Result of FASTA (omim) for
pFN21AE3767
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3767, 755 aa
1>>>pF1KE3767 755 - 755 aa - 755 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3896+/-0.00053; mu= 14.5188+/- 0.033
mean_var=89.4413+/-18.133, 0's: 0 Z-trim(108.5): 39 B-trim: 1188 in 2/51
Lambda= 0.135614
statistics sampled from 16556 (16580) to 16556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.539), E-opt: 0.2 (0.194), width: 16
Scan time: 12.260
The best scores are: opt bits E(85289)
NP_057321 (OMIM: 606948) anaphase-promoting comple ( 755) 4867 963.4 0
NP_001317418 (OMIM: 606948) anaphase-promoting com ( 742) 2421 484.9 5.3e-136
NP_001131031 (OMIM: 606948) anaphase-promoting com ( 643) 2369 474.7 5.4e-133
XP_016874913 (OMIM: 606948) PREDICTED: anaphase-pr ( 357) 2302 461.4 2.9e-129
XP_016874912 (OMIM: 606948) PREDICTED: anaphase-pr ( 357) 2302 461.4 2.9e-129
>>NP_057321 (OMIM: 606948) anaphase-promoting complex su (755 aa)
initn: 4867 init1: 4867 opt: 4867 Z-score: 5148.9 bits: 963.4 E(85289): 0
Smith-Waterman score: 4867; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KE3 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
670 680 690 700 710 720
730 740 750
pF1KE3 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
:::::::::::::::::::::::::::::::::::
NP_057 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
730 740 750
>>NP_001317418 (OMIM: 606948) anaphase-promoting complex (742 aa)
initn: 4776 init1: 2421 opt: 2421 Z-score: 2562.7 bits: 484.9 E(85289): 5.3e-136
Smith-Waterman score: 4754; 98.3% identity (98.3% similar) in 755 aa overlap (1-755:1-742)
10 20 30 40 50 60
pF1KE3 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
:::::::::::::: :::::::::::::::::::::::::::::::::
NP_001 LEHSVKKAVHFGLP-------------RAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
370 380 390 400
430 440 450 460 470 480
pF1KE3 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE3 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE3 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE3 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE3 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
650 660 670 680 690 700
730 740 750
pF1KE3 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
:::::::::::::::::::::::::::::::::::
NP_001 YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
710 720 730 740
>>NP_001131031 (OMIM: 606948) anaphase-promoting complex (643 aa)
initn: 4141 init1: 2369 opt: 2369 Z-score: 2508.7 bits: 474.7 E(85289): 5.4e-133
Smith-Waterman score: 4119; 98.0% identity (98.0% similar) in 656 aa overlap (100-755:1-643)
70 80 90 100 110 120
pF1KE3 GPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKT
::::::::::::::::::::::::::::::
NP_001 MAEGELKDMEQFFDDLSDSFSGTEPEVHKT
10 20 30
130 140 150 160 170 180
pF1KE3 SVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 EELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPD
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 FAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 LHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 HFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIW
::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 HFGLP-------------RAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIW
280 290 300 310
430 440 450 460 470 480
pF1KE3 RLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEV
320 330 340 350 360 370
490 500 510 520 530 540
pF1KE3 LKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAV
380 390 400 410 420 430
550 560 570 580 590 600
pF1KE3 VLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALA
440 450 460 470 480 490
610 620 630 640 650 660
pF1KE3 LSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAK
500 510 520 530 540 550
670 680 690 700 710 720
pF1KE3 CQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQE
560 570 580 590 600 610
730 740 750
pF1KE3 RNRCAMLFRQLHQELPSHGVPLINHL
::::::::::::::::::::::::::
NP_001 RNRCAMLFRQLHQELPSHGVPLINHL
620 630 640
>>XP_016874913 (OMIM: 606948) PREDICTED: anaphase-promot (357 aa)
initn: 2302 init1: 2302 opt: 2302 Z-score: 2441.8 bits: 461.4 E(85289): 2.9e-129
Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 357 aa overlap (399-755:1-357)
370 380 390 400 410 420
pF1KE3 VHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAI
::::::::::::::::::::::::::::::
XP_016 MDALKDSDLLHWKHSLSELIDISIAQKTAI
10 20 30
430 440 450 460 470 480
pF1KE3 WRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASE
40 50 60 70 80 90
490 500 510 520 530 540
pF1KE3 VLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKA
100 110 120 130 140 150
550 560 570 580 590 600
pF1KE3 VVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQAL
160 170 180 190 200 210
610 620 630 640 650 660
pF1KE3 ALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVA
220 230 240 250 260 270
670 680 690 700 710 720
pF1KE3 KCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQ
280 290 300 310 320 330
730 740 750
pF1KE3 ERNRCAMLFRQLHQELPSHGVPLINHL
:::::::::::::::::::::::::::
XP_016 ERNRCAMLFRQLHQELPSHGVPLINHL
340 350
>>XP_016874912 (OMIM: 606948) PREDICTED: anaphase-promot (357 aa)
initn: 2302 init1: 2302 opt: 2302 Z-score: 2441.8 bits: 461.4 E(85289): 2.9e-129
Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 357 aa overlap (399-755:1-357)
370 380 390 400 410 420
pF1KE3 VHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAI
::::::::::::::::::::::::::::::
XP_016 MDALKDSDLLHWKHSLSELIDISIAQKTAI
10 20 30
430 440 450 460 470 480
pF1KE3 WRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASE
40 50 60 70 80 90
490 500 510 520 530 540
pF1KE3 VLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKA
100 110 120 130 140 150
550 560 570 580 590 600
pF1KE3 VVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQAL
160 170 180 190 200 210
610 620 630 640 650 660
pF1KE3 ALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVA
220 230 240 250 260 270
670 680 690 700 710 720
pF1KE3 KCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQ
280 290 300 310 320 330
730 740 750
pF1KE3 ERNRCAMLFRQLHQELPSHGVPLINHL
:::::::::::::::::::::::::::
XP_016 ERNRCAMLFRQLHQELPSHGVPLINHL
340 350
755 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:07:15 2016 done: Sun Nov 6 07:07:17 2016
Total Scan time: 12.260 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]