Result of FASTA (omim) for
pFN21AE3658
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3658, 164 aa
1>>>pF1KE3658 164 - 164 aa - 164 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6880+/-0.000288; mu= 15.1477+/- 0.018
mean_var=55.6671+/-11.429, 0's: 0 Z-trim(117.2): 25 B-trim: 0 in 0/55
Lambda= 0.171900
statistics sampled from 29056 (29081) to 29056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.341), width: 16
Scan time: 4.600
The best scores are: opt bits E(85289)
NP_004576 (OMIM: 605092) retinoic acid receptor re ( 164) 1095 279.0 2.4e-75
NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 ( 162) 543 142.1 3.9e-34
XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like s ( 162) 543 142.1 3.9e-34
NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [H ( 162) 543 142.1 3.9e-34
XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like s ( 177) 532 139.4 2.7e-33
NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [H ( 162) 527 138.1 6e-33
XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like s ( 195) 520 136.4 2.3e-32
XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 496 130.4 1.2e-30
XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 496 130.4 1.2e-30
XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 268) 497 130.8 1.6e-30
NP_001140201 (OMIM: 611474) Ca(2+)-independent N-a ( 269) 497 130.8 1.6e-30
NP_473449 (OMIM: 611474) Ca(2+)-independent N-acyl ( 279) 497 130.8 1.6e-30
XP_016862412 (OMIM: 606487) PREDICTED: phospholipi ( 168) 450 119.0 3.5e-27
NP_065119 (OMIM: 606487) phospholipid-metabolizing ( 273) 450 119.2 5.2e-27
XP_011511337 (OMIM: 606487) PREDICTED: phospholipi ( 339) 437 116.0 5.7e-26
XP_011511336 (OMIM: 606487) PREDICTED: phospholipi ( 342) 437 116.0 5.8e-26
NP_001140200 (OMIM: 611474) Ca(2+)-independent N-a ( 253) 405 108.0 1.1e-23
XP_011543054 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 167) 310 84.3 9.8e-17
>>NP_004576 (OMIM: 605092) retinoic acid receptor respon (164 aa)
initn: 1095 init1: 1095 opt: 1095 Z-score: 1473.7 bits: 279.0 E(85289): 2.4e-75
Smith-Waterman score: 1095; 100.0% identity (100.0% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
70 80 90 100 110 120
130 140 150 160
pF1KE3 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
::::::::::::::::::::::::::::::::::::::::::::
NP_004 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
130 140 150 160
>>NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 [Ho (162 aa)
initn: 514 init1: 514 opt: 543 Z-score: 733.9 bits: 142.1 E(85289): 3.9e-34
Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-161:1-162)
10 20 30 40 50 60
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
: .: :::::::::::: :.:::.:.:::::.::::::: :::..::.:.:...: :
NP_001 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
:.: : ::.:. :.:::. : .:.: : ::. :.:.:::.. :...:.::::::..:
NP_001 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE3 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
::: .: ::. . . ..:: .:. . . : :. . ::.
NP_001 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like suppr (162 aa)
initn: 514 init1: 514 opt: 543 Z-score: 733.9 bits: 142.1 E(85289): 3.9e-34
Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-161:1-162)
10 20 30 40 50 60
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
: .: :::::::::::: :.:::.:.:::::.::::::: :::..::.:.:...: :
XP_006 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
:.: : ::.:. :.:::. : .:.: : ::. :.:.:::.. :...:.::::::..:
XP_006 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE3 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
::: .: ::. . . ..:: .:. . . : :. . ::.
XP_006 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [Homo (162 aa)
initn: 514 init1: 514 opt: 543 Z-score: 733.9 bits: 142.1 E(85289): 3.9e-34
Smith-Waterman score: 543; 51.2% identity (77.8% similar) in 162 aa overlap (1-161:1-162)
10 20 30 40 50 60
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
: .: :::::::::::: :.:::.:.:::::.::::::: :::..::.:.:...: :
NP_009 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
:.: : ::.:. :.:::. : .:.: : ::. :.:.:::.. :...:.::::::..:
NP_009 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE3 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
::: .: ::. . . ..:: .:. . . : :. . ::.
NP_009 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like suppr (177 aa)
initn: 514 init1: 514 opt: 532 Z-score: 718.6 bits: 139.4 E(85289): 2.7e-33
Smith-Waterman score: 532; 51.9% identity (78.8% similar) in 156 aa overlap (7-161:22-177)
10 20 30 40
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGA
:::::::::::: :.:::.:.:::::.::::::: ::
XP_011 MKTQRSSWCQLLLHRIGQRIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 GSSSVFSVLSNSAEVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMK
:..::.:.:...: ::.: : ::.:. :.:::. : .:.: : ::. :.:.:::..
XP_011 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 YSIVSRNCEHFVTQLRYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKKATA
:...:.::::::..:::: .: ::. . . ..:: .:. . . : :. . ::.
XP_011 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160 170
>>NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [Homo (162 aa)
initn: 540 init1: 526 opt: 527 Z-score: 712.5 bits: 138.1 E(85289): 6e-33
Smith-Waterman score: 527; 55.7% identity (77.9% similar) in 149 aa overlap (1-149:1-147)
10 20 30 40 50 60
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
:: . .:. :::::: :.:: :::.:.:::::.:::: :: :::..::.:.:.:.: :
NP_060 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
:.: : :.:: :::::. : .: : : . :.. :.:.:::.. ::..: ::::::..:
NP_060 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
70 80 90 100 110 120
130 140 150 160
pF1KE3 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
::: :: :: : . ::::. :.:..:
NP_060 RYGVSRSDQVTGAVTTVGVAA--GLLAAASLVGILLARSKRERQ
130 140 150 160
>>XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like suppr (195 aa)
initn: 524 init1: 510 opt: 520 Z-score: 701.9 bits: 136.4 E(85289): 2.3e-32
Smith-Waterman score: 520; 57.0% identity (78.9% similar) in 142 aa overlap (8-149:41-180)
10 20 30
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLA
:. :::::: :.:: :::.:.:::::.:::
XP_011 FQFWLQSICIPTLKLFVCLFVYSLKRARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 PPSEYPGAGSSSVFSVLSNSAEVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAK
: :: :::..::.:.:.:.: ::.: : :.:: :::::. : .: : : . :.. :.
XP_011 PASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 EMVGQKMKYSIVSRNCEHFVTQLRYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRR
:.:::.. ::..: ::::::..:::: :: :: : . ::::. :.:..:
XP_011 ELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAA--GLLAAASLVGILLA
140 150 160 170 180
160
pF1KE3 YQKKATA
XP_011 RSKRERQ
190
>>XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-independ (159 aa)
initn: 478 init1: 284 opt: 496 Z-score: 671.0 bits: 130.4 E(85289): 1.2e-30
Smith-Waterman score: 496; 54.9% identity (75.4% similar) in 142 aa overlap (8-149:10-147)
10 20 30 40 50
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSA
:.:::::::::.::::::.:. : :.::::::: .: :. :..:: :
XP_011 MSRSVGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVT
:: :::::. :: ..:::.:: : : ::. ::. .:.::.. ..::.. ::::::.
XP_011 VVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVN
60 70 80 90 100 110
120 130 140 150 160
pF1KE3 QLRYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
:::: : .:::.: .: : : : : .. :
XP_011 GLRYGVPRSQQVEHALME-G-AKAAGAVISAVVDSIKPKPITA
120 130 140 150
>>XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-independ (159 aa)
initn: 478 init1: 284 opt: 496 Z-score: 671.0 bits: 130.4 E(85289): 1.2e-30
Smith-Waterman score: 496; 54.9% identity (75.4% similar) in 142 aa overlap (8-149:10-147)
10 20 30 40 50
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSA
:.:::::::::.::::::.:. : :.::::::: .: :. :..:: :
XP_016 MSRSVGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVT
:: :::::. :: ..:::.:: : : ::. ::. .:.::.. ..::.. ::::::.
XP_016 VVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVN
60 70 80 90 100 110
120 130 140 150 160
pF1KE3 QLRYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
:::: : .:::.: .: : : : : .. :
XP_016 GLRYGVPRSQQVEHALME-G-AKAAGAVISAVVDSIKPKPITA
120 130 140 150
>>XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-independ (268 aa)
initn: 479 init1: 284 opt: 497 Z-score: 669.1 bits: 130.8 E(85289): 1.6e-30
Smith-Waterman score: 497; 53.4% identity (74.3% similar) in 148 aa overlap (2-149:113-256)
10 20 30
pF1KE3 MASPHQEPKPGDLIEIFRLGYEHWALYIGDG
: . .:.:::::::::.::::::.:. :
XP_011 VVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDD
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE3 YVIHLAPPSEYPGAGSSSVFSVLSNSAEVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEV
:.::::::: .:: . :..:: : :: :::::. :: ..:::.:: : : ::.
XP_011 CVVHLAPPSEEFEVGS--ITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDK
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE3 IISSAKEMVGQKMKYSIVSRNCEHFVTQLRYGKSRCKQVEKAKVEVGVATALGILVVAGC
::. .:.::.. ..::.. ::::::. :::: : .:::.: .: : : : : .. :
XP_011 IIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALME-G-AKAAGAVISAVV
210 220 230 240 250
160
pF1KE3 SFAIRRYQKKATA
XP_011 DSIKPKPITA
260
164 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:03:02 2016 done: Mon Nov 7 02:03:02 2016
Total Scan time: 4.600 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]