421 (OMIM: 606138) PREDICTED: cell growth ( 272) 179 40.9 0.0048
XP_016876420 (OMIM: 606138) PREDICTED: cell growth ( 272) 179 40.9 0.0048
XP_011534664 (OMIM: 606138) PREDICTED: cell growth ( 272) 179 40.9 0.0048
NP_006559 (OMIM: 606138) cell growth regulator wit ( 332) 179 41.0 0.0055
NP_647478 (OMIM: 605737) baculoviral IAP repeat-co ( 298) 177 40.6 0.0065
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690) 178 41.2 0.0098
NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-pr ( 696) 178 41.2 0.0099
>>NP_114404 (OMIM: 606130) RING finger protein 26 [Homo (433 aa)
initn: 2846 init1: 2846 opt: 2846 Z-score: 2576.6 bits: 485.9 E(85289): 8.8e-137
Smith-Waterman score: 2846; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KE3 MEAVYLVVNGLGLVLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MEAVYLVVNGLGLVLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VLLSLLALIEAVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VLLSLLALIEAVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NVVSSGHALLRQACDICAIAMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVTGPLWRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 NVVSSGHALLRQACDICAIAMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVTGPLWRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 TVTVLHPDFTLRLATQALSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TVTVLHPDFTLRLATQALSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PNRGGAPGAPQGDPMRVFSVRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 PNRGGAPGAPQGDPMRVFSVRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 PPGGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 PPGGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPL
370 380 390 400 410 420
430
pF1KE3 CRRGILQTLNVYL
:::::::::::::
NP_114 CRRGILQTLNVYL
430
>>XP_016878582 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (514 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.6 bits: 42.8 E(85289): 0.0026
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:215-287)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_016 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
190 200 210 220 230
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_016 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
240 250 260 270 280 290
XP_016 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
300 310 320 330 340 350
>>NP_001135763 (OMIM: 607559) E3 ubiquitin-protein ligas (530 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.4 bits: 42.8 E(85289): 0.0026
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:253-325)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
NP_001 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
NP_001 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
NP_001 ALSPVSFSPVLAQSLEHDEHSNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITY
340 350 360 370 380 390
>>XP_005255278 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (530 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.4 bits: 42.8 E(85289): 0.0026
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:253-325)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_005 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_005 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
XP_005 ALSPVSFSPVLAQSLEHDEHSNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITY
340 350 360 370 380 390
>>XP_016878581 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (531 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.4 bits: 42.8 E(85289): 0.0026
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:254-326)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_016 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_016 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
XP_016 ALSPVSFSPVLAQSLEHDEHSNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITY
340 350 360 370 380 390
>>XP_011520743 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (539 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.3 bits: 42.8 E(85289): 0.0026
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:216-288)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_011 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
190 200 210 220 230 240
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_011 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
250 260 270 280 290
XP_011 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
300 310 320 330 340 350
>>XP_005255277 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (552 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.2 bits: 42.8 E(85289): 0.0027
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:253-325)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_005 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_005 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
XP_005 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
340 350 360 370 380 390
>>NP_001135762 (OMIM: 607559) E3 ubiquitin-protein ligas (552 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.2 bits: 42.8 E(85289): 0.0027
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:253-325)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
NP_001 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
NP_001 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
NP_001 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
340 350 360 370 380 390
>>XP_016878580 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (553 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.2 bits: 42.8 E(85289): 0.0027
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:254-326)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_016 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_016 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
XP_016 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
340 350 360 370 380 390
>>XP_005255276 (OMIM: 607559) PREDICTED: E3 ubiquitin-pr (553 aa)
initn: 154 init1: 154 opt: 188 Z-score: 180.2 bits: 42.8 E(85289): 0.0027
Smith-Waterman score: 188; 35.8% identity (67.9% similar) in 81 aa overlap (350-427:254-326)
320 330 340 350 360 370
pF1KE3 VRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKK
. : : :..: ..: ..... ..
XP_005 AFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDD-----ENSDNSNE
230 240 250 260 270
380 390 400 410 420 430
pF1KE3 CVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCR---RGILQTLNVYL
::.: .. . .:.::::::::: .:.. : :. . :::.:: :..::
XP_005 CVVCLSDLRDTLILPCRHLCLCTSCADTL-RYQA--NNCPICRLPFRALLQIRAVRKKPG
280 290 300 310 320 330
XP_005 ALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEA
340 350 360 370 380 390
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:44:18 2016 done: Sun Nov 6 08:44:19 2016
Total Scan time: 9.170 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]