Result of FASTA (omim) for
pFN21AE3920
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3920, 272 aa
1>>>pF1KE3920 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8238+/-0.000316; mu= 12.7080+/- 0.020
mean_var=73.3273+/-14.856, 0's: 0 Z-trim(116.4): 92 B-trim: 0 in 0/58
Lambda= 0.149776
statistics sampled from 27470 (27563) to 27470 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.323), width: 16
Scan time: 6.250
The best scores are: opt bits E(85289)
NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 1790 395.6 5.1e-110
NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 1297 289.1 5.1e-78
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 274 68.1 2.2e-11
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 274 68.1 2.3e-11
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 274 68.1 3.1e-11
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 274 68.1 3.1e-11
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 274 68.1 3.1e-11
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 274 68.1 3.1e-11
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 274 68.1 3.1e-11
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 260 65.1 2e-10
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 253 63.5 4.6e-10
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 253 63.5 4.6e-10
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 253 63.5 4.6e-10
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 253 63.5 4.6e-10
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 253 63.5 4.7e-10
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 250 62.8 6.6e-10
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 250 62.9 7.8e-10
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 250 62.9 7.8e-10
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 250 62.9 7.8e-10
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 250 62.9 7.8e-10
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 250 62.9 7.8e-10
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 253 63.7 1.3e-09
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 188 49.5 8.6e-06
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 188 49.5 8.6e-06
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 189 49.9 1.8e-05
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 189 49.9 1.8e-05
XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 165 44.5 0.00022
NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 165 44.5 0.00025
NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 161 43.7 0.00055
NP_001002914 (OMIM: 609848) BTB/POZ domain-contain ( 232) 157 42.7 0.00074
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 156 42.5 0.00082
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 156 42.5 0.00083
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 156 42.5 0.00091
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 153 41.8 0.001
XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 153 41.8 0.001
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 156 42.6 0.0011
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 156 42.6 0.0011
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 156 42.6 0.0011
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 156 42.6 0.0012
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 156 42.6 0.0012
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 156 42.6 0.0012
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 156 42.6 0.0013
NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 154 42.1 0.0015
XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 153 41.9 0.0019
NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 152 41.7 0.002
NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 151 41.5 0.0022
NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 151 41.5 0.0023
XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 152 41.7 0.0025
NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 147 40.6 0.0033
>>NP_775876 (OMIM: 607947) potassium channel regulatory (272 aa)
initn: 1790 init1: 1790 opt: 1790 Z-score: 2096.2 bits: 395.6 E(85289): 5.1e-110
Smith-Waterman score: 1790; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GSDSTTDNQTGVRYVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVSSEDKTECY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GSDSTTDNQTGVRYVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVSSEDKTECY
190 200 210 220 230 240
250 260 270
pF1KE3 SFERIKSPEVLITNETPKPETIIIPEQSQIKK
::::::::::::::::::::::::::::::::
NP_775 SFERIKSPEVLITNETPKPETIIIPEQSQIKK
250 260 270
>>NP_955751 (OMIM: 607947) potassium channel regulatory (229 aa)
initn: 1343 init1: 1297 opt: 1297 Z-score: 1521.6 bits: 289.1 E(85289): 5.1e-78
Smith-Waterman score: 1297; 99.5% identity (99.5% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GSDSTTDNQTGVRYVSIKPDNRKLANGTNVLGLLIDTLLKEGFHLVSTRTVSSEDKTECY
::::::::::::: :
NP_955 GSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGMFL
190 200 210 220
>>XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ domain- (286 aa)
initn: 263 init1: 171 opt: 274 Z-score: 325.5 bits: 68.1 E(85289): 2.2e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ domain- (304 aa)
initn: 263 init1: 171 opt: 274 Z-score: 325.1 bits: 68.1 E(85289): 2.3e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 263 init1: 171 opt: 274 Z-score: 322.7 bits: 68.1 E(85289): 3.1e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 263 init1: 171 opt: 274 Z-score: 322.7 bits: 68.1 E(85289): 3.1e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_005 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 263 init1: 171 opt: 274 Z-score: 322.7 bits: 68.1 E(85289): 3.1e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_006 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_006 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_006 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>NP_065819 (OMIM: 613423) BTB/POZ domain-containing pro (428 aa)
initn: 263 init1: 171 opt: 274 Z-score: 322.7 bits: 68.1 E(85289): 3.1e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
NP_065 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
NP_065 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
NP_065 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 263 init1: 171 opt: 274 Z-score: 322.7 bits: 68.1 E(85289): 3.1e-11
Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (2-107:22-131)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D
: :.: :::::... :: ::. ..: : : .:. :
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD
.. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF
::.: .. :
XP_005 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
130 140 150 160 170 180
>>NP_612453 (OMIM: 610521) BTB/POZ domain-containing pro (325 aa)
initn: 292 init1: 179 opt: 260 Z-score: 308.3 bits: 65.1 E(85289): 2e-10
Smith-Waterman score: 260; 46.2% identity (67.9% similar) in 106 aa overlap (5-107:34-137)
10 20 30
pF1KE3 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARM
..: :::::....:: :. . : : : ::
NP_612 ADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRM
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 LDGRD-QEF-KMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELR
. .. ::. . :..:.:::: :: .:::.:: ::.:: : . :::::: ..::
NP_612 FTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 SLVDLLN-PYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPT
:: :. : :: :
NP_612 ELVRRLGAPQ--QPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLEL
130 140 150 160 170 180
272 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:57:00 2016 done: Sun Nov 6 08:57:01 2016
Total Scan time: 6.250 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]