FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3923, 447 aa
  1>>>pF1KE3923 447 - 447 aa - 447 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6438+/-0.000887; mu= 17.4334+/- 0.054
 mean_var=94.5389+/-18.327, 0's: 0 Z-trim(108.2): 13  B-trim: 44 in 1/52
 Lambda= 0.131907
 statistics sampled from 10076 (10084) to 10076 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.31), width:  16
 Scan time:  2.140

The best scores are:                                      opt bits E(32554)
CCDS5242.1 FBXO5 gene_id:26271|Hs108|chr6          ( 447) 2990 579.3 2.7e-165
CCDS47501.1 FBXO5 gene_id:26271|Hs108|chr6         ( 401) 2666 517.6 9.2e-147
CCDS47904.1 FBXO43 gene_id:286151|Hs108|chr8       ( 708)  356 78.2   3e-14


>>CCDS5242.1 FBXO5 gene_id:26271|Hs108|chr6               (447 aa)
 initn: 2990 init1: 2990 opt: 2990  Z-score: 3080.9  bits: 579.3 E(32554): 2.7e-165
Smith-Waterman score: 2990; 99.8% identity (100.0% similar) in 447 aa overlap (1-447:1-447)

               10        20        30        40        50        60
pF1KE3 MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 KLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVELETESKRLHNKEN
       ::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS52 KLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKEN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 QHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 QSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 LECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 RVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 RVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 EFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 EFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCS
              370       380       390       400       410       420

              430       440       
pF1KE3 DGKLLKASCKIGPLPGTKKSKKNLRRL
       :::::::::::::::::::::::::::
CCDS52 DGKLLKASCKIGPLPGTKKSKKNLRRL
              430       440       

>>CCDS47501.1 FBXO5 gene_id:26271|Hs108|chr6              (401 aa)
 initn: 2666 init1: 2666 opt: 2666  Z-score: 2748.3  bits: 517.6 E(32554): 9.2e-147
Smith-Waterman score: 2666; 99.8% identity (100.0% similar) in 401 aa overlap (47-447:1-401)

         20        30        40        50        60        70      
pF1KE3 CSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGLKLVKPDDIGRLVSYTP
                                     ::::::::::::::::::::::::::::::
CCDS47                               MKCDFNCNHVHSGLKLVKPDDIGRLVSYTP
                                             10        20        30

         80        90       100       110       120       130      
pF1KE3 AYLEGSCKDCIKDYERLSCIGSPIVSPRIVELETESKRLHNKENQHVQQTLNSTNEIEAL
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS47 AYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKENQHVQQTLNSTNEIEAL
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KE3 ETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLH
              100       110       120       130       140       150

        200       210       220       230       240       250      
pF1KE3 FEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLR
              160       170       180       190       200       210

        260       270       280       290       300       310      
pF1KE3 HVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 HVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTR
              220       230       240       250       260       270

        320       330       340       350       360       370      
pF1KE3 EYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLK
              280       290       300       310       320       330

        380       390       400       410       420       430      
pF1KE3 ACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPG
              340       350       360       370       380       390

        440       
pF1KE3 TKKSKKNLRRL
       :::::::::::
CCDS47 TKKSKKNLRRL
              400 

>>CCDS47904.1 FBXO43 gene_id:286151|Hs108|chr8            (708 aa)
 initn: 518 init1: 258 opt: 356  Z-score: 369.3  bits: 78.2 E(32554): 3e-14
Smith-Waterman score: 535; 31.4% identity (60.9% similar) in 379 aa overlap (80-447:352-708)

      50        60        70        80        90       100         
pF1KE3 DFNCNHVHSGLKLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVELE
                                     ::: .. .. ..    .:. : . : .   
CCDS47 PEVRGSISTPEDSGFNSLSLEKSEDSLSDQEGSFQELLQKHKGTPKVGDTIRKTRHL---
             330       340       350       360       370           

     110       120       130       140       150       160         
pF1KE3 TESKRLHNKENQHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENF
        .:.:: . ..:  :.        :. : ... . .. .  .  :..::   :.:  .. 
CCDS47 GRSRRLSTLREQSSQS--------ETEEEKQIVHPDSEKRAAAASAISE---GQLSSDES
      380       390               400       410          420       

     170       180       190       200       210       220         
pF1KE3 GDSLQSCLLQIQSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNF
       ::      ..... .. :  .:.  : : :   . :..:. .  .  ..   : ::  . 
CCDS47 GD----LTFSLKNLSKTPALQLVHEL-FMKSKRKRLQENSGH--EFLEQGDGEKIAVLQC
           430       440        450       460         470       480

     230       240       250       260       270       280         
pF1KE3 RLQNIIGRKMGLECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDK
        : ..::.:::.: .:::.::  :.:.:.:: .: .:.  .: .: ::: .:..:. .::
CCDS47 ILAGLIGKKMGIEKLDILTELKYRNLKHILAMVLESLTAESLCSVWKVSRNWREIVVQDK
              490       500       510       520       530       540

     290          300       310       320       330       340      
pF1KE3 GA---FQLYSKAIQRVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLS
       .:    ..:   ..  .:.       :.::  .. :. : ::: .:   . ...  . ::
CCDS47 NANRRRKFYITQLKTDSEGAVLNVEDAATRLQLLNRSALRSVQAQARIPGSQREQGSTLS
              550       560       570       580       590       600

        350               360       370       380       390        
pF1KE3 NQGD------QKGSTY--SRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKR
         :.      ... :.  :...:. .:::::  .:.:: : ::.:::::. : .:. :.:
CCDS47 PWGEVLTPLASSSVTHLSSKQEEYVKVAKTLFTDEALKPCPRCQSPAKYQPYKKRGLCSR
              610       620       630       640       650       660

      400       410       420       430       440       
pF1KE3 EGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPGTKKSKKNLRRL
        .::::.:. ::: :: ...:: :   :   .   :::. .::.::.::
CCDS47 TACGFDFCVLCLCAYHGSEECSRGAA-KPRNRKDALPGSAQSKRNLKRL
              670       680        690       700        




447 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 08:54:35 2016 done: Sun Nov  6 08:54:36 2016
 Total Scan time:  2.140 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]