Result of FASTA (omim) for
pFN21AE3681
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3681, 363 aa
1>>>pF1KE3681 363 - 363 aa - 363 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6822+/-0.000317; mu= 20.0969+/- 0.020
mean_var=191.8192+/-40.908, 0's: 0 Z-trim(122.2): 385 B-trim: 2162 in 1/53
Lambda= 0.092604
statistics sampled from 39348 (39832) to 39348 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.467), width: 16
Scan time: 8.220
The best scores are: opt bits E(85289)
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 2530 349.8 5.7e-96
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392) 2530 349.8 5.9e-96
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378) 2252 312.7 8.8e-85
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407) 2252 312.7 9.2e-85
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 2246 311.8 1.5e-84
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377) 2246 311.9 1.5e-84
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 1396 198.0 1.8e-50
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 1368 194.5 3.1e-49
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 1368 194.5 3.1e-49
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 1361 193.6 5.7e-49
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 1361 193.6 5.8e-49
NP_001229264 (OMIM: 608215) LIM/homeobox protein L ( 176) 1208 172.7 5.7e-43
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 475 75.3 2.6e-13
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 471 74.7 3.8e-13
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 469 74.5 4.5e-13
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 469 74.5 4.6e-13
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 451 71.9 2.2e-12
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 445 71.3 4.3e-12
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 436 70.0 9e-12
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 437 70.2 9e-12
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 436 70.1 9.5e-12
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 436 70.1 9.7e-12
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 436 70.1 9.8e-12
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 436 70.1 9.9e-12
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 428 69.0 2e-11
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 415 67.2 6.4e-11
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 411 66.7 9.4e-11
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 411 67.0 1.2e-10
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 392 64.0 4.8e-10
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 392 64.2 5.6e-10
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 392 64.2 5.6e-10
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 391 64.1 6.3e-10
NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 391 64.1 6.4e-10
NP_001167617 (OMIM: 161200,602575) LIM homeobox tr ( 406) 391 64.1 6.4e-10
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 382 62.3 9.2e-10
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 382 62.3 9.2e-10
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 349 57.8 1.8e-08
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 349 57.8 1.8e-08
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 349 57.8 1.9e-08
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 349 57.8 1.9e-08
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 349 58.0 2.1e-08
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 334 55.8 7.3e-08
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 334 55.8 7.3e-08
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 334 55.8 7.3e-08
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 334 55.8 7.3e-08
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 334 55.8 7.3e-08
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 334 55.8 7.3e-08
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 334 55.8 7.3e-08
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 334 55.8 7.3e-08
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 334 55.8 7.6e-08
>>NP_001229263 (OMIM: 608215) LIM/homeobox protein Lhx6 (363 aa)
initn: 2530 init1: 2530 opt: 2530 Z-score: 1844.0 bits: 349.8 E(85289): 5.7e-96
Smith-Waterman score: 2530; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 IHYTPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHYTPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVIL
310 320 330 340 350 360
pF1KE3 FQY
:::
NP_001 FQY
>>NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 iso (392 aa)
initn: 2530 init1: 2530 opt: 2530 Z-score: 1843.7 bits: 349.8 E(85289): 5.9e-96
Smith-Waterman score: 2530; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:30-392)
10 20 30
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
:::::::::::::::::::::::::::::::
NP_055 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVH
310 320 330 340 350 360
340 350 360
pF1KE3 CRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
::::::::::::::::::::::::::::::::
NP_055 CRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
370 380 390
>>XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobox pr (378 aa)
initn: 2262 init1: 2239 opt: 2252 Z-score: 1643.1 bits: 312.7 E(85289): 8.8e-85
Smith-Waterman score: 2252; 90.7% identity (93.7% similar) in 365 aa overlap (1-357:1-362)
10 20 30 40 50 60
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDD
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 IHYTPFSSPERARMVTLHGYIESQVQ--------CGQVHCRLPYTAPPVHLKADMDGPLS
::::::::::::::::::::::.... ::.. .: :: :. : .
XP_011 IHYTPFSSPERARMVTLHGYIETNARLLAGMCDWCGHLIWQLQRIIPPQSLHY---GAAN
310 320 330 340 350
360
pF1KE3 NRGEKVILFQY
: ..:
XP_011 NTADKAWMSPRASLQVIITFR
360 370
>>XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobox pr (407 aa)
initn: 2262 init1: 2239 opt: 2252 Z-score: 1642.8 bits: 312.7 E(85289): 9.2e-85
Smith-Waterman score: 2252; 90.7% identity (93.7% similar) in 365 aa overlap (1-357:30-391)
10 20 30
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
:::::::::::::::::::::::::::::::
XP_011 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
250 260 270 280 290 300
280 290 300 310 320
pF1KE3 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQ-----
:::::::::::::::::::::::::::::::::::::::::::::::::::....
XP_011 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIETNARLLAGM
310 320 330 340 350 360
330 340 350 360
pF1KE3 ---CGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
::.. .: :: :. : .: ..:
XP_011 CDWCGHLIWQLQRIIPPQSLHY---GAANNTADKAWMSPRASLQVIITFR
370 380 390 400
>>NP_001229262 (OMIM: 608215) LIM/homeobox protein Lhx6 (366 aa)
initn: 2242 init1: 2242 opt: 2246 Z-score: 1638.9 bits: 311.8 E(85289): 1.5e-84
Smith-Waterman score: 2246; 95.1% identity (96.2% similar) in 346 aa overlap (1-343:19-364)
10 20 30 40
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQA
::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRGLCRRSAENPDAGPVMAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 SPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 SLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSC
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 KRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 RTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHP
250 260 270 280 290 300
290 300 310 320 330
pF1KE3 VPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQ---VQCGQVHCRLPYTAP
:::::::::::::::::::::::::::::::::::::::::. : . .:: ::
NP_001 VPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESHPFSVLTLPALPHLPVGAP
310 320 330 340 350 360
340 350 360
pF1KE3 PVHLKADMDGPLSNRGEKVILFQY
. :
NP_001 QLPLSR
>>NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 iso (377 aa)
initn: 2242 init1: 2242 opt: 2246 Z-score: 1638.8 bits: 311.9 E(85289): 1.5e-84
Smith-Waterman score: 2246; 95.1% identity (96.2% similar) in 346 aa overlap (1-343:30-375)
10 20 30
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
:::::::::::::::::::::::::::::::
NP_954 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
250 260 270 280 290 300
280 290 300 310 320
pF1KE3 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQ---VQCG
::::::::::::::::::::::::::::::::::::::::::::::::::::. :
NP_954 ARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESHPFSVLTL
310 320 330 340 350 360
330 340 350 360
pF1KE3 QVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
. .:: :: . :
NP_954 PALPHLPVGAPQLPLSR
370
>>XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobox pr (230 aa)
initn: 1396 init1: 1396 opt: 1396 Z-score: 1027.1 bits: 198.0 E(85289): 1.8e-50
Smith-Waterman score: 1396; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:30-228)
10 20 30
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
:::::::::::::::::::::::::::::::
XP_005 MYWKHENAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEAL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGCH
190 200 210 220 230
220 230 240 250 260 270
pF1KE3 QDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCR
>>XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobox pr (363 aa)
initn: 1330 init1: 881 opt: 1368 Z-score: 1005.0 bits: 194.5 E(85289): 3.1e-49
Smith-Waterman score: 1368; 61.7% identity (80.8% similar) in 334 aa overlap (8-335:5-332)
10 20 30 40 50 60
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
: :: : . . .. . :: :.: . : .: .:: :: : ::
XP_016 MSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDED--SCSSSAPLSPS-SSPRSMAS
10 20 30 40 50
70 80 90 100 110
pF1KE3 -SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFC
: :: .:.::::::.:.::::::.: :::::: :::::::: ...:::::.:.:::
XP_016 GSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKV
:.::: :.::.:.::::.:...::::::.::.:::::::::::::::::::::.::::::
XP_016 KLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQF
:::.::: :..:::: .:::::...:::. .::: ..:::::::::::::.:::::::::
XP_016 LCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQHP--VPPSGAPPSRLPS
:::::::::::::::. :::::::::::::::::::::: .:.: .: ...:::::
XP_016 AQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 ALSDDIHYTPFSSPERARMVT-LHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNR
. ... :. . :. . :.: ::.:... . :: .::
XP_016 PMLEEMAYSAYV-PQDGTMLTALHSYMDDT--HAAVHIHLPGRMWRFQGYSNNGSSSGST
300 310 320 330 340 350
360
pF1KE3 GEKVILFQY
XP_016 LICKYNENIFLF
360
>>XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobox pr (363 aa)
initn: 1330 init1: 881 opt: 1368 Z-score: 1005.0 bits: 194.5 E(85289): 3.1e-49
Smith-Waterman score: 1368; 61.7% identity (80.8% similar) in 334 aa overlap (8-335:5-332)
10 20 30 40 50 60
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
: :: : . . .. . :: :.: . : .: .:: :: : ::
XP_016 MSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDED--SCSSSAPLSPS-SSPRSMAS
10 20 30 40 50
70 80 90 100 110
pF1KE3 -SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFC
: :: .:.::::::.:.::::::.: :::::: :::::::: ...:::::.:.:::
XP_016 GSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKV
:.::: :.::.:.::::.:...::::::.::.:::::::::::::::::::::.::::::
XP_016 KLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQF
:::.::: :..:::: .:::::...:::. .::: ..:::::::::::::.:::::::::
XP_016 LCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQHP--VPPSGAPPSRLPS
:::::::::::::::. :::::::::::::::::::::: .:.: .: ...:::::
XP_016 AQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 ALSDDIHYTPFSSPERARMVT-LHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNR
. ... :. . :. . :.: ::.:... . :: .::
XP_016 PMLEEMAYSAYV-PQDGTMLTALHSYMDDT--HAAVHIHLPGRMWRFQGYSNNGSSSGST
300 310 320 330 340 350
360
pF1KE3 GEKVILFQY
XP_016 LICKYNENIFLF
360
>>NP_001243043 (OMIM: 604425) LIM/homeobox protein Lhx8 (346 aa)
initn: 1332 init1: 881 opt: 1361 Z-score: 1000.1 bits: 193.6 E(85289): 5.7e-49
Smith-Waterman score: 1361; 62.5% identity (82.0% similar) in 323 aa overlap (8-324:5-323)
10 20 30 40 50 60
pF1KE3 MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAAS
: :: : . . .. . :: :.: . : .: .:: :: : ::
NP_001 MSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDED--SCSSSAPLSPS-SSPRSMAS
10 20 30 40 50
70 80 90 100 110
pF1KE3 -SVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFC
: :: .:.::::::.:.::::::.: :::::: :::::::: ...:::::.:.:::
NP_001 GSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKV
:.::: :.::.:.::::.:...::::::.::.:::::::::::::::::::::.::::::
NP_001 KLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQF
:::.::: :..:::: .:::::...:::. .::: ..:::::::::::::.:::::::::
NP_001 LCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQHP--VPPSGAPPSRLPS
:::::::::::::::. :::::::::::::::::::::: .:.: .: ...:::::
NP_001 AQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 ALSDDIHYTPFSSPERARMVT-LHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNR
. ... :. . :. . :.: ::.:....
NP_001 PMLEEMAYSAYV-PQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT
300 310 320 330 340
363 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:10:12 2016 done: Mon Nov 7 16:10:14 2016
Total Scan time: 8.220 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]