Result of FASTA (omim) for
pFN21AE3643
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3643, 197 aa
1>>>pF1KE3643 197 - 197 aa - 197 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1954+/-0.000287; mu= 14.5819+/- 0.018
mean_var=73.3129+/-14.887, 0's: 0 Z-trim(119.3): 128 B-trim: 0 in 0/50
Lambda= 0.149790
statistics sampled from 33065 (33200) to 33065 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.389), width: 16
Scan time: 6.090
The best scores are: opt bits E(85289)
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 1348 299.7 2.1e-81
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 1086 243.0 2e-64
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 464 108.5 5.4e-24
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 433 101.8 5.5e-22
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 432 101.6 6.3e-22
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 428 100.8 1.2e-21
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 426 100.3 1.6e-21
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 422 99.5 2.9e-21
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 420 99.1 4.3e-21
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 400 94.7 8.2e-20
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 400 94.8 9.5e-20
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 400 94.8 9.8e-20
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 400 94.8 9.8e-20
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 398 94.4 1.3e-19
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 398 94.4 1.3e-19
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 398 94.4 1.3e-19
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 398 94.4 1.3e-19
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 398 94.4 1.3e-19
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 388 92.0 3.9e-19
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 384 91.2 6.7e-19
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 384 91.2 7.1e-19
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 384 91.2 7.1e-19
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 381 90.7 1.7e-18
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 376 89.4 2.2e-18
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 363 86.7 2e-17
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 362 86.5 2.3e-17
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 351 84.2 1.4e-16
NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 346 83.0 2.2e-16
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 347 83.3 2.2e-16
NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 346 83.1 3.3e-16
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 329 79.4 3.4e-15
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 323 78.1 9.1e-15
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 319 77.1 1.2e-14
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 321 77.7 1.3e-14
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 315 76.3 2.7e-14
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 314 76.2 3.3e-14
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 314 76.2 4.2e-14
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 301 73.3 2e-13
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 298 72.7 3.5e-13
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 298 72.7 3.5e-13
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 298 72.7 3.5e-13
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 298 72.7 3.5e-13
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 298 72.7 3.5e-13
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 292 71.4 9.6e-13
>>NP_054895 (OMIM: 610538,616435) ubiquitin-conjugating (197 aa)
initn: 1348 init1: 1348 opt: 1348 Z-score: 1582.6 bits: 299.7 E(85289): 2.1e-81
Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
130 140 150 160 170 180
190
pF1KE3 RKASQLVGIEKKFHPDV
:::::::::::::::::
NP_054 RKASQLVGIEKKFHPDV
190
>>NP_001297255 (OMIM: 610538,616435) ubiquitin-conjugati (167 aa)
initn: 1086 init1: 1086 opt: 1086 Z-score: 1277.6 bits: 243.0 E(85289): 2e-64
Smith-Waterman score: 1086; 99.4% identity (100.0% similar) in 161 aa overlap (37-197:7-167)
10 20 30 40 50 60
pF1KE3 LKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPERYPFEPP
.:::::::::::::::::::::::::::::
NP_001 MTCELVEILGGANTPYEKGVFKLEVIIPERYPFEPP
10 20 30
70 80 90 100 110 120
pF1KE3 QIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 DISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQKRKASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQKRKASQL
100 110 120 130 140 150
190
pF1KE3 VGIEKKFHPDV
:::::::::::
NP_001 VGIEKKFHPDV
160
>>NP_003339 (OMIM: 603679) ubiquitin-conjugating enzyme (152 aa)
initn: 451 init1: 294 opt: 464 Z-score: 551.8 bits: 108.5 E(85289): 5.4e-24
Smith-Waterman score: 464; 45.9% identity (71.9% similar) in 146 aa overlap (6-151:7-148)
10 20 30 40 50
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPE
:. .: . : .:: ::: :... ... : : ..:.: :.::::...::
NP_003 MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 RYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPN
.::. :..::.: :::::.:. ::::::.:: : :.:.: ::: ::: :.: ::
NP_003 EYPMAAPKVRFMTKIYHPNVDKLGRICLDILK----DKWSPALQIRTVLLSIQALLSAPN
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 PDDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQ
::::: :.. ..: :. ...:: ::. .:
NP_003 PDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
120 130 140 150
180 190
pF1KE3 KRKASQLVGIEKKFHPDV
>>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa)
initn: 391 init1: 259 opt: 433 Z-score: 515.7 bits: 101.8 E(85289): 5.5e-22
Smith-Waterman score: 433; 43.8% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: :: .:: . :.: .: :.: ..::. ::: : . .:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_871 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . ::.::::.:
NP_871 DDPLVPEIARIYKTDRDKYNRLAREWTEKYAML
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 390 init1: 261 opt: 432 Z-score: 514.6 bits: 101.6 E(85289): 6.3e-22
Smith-Waterman score: 432; 43.2% identity (68.5% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...::. :: .:: . :.: .: :.: ..::. ::: : . .:
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_003 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . ::.::.:.:
NP_003 DDPLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 385 init1: 242 opt: 428 Z-score: 509.9 bits: 100.8 E(85289): 1.2e-21
Smith-Waterman score: 428; 43.2% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: : .:: . :.. .: :.: .. :. ::: : : .:
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.: : : ::::::.: : ::::.:. . : :.:... :: :: :. .:::
NP_003 YPFKPPKIAFTTKIYHPNINSNGSICLDILR----SQWSPALTVSKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. ::.. .: .: . ..::.::.:.:
NP_003 DDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 384 init1: 259 opt: 426 Z-score: 507.6 bits: 100.3 E(85289): 1.6e-21
Smith-Waterman score: 426; 42.5% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: :: .:: . :.: .: :.: ..::. ::: : . .:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_871 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . .:.::.:.:
NP_871 DDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 384 init1: 259 opt: 426 Z-score: 507.6 bits: 100.3 E(85289): 1.6e-21
Smith-Waterman score: 426; 42.5% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: :: .:: . :.: .: :.: ..::. ::: : . .:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_871 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . .:.::.:.:
NP_871 DDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_871615 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 384 init1: 259 opt: 426 Z-score: 507.6 bits: 100.3 E(85289): 1.6e-21
Smith-Waterman score: 426; 42.5% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: :: .:: . :.: .: :.: ..::. ::: : . .:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_871 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . .:.::.:.:
NP_871 DDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 384 init1: 259 opt: 426 Z-score: 507.6 bits: 100.3 E(85289): 1.6e-21
Smith-Waterman score: 426; 42.5% identity (67.8% similar) in 146 aa overlap (6-151:5-146)
10 20 30 40 50 60
pF1KE3 MQRASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKLEVIIPER
:...:: :: .:: . :.: .: :.: ..::. ::: : . .:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLNIATVLTSIQLLMSEPNP
:::.::.. : : ::::::.: : ::::.:. . : :.:.:. :: :: :. .:::
NP_871 YPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSICSLLCDPNP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 DDPLMADISSEFKYNKPAFLKNARQWTEKHARQKQKADEEEMLDNLPEAGDSRVHNSTQK
::::. .:. .: .. . . .:.::.:.:
NP_871 DDPLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
190
pF1KE3 RKASQLVGIEKKFHPDV
197 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:31:03 2016 done: Mon Nov 7 02:31:04 2016
Total Scan time: 6.090 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]