Result of FASTA (omim) for
pFN21AE3711
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3711, 359 aa
1>>>pF1KE3711 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2578+/-0.000302; mu= 17.6449+/- 0.019
mean_var=220.3158+/-45.175, 0's: 0 Z-trim(124.5): 55 B-trim: 745 in 1/56
Lambda= 0.086407
statistics sampled from 46295 (46361) to 46295 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.544), width: 16
Scan time: 10.300
The best scores are: opt bits E(85289)
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 2518 325.8 9.3e-89
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 2413 312.7 8.1e-85
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 1461 193.8 3.6e-49
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 1251 167.4 2.3e-41
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 1251 167.4 2.3e-41
NP_001272915 (OMIM: 164177) POU domain, class 5, t ( 164) 1086 146.8 3.3e-35
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 666 95.1 3.5e-19
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 639 91.7 3.4e-18
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 634 90.9 4.7e-18
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 635 91.2 4.8e-18
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 559 82.0 4.3e-15
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 559 82.0 4.4e-15
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 559 82.1 4.5e-15
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 559 82.1 4.5e-15
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 559 82.1 4.6e-15
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 559 82.1 4.6e-15
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 532 78.3 3.3e-14
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 532 78.3 3.3e-14
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 532 78.3 3.3e-14
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 531 78.1 3.4e-14
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 532 78.3 3.5e-14
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 532 78.3 3.5e-14
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 532 78.3 3.5e-14
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 532 78.3 3.5e-14
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 489 73.0 1.4e-12
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 463 69.5 1.1e-11
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 463 69.5 1.1e-11
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 431 65.6 1.9e-10
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 427 65.2 2.9e-10
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 393 61.1 5.9e-09
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 393 61.1 6e-09
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 393 61.1 6.2e-09
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 393 61.2 6.8e-09
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 393 61.2 6.8e-09
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 393 61.2 6.8e-09
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 393 61.3 6.9e-09
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 393 61.3 7.4e-09
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 393 61.3 7.4e-09
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 393 61.3 7.4e-09
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 393 61.3 7.4e-09
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 393 61.3 7.4e-09
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 393 61.3 7.4e-09
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 393 61.4 7.5e-09
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 393 61.4 7.5e-09
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 388 60.5 9.9e-09
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 388 60.7 1.1e-08
XP_016856997 (OMIM: 164175) PREDICTED: POU domain, ( 381) 353 55.9 1.7e-07
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 350 55.7 2.4e-07
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 350 55.7 2.5e-07
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 350 55.9 2.8e-07
>>NP_001153014 (OMIM: 615739) putative POU domain, class (359 aa)
initn: 2518 init1: 2518 opt: 2518 Z-score: 1714.5 bits: 325.8 E(85289): 9.3e-89
Smith-Waterman score: 2518; 99.4% identity (99.7% similar) in 359 aa overlap (1-359:1-359)
10 20 30 40 50 60
pF1KE3 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNDENLQEICKAETLMQARKRKRTSIENR
: :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
310 320 330 340 350
>>NP_002692 (OMIM: 164177) POU domain, class 5, transcri (360 aa)
initn: 1735 init1: 1735 opt: 2413 Z-score: 1643.7 bits: 312.7 E(85289): 8.1e-85
Smith-Waterman score: 2413; 95.8% identity (97.8% similar) in 360 aa overlap (1-359:1-360)
10 20 30 40 50 60
pF1KE3 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
:::::::::::::::::::::: : ::::::: :::::::::::::::::::::::::::
NP_002 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
::::::::.:::::::::::::::::::::::::::.::::::::::.::::::::: ::
NP_002 PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
::::::::::::::.:::::::::::::::::::::::::::::::::: ::::::::::
NP_002 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNDENLQEICKAETLMQARKRKRTSIENR
:::::::::::::::::::::::::::::::::.::::::::::::.:::::::::::::
NP_002 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 VRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_002 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 AGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
::::::::::::: :::::::::::::::::::::::::::::.:::::: :::::::::
NP_002 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
310 320 330 340 350 360
>>NP_001272916 (OMIM: 164177) POU domain, class 5, trans (265 aa)
initn: 783 init1: 783 opt: 1461 Z-score: 1003.6 bits: 193.8 E(85289): 3.6e-49
Smith-Waterman score: 1461; 96.5% identity (98.2% similar) in 226 aa overlap (135-359:40-265)
110 120 130 140 150 160
pF1KE3 SNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQ
.:::::::::::::::::::::::::::::
NP_001 ATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQ
10 20 30 40 50 60
170 180 190 200 210 220
pF1KE3 ADVGLILGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNDENLQEICKAE
::::: :::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 ADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAE
70 80 90 100 110 120
230 240 250 260 270 280
pF1KE3 TLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQK
::.::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 TLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQK
130 140 150 160 170 180
290 300 310 320 330 340
pF1KE3 GKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEV
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::.
NP_001 GKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEA
190 200 210 220 230 240
350
pF1KE3 FPPVSVITLGSPMHSN
:::::: :::::::::
NP_001 FPPVSVTTLGSPMHSN
250 260
>>NP_976034 (OMIM: 164177) POU domain, class 5, transcri (190 aa)
initn: 697 init1: 697 opt: 1251 Z-score: 863.6 bits: 167.4 E(85289): 2.3e-41
Smith-Waterman score: 1251; 96.3% identity (98.4% similar) in 190 aa overlap (171-359:1-190)
150 160 170 180 190 200
pF1KE3 ALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRFEALQLSFKNMCKL
.:::::::::::::::::::::::::::::
NP_976 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
210 220 230 240 250
pF1KE3 RPLLQKWVEEADNDENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ-I
:::::::::::::.::::::::::::.::::::::::::::::::::::::::::::: :
NP_976 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE3 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_976 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
100 110 120 130 140 150
320 330 340 350
pF1KE3 GTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
:::::::::::::::::::::::.:::::: :::::::::
NP_976 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
160 170 180 190
>>NP_001167002 (OMIM: 164177) POU domain, class 5, trans (190 aa)
initn: 697 init1: 697 opt: 1251 Z-score: 863.6 bits: 167.4 E(85289): 2.3e-41
Smith-Waterman score: 1251; 96.3% identity (98.4% similar) in 190 aa overlap (171-359:1-190)
150 160 170 180 190 200
pF1KE3 ALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRFEALQLSFKNMCKL
.:::::::::::::::::::::::::::::
NP_001 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
210 220 230 240 250
pF1KE3 RPLLQKWVEEADNDENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ-I
:::::::::::::.::::::::::::.::::::::::::::::::::::::::::::: :
NP_001 RPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE3 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_001 SHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHF
100 110 120 130 140 150
320 330 340 350
pF1KE3 GTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
:::::::::::::::::::::::.:::::: :::::::::
NP_001 GTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
160 170 180 190
>>NP_001272915 (OMIM: 164177) POU domain, class 5, trans (164 aa)
initn: 697 init1: 697 opt: 1086 Z-score: 753.0 bits: 146.8 E(85289): 3.3e-35
Smith-Waterman score: 1086; 96.3% identity (98.2% similar) in 164 aa overlap (197-359:1-164)
170 180 190 200 210 220
pF1KE3 VGLILGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNDENLQEICKAETL
:::::::::::::::::.::::::::::::
NP_001 MCKLRPLLQKWVEEADNNENLQEICKAETL
10 20 30
230 240 250 260 270 280
pF1KE3 MQARKRKRTSIENRVRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGK
.::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_001 VQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGK
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE3 RSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFP
::::::::::::::::::::::::::: :::::::::::::::::::::::::::::.::
NP_001 RSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFP
100 110 120 130 140 150
350
pF1KE3 PVSVITLGSPMHSN
:::: :::::::::
NP_001 PVSVTTLGSPMHSN
160
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 695 init1: 477 opt: 666 Z-score: 465.4 bits: 95.1 E(85289): 3.5e-19
Smith-Waterman score: 686; 43.3% identity (60.7% similar) in 328 aa overlap (13-320:177-494)
10 20 30
pF1KE3 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVD-----------
::: : : ::: . .
NP_006 PDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHL
150 160 170 180 190 200
40 50 60 70 80 90
pF1KE3 PLTWLSFQGPPGGPGIG-PGVGPGSEVWGIPPCPPPYELCGGMAYCGPQVGVGLVPQGGL
: . : :: . . :: : : :. :: :: : : : .:: : .
NP_006 PSMAGGQQPPPQSLLYSQPG---GFTVNGMLSAPPGPGGGGGGAGGGAQ---SLVHPGLV
210 220 230 240 250 260
100 110 120 130 140
pF1KE3 ETSQPE-SEAGVGVESNSNGASPEPCTV--PP---GAVKLEKEKLEQNPEKSQDIKALQK
. . :: .: . ... :.: . :: :. :... .:.. .
NP_006 RGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSD
270 280 290 300 310 320
150 160 170 180 190 200
pF1KE3 ELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL
.:::::: .::.:: ::.::::::: ::.:.:.:::::::::::::::::::::::.:::
NP_006 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL
330 340 350 360 370 380
210 220 230 240 250 260
pF1KE3 QKWVEEADNDENLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCPKPTLQ-ISHI
.::.::::.. . . . :.:::: ::::: :.: ::. ::.::::. : :...
NP_006 NKWLEEADSSTG-SPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNL
390 400 410 420 430
270 280 290 300 310 320
pF1KE3 AQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTP
:..: :::.:::::::::::: :: . :.. . . : : :: .: :: :
NP_006 ADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQV--GTVS-ADTPPPHHGLQ
440 450 460 470 480 490
330 340 350
pF1KE3 GYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
NP_006 TSVQ
500
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 672 init1: 465 opt: 639 Z-score: 447.6 bits: 91.7 E(85289): 3.4e-18
Smith-Waterman score: 689; 43.4% identity (60.3% similar) in 343 aa overlap (2-317:134-435)
10 20
pF1KE3 MAGHLASDFAFSPPPGG-GGDGPW-------
: ::. :.:: ::. :: :
NP_002 DDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGP--AMSPSPGASGGHQPQPLGLYAQ
110 120 130 140 150 160
30 40 50 60 70
pF1KE3 GAEPGWVDPLTWLSFQGPPGGPGIGPGVG-----PGSEVWGIPPCPPPYELCGGMAYCGP
.: :: :. . :: : :::. : :. . : :::. : :.
NP_002 AAYPG--GGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQ-LEPSPPPHLGAHGHAH---
170 180 190 200 210
80 90 100 110 120 130
pF1KE3 QVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQD
: . :::... . . :.: ..: : :. ... .:.:
NP_002 ----GHAHAGGLHAAAAHLHPGAGGGGSSVG-----------------EHSDEDAPSSDD
220 230 240 250
140 150 160 170 180 190
pF1KE3 IKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRFEALQLSFKNMC
:::::: .::.:: ::.::::::: ::.:.:.:::::::::::::::::::::
NP_002 -------LEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMC
260 270 280 290 300
200 210 220 230 240 250
pF1KE3 KLRPLLQKWVEEADNDE----NLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCP
::.:::.::.::.:.. ::..: :.:::: ::::: :.: ::. ::.::
NP_002 KLKPLLNKWLEETDSSSGSPTNLDKIAA-----QGRKRKKRTSIEVGVKGALESHFLKCP
310 320 330 340 350 360
260 270 280 290 300
pF1KE3 KPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFEAAG--SPFSG
::. .:. .:..: :::.:::::::::::: :: ... . .: : : .: .:
NP_002 KPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGG
370 380 390 400 410 420
310 320 330 340 350
pF1KE3 G--PVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
: : : :: : :
NP_002 GASPPSAPPPPPPAALHHHHHHTLPGSVQ
430 440 450
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 629 init1: 478 opt: 634 Z-score: 445.2 bits: 90.9 E(85289): 4.7e-18
Smith-Waterman score: 650; 49.2% identity (68.0% similar) in 244 aa overlap (58-294:114-343)
30 40 50 60 70 80
pF1KE3 GWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYELCGGM---AYCGPQVGV-G
:: : : : .:. .: : : :
NP_000 GREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNPSITSSGQPLNVYSQPGFTVSG
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE3 LVPQGGLETSQPESEAGVGVESNSNGASPEPCTV-PPGAVKLEKEKLEQNPEKSQDIKAL
.. .::: . : . : .. : .: :: .: ... . ..:..
NP_000 MLEHGGL--TPPPAAA--------SAQSLHPVLREPPDHGELGSHHCQ---DHSDEETPT
150 160 170 180 190
150 160 170 180 190 200
pF1KE3 QKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRFEALQLSFKNMCKLRP
. ::::::: .::.:: ::.::::::: ::.:.:.:::::::::::::::::::::::.:
NP_000 SDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKP
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE3 LLQKWVEEADNDENLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCPKPTLQ-IS
::.::.::::.. . . . :.:::: ::::: :.: ::. ::.::::. : ::
NP_000 LLNKWLEEADSSTG-SPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEIS
260 270 280 290 300
270 280 290 300 310 320
pF1KE3 HIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFG
.:..: :::.:::::::::::: :: . :.
NP_000 SLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDTSCHDL
310 320 330 340 350 360
330 340 350
pF1KE3 TPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 719 init1: 479 opt: 635 Z-score: 445.0 bits: 91.2 E(85289): 4.8e-18
Smith-Waterman score: 650; 43.8% identity (62.6% similar) in 281 aa overlap (49-316:163-437)
20 30 40 50 60 70
pF1KE3 GDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYELC-GGMAYCG
:: : . . :: . ::. :
NP_005 QQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQ
140 150 160 170 180 190
80 90 100 110 120
pF1KE3 PQ------VGVGLVPQG----GLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKE
:. .:.: : : ::. .. : . . . .: :: .
NP_005 PSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPGHP
200 210 220 230 240 250
130 140 150 160 170 180
pF1KE3 KLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQTTICRF
...:....: . . .:::::: .::.:: ::.::::::: ::.:.:.::::::::::
NP_005 GAHHDPHSDEDTPT-SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRF
260 270 280 290 300 310
190 200 210 220 230 240
pF1KE3 EALQLSFKNMCKLRPLLQKWVEEADNDENLQEICKAETLMQARKRK-RTSIENRVRGNLE
:::::::::::::.:::.::.::::.. . . . :.:::: ::::: :.: ::
NP_005 EALQLSFKNMCKLKPLLNKWLEEADSSSG-SPTSIDKIAAQGRKRKKRTSIEVSVKGALE
320 330 340 350 360 370
250 260 270 280 290 300
pF1KE3 NLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFS
. ::.::::. : :. .:..: :::.:::::::::::: :: . . : .
NP_005 SHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDV----Y
380 390 400 410 420
310 320 330 340 350
pF1KE3 GGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
:: . :: :
NP_005 GGSRDTPPHHGVQTPVQ
430 440
359 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:43:40 2016 done: Tue Nov 8 07:43:42 2016
Total Scan time: 10.300 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]