Result of FASTA (omim) for
pFN21AE3761
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3761, 552 aa
1>>>pF1KE3761 552 - 552 aa - 552 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3485+/-0.000608; mu= -0.6483+/- 0.037
mean_var=512.4516+/-116.743, 0's: 0 Z-trim(116.1): 2000 B-trim: 650 in 1/51
Lambda= 0.056656
statistics sampled from 24391 (27011) to 24391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.317), width: 16
Scan time: 7.650
The best scores are: opt bits E(85289)
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 3703 318.6 3.2e-86
XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 3115 270.4 8.5e-72
XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 3115 270.4 8.5e-72
XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 3115 270.4 8.5e-72
NP_006242 (OMIM: 602739) 5'-AMP-activated protein ( 559) 2829 247.2 1e-64
XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 533) 2630 230.9 7.9e-60
NP_996790 (OMIM: 602739) 5'-AMP-activated protein ( 574) 2172 193.5 1.5e-48
XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 548) 2150 191.7 5.2e-48
XP_006714545 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 301) 1309 122.5 1.9e-27
NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 977 96.1 5e-19
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 970 95.5 6.8e-19
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 921 91.4 1e-17
NP_003948 (OMIM: 609236) serine/threonine-protein ( 668) 909 90.4 2e-17
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674) 909 90.4 2e-17
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720) 909 90.4 2.1e-17
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736) 909 90.4 2.1e-17
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758) 909 90.5 2.1e-17
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 909 90.5 2.1e-17
XP_016874025 (OMIM: 609236) PREDICTED: serine/thre ( 858) 909 90.5 2.3e-17
XP_016874022 (OMIM: 609236) PREDICTED: serine/thre ( 880) 909 90.6 2.3e-17
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 902 89.8 2.9e-17
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 902 89.9 3.1e-17
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 902 89.9 3.1e-17
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 902 89.9 3.1e-17
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 902 89.9 3.1e-17
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 902 89.9 3.1e-17
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 900 89.6 3.3e-17
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 904 90.4 3.6e-17
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261) 904 90.4 3.7e-17
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321) 904 90.4 3.8e-17
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261) 900 90.1 4.6e-17
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309) 900 90.1 4.7e-17
NP_079440 (OMIM: 614776) serine/threonine-protein (1321) 900 90.1 4.7e-17
XP_011541023 (OMIM: 614776) PREDICTED: serine/thre (1369) 900 90.1 4.8e-17
XP_005271538 (OMIM: 614776) PREDICTED: serine/thre (1369) 900 90.1 4.8e-17
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 886 88.5 7.5e-17
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 886 88.5 7.6e-17
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 886 88.5 7.6e-17
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 886 88.6 7.6e-17
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 886 88.6 7.7e-17
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 886 88.6 7.7e-17
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 886 88.6 7.7e-17
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 886 88.6 7.8e-17
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 886 88.6 8e-17
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 885 88.5 8.3e-17
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 885 88.5 8.3e-17
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 885 88.5 8.4e-17
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 885 88.5 8.4e-17
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 885 88.5 8.4e-17
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 882 88.2 9.5e-17
>>NP_006243 (OMIM: 600497) 5'-AMP-activated protein kina (552 aa)
initn: 3703 init1: 3703 opt: 3703 Z-score: 1669.0 bits: 318.6 E(85289): 3.2e-86
Smith-Waterman score: 3703; 100.0% identity (100.0% similar) in 552 aa overlap (1-552:1-552)
10 20 30 40 50 60
pF1KE3 MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
490 500 510 520 530 540
550
pF1KE3 EMCASLITTLAR
::::::::::::
NP_006 EMCASLITTLAR
550
>>XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 3115 init1: 3115 opt: 3115 Z-score: 1410.0 bits: 270.4 E(85289): 8.5e-72
Smith-Waterman score: 3115; 100.0% identity (100.0% similar) in 462 aa overlap (91-552:1-462)
70 80 90 100 110 120
pF1KE3 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
::::::::::::::::::::::::::::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
130 140 150 160 170 180
pF1KE3 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
400 410 420 430 440 450
550
pF1KE3 EMCASLITTLAR
::::::::::::
XP_016 EMCASLITTLAR
460
>>XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 3115 init1: 3115 opt: 3115 Z-score: 1410.0 bits: 270.4 E(85289): 8.5e-72
Smith-Waterman score: 3115; 100.0% identity (100.0% similar) in 462 aa overlap (91-552:1-462)
70 80 90 100 110 120
pF1KE3 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
::::::::::::::::::::::::::::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
130 140 150 160 170 180
pF1KE3 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
400 410 420 430 440 450
550
pF1KE3 EMCASLITTLAR
::::::::::::
XP_016 EMCASLITTLAR
460
>>XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 3115 init1: 3115 opt: 3115 Z-score: 1410.0 bits: 270.4 E(85289): 8.5e-72
Smith-Waterman score: 3115; 100.0% identity (100.0% similar) in 462 aa overlap (91-552:1-462)
70 80 90 100 110 120
pF1KE3 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
::::::::::::::::::::::::::::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
130 140 150 160 170 180
pF1KE3 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFF
400 410 420 430 440 450
550
pF1KE3 EMCASLITTLAR
::::::::::::
XP_016 EMCASLITTLAR
460
>>NP_006242 (OMIM: 602739) 5'-AMP-activated protein kina (559 aa)
initn: 2851 init1: 2081 opt: 2829 Z-score: 1282.8 bits: 247.2 E(85289): 1e-64
Smith-Waterman score: 2829; 76.3% identity (90.1% similar) in 553 aa overlap (2-552:13-559)
10 20 30 40
pF1KE3 MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNR
:::::::::::::::.::::::::::::::.:.:.:::::::::::::
NP_006 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 QKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHG
::::::::::::.::::::::::::::::::::::::.:.::::::::::::::::::.:
NP_006 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
:..: :.:::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_006 RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG
:::::::::::::::::::::::::::::: ::::::::::::::::.::::::::: :
NP_006 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVID
.:: :.::: :: .:: :::::::.:::::::::::::::::::.:::::::::....::
NP_006 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 DEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSG
:::.:::::::::.: ::.. ::. . :: ::::::::::::::::.:..::::.:::.
NP_006 DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-
310 320 330 340 350
350 360 370 380 390 400
pF1KE3 SFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQ
::.:: :. .:::::.: :.:..:.:: :: :: : : .:.:::::::::::
NP_006 SFLDDH--HL---TRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQ
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE3 SKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDF
:.: :::::: ::.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::
NP_006 SRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDF
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE3 KSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSV-
.:::::..: .::..::::: :... . . : ... :...: :::.:.:. : :
NP_006 RSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVD
480 490 500 510 520 530
530 540 550
pF1KE3 -SPRLGSHTMDFFEMCASLITTLAR
.:: ::::..::::::.:: ::.
NP_006 LTPRPGSHTIEFFEMCANLIKILAQ
540 550
>>XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-activate (533 aa)
initn: 2652 init1: 1882 opt: 2630 Z-score: 1195.1 bits: 230.9 E(85289): 7.9e-60
Smith-Waterman score: 2630; 75.1% identity (89.5% similar) in 523 aa overlap (32-552:17-533)
10 20 30 40 50 60
pF1KE3 AEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKI
.:.:.:::::::::::::::::::::::::
XP_016 MQVKNIRKLPCQIIQSVGKHELTGHKVAVKILNRQKIRSLDVVGKI
10 20 30 40
70 80 90 100 110 120
pF1KE3 KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQ
.::::::::::::::::::::::::.:.::::::::::::::::::.::..: :.:::::
XP_016 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 QILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 PEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSV
:::::::::::::::::: ::::::::::::::::.::::::::: :.:: :.::: ::
XP_016 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 ATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE
.:: :::::::.:::::::::::::::::::.:::::::::....:::::.::::::::
XP_016 ISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 CTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPP
:.: ::.. ::. . :: ::::::::::::::::.:..::::.:::. ::.:: :.
XP_016 CSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-SFLDD--HHLT-
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 GLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYR
.:::::.: :.:..:.:: :: :: : : .:.::::::::::::.: :::::: :
XP_016 --RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 AMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRS
:.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::.:::::..: .:
XP_016 AIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKS
410 420 430 440 450 460
490 500 510 520 530
pF1KE3 GSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSV--SPRLGSHTMDF
:..::::: :... . . : ... :...: :::.:.:. : : .:: ::::..:
XP_016 GTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEF
470 480 490 500 510 520
540 550
pF1KE3 FEMCASLITTLAR
:::::.:: ::.
XP_016 FEMCANLIKILAQ
530
>>NP_996790 (OMIM: 602739) 5'-AMP-activated protein kina (574 aa)
initn: 2837 init1: 1392 opt: 2172 Z-score: 992.5 bits: 193.5 E(85289): 1.5e-48
Smith-Waterman score: 2789; 74.3% identity (87.7% similar) in 568 aa overlap (2-552:13-574)
10 20 30 40
pF1KE3 MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNR
:::::::::::::::.::::::::::::::.:.:.:::::::::::::
NP_996 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 QKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHG
::::::::::::.::::::::::::::::::::::::.:.::::::::::::::::::.:
NP_996 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
70 80 90 100 110 120
110 120 130 140 150
pF1KE3 R---------------VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAK
: ..: :.:::::::::.::::::::::::::::::::::::::::
NP_996 RKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 IADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPF
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_996 IADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 DDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPS
::.::::::::: :.:: :.::: :: .:: :::::::.:::::::::::::::::::.
NP_996 DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 YLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIM
:::::::::....:::::.:::::::::.: ::.. ::. . :: :::::::::::::::
NP_996 YLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIM
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 NQASEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKS
:.:..::::.:::. ::.:: :. .:::::.: :.:..:.:: :: :: : :
NP_996 NEAKDFYLATSPPD-SFLDDH--HL---TRPHPERVPFLVAETPRARHTLDELNPQKSKH
370 380 390 400 410
400 410 420 430 440 450
pF1KE3 LAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMS
.:.::::::::::::.: :::::: ::.::::.:::::: :.::::::::::..: :::
NP_996 QGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMS
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE3 LQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSG
:::: ::.:.:::::.:::::..: .::..::::: :... . . : ... :...:
NP_996 LQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEV
480 490 500 510 520 530
520 530 540 550
pF1KE3 SLTGSLTGSTLSSV--SPRLGSHTMDFFEMCASLITTLAR
:::.:.:. : : .:: ::::..::::::.:: ::.
NP_996 SLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
540 550 560 570
>>XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-activate (548 aa)
initn: 2638 init1: 1392 opt: 2150 Z-score: 983.0 bits: 191.7 E(85289): 5.2e-48
Smith-Waterman score: 2590; 73.0% identity (87.0% similar) in 538 aa overlap (32-552:17-548)
10 20 30 40 50 60
pF1KE3 AEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKI
.:.:.:::::::::::::::::::::::::
XP_016 MQVKNIRKLPCQIIQSVGKHELTGHKVAVKILNRQKIRSLDVVGKI
10 20 30 40
70 80 90 100 110
pF1KE3 KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGR-----------
.::::::::::::::::::::::::.:.::::::::::::::::::.::
XP_016 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTG
50 60 70 80 90 100
120 130 140 150 160
pF1KE3 ----VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD
..: :.:::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 STKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE3 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI
::::::::::::::::::::::::::::::::: ::::::::::::::::.:::::::::
XP_016 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE3 RGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDAN
:.:: :.::: :: .:: :::::::.:::::::::::::::::::.:::::::::...
XP_016 CDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSST
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE3 VIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSP
.:::::.:::::::::.: ::.. ::. . :: ::::::::::::::::.:..::::.::
XP_016 MIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE3 PSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGI
:. ::.:: :. .:::::.: :.:..:.:: :: :: : : .:.::::::::
XP_016 PD-SFLDD--HHLT---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE3 RSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYL
::::.: :::::: ::.::::.:::::: :.::::::::::..: ::::::: ::.:.::
XP_016 RSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYL
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE3 LDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLS
:::.:::::..: .::..::::: :... . . : ... :...: :::.:.:. :
XP_016 LDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSS
470 480 490 500 510 520
530 540 550
pF1KE3 SV--SPRLGSHTMDFFEMCASLITTLAR
: .:: ::::..::::::.:: ::.
XP_016 PVDLTPRPGSHTIEFFEMCANLIKILAQ
530 540
>>XP_006714545 (OMIM: 602739) PREDICTED: 5'-AMP-activate (301 aa)
initn: 1331 init1: 646 opt: 1309 Z-score: 613.9 bits: 122.5 E(85289): 1.9e-27
Smith-Waterman score: 1309; 65.1% identity (84.7% similar) in 307 aa overlap (248-552:1-301)
220 230 240 250 260 270
pF1KE3 HVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLF
::::::.:::::::::::::::::::.:::
XP_006 MLQVDPMKRATIKDIREHEWFKQDLPKYLF
10 20 30
280 290 300 310 320 330
pF1KE3 PEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQA
::::::....:::::.:::::::::.: ::.. ::. . :: ::::::::::::::::.:
XP_006 PEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEA
40 50 60 70 80 90
340 350 360 370 380 390
pF1KE3 SEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAV
..::::.:::. ::.:: :. .:::::.: :.:..:.:: :: :: : : .:
XP_006 KDFYLATSPPD-SFLDDH--HLT---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGV
100 110 120 130 140
400 410 420 430 440 450
pF1KE3 KKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQL
.::::::::::::.: :::::: ::.::::.:::::: :.::::::::::..: ::::::
XP_006 RKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQL
150 160 170 180 190 200
460 470 480 490 500 510
pF1KE3 YLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLT
: ::.:.:::::.:::::..: .::..::::: :... . . : ... :...: :::
XP_006 YQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLT
210 220 230 240 250 260
520 530 540 550
pF1KE3 GSLTGSTLSSV--SPRLGSHTMDFFEMCASLITTLAR
.:.:. : : .:: ::::..::::::.:: ::.
XP_006 SSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
270 280 290 300
>>NP_056006 (OMIM: 608973) serine/threonine-protein kina (926 aa)
initn: 945 init1: 826 opt: 977 Z-score: 462.6 bits: 96.1 E(85289): 5e-19
Smith-Waterman score: 977; 43.4% identity (74.6% similar) in 346 aa overlap (1-340:3-344)
10 20 30 40 50
pF1KE3 MAEKQKH--DGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLD
::. .: : :..: : . ::: :.:. ::.:.:..: .::.::...... ...
NP_056 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 VVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEA
. :: ::.: .:.. ::::::::::. : . ...: ::...::.:::. .:::..: ::
NP_056 LE-KIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEA
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 RRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGS
:: : :::::::::: . .:::::: ::.::: .:: ::::::..:....::.: : :::
NP_056 RRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 PNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEY
: ::::::. :. : ::..:::: ::.::.:.::.:::: .: : ... : : :: .
NP_056 PPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 LNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLP---SYLFPEDPSYDANVID-DEA
.... :. .:: .:: :: :: .:.::.:. ..: :.:.. . .. . .:
NP_056 MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 VKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFM
: .. ... ......:: .. ...:. : :... :. .. : :
NP_056 VLRLMHSLGIDQQKTIESL-QNKSYNHFAAIYFLLVE--RLKSHRSSFPVEQRLDGRQRR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 DDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKP
NP_056 PSTIAEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEE
360 370 380 390 400 410
552 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:08:38 2016 done: Sun Nov 6 07:08:39 2016
Total Scan time: 7.650 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]