Result of FASTA (ccds) for
pFN21AE3638
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3638, 426 aa
1>>>pF1KE3638 426 - 426 aa - 426 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2655+/-0.00101; mu= 12.7102+/- 0.060
mean_var=81.9369+/-16.187, 0's: 0 Z-trim(105.2): 24 B-trim: 2 in 1/50
Lambda= 0.141688
statistics sampled from 8272 (8283) to 8272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.254), width: 16
Scan time: 2.910
The best scores are: opt bits E(32554)
CCDS2777.1 IP6K2 gene_id:51447|Hs108|chr3 ( 426) 2858 594.1 8.3e-170
CCDS33760.1 IP6K1 gene_id:9807|Hs108|chr3 ( 441) 1156 246.2 4.6e-65
CCDS34435.1 IP6K3 gene_id:117283|Hs108|chr6 ( 410) 1025 219.4 5e-57
CCDS43092.1 IP6K1 gene_id:9807|Hs108|chr3 ( 276) 809 175.2 6.8e-44
CCDS54579.1 IP6K2 gene_id:51447|Hs108|chr3 ( 87) 481 108.0 3.7e-24
CCDS33752.1 IP6K2 gene_id:51447|Hs108|chr3 ( 97) 476 107.0 8.4e-24
CCDS54580.1 IP6K2 gene_id:51447|Hs108|chr3 ( 185) 476 107.1 1.5e-23
CCDS54581.1 IP6K2 gene_id:51447|Hs108|chr3 ( 188) 476 107.1 1.5e-23
CCDS7250.1 IPMK gene_id:253430|Hs108|chr10 ( 416) 303 71.9 1.3e-12
>>CCDS2777.1 IP6K2 gene_id:51447|Hs108|chr3 (426 aa)
initn: 2858 init1: 2858 opt: 2858 Z-score: 3162.1 bits: 594.1 E(32554): 8.3e-170
Smith-Waterman score: 2858; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
370 380 390 400 410 420
pF1KE3 SEESGE
::::::
CCDS27 SEESGE
>>CCDS33760.1 IP6K1 gene_id:9807|Hs108|chr3 (441 aa)
initn: 1316 init1: 809 opt: 1156 Z-score: 1281.6 bits: 246.2 E(32554): 4.6e-65
Smith-Waterman score: 1310; 50.0% identity (74.3% similar) in 424 aa overlap (15-424:22-440)
10 20 30 40 50
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYE
.:::::::.::::::: ..:... :.::::. ::..:::
CCDS33 MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 TLPAEMRKFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCE-PKSKLLR
.:: ::..:::.::::::: :: : : . :.::: . :. :... : :. : :
CCDS33 SLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYV-ESETVEQDDTTEREQPRRKHSR
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 WTTNKKHHVLE-TEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISS
. ... . :. . .. .. .. :: :.: . ..::: . .. ....::
CCDS33 RSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELH----SHSEVPFQMLDGNSGLSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 QLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDD
. .::::..::.:::.::. ..: :. :::.::::.. ... ::::::::::::::::
CCDS33 EKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 ASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQ
:: :::: :.:::.:::::..::::::::::: .:. . :::.:: ::..::..::.:
CCDS33 ASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 FFHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE-RPEVVLDSDAE
..::: :::.:. :.:.:: :::::::: ::::::::::::::::: : : :: .:
CCDS33 YLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSE
300 310 320 330 340 350
360 370 380 390
pF1KE3 -DLEDLS------EESADESAGAYAYKP-IGASS---VDVRMIDFAHTTCRLYGEDTVVH
:. :. : :.. .: : :: ::::::::::.: . . .: .::
CCDS33 MRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVH
360 370 380 390 400 410
400 410 420
pF1KE3 EGQDAGYIFGLQSLIDIVTEISEESGE
.: : ::.:::..::.:. .. .:.
CCDS33 DGPDRGYVFGLENLISIMEQMRDENQ
420 430 440
>>CCDS34435.1 IP6K3 gene_id:117283|Hs108|chr6 (410 aa)
initn: 1195 init1: 737 opt: 1025 Z-score: 1137.3 bits: 219.4 E(32554): 5e-57
Smith-Waterman score: 1175; 45.7% identity (70.5% similar) in 407 aa overlap (16-422:15-408)
10 20 30 40 50 60
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
:: ::::.:::::: :....: :.::::: ::..:::.:: :.
CCDS34 MVVQNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRFYESLPLAMK
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
.:::::::.:.:.. .: .: :.: :.: .. . .: . :. ::...
CCDS34 RFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTLQQTTGSNGS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
. :. . . :: :. : . . . :: .. . . : .:::.
CCDS34 DCTLAQWPHAQLARSPKESPAKALLRSEP----HLNTPAFSLVEDTNGNQVERKSFNPWG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
..::: .: :. . . ....:.::::..:.: ::::::::::::::::::::: : .
CCDS34 LQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARH
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
.::: ::::: .:::.:::::::. . .. .::.::::::.::..::.::.::: .::
CCDS34 MRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
:::: :.:..: : .:.. : :::::::::::::::.: :: . : .
CCDS34 RELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSP---------HPH
300 310 320 330 340
370 380 390 400 410 420
pF1KE3 DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
. .:.. .: : ..::.::::::::: . : .. ....: : ::::::..:: :. .:
CCDS34 EAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEHTTYDGPDPGYIFGLENLIRILQDI
350 360 370 380 390 400
pF1KE3 SEESGE
.:
CCDS34 QEGE
410
>>CCDS43092.1 IP6K1 gene_id:9807|Hs108|chr3 (276 aa)
initn: 964 init1: 795 opt: 809 Z-score: 901.5 bits: 175.2 E(32554): 6.8e-44
Smith-Waterman score: 963; 56.2% identity (77.2% similar) in 272 aa overlap (167-424:4-275)
140 150 160 170 180 190
pF1KE3 KEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGN--ISSQLKHYNPWSMKCHQQQLQRMKEN
:: .::. .::::..::.:::.::. .
CCDS43 MLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSE
10 20 30
200 210 220 230 240 250
pF1KE3 AKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGV
.: :. :::.::::.. ... :::::::::::::::::: :::: :.:::.:::::..::
CCDS43 SKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGV
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE3 RVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTEL
::::::::: .:. . :::.:: ::..::..::.:..::: :::.:. :.:.:: :
CCDS43 RVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGL
100 110 120 130 140 150
320 330 340 350 360
pF1KE3 KAVLERQESYRFYSSSLLVIYDGKE-RPEVVLDSDAE-DLEDLS------EESADESAGA
::::::: ::::::::::::::::: : : :: .: :. :. : :..
CCDS43 KAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVASSCGPSTSP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE3 YAYKP-IGASS---VDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEISE
.: : :: ::::::::::.: . . .: .::.: : ::.:::..::.:. .. .
CCDS43 SNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRD
220 230 240 250 260 270
pF1KE3 ESGE
:.
CCDS43 ENQ
>>CCDS54579.1 IP6K2 gene_id:51447|Hs108|chr3 (87 aa)
initn: 499 init1: 481 opt: 481 Z-score: 547.1 bits: 108.0 E(32554): 3.7e-24
Smith-Waterman score: 481; 97.2% identity (98.6% similar) in 71 aa overlap (1-71:1-71)
10 20 30 40 50 60
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
:::::::: .:
CCDS54 KFTPQYKGDISSHQHGGVFVGEWGSLL
70 80
>>CCDS33752.1 IP6K2 gene_id:51447|Hs108|chr3 (97 aa)
initn: 506 init1: 476 opt: 476 Z-score: 540.8 bits: 107.0 E(32554): 8.4e-24
Smith-Waterman score: 476; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68)
10 20 30 40 50 60
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
::::::::
CCDS33 KFTPQYKGQSQRPLVSWPSLPHFFPWSFPLWPQGSVA
70 80 90
>>CCDS54580.1 IP6K2 gene_id:51447|Hs108|chr3 (185 aa)
initn: 498 init1: 476 opt: 476 Z-score: 536.4 bits: 107.1 E(32554): 1.5e-23
Smith-Waterman score: 476; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:56-123)
10 20 30
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHS
::::::::::::::::::::::::::::::
CCDS54 EGHTDKQQTEDVLAAGLRCLPHLPAICARRMSPAFRAMDVEPRAKGVLLEPFVHQVGGHS
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 CVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGVVSVRFEEDEDRNLCLIAYPLK
::::::::::::::::::::::::::::::::::::::
CCDS54 CVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGKSQLLEGLPHWRGDVRDRGHGR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 GDHGIVDIVDNSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQHRKEEKMKSHKLEEEF
CCDS54 PWQPSLEPSLPPTLCFPSLSSFSSSWPSAQHLTPSVFNPW
150 160 170 180
>>CCDS54581.1 IP6K2 gene_id:51447|Hs108|chr3 (188 aa)
initn: 498 init1: 476 opt: 476 Z-score: 536.2 bits: 107.1 E(32554): 1.5e-23
Smith-Waterman score: 476; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:59-126)
10 20 30
pF1KE3 MSPAFRAMDVEPRAKGVLLEPFVHQVGGHS
::::::::::::::::::::::::::::::
CCDS54 EGHTDKQQTEDVLAAGLRCLPHLPAICARRMSPAFRAMDVEPRAKGVLLEPFVHQVGGHS
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 CVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGVVSVRFEEDEDRNLCLIAYPLK
::::::::::::::::::::::::::::::::::::::
CCDS54 CVLRFNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGKSQLLEGLPHWRGDVRDRGHGR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 GDHGIVDIVDNSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQHRKEEKMKSHKLEEEF
CCDS54 PWQPSLEPSLPPTLCFPSLSSFSSSWPSAQHLTPSVFNPW
150 160 170 180
>>CCDS7250.1 IPMK gene_id:253430|Hs108|chr10 (416 aa)
initn: 460 init1: 214 opt: 303 Z-score: 339.6 bits: 71.9 E(32554): 1.3e-12
Smith-Waterman score: 303; 32.2% identity (67.1% similar) in 146 aa overlap (203-348:127-270)
180 190 200 210 220 230
pF1KE3 LKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDA
.. ::..: ... ::..:.:.: ... :
CCDS72 DCFDGVLLELRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE3 SEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQF
: :: .:. : :: : ::.::.. : . :...::.:. . .:... .:
CCDS72 SSEKIQQQVSK--YPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTKETIKDGVSRF
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE3 FHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDL
:::: ::.. .. ..:. .. .: :.. ::.:::: .:.:. .: .. .:
CCDS72 FHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLA
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE3 EDLSEESADESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQS
CCDS72 EKFLSKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHRKIYTKKHHSQTS
280 290 300 310 320 330
426 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:47:53 2016 done: Mon Nov 7 00:47:53 2016
Total Scan time: 2.910 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]