Result of FASTA (ccds) for
pFN21AE3648
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3648, 234 aa
1>>>pF1KE3648 234 - 234 aa - 234 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2758+/-0.000868; mu= 14.1821+/- 0.053
mean_var=71.6049+/-14.102, 0's: 0 Z-trim(107.3): 175 B-trim: 304 in 1/49
Lambda= 0.151566
statistics sampled from 9300 (9494) to 9300 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.292), width: 16
Scan time: 2.210
The best scores are: opt bits E(32554)
CCDS9512.1 RAB20 gene_id:55647|Hs108|chr13 ( 234) 1562 350.5 5.5e-97
CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 303 75.2 3.9e-14
CCDS2520.1 RAB17 gene_id:64284|Hs108|chr2 ( 212) 279 69.9 1.4e-12
CCDS45826.1 RAB31 gene_id:11031|Hs108|chr18 ( 195) 274 68.8 2.9e-12
CCDS8264.1 RAB30 gene_id:27314|Hs108|chr11 ( 203) 272 68.4 4e-12
CCDS2633.1 RAB5A gene_id:5868|Hs108|chr3 ( 215) 270 68.0 5.7e-12
CCDS33497.1 RAB22A gene_id:57403|Hs108|chr20 ( 194) 267 67.3 8.2e-12
CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 ( 207) 267 67.3 8.7e-12
CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 ( 207) 266 67.1 1e-11
CCDS11419.1 RAB5C gene_id:5878|Hs108|chr17 ( 216) 266 67.1 1e-11
CCDS58551.1 RAB5C gene_id:5878|Hs108|chr17 ( 249) 266 67.1 1.2e-11
CCDS3052.1 RAB7A gene_id:7879|Hs108|chr3 ( 207) 257 65.1 3.9e-11
CCDS8900.1 RAB5B gene_id:5869|Hs108|chr12 ( 215) 257 65.1 4.1e-11
CCDS1720.1 RAB10 gene_id:10890|Hs108|chr2 ( 200) 256 64.9 4.5e-11
CCDS42410.1 RAB12 gene_id:201475|Hs108|chr18 ( 244) 257 65.2 4.5e-11
CCDS14515.1 RAB9B gene_id:51209|Hs108|chrX ( 201) 255 64.7 5.2e-11
>>CCDS9512.1 RAB20 gene_id:55647|Hs108|chr13 (234 aa)
initn: 1562 init1: 1562 opt: 1562 Z-score: 1854.7 bits: 350.5 E(32554): 5.5e-97
Smith-Waterman score: 1562; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)
10 20 30 40 50 60
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLKQWRSYNISIWDTAGRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLKQWRSYNISIWDTAGRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 QFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQMCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 GALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQMCF
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 ETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPPKRTRSGCCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS95 ETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPPKRTRSGCCA
190 200 210 220 230
>>CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 (225 aa)
initn: 312 init1: 196 opt: 303 Z-score: 367.2 bits: 75.2 E(32554): 3.9e-14
Smith-Waterman score: 303; 34.1% identity (65.3% similar) in 170 aa overlap (7-170:21-189)
10 20 30 40
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDT-VSTVGGAFYLKQ
:.::::. ::::::. :: : .: : ..:. ..: :.
CCDS90 MAAAGGGGGGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 W----RSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDT
. :..::::::.:.::.:: .: : . . ::.::.. ..:. .... :
CCDS90 LNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 ASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGD-RVSPRAPKQVQLEDAVALYKK
... . :::::.:: .: .. :: : . .. : ..: . : .. : . : :.
CCDS90 LGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIE-ELFLDLCKR
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 ILKYKMLDEQDVPAAEQMCFETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDIS
... ..::.
CCDS90 MIETAQVDERAKGNGSSQPGTARRGVQIIDDEPQAQTSGGGCCSSG
180 190 200 210 220
>>CCDS2520.1 RAB17 gene_id:64284|Hs108|chr2 (212 aa)
initn: 321 init1: 136 opt: 279 Z-score: 339.2 bits: 69.9 E(32554): 1.4e-12
Smith-Waterman score: 279; 38.0% identity (68.2% similar) in 129 aa overlap (7-130:21-149)
10 20 30 40
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLK--
:.::::. .:::.:: ::.. : . . ::: ::. :
CCDS25 MAQAHRTPQPRAAPSQPRVFKLVLLGSGSVGKSSLALRYVKNDFKSILPTVGCAFFTKVV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 --QWRSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTA
: .. ::::::.:..:.. .: ::: : .:.::.....:... .. . : .
CCDS25 DVGATSLKLEIWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEEL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 SK-DCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKI
. : .::::.::..: .. :: .:
CCDS25 HPGEVLVMLVGNKTDLSQEREVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQEL
130 140 150 160 170 180
>>CCDS45826.1 RAB31 gene_id:11031|Hs108|chr18 (195 aa)
initn: 329 init1: 191 opt: 274 Z-score: 333.8 bits: 68.8 E(32554): 2.9e-12
Smith-Waterman score: 274; 34.6% identity (69.1% similar) in 136 aa overlap (7-137:8-143)
10 20 30 40 50
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVS-TVGGAFYLKQWRSYN----ISIW
:. :::: .:::.:.. :... .: ..: :.:..:. : : . ::
CCDS45 MMAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 DTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNK
::::.:.::.:. :: ::.:: ...::.....:. :. : . . .. ..::.:::
CCDS45 DTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPA
::.. . .. .: . .. :
CCDS45 CDLSDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPLDPHENGNNGT
130 140 150 160 170 180
>>CCDS8264.1 RAB30 gene_id:27314|Hs108|chr11 (203 aa)
initn: 302 init1: 196 opt: 272 Z-score: 331.2 bits: 68.4 E(32554): 4e-12
Smith-Waterman score: 272; 37.0% identity (70.4% similar) in 135 aa overlap (7-136:11-145)
10 20 30 40 50
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTV-STVGGAFYLK----QWRSYNI
::::.:. .:::: :..:. . :: .:.: :..: . .. ..
CCDS82 MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 SIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIV
.::::::.:.:... . : :.: :.:::::.. ..:. : . . . . ::. . ..:
CCDS82 QIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 GNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQD
:::.::.:. .. :. :: : .:
CCDS82 GNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLV
130 140 150 160 170 180
>>CCDS2633.1 RAB5A gene_id:5868|Hs108|chr3 (215 aa)
initn: 351 init1: 195 opt: 270 Z-score: 328.4 bits: 68.0 E(32554): 5.7e-12
Smith-Waterman score: 270; 37.5% identity (70.3% similar) in 128 aa overlap (7-129:22-149)
10 20 30 40
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPD-TVSTVGGAFYLK
:.::::. :::.::. :... .: . ::.:.:: .
CCDS26 MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 QW----RSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTD
. .. ::::::.:..:.:. :: ::: : :..::.....:... .. :
CCDS26 TVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 TASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKK
:: . ..:. :::.::... :. :: .
CCDS26 QASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKK
130 140 150 160 170 180
>>CCDS33497.1 RAB22A gene_id:57403|Hs108|chr20 (194 aa)
initn: 287 init1: 174 opt: 267 Z-score: 325.5 bits: 67.3 E(32554): 8.2e-12
Smith-Waterman score: 267; 38.1% identity (72.9% similar) in 118 aa overlap (7-119:7-124)
10 20 30 40 50
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRF-PDTVSTVGGAFYLK--QWRS--YNISIWD
:. :::: .:::.:.. :..: : :. :.:..:. : :... ... :::
CCDS33 MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 TAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKV
:::.:.:..:. :: ::.:: :..::....... :.. : . . . . ::.:::
CCDS33 TAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 DLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAA
:: .
CCDS33 DLIDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANLPSGGKGF
130 140 150 160 170 180
>>CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 (207 aa)
initn: 252 init1: 170 opt: 267 Z-score: 325.1 bits: 67.3 E(32554): 8.7e-12
Smith-Waterman score: 267; 30.7% identity (66.3% similar) in 166 aa overlap (7-166:10-173)
10 20 30 40 50
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDT-VSTVGGAFYLK----QWRSYNIS
:..:.:: .:::: .: :. : : .: .::.: : .. . . ...
CCDS12 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVG
::::::.:.:. . . : ::: .:.:.::.....:. .... . .. . :: : :.:
CCDS12 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPK-QVQLEDAVALYKKILKYKMLDEQD
:: :.... .. .. :. . .: : . . : ....:.: . .: ::
CCDS12 NKCDVNDKRQVSKERGEKLA--LDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLE
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 VPAAEQMCFETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPPKRTRSG
CCDS12 GNSPQGSNQGVKITPDQQKRSSFFRCVLL
180 190 200
>>CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 (207 aa)
initn: 263 init1: 175 opt: 266 Z-score: 323.9 bits: 67.1 E(32554): 1e-11
Smith-Waterman score: 266; 30.4% identity (66.5% similar) in 194 aa overlap (7-188:10-201)
10 20 30 40 50
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDT-VSTVGGAFYLK----QWRSYNIS
:..:.:: .:::: :: :. : : : .::.: : .. . .. ...
CCDS10 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVG
::::::.:.:. . . : ::: .:.:.::.....:. .... . .. . ::.: :.:
CCDS10 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILG
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 NKVDLTEEGALAGQEKEECSPNMDAGDR-VSPRAPKQVQLEDAV-ALYKKI---LKYKML
:: :.... .. .. :. . .: : . . : .....:.: .: . : :. ::
CCDS10 NKCDMNDKRQVSKERGEKLA--IDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMN
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 DEQDVPAAE--QMCFETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPP
: ... :. .. . : ::..
CCDS10 DSNSAGAGGPVKITENRSKKTSFFRCSLL
180 190 200
>>CCDS11419.1 RAB5C gene_id:5878|Hs108|chr17 (216 aa)
initn: 346 init1: 191 opt: 266 Z-score: 323.7 bits: 67.1 E(32554): 1e-11
Smith-Waterman score: 266; 36.7% identity (69.5% similar) in 128 aa overlap (7-129:23-150)
10 20 30 40
pF1KE3 MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPD-TVSTVGGAFYL
:.::::. :::.::. :... .: . ::.:.::
CCDS11 MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLT
10 20 30 40 50 60
50 60 70 80 90
pF1KE3 KQW----RSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLT
. . .. ::::::.:..:.:. :: ::: : :..::... ..... .. :
CCDS11 QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 DTASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYK
:: . ..:..:::.::. . :. :: .
CCDS11 RQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK
130 140 150 160 170 180
234 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:31:10 2016 done: Mon Nov 7 00:31:11 2016
Total Scan time: 2.210 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]