Result of FASTA (omim) for
pFN21AE3916
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3916, 468 aa
1>>>pF1KE3916 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8701+/-0.000389; mu= 15.5553+/- 0.024
mean_var=82.2076+/-16.953, 0's: 0 Z-trim(113.0): 239 B-trim: 817 in 1/52
Lambda= 0.141455
statistics sampled from 21968 (22210) to 21968 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.26), width: 16
Scan time: 8.360
The best scores are: opt bits E(85289)
NP_001254501 (OMIM: 609871) TBC1 domain family mem ( 468) 3094 641.4 1.6e-183
XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain ( 468) 3094 641.4 1.6e-183
XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain ( 483) 3094 641.4 1.6e-183
NP_001254500 (OMIM: 609871) TBC1 domain family mem ( 928) 3094 641.6 2.8e-183
NP_060891 (OMIM: 609871) TBC1 domain family member ( 917) 2406 501.1 5e-141
XP_005261631 (OMIM: 610440) PREDICTED: small G pro ( 739) 659 144.6 8.9e-34
NP_056520 (OMIM: 610440) small G protein signaling ( 749) 659 144.6 9e-34
XP_005261630 (OMIM: 610440) PREDICTED: small G pro ( 756) 659 144.6 9.1e-34
XP_005261629 (OMIM: 610440) PREDICTED: small G pro ( 766) 659 144.6 9.2e-34
NP_001288778 (OMIM: 610440) small G protein signal ( 660) 652 143.1 2.2e-33
XP_016884266 (OMIM: 610440) PREDICTED: small G pro ( 672) 652 143.1 2.2e-33
XP_016884265 (OMIM: 610440) PREDICTED: small G pro ( 682) 652 143.1 2.2e-33
XP_016884264 (OMIM: 610440) PREDICTED: small G pro ( 686) 652 143.1 2.3e-33
XP_011528464 (OMIM: 610440) PREDICTED: small G pro ( 686) 652 143.1 2.3e-33
XP_005261632 (OMIM: 610440) PREDICTED: small G pro ( 699) 652 143.1 2.3e-33
XP_011528461 (OMIM: 610440) PREDICTED: small G pro ( 703) 652 143.1 2.3e-33
XP_011528462 (OMIM: 610440) PREDICTED: small G pro ( 703) 652 143.1 2.3e-33
XP_016884269 (OMIM: 610440) PREDICTED: small G pro ( 583) 524 117.0 1.4e-25
XP_016884268 (OMIM: 610440) PREDICTED: small G pro ( 600) 524 117.0 1.5e-25
XP_011528463 (OMIM: 610440) PREDICTED: small G pro ( 600) 524 117.0 1.5e-25
NP_001191169 (OMIM: 610020) TBC1 domain family mem ( 515) 469 105.7 3.1e-22
NP_114143 (OMIM: 610020) TBC1 domain family member ( 508) 461 104.1 9.5e-22
NP_940919 (OMIM: 610831) carabin isoform 1 [Homo s ( 446) 450 101.8 4e-21
XP_006718603 (OMIM: 610831) PREDICTED: carabin iso ( 446) 450 101.8 4e-21
XP_006718602 (OMIM: 610831) PREDICTED: carabin iso ( 446) 450 101.8 4e-21
XP_006718601 (OMIM: 610831) PREDICTED: carabin iso ( 446) 450 101.8 4e-21
NP_056342 (OMIM: 613620) TBC1 domain family member ( 808) 436 99.1 4.8e-20
XP_011528460 (OMIM: 610440) PREDICTED: small G pro ( 718) 433 98.4 6.6e-20
XP_016884267 (OMIM: 610440) PREDICTED: small G pro ( 651) 432 98.2 7.1e-20
XP_011543304 (OMIM: 610831) PREDICTED: carabin iso ( 313) 418 95.2 2.8e-19
XP_011511972 (OMIM: 609850) PREDICTED: TBC1 domain ( 494) 374 86.3 2.1e-16
XP_006714064 (OMIM: 609850) PREDICTED: TBC1 domain ( 546) 374 86.3 2.2e-16
XP_016857774 (OMIM: 602942) PREDICTED: ecotropic v ( 741) 375 86.6 2.5e-16
XP_016857773 (OMIM: 602942) PREDICTED: ecotropic v ( 777) 375 86.6 2.6e-16
XP_016857772 (OMIM: 602942) PREDICTED: ecotropic v ( 785) 375 86.6 2.6e-16
NP_005656 (OMIM: 602942) ecotropic viral integrati ( 810) 375 86.6 2.7e-16
XP_016857770 (OMIM: 602942) PREDICTED: ecotropic v ( 818) 375 86.6 2.7e-16
NP_001295177 (OMIM: 602942) ecotropic viral integr ( 821) 375 86.6 2.7e-16
XP_016857769 (OMIM: 602942) PREDICTED: ecotropic v ( 826) 375 86.6 2.7e-16
XP_016872462 (OMIM: 605405) PREDICTED: USP6 N-term ( 851) 375 86.6 2.8e-16
XP_016857766 (OMIM: 602942) PREDICTED: ecotropic v ( 854) 375 86.7 2.8e-16
XP_016857765 (OMIM: 602942) PREDICTED: ecotropic v ( 859) 375 86.7 2.8e-16
XP_016857760 (OMIM: 602942) PREDICTED: ecotropic v ( 903) 375 86.7 2.9e-16
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778) 373 86.2 3.4e-16
NP_055672 (OMIM: 609238) rab GTPase-activating pro ( 815) 373 86.2 3.6e-16
NP_055503 (OMIM: 605405) USP6 N-terminal-like prot ( 828) 373 86.2 3.6e-16
XP_006711756 (OMIM: 609238) PREDICTED: rab GTPase- ( 985) 374 86.5 3.6e-16
NP_001073960 (OMIM: 605405) USP6 N-terminal-like p ( 845) 373 86.2 3.7e-16
XP_016872460 (OMIM: 605405) PREDICTED: USP6 N-term ( 846) 373 86.2 3.7e-16
XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase- (1014) 374 86.5 3.7e-16
>>NP_001254501 (OMIM: 609871) TBC1 domain family member (468 aa)
initn: 3094 init1: 3094 opt: 3094 Z-score: 3416.0 bits: 641.4 E(85289): 1.6e-183
Smith-Waterman score: 3094; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE3 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGFLTVPDYEVEDLKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGFLTVPDYEVEDLKLLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRWLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRWLVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQ
370 380 390 400 410 420
430 440 450 460
pF1KE3 LRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVEGEA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVEGEA
430 440 450 460
>>XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain fam (468 aa)
initn: 3094 init1: 3094 opt: 3094 Z-score: 3416.0 bits: 641.4 E(85289): 1.6e-183
Smith-Waterman score: 3094; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE3 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGFLTVPDYEVEDLKLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGFLTVPDYEVEDLKLLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRWLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRWLVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQ
370 380 390 400 410 420
430 440 450 460
pF1KE3 LRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVEGEA
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVEGEA
430 440 450 460
>>XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain fam (483 aa)
initn: 3094 init1: 3094 opt: 3094 Z-score: 3415.8 bits: 641.4 E(85289): 1.6e-183
Smith-Waterman score: 3094; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:16-483)
10 20 30 40
pF1KE3 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQ
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAVCSEPRRALKDDMEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 VESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 LTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 VPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 CPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 ADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 LLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 AFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVE
430 440 450 460 470 480
pF1KE3 GEA
:::
XP_016 GEA
>>NP_001254500 (OMIM: 609871) TBC1 domain family member (928 aa)
initn: 3094 init1: 3094 opt: 3094 Z-score: 3411.5 bits: 641.6 E(85289): 2.8e-183
Smith-Waterman score: 3094; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:461-928)
10 20 30
pF1KE3 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEK
::::::::::::::::::::::::::::::
NP_001 HPPDQSPLRPDAANRDFLSQQGKIEHLKDDMEAYRTQNCFLNSEIHQVTKIWRKVAEKEK
440 450 460 470 480 490
40 50 60 70 80 90
pF1KE3 ALLTKCAYLQARNCQVESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLTKCAYLQARNCQVESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSD
500 510 520 530 540 550
100 110 120 130 140 150
pF1KE3 SIELSPISKYDEYGFLTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIELSPISKYDEYGFLTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALG
560 570 580 590 600 610
160 170 180 190 200 210
pF1KE3 DLVPSAELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLVPSAELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQI
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 ELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEE
680 690 700 710 720 730
280 290 300 310 320 330
pF1KE3 SAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTF
740 750 760 770 780 790
340 350 360 370 380 390
pF1KE3 NWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLR
800 810 820 830 840 850
400 410 420 430 440 450
pF1KE3 FFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASR
860 870 880 890 900 910
460
pF1KE3 RRAVSEGCASEDEVEGEA
::::::::::::::::::
NP_001 RRAVSEGCASEDEVEGEA
920
>>NP_060891 (OMIM: 609871) TBC1 domain family member 2A (917 aa)
initn: 2402 init1: 2402 opt: 2406 Z-score: 2652.8 bits: 501.1 E(85289): 5e-141
Smith-Waterman score: 2995; 97.6% identity (97.6% similar) in 468 aa overlap (1-468:461-917)
10 20 30
pF1KE3 MEAYRTQNCFLNSEIHQVTKIWRKVAEKEK
::::::::::::::::::::::::::::::
NP_060 HPPDQSPLRPDAANRDFLSQQGKIEHLKDDMEAYRTQNCFLNSEIHQVTKIWRKVAEKEK
440 450 460 470 480 490
40 50 60 70 80 90
pF1KE3 ALLTKCAYLQARNCQVESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALLTKCAYLQARNCQVESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSD
500 510 520 530 540 550
100 110 120 130 140 150
pF1KE3 SIELSPISKYDEYGFLTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SIELSPISKYDEYGFLTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALG
560 570 580 590 600 610
160 170 180 190 200 210
pF1KE3 DLVPSAELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DLVPSAELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQI
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 ELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEE
680 690 700 710 720 730
280 290 300 310 320 330
pF1KE3 SAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTF
740 750 760 770 780 790
340 350 360 370 380 390
pF1KE3 NWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLR
::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_060 NWFLVVFADSLISNILLRVWDAFLYEGTK-----------YNEKEILRLQNGLEIYQYLR
800 810 820 830
400 410 420 430 440 450
pF1KE3 FFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASR
840 850 860 870 880 890
460
pF1KE3 RRAVSEGCASEDEVEGEA
::::::::::::::::::
NP_060 RRAVSEGCASEDEVEGEA
900 910
>>XP_005261631 (OMIM: 610440) PREDICTED: small G protein (739 aa)
initn: 479 init1: 403 opt: 659 Z-score: 727.4 bits: 144.6 E(85289): 8.9e-34
Smith-Waterman score: 663; 33.3% identity (61.0% similar) in 415 aa overlap (77-465:22-419)
50 60 70 80 90 100
pF1KE3 ESKYLAGLRRLQEALGDEASECSELLRQLVQEAL-QWEAGEASSDSIELSPISKYDEYGF
:: : .. : :... :. :::.::
XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFY----YDEFGF
10 20 30 40
110 120 130 140 150
pF1KE3 LTVPDYEVED-LKLLAKIQALESRSHHLLGLEAVDRPLRERWAA---------LGDL---
. . : .:::. .: : : : :: : .:::
XP_005 RVYKEEGDEPGSSLLANSPLME------------DAPQRLRWQAHLEFTHNHDVGDLTWD
50 60 70 80 90
160 170 180 190 200
pF1KE3 -----VPSAE-LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPA
.: .: :..:. ::.:. ::..: : .. .. :.:... .. : :
XP_005 KIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 ARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVL
:.::: :: ::.:.: :. : .::::: :..: : :::::: . .:: :: :
XP_005 AKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 EEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLS
:::. ::: . ::.: ..::.:. .:: . :.:::::. :. . :::: : .: ..::
XP_005 EEED-AFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELS
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 LVTFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIY
:.:..:::..::. . ..:::.:: :.:::..:.:. .:.... .:.:... .:. :.
XP_005 LITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 QYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLK-----A
. : . . . ... :...:. . . .. : : : :. .: .
XP_005 NTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLS
340 350 360 370 380 390
450 460
pF1KE3 EYLERRASRRRA-VSEGCASEDEVEGEA
. ..::..::.. .. .::..:
XP_005 QVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNC
400 410 420 430 440 450
>>NP_056520 (OMIM: 610440) small G protein signaling mod (749 aa)
initn: 479 init1: 403 opt: 659 Z-score: 727.3 bits: 144.6 E(85289): 9e-34
Smith-Waterman score: 663; 33.3% identity (61.0% similar) in 415 aa overlap (77-465:22-419)
50 60 70 80 90 100
pF1KE3 ESKYLAGLRRLQEALGDEASECSELLRQLVQEAL-QWEAGEASSDSIELSPISKYDEYGF
:: : .. : :... :. :::.::
NP_056 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFY----YDEFGF
10 20 30 40
110 120 130 140 150
pF1KE3 LTVPDYEVED-LKLLAKIQALESRSHHLLGLEAVDRPLRERWAA---------LGDL---
. . : .:::. .: : : : :: : .:::
NP_056 RVYKEEGDEPGSSLLANSPLME------------DAPQRLRWQAHLEFTHNHDVGDLTWD
50 60 70 80 90
160 170 180 190 200
pF1KE3 -----VPSAE-LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPA
.: .: :..:. ::.:. ::..: : .. .. :.:... .. : :
NP_056 KIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 ARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVL
:.::: :: ::.:.: :. : .::::: :..: : :::::: . .:: :: :
NP_056 AKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 EEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLS
:::. ::: . ::.: ..::.:. .:: . :.:::::. :. . :::: : .: ..::
NP_056 EEED-AFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELS
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 LVTFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIY
:.:..:::..::. . ..:::.:: :.:::..:.:. .:.... .:.:... .:. :.
NP_056 LITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 QYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLK-----A
. : . . . ... :...:. . . .. : : : :. .: .
NP_056 NTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLS
340 350 360 370 380 390
450 460
pF1KE3 EYLERRASRRRA-VSEGCASEDEVEGEA
. ..::..::.. .. .::..:
NP_056 QVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNC
400 410 420 430 440 450
>>XP_005261630 (OMIM: 610440) PREDICTED: small G protein (756 aa)
initn: 479 init1: 403 opt: 659 Z-score: 727.2 bits: 144.6 E(85289): 9.1e-34
Smith-Waterman score: 663; 33.3% identity (61.0% similar) in 415 aa overlap (77-465:22-419)
50 60 70 80 90 100
pF1KE3 ESKYLAGLRRLQEALGDEASECSELLRQLVQEAL-QWEAGEASSDSIELSPISKYDEYGF
:: : .. : :... :. :::.::
XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFY----YDEFGF
10 20 30 40
110 120 130 140 150
pF1KE3 LTVPDYEVED-LKLLAKIQALESRSHHLLGLEAVDRPLRERWAA---------LGDL---
. . : .:::. .: : : : :: : .:::
XP_005 RVYKEEGDEPGSSLLANSPLME------------DAPQRLRWQAHLEFTHNHDVGDLTWD
50 60 70 80 90
160 170 180 190 200
pF1KE3 -----VPSAE-LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPA
.: .: :..:. ::.:. ::..: : .. .. :.:... .. : :
XP_005 KIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 ARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVL
:.::: :: ::.:.: :. : .::::: :..: : :::::: . .:: :: :
XP_005 AKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 EEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLS
:::. ::: . ::.: ..::.:. .:: . :.:::::. :. . :::: : .: ..::
XP_005 EEED-AFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELS
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 LVTFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIY
:.:..:::..::. . ..:::.:: :.:::..:.:. .:.... .:.:... .:. :.
XP_005 LITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 QYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLK-----A
. : . . . ... :...:. . . .. : : : :. .: .
XP_005 NTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLS
340 350 360 370 380 390
450 460
pF1KE3 EYLERRASRRRA-VSEGCASEDEVEGEA
. ..::..::.. .. .::..:
XP_005 QVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNC
400 410 420 430 440 450
>>XP_005261629 (OMIM: 610440) PREDICTED: small G protein (766 aa)
initn: 479 init1: 403 opt: 659 Z-score: 727.2 bits: 144.6 E(85289): 9.2e-34
Smith-Waterman score: 663; 33.3% identity (61.0% similar) in 415 aa overlap (77-465:22-419)
50 60 70 80 90 100
pF1KE3 ESKYLAGLRRLQEALGDEASECSELLRQLVQEAL-QWEAGEASSDSIELSPISKYDEYGF
:: : .. : :... :. :::.::
XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFY----YDEFGF
10 20 30 40
110 120 130 140 150
pF1KE3 LTVPDYEVED-LKLLAKIQALESRSHHLLGLEAVDRPLRERWAA---------LGDL---
. . : .:::. .: : : : :: : .:::
XP_005 RVYKEEGDEPGSSLLANSPLME------------DAPQRLRWQAHLEFTHNHDVGDLTWD
50 60 70 80 90
160 170 180 190 200
pF1KE3 -----VPSAE-LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPA
.: .: :..:. ::.:. ::..: : .. .. :.:... .. : :
XP_005 KIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 ARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVL
:.::: :: ::.:.: :. : .::::: :..: : :::::: . .:: :: :
XP_005 AKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 EEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLS
:::. ::: . ::.: ..::.:. .:: . :.:::::. :. . :::: : .: ..::
XP_005 EEED-AFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELS
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 LVTFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIY
:.:..:::..::. . ..:::.:: :.:::..:.:. .:.... .:.:... .:. :.
XP_005 LITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 QYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLK-----A
. : . . . ... :...:. . . .. : : : :. .: .
XP_005 NTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLS
340 350 360 370 380 390
450 460
pF1KE3 EYLERRASRRRA-VSEGCASEDEVEGEA
. ..::..::.. .. .::..:
XP_005 QVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNC
400 410 420 430 440 450
>>NP_001288778 (OMIM: 610440) small G protein signaling (660 aa)
initn: 442 init1: 403 opt: 652 Z-score: 720.4 bits: 143.1 E(85289): 2.2e-33
Smith-Waterman score: 652; 34.9% identity (66.7% similar) in 327 aa overlap (146-465:31-356)
120 130 140 150 160 170
pF1KE3 LKLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAE-LKQLLRAGVPREHRPRV
: .. .: .: :..:. ::.:. ::..
NP_001 MSLVSVCTRKRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQL
10 20 30 40 50 60
180 190 200 210 220 230
pF1KE3 WRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDK
: : .. .. :.:... .. : ::.::: :: ::.:.: :. : .
NP_001 WMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPR
70 80 90 100 110 120
240 250 260 270 280 290
pF1KE3 LRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLT
::::: :..: : :::::: . .:: :: ::::. ::: . ::.: ..::.:. .::
NP_001 LRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEED-AFWMMSAIIEDLLPASYFSTTLL
130 140 150 160 170
300 310 320 330 340 350
pF1KE3 ASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFL
. :.:::::. :. . :::: : .: ..:::.:..:::..::. . ..:::.:: :.
NP_001 GVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFF
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE3 YEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFR
:::..:.:. .:.... .:.:... .:. :.. : . . . ... :...:. . .
NP_001 YEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLT
240 250 260 270 280 290
420 430 440 450 460
pF1KE3 MKQLRQLRMVHRERLEAELRELEQLK-----AEYLERRASRRRA-VSEGCASEDEVEGEA
.. : : : :. .: .. ..::..::.. .. .::..:
NP_001 DVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALK
300 310 320 330 340 350
NP_001 AKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHR
360 370 380 390 400 410
468 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:59:25 2016 done: Sun Nov 6 08:59:27 2016
Total Scan time: 8.360 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]