Result of FASTA (omim) for
pFN21AE3713
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3713, 2025 aa
1>>>pF1KE3713 2025 - 2025 aa - 2025 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8483+/-0.000502; mu= 6.3938+/- 0.031
mean_var=318.5070+/-64.621, 0's: 0 Z-trim(118.0): 47 B-trim: 1373 in 1/58
Lambda= 0.071865
statistics sampled from 30390 (30437) to 30390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.357), width: 16
Scan time: 18.080
The best scores are: opt bits E(85289)
NP_001001894 (OMIM: 602259) E3 ubiquitin-protein l (2025) 13556 1421.3 0
NP_003307 (OMIM: 602259) E3 ubiquitin-protein liga (2025) 13556 1421.3 0
NP_001317612 (OMIM: 602259) E3 ubiquitin-protein l (2025) 13556 1421.3 0
XP_016883949 (OMIM: 602259) PREDICTED: E3 ubiquiti (2047) 13556 1421.3 0
XP_016883950 (OMIM: 602259) PREDICTED: E3 ubiquiti (2041) 12457 1307.4 0
XP_016883951 (OMIM: 602259) PREDICTED: E3 ubiquiti (2041) 12457 1307.4 0
XP_016883948 (OMIM: 602259) PREDICTED: E3 ubiquiti (2063) 12457 1307.4 0
XP_011528042 (OMIM: 602259) PREDICTED: E3 ubiquiti (1792) 11963 1256.1 0
NP_001317610 (OMIM: 602259) E3 ubiquitin-protein l (1715) 11434 1201.2 0
NP_001317611 (OMIM: 602259) E3 ubiquitin-protein l (1715) 11434 1201.2 0
XP_016883954 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 6822 723.1 6.4e-207
XP_005261113 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 6822 723.1 6.4e-207
XP_005261112 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 6822 723.1 6.4e-207
XP_016883953 (OMIM: 602259) PREDICTED: E3 ubiquiti (1782) 6822 723.1 6.5e-207
XP_011528041 (OMIM: 602259) PREDICTED: E3 ubiquiti (1810) 6822 723.1 6.6e-207
XP_005261109 (OMIM: 602259) PREDICTED: E3 ubiquiti (2043) 6822 723.1 7.2e-207
NP_001307633 (OMIM: 602259) E3 ubiquitin-protein l (2043) 6822 723.1 7.2e-207
XP_005261111 (OMIM: 602259) PREDICTED: E3 ubiquiti (2043) 6822 723.1 7.2e-207
XP_005261107 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 6822 723.2 7.2e-207
XP_005261105 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 6822 723.2 7.2e-207
XP_005261106 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 6822 723.2 7.2e-207
NP_001307632 (OMIM: 602259) E3 ubiquitin-protein l (2065) 6822 723.2 7.3e-207
XP_016883947 (OMIM: 602259) PREDICTED: E3 ubiquiti (2081) 6822 723.2 7.3e-207
XP_011528044 (OMIM: 602259) PREDICTED: E3 ubiquiti (1059) 5635 599.8 5e-170
XP_005247976 (OMIM: 608672) PREDICTED: E3 ubiquiti (1002) 333 50.1 0.00015
XP_016863029 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
XP_005247974 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
XP_005247972 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
NP_055463 (OMIM: 608672) E3 ubiquitin-protein liga (1208) 333 50.2 0.00017
XP_005247973 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
XP_005247975 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
XP_005247971 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 333 50.2 0.00017
>>NP_001001894 (OMIM: 602259) E3 ubiquitin-protein ligas (2025 aa)
initn: 13556 init1: 13556 opt: 13556 Z-score: 7608.2 bits: 1421.3 E(85289): 0
Smith-Waterman score: 13556; 100.0% identity (100.0% similar) in 2025 aa overlap (1-2025:1-2025)
10 20 30 40 50 60
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE3 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020
pF1KE3 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
1990 2000 2010 2020
>>NP_003307 (OMIM: 602259) E3 ubiquitin-protein ligase T (2025 aa)
initn: 13556 init1: 13556 opt: 13556 Z-score: 7608.2 bits: 1421.3 E(85289): 0
Smith-Waterman score: 13556; 100.0% identity (100.0% similar) in 2025 aa overlap (1-2025:1-2025)
10 20 30 40 50 60
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE3 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020
pF1KE3 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
:::::::::::::::::::::::::::::::::::::::::::::
NP_003 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
1990 2000 2010 2020
>>NP_001317612 (OMIM: 602259) E3 ubiquitin-protein ligas (2025 aa)
initn: 13556 init1: 13556 opt: 13556 Z-score: 7608.2 bits: 1421.3 E(85289): 0
Smith-Waterman score: 13556; 100.0% identity (100.0% similar) in 2025 aa overlap (1-2025:1-2025)
10 20 30 40 50 60
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTY
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPV
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE3 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHK
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020
pF1KE3 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR
1990 2000 2010 2020
>>XP_016883949 (OMIM: 602259) PREDICTED: E3 ubiquitin-pr (2047 aa)
initn: 13556 init1: 13556 opt: 13556 Z-score: 7608.2 bits: 1421.3 E(85289): 0
Smith-Waterman score: 13556; 100.0% identity (100.0% similar) in 2025 aa overlap (1-2025:23-2047)
10 20 30
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYV
::::::::::::::::::::::::::::::::::::::
XP_016 MPGERGLPHPLRGCVVSVDLCTMDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 RVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 NSSVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKI
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 ENKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 LKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 GQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 LIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKI
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 NHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE3 TLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLN
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE3 GLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE3 YCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE3 EECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTT
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE3 TFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE3 SLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDD
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE3 RILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLI
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE3 QENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMT
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE3 FLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMD
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE3 SRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSN
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KE3 RNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFL
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KE3 EEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRL
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KE3 KKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPK
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KE3 PVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKP
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KE3 VLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPE
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KE3 YQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSH
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KE3 CSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVN
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 TEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEEN
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 KISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEH
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 ELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQI
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 MESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNG
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE3 SRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFS
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE3 AGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQ
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KE3 SPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQ
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KE3 KKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCE
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KE3 ICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQE
1990 2000 2010 2020 2030 2040
2020
pF1KE3 LPSCSSR
:::::::
XP_016 LPSCSSR
>>XP_016883950 (OMIM: 602259) PREDICTED: E3 ubiquitin-pr (2041 aa)
initn: 12457 init1: 12457 opt: 12457 Z-score: 6992.4 bits: 1307.4 E(85289): 0
Smith-Waterman score: 13514; 99.2% identity (99.2% similar) in 2041 aa overlap (1-2025:1-2041)
10 20 30 40 50 60
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
70 80 90 100 110 120
130 140 150 160
pF1KE3 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIEN----------------KILA
:::::::::::::::::::::::::::::::::::::::: ::::
XP_016 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENIIYLAYVSPNEIIRPLKILA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 MEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 MDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 LGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 KLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMAN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 GGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 KNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 IKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 VYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 PVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKI
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 DKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLR
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 LKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCI
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 KQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRV
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 KTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEK
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 YGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 RKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSA
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 GPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPL
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKK
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 KNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANS
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 PKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVK
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 PTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRS
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KE3 VPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDA
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE3 HTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNP
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE3 FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTE
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KE3 LDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQ
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KE3 SLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KE3 AFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSEL
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KE3 SKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPG
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KE3 EAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPF
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KE3 NSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPN
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KE3 PGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVF
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KE3 KSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSS
1990 2000 2010 2020 2030 2040
pF1KE3 R
:
XP_016 R
>>XP_016883951 (OMIM: 602259) PREDICTED: E3 ubiquitin-pr (2041 aa)
initn: 12457 init1: 12457 opt: 12457 Z-score: 6992.4 bits: 1307.4 E(85289): 0
Smith-Waterman score: 13514; 99.2% identity (99.2% similar) in 2041 aa overlap (1-2025:1-2041)
10 20 30 40 50 60
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEI
70 80 90 100 110 120
130 140 150 160
pF1KE3 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIEN----------------KILA
:::::::::::::::::::::::::::::::::::::::: ::::
XP_016 NLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENIIYLAYVSPNEIIRPLKILA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 MEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSC
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 MDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 LGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 KLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMAN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 GGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 KNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 IKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 VYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 PVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKI
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 DKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLR
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 LKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCI
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 KQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRV
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 KTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEK
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 YGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 RKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSA
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 GPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPL
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKK
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 KNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANS
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 PKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVK
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 PTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRS
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KE3 VPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDA
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE3 HTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNP
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE3 FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTE
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KE3 LDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQ
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KE3 SLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KE3 AFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSEL
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KE3 SKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPG
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KE3 EAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPF
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KE3 NSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPN
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KE3 PGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVF
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KE3 KSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSS
1990 2000 2010 2020 2030 2040
pF1KE3 R
:
XP_016 R
>>XP_016883948 (OMIM: 602259) PREDICTED: E3 ubiquitin-pr (2063 aa)
initn: 12457 init1: 12457 opt: 12457 Z-score: 6992.3 bits: 1307.4 E(85289): 0
Smith-Waterman score: 13514; 99.2% identity (99.2% similar) in 2041 aa overlap (1-2025:23-2063)
10 20 30
pF1KE3 MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYV
::::::::::::::::::::::::::::::::::::::
XP_016 MPGERGLPHPLRGCVVSVDLCTMDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 RVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 NSSVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKI
130 140 150 160 170 180
160 170 180 190 200
pF1KE3 EN----------------KILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYK
:: ::::::::::::::::::::::::::::::::::::::::::
XP_016 ENIIYLAYVSPNEIIRPLKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE3 YHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE3 ENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQAN
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE3 IKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIF
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE3 TTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQ
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE3 KSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALL
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE3 EQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQF
550 560 570 580 590 600
570 580 590 600 610 620
pF1KE3 KRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVII
610 620 630 640 650 660
630 640 650 660 670 680
pF1KE3 EESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQY
670 680 690 700 710 720
690 700 710 720 730 740
pF1KE3 CKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KE3 IKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEE
790 800 810 820 830 840
810 820 830 840 850 860
pF1KE3 QKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSS
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE3 RNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFF
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE3 SRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDK
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE3 FPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTS
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE3 VTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMN
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 PKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRF
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE3 VVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKP
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE3 VSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPG
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE3 SEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGL
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KE3 PQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIAS
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KE3 ETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQ
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KE3 MVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLE
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KE3 ETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSN
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KE3 ASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEV
1630 1640 1650 1660 1670 1680
1650 1660 1670 1680 1690 1700
pF1KE3 SVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIE
1690 1700 1710 1720 1730 1740
1710 1720 1730 1740 1750 1760
pF1KE3 KAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASD
1750 1760 1770 1780 1790 1800
1770 1780 1790 1800 1810 1820
pF1KE3 VTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVA
1810 1820 1830 1840 1850 1860
1830 1840 1850 1860 1870 1880
pF1KE3 DRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLS
1870 1880 1890 1900 1910 1920
1890 1900 1910 1920 1930 1940
pF1KE3 IDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQK
1930 1940 1950 1960 1970 1980
1950 1960 1970 1980 1990 2000
pF1KE3 AEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLL
1990 2000 2010 2020 2030 2040
2010 2020
pF1KE3 TEESPSGRGWPSQNQELPSCSSR
:::::::::::::::::::::::
XP_016 TEESPSGRGWPSQNQELPSCSSR
2050 2060
>>XP_011528042 (OMIM: 602259) PREDICTED: E3 ubiquitin-pr (1792 aa)
initn: 11963 init1: 11963 opt: 11963 Z-score: 6716.3 bits: 1256.1 E(85289): 0
Smith-Waterman score: 11963; 100.0% identity (100.0% similar) in 1792 aa overlap (234-2025:1-1792)
210 220 230 240 250 260
pF1KE3 HITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPE
::::::::::::::::::::::::::::::
XP_011 MKMKGNEEFSKERFDIAIIYYTRAIEYRPE
10 20 30
270 280 290 300 310 320
pF1KE3 NYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANI
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE3 KAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFT
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE3 TSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQK
160 170 180 190 200 210
450 460 470 480 490 500
pF1KE3 SRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLE
220 230 240 250 260 270
510 520 530 540 550 560
pF1KE3 QRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFK
280 290 300 310 320 330
570 580 590 600 610 620
pF1KE3 RIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIE
340 350 360 370 380 390
630 640 650 660 670 680
pF1KE3 ESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYC
400 410 420 430 440 450
690 700 710 720 730 740
pF1KE3 KIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVI
460 470 480 490 500 510
750 760 770 780 790 800
pF1KE3 KEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQ
520 530 540 550 560 570
810 820 830 840 850 860
pF1KE3 KETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSR
580 590 600 610 620 630
870 880 890 900 910 920
pF1KE3 NFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFS
640 650 660 670 680 690
930 940 950 960 970 980
pF1KE3 RYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKF
700 710 720 730 740 750
990 1000 1010 1020 1030 1040
pF1KE3 PALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSV
760 770 780 790 800 810
1050 1060 1070 1080 1090 1100
pF1KE3 TSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNP
820 830 840 850 860 870
1110 1120 1130 1140 1150 1160
pF1KE3 KQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFV
880 890 900 910 920 930
1170 1180 1190 1200 1210 1220
pF1KE3 VIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPV
940 950 960 970 980 990
1230 1240 1250 1260 1270 1280
pF1KE3 SDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGS
1000 1010 1020 1030 1040 1050
1290 1300 1310 1320 1330 1340
pF1KE3 EDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLP
1060 1070 1080 1090 1100 1110
1350 1360 1370 1380 1390 1400
pF1KE3 QYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASE
1120 1130 1140 1150 1160 1170
1410 1420 1430 1440 1450 1460
pF1KE3 TQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQM
1180 1190 1200 1210 1220 1230
1470 1480 1490 1500 1510 1520
pF1KE3 VAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEE
1240 1250 1260 1270 1280 1290
1530 1540 1550 1560 1570 1580
pF1KE3 TRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNA
1300 1310 1320 1330 1340 1350
1590 1600 1610 1620 1630 1640
pF1KE3 SEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVS
1360 1370 1380 1390 1400 1410
1650 1660 1670 1680 1690 1700
pF1KE3 VLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEK
1420 1430 1440 1450 1460 1470
1710 1720 1730 1740 1750 1760
pF1KE3 AKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDV
1480 1490 1500 1510 1520 1530
1770 1780 1790 1800 1810 1820
pF1KE3 TGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVAD
1540 1550 1560 1570 1580 1590
1830 1840 1850 1860 1870 1880
pF1KE3 RKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSI
1600 1610 1620 1630 1640 1650
1890 1900 1910 1920 1930 1940
pF1KE3 DEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKA
1660 1670 1680 1690 1700 1710
1950 1960 1970 1980 1990 2000
pF1KE3 EDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLT
1720 1730 1740 1750 1760 1770
2010 2020
pF1KE3 EESPSGRGWPSQNQELPSCSSR
::::::::::::::::::::::
XP_011 EESPSGRGWPSQNQELPSCSSR
1780 1790
>>NP_001317610 (OMIM: 602259) E3 ubiquitin-protein ligas (1715 aa)
initn: 11434 init1: 11434 opt: 11434 Z-score: 6420.1 bits: 1201.2 E(85289): 0
Smith-Waterman score: 11434; 100.0% identity (100.0% similar) in 1715 aa overlap (311-2025:1-1715)
290 300 310 320 330 340
pF1KE3 FRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLI
::::::::::::::::::::::::::::::
NP_001 MLGEYDWALQANIKAQKLCKNDPEGIKDLI
10 20 30
350 360 370 380 390 400
pF1KE3 QQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
40 50 60 70 80 90
410 420 430 440 450 460
pF1KE3 EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTL
100 110 120 130 140 150
470 480 490 500 510 520
pF1KE3 PADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGL
160 170 180 190 200 210
530 540 550 560 570 580
pF1KE3 DPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYC
220 230 240 250 260 270
590 600 610 620 630 640
pF1KE3 GIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEE
280 290 300 310 320 330
650 660 670 680 690 700
pF1KE3 CKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
340 350 360 370 380 390
710 720 730 740 750 760
pF1KE3 NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSL
400 410 420 430 440 450
770 780 790 800 810 820
pF1KE3 EKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRI
460 470 480 490 500 510
830 840 850 860 870 880
pF1KE3 LQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQE
520 530 540 550 560 570
890 900 910 920 930 940
pF1KE3 NNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFL
580 590 600 610 620 630
950 960 970 980 990 1000
pF1KE3 WNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSR
640 650 660 670 680 690
1010 1020 1030 1040 1050 1060
pF1KE3 CTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRN
700 710 720 730 740 750
1070 1080 1090 1100 1110 1120
pF1KE3 SDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEE
760 770 780 790 800 810
1130 1140 1150 1160 1170 1180
pF1KE3 HGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKK
820 830 840 850 860 870
1190 1200 1210 1220 1230 1240
pF1KE3 KRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPV
880 890 900 910 920 930
1250 1260 1270 1280 1290 1300
pF1KE3 SANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVL
940 950 960 970 980 990
1310 1320 1330 1340 1350 1360
pF1KE3 EDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQ
1000 1010 1020 1030 1040 1050
1370 1380 1390 1400 1410 1420
pF1KE3 LPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCS
1060 1070 1080 1090 1100 1110
1430 1440 1450 1460 1470 1480
pF1KE3 TGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTE
1120 1130 1140 1150 1160 1170
1490 1500 1510 1520 1530 1540
pF1KE3 PYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKI
1180 1190 1200 1210 1220 1230
1550 1560 1570 1580 1590 1600
pF1KE3 SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL
1240 1250 1260 1270 1280 1290
1610 1620 1630 1640 1650 1660
pF1KE3 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIME
1300 1310 1320 1330 1340 1350
1670 1680 1690 1700 1710 1720
pF1KE3 SQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR
1360 1370 1380 1390 1400 1410
1730 1740 1750 1760 1770 1780
pF1KE3 LSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAG
1420 1430 1440 1450 1460 1470
1790 1800 1810 1820 1830 1840
pF1KE3 DSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSP
1480 1490 1500 1510 1520 1530
1850 1860 1870 1880 1890 1900
pF1KE3 KKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKK
1540 1550 1560 1570 1580 1590
1910 1920 1930 1940 1950 1960
pF1KE3 KKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEIC
1600 1610 1620 1630 1640 1650
1970 1980 1990 2000 2010 2020
pF1KE3 HEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELP
1660 1670 1680 1690 1700 1710
pF1KE3 SCSSR
:::::
NP_001 SCSSR
>>NP_001317611 (OMIM: 602259) E3 ubiquitin-protein ligas (1715 aa)
initn: 11434 init1: 11434 opt: 11434 Z-score: 6420.1 bits: 1201.2 E(85289): 0
Smith-Waterman score: 11434; 100.0% identity (100.0% similar) in 1715 aa overlap (311-2025:1-1715)
290 300 310 320 330 340
pF1KE3 FRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLI
::::::::::::::::::::::::::::::
NP_001 MLGEYDWALQANIKAQKLCKNDPEGIKDLI
10 20 30
350 360 370 380 390 400
pF1KE3 QQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINH
40 50 60 70 80 90
410 420 430 440 450 460
pF1KE3 EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTL
100 110 120 130 140 150
470 480 490 500 510 520
pF1KE3 PADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGL
160 170 180 190 200 210
530 540 550 560 570 580
pF1KE3 DPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYC
220 230 240 250 260 270
590 600 610 620 630 640
pF1KE3 GIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEE
280 290 300 310 320 330
650 660 670 680 690 700
pF1KE3 CKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTF
340 350 360 370 380 390
710 720 730 740 750 760
pF1KE3 NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSL
400 410 420 430 440 450
770 780 790 800 810 820
pF1KE3 EKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRI
460 470 480 490 500 510
830 840 850 860 870 880
pF1KE3 LQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQE
520 530 540 550 560 570
890 900 910 920 930 940
pF1KE3 NNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFL
580 590 600 610 620 630
950 960 970 980 990 1000
pF1KE3 WNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSR
640 650 660 670 680 690
1010 1020 1030 1040 1050 1060
pF1KE3 CTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRN
700 710 720 730 740 750
1070 1080 1090 1100 1110 1120
pF1KE3 SDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEE
760 770 780 790 800 810
1130 1140 1150 1160 1170 1180
pF1KE3 HGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKK
820 830 840 850 860 870
1190 1200 1210 1220 1230 1240
pF1KE3 KRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPV
880 890 900 910 920 930
1250 1260 1270 1280 1290 1300
pF1KE3 SANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVL
940 950 960 970 980 990
1310 1320 1330 1340 1350 1360
pF1KE3 EDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQ
1000 1010 1020 1030 1040 1050
1370 1380 1390 1400 1410 1420
pF1KE3 LPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCS
1060 1070 1080 1090 1100 1110
1430 1440 1450 1460 1470 1480
pF1KE3 TGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTE
1120 1130 1140 1150 1160 1170
1490 1500 1510 1520 1530 1540
pF1KE3 PYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKI
1180 1190 1200 1210 1220 1230
1550 1560 1570 1580 1590 1600
pF1KE3 SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHEL
1240 1250 1260 1270 1280 1290
1610 1620 1630 1640 1650 1660
pF1KE3 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIME
1300 1310 1320 1330 1340 1350
1670 1680 1690 1700 1710 1720
pF1KE3 SQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSR
1360 1370 1380 1390 1400 1410
1730 1740 1750 1760 1770 1780
pF1KE3 LSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAG
1420 1430 1440 1450 1460 1470
1790 1800 1810 1820 1830 1840
pF1KE3 DSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSP
1480 1490 1500 1510 1520 1530
1850 1860 1870 1880 1890 1900
pF1KE3 KKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKK
1540 1550 1560 1570 1580 1590
1910 1920 1930 1940 1950 1960
pF1KE3 KKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEIC
1600 1610 1620 1630 1640 1650
1970 1980 1990 2000 2010 2020
pF1KE3 HEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELP
1660 1670 1680 1690 1700 1710
pF1KE3 SCSSR
:::::
NP_001 SCSSR
2025 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:21:27 2016 done: Mon Nov 7 15:21:29 2016
Total Scan time: 18.080 Total Display time: 1.270
Function used was FASTA [36.3.4 Apr, 2011]