Result of FASTA (omim) for
pFN21AE3671
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3671, 970 aa
1>>>pF1KE3671 970 - 970 aa - 970 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2580+/-0.000629; mu= 3.4559+/- 0.038
mean_var=589.9584+/-136.814, 0's: 0 Z-trim(115.0): 1986 B-trim: 33 in 1/56
Lambda= 0.052804
statistics sampled from 22625 (25205) to 22625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.296), width: 16
Scan time: 13.860
The best scores are: opt bits E(85289)
NP_055079 (OMIM: 605031,616171) serine/threonine-p ( 970) 6431 507.2 1.6e-142
XP_016863151 (OMIM: 605031,616171) PREDICTED: seri ( 971) 6377 503.1 2.8e-141
NP_001177730 (OMIM: 605031,616171) serine/threonin ( 929) 6169 487.2 1.6e-136
NP_001177728 (OMIM: 605031,616171) serine/threonin ( 938) 5953 470.8 1.5e-131
XP_005262758 (OMIM: 605031,616171) PREDICTED: seri ( 936) 3468 281.5 1.4e-74
XP_016863152 (OMIM: 605031,616171) PREDICTED: seri ( 937) 3468 281.5 1.4e-74
NP_004064 (OMIM: 602913) serine/threonine-protein ( 646) 756 74.6 1.8e-12
NP_001239155 (OMIM: 607023) serine/threonine-prote ( 671) 731 72.7 7.1e-12
NP_006613 (OMIM: 607023) serine/threonine-protein ( 685) 731 72.8 7.1e-12
NP_005021 (OMIM: 602098) serine/threonine-protein ( 603) 687 69.3 6.8e-11
NP_001310233 (OMIM: 603072) aurora kinase A [Homo ( 403) 663 67.2 2e-10
NP_001310232 (OMIM: 603072) aurora kinase A [Homo ( 403) 663 67.2 2e-10
NP_940836 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
NP_001310234 (OMIM: 603072) aurora kinase A [Homo ( 403) 663 67.2 2e-10
NP_940839 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
NP_940835 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
NP_940838 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
XP_016883524 (OMIM: 603072) PREDICTED: aurora kina ( 403) 663 67.2 2e-10
NP_940837 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
NP_003591 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 663 67.2 2e-10
XP_016883523 (OMIM: 603072) PREDICTED: aurora kina ( 437) 663 67.2 2.1e-10
XP_016880796 (OMIM: 604970) PREDICTED: aurora kina ( 303) 636 64.9 7.2e-10
NP_001300880 (OMIM: 604970) aurora kinase B isofor ( 303) 636 64.9 7.2e-10
NP_001243763 (OMIM: 604970) aurora kinase B isofor ( 303) 636 64.9 7.2e-10
XP_011522374 (OMIM: 604970) PREDICTED: aurora kina ( 303) 636 64.9 7.2e-10
NP_001300881 (OMIM: 604970) aurora kinase B isofor ( 304) 636 64.9 7.2e-10
NP_004208 (OMIM: 604970) aurora kinase B isoform 1 ( 344) 636 65.0 7.7e-10
NP_001300879 (OMIM: 604970) aurora kinase B isofor ( 344) 636 65.0 7.7e-10
NP_001271455 (OMIM: 604970) aurora kinase B isofor ( 345) 636 65.0 7.7e-10
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661) 637 65.6 1e-09
NP_003151 (OMIM: 243060,603495) aurora kinase C is ( 275) 609 62.8 2.9e-09
NP_001015879 (OMIM: 243060,603495) aurora kinase C ( 290) 609 62.8 2.9e-09
NP_001015878 (OMIM: 243060,603495) aurora kinase C ( 309) 609 62.9 3e-09
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 605 63.1 5.4e-09
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 605 63.2 5.7e-09
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 605 63.2 5.7e-09
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 605 63.2 5.7e-09
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 605 63.2 5.8e-09
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 605 63.2 5.8e-09
NP_001136082 (OMIM: 608650) serine/threonine-prote (1036) 605 63.5 6.8e-09
NP_055498 (OMIM: 608650) serine/threonine-protein (1036) 605 63.5 6.8e-09
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 597 62.6 9e-09
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 597 62.6 9e-09
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 597 62.7 9.1e-09
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 597 62.7 9.1e-09
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 597 62.7 9.1e-09
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 595 62.5 9.8e-09
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 595 62.5 9.9e-09
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 595 62.5 1e-08
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 579 61.2 2.2e-08
>>NP_055079 (OMIM: 605031,616171) serine/threonine-prote (970 aa)
initn: 6431 init1: 6431 opt: 6431 Z-score: 2679.6 bits: 507.2 E(85289): 1.6e-142
Smith-Waterman score: 6431; 100.0% identity (100.0% similar) in 970 aa overlap (1-970:1-970)
10 20 30 40 50 60
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
910 920 930 940 950 960
970
pF1KE3 MFSNPTPNFH
::::::::::
NP_055 MFSNPTPNFH
970
>>XP_016863151 (OMIM: 605031,616171) PREDICTED: serine/t (971 aa)
initn: 6376 init1: 6376 opt: 6377 Z-score: 2657.3 bits: 503.1 E(85289): 2.8e-141
Smith-Waterman score: 6377; 99.4% identity (99.5% similar) in 970 aa overlap (1-970:5-971)
10 20 30 40 50
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQR
. :: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSTLDTCC---IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQR
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 VQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 YISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 SSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 RGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGEN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 EERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETV
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE3 QQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE3 VKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVA
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE3 HRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRG
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE3 FPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILME
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE3 NSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGH
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE3 RICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNR
780 790 800 810 820 830
840 850 860 870 880 890
pF1KE3 MVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNV
840 850 860 870 880 890
900 910 920 930 940 950
pF1KE3 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS
900 910 920 930 940 950
960 970
pF1KE3 SILLMFSNPTPNFH
::::::::::::::
XP_016 SILLMFSNPTPNFH
960 970
>>NP_001177730 (OMIM: 605031,616171) serine/threonine-pr (929 aa)
initn: 6169 init1: 6169 opt: 6169 Z-score: 2571.9 bits: 487.2 E(85289): 1.6e-136
Smith-Waterman score: 6169; 100.0% identity (100.0% similar) in 929 aa overlap (42-970:1-929)
20 30 40 50 60 70
pF1KE3 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS
::::::::::::::::::::::::::::::
NP_001 MIDKKAMYKAGMVQRVQNEVKIHCQLKHPS
10 20 30
80 90 100 110 120 130
pF1KE3 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 DRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE3 LLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSR
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE3 YLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFN
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE3 FFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRK
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE3 TTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE3 KPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVV
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE3 SILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNIS
580 590 600 610 620 630
680 690 700 710 720 730
pF1KE3 RYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGV
640 650 660 670 680 690
740 750 760 770 780 790
pF1KE3 KIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEER
700 710 720 730 740 750
800 810 820 830 840 850
pF1KE3 KTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPIL
760 770 780 790 800 810
860 870 880 890 900 910
pF1KE3 NPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQF
820 830 840 850 860 870
920 930 940 950 960 970
pF1KE3 NDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
880 890 900 910 920
>>NP_001177728 (OMIM: 605031,616171) serine/threonine-pr (938 aa)
initn: 5949 init1: 5949 opt: 5953 Z-score: 2482.9 bits: 470.8 E(85289): 1.5e-131
Smith-Waterman score: 6144; 96.7% identity (96.7% similar) in 970 aa overlap (1-970:1-938)
10 20 30 40 50 60
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE
::::::::::::::::::::::::::::::::::::::::::
NP_001 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKM------------------
10 20 30 40
70 80 90 100 110 120
pF1KE3 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------LYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
50 60 70 80
130 140 150 160 170 180
pF1KE3 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE3 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE3 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE3 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERY
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE3 SPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWF
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE3 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE3 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE3 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE3 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE3 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE3 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE3 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE3 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
870 880 890 900 910 920
970
pF1KE3 MFSNPTPNFH
::::::::::
NP_001 MFSNPTPNFH
930
>>XP_005262758 (OMIM: 605031,616171) PREDICTED: serine/t (936 aa)
initn: 3458 init1: 3458 opt: 3468 Z-score: 1459.8 bits: 281.5 E(85289): 1.4e-74
Smith-Waterman score: 6121; 96.4% identity (96.4% similar) in 970 aa overlap (1-970:1-936)
10 20 30 40 50 60
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEES-
370 380 390 400 410
430 440 450 460 470 480
pF1KE3 SPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWF
:::::::::::::::::::::::::::
XP_005 ---------------------------------SNHLCPGKTPFPFADPTPQTETVQQWF
420 430 440
490 500 510 520 530 540
pF1KE3 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE3 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLK
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE3 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLA
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE3 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPG
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE3 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICL
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE3 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMH
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE3 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWAT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE3 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILL
870 880 890 900 910 920
970
pF1KE3 MFSNPTPNFH
::::::::::
XP_005 MFSNPTPNFH
930
>>XP_016863152 (OMIM: 605031,616171) PREDICTED: serine/t (937 aa)
initn: 3458 init1: 3458 opt: 3468 Z-score: 1459.8 bits: 281.5 E(85289): 1.4e-74
Smith-Waterman score: 6067; 95.8% identity (95.9% similar) in 970 aa overlap (1-970:5-937)
10 20 30 40 50
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQR
. :: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSTLDTCC---IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQR
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 VQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 YISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 SSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 RGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGEN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 EERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETV
:: :::::::::::::::::::::::
XP_016 EES----------------------------------SNHLCPGKTPFPFADPTPQTETV
420 430 440
480 490 500 510 520 530
pF1KE3 QQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHS
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE3 VKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVA
510 520 530 540 550 560
600 610 620 630 640 650
pF1KE3 HRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRG
570 580 590 600 610 620
660 670 680 690 700 710
pF1KE3 FPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILME
630 640 650 660 670 680
720 730 740 750 760 770
pF1KE3 NSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGH
690 700 710 720 730 740
780 790 800 810 820 830
pF1KE3 RICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNR
750 760 770 780 790 800
840 850 860 870 880 890
pF1KE3 MVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNV
810 820 830 840 850 860
900 910 920 930 940 950
pF1KE3 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS
870 880 890 900 910 920
960 970
pF1KE3 SILLMFSNPTPNFH
::::::::::::::
XP_016 SILLMFSNPTPNFH
930
>>NP_004064 (OMIM: 602913) serine/threonine-protein kina (646 aa)
initn: 801 init1: 561 opt: 756 Z-score: 344.7 bits: 74.6 E(85289): 1.8e-12
Smith-Waterman score: 756; 37.4% identity (71.7% similar) in 297 aa overlap (15-311:65-356)
10 20 30 40
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
: :::::.:: :.: . .:: :.:.:
NP_004 GPELEMLAGLPTSDPGRLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIP
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE3 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
.. . : . ... ::...: .:.: :... ..:::.. .:. ::.: . . : :
NP_004 QSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKAR
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE3 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
. . : :.:....::..:. :::..::::::: :.:...:.::..:..:::::..:. :
NP_004 -HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPP
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE3 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
.... :.::::::..::. :..:: :.:::::::..:::: : :::.: .:.: .
NP_004 EQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIK
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE3 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
. : .:. ::. :..:. .:: .: :: :....: : :.... . ... :
NP_004 QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVPD
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE3 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
. . .. :. .. ::: ...
NP_004 LTPPNPARSLFAK----VTKSLFGRKKKSKNHAQERDEVSGLVSGLMRTSVGHQDARPEA
340 350 360 370 380
>>NP_001239155 (OMIM: 607023) serine/threonine-protein k (671 aa)
initn: 751 init1: 547 opt: 731 Z-score: 334.2 bits: 72.7 E(85289): 7.1e-12
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (15-264:71-319)
10 20 30 40
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
:..::::.:: :. .. .. : :.:
NP_001 ESQPPQSQAQVPPAISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE3 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
NP_001 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE3 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
NP_001 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
170 180 190 200 210
170 180 190 200 210 220
pF1KE3 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
NP_001 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE3 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
: : ::: : :: :: ..: .:: :: ::.... : :
NP_001 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE3 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
NP_001 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
340 350 360 370 380 390
>>NP_006613 (OMIM: 607023) serine/threonine-protein kina (685 aa)
initn: 751 init1: 547 opt: 731 Z-score: 334.2 bits: 72.8 E(85289): 7.1e-12
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (15-264:85-333)
10 20 30 40
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
:..::::.:: :. .. .. : :.:
NP_006 APHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE3 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
NP_006 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE3 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
NP_006 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE3 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
NP_006 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE3 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
: : ::: : :: :: ..: .:: :: ::.... : :
NP_006 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
300 310 320 330 340 350
290 300 310 320 330 340
pF1KE3 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
NP_006 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
360 370 380 390 400 410
>>NP_005021 (OMIM: 602098) serine/threonine-protein kina (603 aa)
initn: 683 init1: 529 opt: 687 Z-score: 316.5 bits: 69.3 E(85289): 6.8e-11
Smith-Waterman score: 687; 37.7% identity (76.2% similar) in 252 aa overlap (15-266:56-306)
10 20 30 40
pF1KE3 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
: .::::.:: .. . : : :..
NP_005 AAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVP
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE3 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
:. . : . .... :..:: .: : .. ....:::...:..:::.:. . . :..:
NP_005 KSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLE-LHKR
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE3 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
: ..: :::....::. : ::: . ..:::: :.::.:......::.::::::....
NP_005 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE3 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
:.. :::::::::.::. ....:..: ::::.::..::::.:.:::.:. .:.: ..
NP_005 GERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIK
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE3 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
.: .:. .. : .::...:. .:. : ... .:. :..
NP_005 KNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPR
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE3 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
NP_005 FSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSV
330 340 350 360 370 380
970 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:19:15 2016 done: Sun Nov 6 06:19:17 2016
Total Scan time: 13.860 Total Display time: 0.280
Function used was FASTA [36.3.4 Apr, 2011]