Result of FASTA (omim) for
pFN21AE3906
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3906, 459 aa
1>>>pF1KE3906 459 - 459 aa - 459 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8642+/-0.000587; mu= 10.8873+/- 0.036
mean_var=206.6908+/-48.646, 0's: 0 Z-trim(111.9): 555 B-trim: 1306 in 2/52
Lambda= 0.089210
statistics sampled from 19992 (20685) to 19992 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.243), width: 16
Scan time: 8.240
The best scores are: opt bits E(85289)
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459) 3090 411.4 2.5e-114
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500) 2321 312.5 1.6e-84
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575) 2321 312.6 1.8e-84
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453) 2319 312.2 1.9e-84
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 ( 468) 2319 312.2 1.9e-84
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494) 2319 312.2 2e-84
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543) 2319 312.3 2.1e-84
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569) 2319 312.3 2.1e-84
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481) 2311 311.2 3.9e-84
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556) 2311 311.3 4.3e-84
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433) 2138 288.9 1.9e-77
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 1861 253.1 8.5e-67
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 1700 232.5 1.7e-60
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332) 1499 206.5 9e-53
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 1413 195.3 1.8e-49
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 1405 194.3 3.4e-49
NP_001280005 (OMIM: 602857) beta-chimaerin isoform ( 274) 847 122.5 1.5e-27
NP_001280009 (OMIM: 602857) beta-chimaerin isoform ( 286) 835 120.9 4.4e-27
NP_001280008 (OMIM: 602857) beta-chimaerin isoform ( 197) 820 118.8 1.3e-26
NP_001280004 (OMIM: 602857) beta-chimaerin isoform ( 241) 749 109.8 8.4e-24
NP_001280006 (OMIM: 602857) beta-chimaerin isoform ( 260) 677 100.6 5.4e-21
XP_011519925 (OMIM: 604875) PREDICTED: unconventio (1737) 480 76.3 7.5e-13
XP_016877719 (OMIM: 604875) PREDICTED: unconventio (2547) 480 76.5 9.5e-13
NP_008832 (OMIM: 604875) unconventional myosin-IXa (2548) 480 76.5 9.5e-13
XP_011519924 (OMIM: 604875) PREDICTED: unconventio (2566) 480 76.5 9.5e-13
XP_016877718 (OMIM: 604875) PREDICTED: unconventio (2566) 480 76.5 9.5e-13
XP_011519923 (OMIM: 604875) PREDICTED: unconventio (2598) 480 76.5 9.6e-13
XP_011519922 (OMIM: 604875) PREDICTED: unconventio (2618) 480 76.5 9.6e-13
XP_016877717 (OMIM: 604875) PREDICTED: unconventio (2619) 480 76.5 9.6e-13
XP_011519921 (OMIM: 604875) PREDICTED: unconventio (2619) 480 76.5 9.6e-13
XP_006720602 (OMIM: 604875) PREDICTED: unconventio (2619) 480 76.5 9.6e-13
XP_011519920 (OMIM: 604875) PREDICTED: unconventio (2620) 480 76.5 9.6e-13
XP_011519919 (OMIM: 604875) PREDICTED: unconventio (2637) 480 76.5 9.7e-13
XP_011519916 (OMIM: 604875) PREDICTED: unconventio (2638) 480 76.5 9.7e-13
XP_011519918 (OMIM: 604875) PREDICTED: unconventio (2638) 480 76.5 9.7e-13
XP_011519917 (OMIM: 604875) PREDICTED: unconventio (2638) 480 76.5 9.7e-13
XP_011519915 (OMIM: 604875) PREDICTED: unconventio (2638) 480 76.5 9.7e-13
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 465 73.7 1.4e-12
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 465 73.7 1.5e-12
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 465 73.8 1.6e-12
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 465 73.8 1.6e-12
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 465 73.8 1.7e-12
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865) 465 73.9 1.9e-12
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867) 465 73.9 1.9e-12
NP_001269219 (OMIM: 610591) rho GTPase-activating ( 889) 465 74.0 1.9e-12
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889) 465 74.0 1.9e-12
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900) 465 74.0 1.9e-12
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 465 74.0 1.9e-12
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 465 74.0 1.9e-12
XP_011517909 (OMIM: 609870) PREDICTED: rho GTPase- (1491) 453 72.7 7.6e-12
>>NP_001813 (OMIM: 118423,604356) N-chimaerin isoform 1 (459 aa)
initn: 3090 init1: 3090 opt: 3090 Z-score: 2173.5 bits: 411.4 E(85289): 2.5e-114
Smith-Waterman score: 3090; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459)
10 20 30 40 50 60
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
370 380 390 400 410 420
430 440 450
pF1KE3 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
:::::::::::::::::::::::::::::::::::::::
NP_001 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
430 440 450
>>XP_016867211 (OMIM: 602857) PREDICTED: beta-chimaerin (500 aa)
initn: 2322 init1: 1505 opt: 2321 Z-score: 1638.2 bits: 312.5 E(85289): 1.6e-84
Smith-Waterman score: 2321; 73.4% identity (91.0% similar) in 455 aa overlap (5-459:47-500)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRIT
: :..::.::.:::::::::::::.:.::
XP_016 VYSEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKSYLYQLQQEAPRPKRII
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 CTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRN
: :::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :
XP_016 CPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLN
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 FRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNRE
.::..:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: ::
XP_016 YRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLRE
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 PAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFR
. .. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::
XP_016 KVSRR-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFR
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 GPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLV
::::::::::::::::::::.:.:::::::::::: :::::.::::..:::: :::::::
XP_016 GPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE3 KAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE
:::.:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.:
XP_016 KAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYP
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE3 DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETL
:::::::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::
XP_016 DINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETL
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE3 RYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKN
:::: :::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:
XP_016 RYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIEN
440 450 460 470 480 490
pF1KE3 EDILF
::.::
XP_016 EDVLF
500
>>XP_016867210 (OMIM: 602857) PREDICTED: beta-chimaerin (575 aa)
initn: 2322 init1: 1505 opt: 2321 Z-score: 1637.5 bits: 312.6 E(85289): 1.8e-84
Smith-Waterman score: 2321; 73.4% identity (91.0% similar) in 455 aa overlap (5-459:122-575)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRIT
: :..::.::.:::::::::::::.:.::
XP_016 IYSEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKSYLYQLQQEAPRPKRII
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE3 CTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRN
: :::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :
XP_016 CPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLN
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE3 FRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNRE
.::..:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: ::
XP_016 YRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLRE
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE3 PAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFR
. .. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::
XP_016 KVSRR-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFR
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE3 GPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLV
::::::::::::::::::::.:.:::::::::::: :::::.::::..:::: :::::::
XP_016 GPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLV
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE3 KAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE
:::.:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.:
XP_016 KAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYP
400 410 420 430 440 450
340 350 360 370 380 390
pF1KE3 DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETL
:::::::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::
XP_016 DINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETL
460 470 480 490 500 510
400 410 420 430 440 450
pF1KE3 RYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKN
:::: :::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:
XP_016 RYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIEN
520 530 540 550 560 570
pF1KE3 EDILF
::.::
XP_016 EDVLF
>>NP_001280001 (OMIM: 602857) beta-chimaerin isoform 6 [ (453 aa)
initn: 2320 init1: 1505 opt: 2319 Z-score: 1637.3 bits: 312.2 E(85289): 1.9e-84
Smith-Waterman score: 2319; 73.5% identity (91.2% similar) in 453 aa overlap (7-459:2-453)
10 20 30 40 50 60
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
:..::.::.:::::::::::::.:.:: : :::::::::::::::.:::: ::
NP_001 MDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQAD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
.:: .::.:..:::::::: ::::::::.:: :.::..:::::::::::::::::::::
NP_001 ELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
::::::::::::::.::: ::::::.::.:: :: . .. . :. . . : .. ..
NP_001 LITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRR-LSRSKNEPRKTNVTHEEHTA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG
....::::::.: .:.. .::: :::::::::::::::::::::::::::::.:.:::
NP_001 VEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
::::::::: :::::.::::..:::: ::::::::::.:.::::::.::::::.:::.::
NP_001 LNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
::::::::.. ::::::::::::::::::.:.: :::::::::::::::::::.::::.:
NP_001 GLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTY
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
:::..::: . ::.::..::.: :::::: ::::::: :::.::..::.:.::::::::
NP_001 SKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGI
360 370 380 390 400 410
430 440 450
pF1KE3 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
:::::::: :: .....:.:.:::.:.:..::.:::.::
NP_001 VFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
420 430 440 450
>>NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 [Hom (468 aa)
initn: 2320 init1: 1505 opt: 2319 Z-score: 1637.1 bits: 312.2 E(85289): 1.9e-84
Smith-Waterman score: 2319; 73.5% identity (91.2% similar) in 453 aa overlap (7-459:17-468)
10 20 30 40 50
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREF
:..::.::.:::::::::::::.:.:: : :::::::::::::
NP_004 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRF
::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.::..:::::::::::
NP_004 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 ESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDE
::::::::::::::::::::::::.::: ::::::.::.:: :: . .. . :. .
NP_004 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRR-LSRSKNEPRK
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 RDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLI
. : .. .. ....::::::.: .:.. .::: :::::::::::::::::::::::::
NP_004 TNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIR
::::.:.:::::::::::: :::::.::::..:::: ::::::::::.:.::::::.:::
NP_004 AQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 EIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDL
:::.:::.::::::::::.. ::::::::::::::::::.:.: ::::::::::::::::
NP_004 EIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 PIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKE
:::.::::.: :::..::: . ::.::..::.: :::::: ::::::: :::.::..::.
NP_004 PIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKD
360 370 380 390 400 410
420 430 440 450
pF1KE3 NLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::.::
NP_004 NFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
420 430 440 450 460
>>XP_011513409 (OMIM: 602857) PREDICTED: beta-chimaerin (494 aa)
initn: 2320 init1: 1505 opt: 2319 Z-score: 1636.9 bits: 312.2 E(85289): 2e-84
Smith-Waterman score: 2319; 73.5% identity (91.2% similar) in 453 aa overlap (7-459:43-494)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCT
:..::.::.:::::::::::::.:.:: :
XP_011 SVSSVYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 CEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFR
:::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.:
XP_011 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 LYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPA
:..:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: :: .
XP_011 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 YKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGP
.. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::::
XP_011 SRR-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGP
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 HWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKA
::::::::::::::::::.:.:::::::::::: :::::.::::..:::: :::::::::
XP_011 HWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKA
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE3 HTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDI
:.:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.: ::
XP_011 HNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE3 NIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRY
:::::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::::
XP_011 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE3 LMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNED
:: :::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::
XP_011 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED
440 450 460 470 480 490
pF1KE3 ILF
.::
XP_011 VLF
>>NP_001279998 (OMIM: 602857) beta-chimaerin isoform 3 [ (543 aa)
initn: 2320 init1: 1505 opt: 2319 Z-score: 1636.4 bits: 312.3 E(85289): 2.1e-84
Smith-Waterman score: 2319; 73.5% identity (91.2% similar) in 453 aa overlap (7-459:92-543)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCT
:..::.::.:::::::::::::.:.:: :
NP_001 FTFGKRVVFDSHCLKRQHTFADGLHSSCTSDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE3 CEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFR
:::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.:
NP_001 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE3 LYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPA
:..:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: :: .
NP_001 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE3 YKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGP
.. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::::
NP_001 SRR-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGP
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE3 HWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKA
::::::::::::::::::.:.:::::::::::: :::::.::::..:::: :::::::::
NP_001 HWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKA
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE3 HTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDI
:.:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.: ::
NP_001 HNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDI
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE3 NIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRY
:::::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::::
NP_001 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE3 LMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNED
:: :::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::
NP_001 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED
490 500 510 520 530 540
pF1KE3 ILF
.::
NP_001 VLF
>>XP_011513407 (OMIM: 602857) PREDICTED: beta-chimaerin (569 aa)
initn: 2320 init1: 1505 opt: 2319 Z-score: 1636.2 bits: 312.3 E(85289): 2.1e-84
Smith-Waterman score: 2319; 73.5% identity (91.2% similar) in 453 aa overlap (7-459:118-569)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCT
:..::.::.:::::::::::::.:.:: :
XP_011 SCTSIYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE3 CEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFR
:::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.:
XP_011 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE3 LYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPA
:..:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: :: .
XP_011 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE3 YKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGP
.. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::::
XP_011 SRR-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGP
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE3 HWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKA
::::::::::::::::::.:.:::::::::::: :::::.::::..:::: :::::::::
XP_011 HWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKA
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE3 HTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDI
:.:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.: ::
XP_011 HNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDI
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE3 NIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRY
:::::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::::
XP_011 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE3 LMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNED
:: :::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::
XP_011 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED
510 520 530 540 550 560
pF1KE3 ILF
.::
XP_011 VLF
>>NP_001279999 (OMIM: 602857) beta-chimaerin isoform 4 [ (481 aa)
initn: 2312 init1: 1505 opt: 2311 Z-score: 1631.4 bits: 311.2 E(85289): 3.9e-84
Smith-Waterman score: 2311; 73.6% identity (91.1% similar) in 451 aa overlap (9-459:32-481)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCE
.::.::.:::::::::::::.:.:: : :
NP_001 AASSNSSLSGSSVSSVYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPRE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 VENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLY
::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.::.
NP_001 VENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 YDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYK
.:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: :: . .
NP_001 HDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 KHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHW
. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::::::
NP_001 R-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 CEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHT
::::::::::::::::.:.:::::::::::: :::::.::::..:::: ::::::::::.
NP_001 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 TKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINI
:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.: ::::
NP_001 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 ITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLM
:::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::::::
NP_001 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDIL
:::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::.:
NP_001 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
430 440 450 460 470 480
pF1KE3 F
:
NP_001 F
>>XP_011513408 (OMIM: 602857) PREDICTED: beta-chimaerin (556 aa)
initn: 2312 init1: 1505 opt: 2311 Z-score: 1630.8 bits: 311.3 E(85289): 4.3e-84
Smith-Waterman score: 2311; 73.6% identity (91.1% similar) in 451 aa overlap (9-459:107-556)
10 20 30
pF1KE3 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCE
.::.::.:::::::::::::.:.:: : :
XP_011 RQHTFADGLHSSCTSIYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPRE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE3 VENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLY
::::::::::::::.:::: ::.:: .::.:..:::::::: ::::::::.:: :.::.
XP_011 VENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLF
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE3 YDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYK
.:::::::::::::::::::::::::::::::::::.::: ::::::.::.:: :: . .
XP_011 HDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSR
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE3 KHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHW
. . :. . . : .. .. ....::::::.: .:.. .::: :::::::::::::
XP_011 R-LSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE3 CEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHT
::::::::::::::::.:.:::::::::::: :::::.::::..:::: ::::::::::.
XP_011 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE3 TKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINI
:.::::::.::::::.:::.::::::::::.. ::::::::::::::::::.:.: ::::
XP_011 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE3 ITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLM
:::::::::::::::.::::.: :::..::: . ::.::..::.: :::::: :::::::
XP_011 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE3 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDIL
:::.::..::.:.:::::::::::::::: :: .....:.:.:::.:.:..::.:::.:
XP_011 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
500 510 520 530 540 550
pF1KE3 F
:
XP_011 F
459 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:04:51 2016 done: Sun Nov 6 09:04:53 2016
Total Scan time: 8.240 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]