Result of FASTA (omim) for
pFN21AE3626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3626, 216 aa
1>>>pF1KE3626 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5749+/-0.000481; mu= 12.0691+/- 0.030
mean_var=88.7973+/-17.810, 0's: 0 Z-trim(110.9): 438 B-trim: 976 in 2/50
Lambda= 0.136105
statistics sampled from 18883 (19402) to 18883 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.227), width: 16
Scan time: 5.160
The best scores are: opt bits E(85289)
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 1417 288.5 5.8e-78
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 1191 244.1 1.3e-64
NP_001156852 (OMIM: 607466) ras-related protein Ra ( 170) 1110 228.1 6.8e-60
XP_016877199 (OMIM: 607466) PREDICTED: ras-related ( 171) 1001 206.7 1.9e-53
NP_001229573 (OMIM: 179509) ras-related protein Ra ( 188) 936 194.0 1.4e-49
XP_016877200 (OMIM: 607466) PREDICTED: ras-related ( 151) 920 190.7 1.1e-48
XP_016877201 (OMIM: 607466) PREDICTED: ras-related ( 147) 905 187.8 8e-48
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 803 167.9 1.1e-41
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 728 153.2 3.1e-37
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 713 150.2 2.4e-36
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 645 136.9 2.4e-32
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 631 134.1 1.7e-31
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 628 133.5 2.4e-31
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 612 130.4 2.2e-30
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 608 129.6 3.8e-30
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 601 128.2 9.5e-30
NP_741995 (OMIM: 300774) ras-related protein Rab-3 ( 213) 601 128.2 9.8e-30
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 593 126.6 2.8e-29
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 593 126.6 2.8e-29
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 591 126.2 3.7e-29
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 571 122.3 5.7e-28
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 570 122.2 6.9e-28
NP_001317400 (OMIM: 609956) ras-related protein Ra ( 196) 568 121.7 8.2e-28
NP_001157461 (OMIM: 609956) ras-related protein Ra ( 228) 568 121.8 9.2e-28
NP_783865 (OMIM: 609956) ras-related protein Rab-3 ( 216) 566 121.4 1.2e-27
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 549 118.0 1.1e-26
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 549 118.0 1.1e-26
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 549 118.0 1.1e-26
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 549 118.0 1.1e-26
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 548 117.9 1.5e-26
NP_065120 (OMIM: 612942) ras-related protein Rab-2 ( 213) 544 117.0 2.3e-26
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 532 114.6 1.1e-25
NP_001193765 (OMIM: 605570) ras-related protein Ra ( 155) 517 111.6 7.1e-25
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 513 111.0 1.6e-24
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 513 111.0 1.6e-24
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244) 513 111.0 1.7e-24
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 509 110.1 2.6e-24
NP_001238965 (OMIM: 179514) ras-related protein Ra ( 215) 505 109.4 4.7e-24
XP_005269109 (OMIM: 179514) PREDICTED: ras-related ( 215) 505 109.4 4.7e-24
NP_002859 (OMIM: 179514) ras-related protein Rab-5 ( 215) 505 109.4 4.7e-24
XP_005269108 (OMIM: 179514) PREDICTED: ras-related ( 215) 505 109.4 4.7e-24
NP_004574 (OMIM: 604037) ras-related protein Rab-5 ( 216) 501 108.6 8.1e-24
NP_958842 (OMIM: 604037) ras-related protein Rab-5 ( 216) 501 108.6 8.1e-24
XP_011523393 (OMIM: 604037) PREDICTED: ras-related ( 216) 501 108.6 8.1e-24
XP_011523392 (OMIM: 604037) PREDICTED: ras-related ( 216) 501 108.6 8.1e-24
NP_001238968 (OMIM: 604037) ras-related protein Ra ( 249) 501 108.6 9e-24
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219) 484 105.3 8.3e-23
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219) 484 105.3 8.3e-23
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219) 480 104.5 1.4e-22
NP_004153 (OMIM: 179512) ras-related protein Rab-5 ( 215) 479 104.3 1.6e-22
>>NP_116235 (OMIM: 607466) ras-related protein Rab-2B is (216 aa)
initn: 1417 init1: 1417 opt: 1417 Z-score: 1520.7 bits: 288.5 E(85289): 5.8e-78
Smith-Waterman score: 1417; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHN
130 140 150 160 170 180
190 200 210
pF1KE3 EANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
::::::::::::::::::::::::::::::::::::
NP_116 EANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
190 200 210
>>NP_002856 (OMIM: 179509) ras-related protein Rab-2A is (212 aa)
initn: 1209 init1: 1165 opt: 1191 Z-score: 1280.9 bits: 244.1 E(85289): 1.3e-64
Smith-Waterman score: 1191; 83.8% identity (96.3% similar) in 216 aa overlap (1-216:1-212)
10 20 30 40 50 60
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIW
:.:::::::::::::::::::::::::::::::::::::::::::::..:::::::::::
NP_002 MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK
:::::::::::::::::::::::::::::::.::::::.:::::::::.:::::::::::
NP_002 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHN
:::::::.::.:::::::::::::::::::::: ::::::::::::::.:::.:.::..:
NP_002 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
130 140 150 160 170 180
190 200 210
pF1KE3 EANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
::::::::::.. .... :....... : .:::
NP_002 EANGIKIGPQHAATNAT--HAGNQGGQQAG--GGCC
190 200 210
>>NP_001156852 (OMIM: 607466) ras-related protein Rab-2B (170 aa)
initn: 1110 init1: 1110 opt: 1110 Z-score: 1196.3 bits: 228.1 E(85289): 6.8e-60
Smith-Waterman score: 1110; 100.0% identity (100.0% similar) in 170 aa overlap (47-216:1-170)
20 30 40 50 60 70
pF1KE3 VGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYY
::::::::::::::::::::::::::::::
NP_001 MVNIDGKQIKLQIWDTAGQESFRSITRSYY
10 20 30
80 90 100 110 120 130
pF1KE3 RGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 FAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTS
100 110 120 130 140 150
200 210
pF1KE3 VGPSASQRNSRDIGSNSGCC
::::::::::::::::::::
NP_001 VGPSASQRNSRDIGSNSGCC
160 170
>>XP_016877199 (OMIM: 607466) PREDICTED: ras-related pro (171 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1080.6 bits: 206.7 E(85289): 1.9e-53
Smith-Waterman score: 1001; 100.0% identity (100.0% similar) in 154 aa overlap (63-216:18-171)
40 50 60 70 80 90
pF1KE3 PVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRE
::::::::::::::::::::::::::::::
XP_016 MYANVFIVFIVLTGVPQAGQESFRSITRSYYRGAAGALLVYDITRRE
10 20 30 40
100 110 120 130 140 150
pF1KE3 TFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKT
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 ACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSN
110 120 130 140 150 160
pF1KE3 SGCC
::::
XP_016 SGCC
170
>>NP_001229573 (OMIM: 179509) ras-related protein Rab-2A (188 aa)
initn: 1028 init1: 917 opt: 936 Z-score: 1011.0 bits: 194.0 E(85289): 1.4e-49
Smith-Waterman score: 969; 72.7% identity (85.2% similar) in 216 aa overlap (1-216:1-188)
10 20 30 40 50 60
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIW
:.::::::::::::::: ::::::..:::::::::::
NP_001 MAYAYLFKYIIIGDTGV------------------------EFGARMITIDGKQIKLQIW
10 20 30
70 80 90 100 110 120
pF1KE3 DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNK
:::::::::::::::::::::::::::::::.::::::.:::::::::.:::::::::::
NP_001 DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 SDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHN
:::::::.::.:::::::::::::::::::::: ::::::::::::::.:::.:.::..:
NP_001 SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
100 110 120 130 140 150
190 200 210
pF1KE3 EANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
::::::::::.. .... :....... : .:::
NP_001 EANGIKIGPQHAATNAT--HAGNQGGQQAG--GGCC
160 170 180
>>XP_016877200 (OMIM: 607466) PREDICTED: ras-related pro (151 aa)
initn: 920 init1: 920 opt: 920 Z-score: 995.4 bits: 190.7 E(85289): 1.1e-48
Smith-Waterman score: 920; 95.9% identity (97.3% similar) in 148 aa overlap (69-216:4-151)
40 50 60 70 80 90
pF1KE3 IGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLT
.: .: ::::::::::::::::::::::
XP_016 MENKSNCKSGIRGAAGALLVYDITRRETFNHLT
10 20 30
100 110 120 130 140 150
pF1KE3 SWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 AFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
100 110 120 130 140 150
>>XP_016877201 (OMIM: 607466) PREDICTED: ras-related pro (147 aa)
initn: 905 init1: 905 opt: 905 Z-score: 979.6 bits: 187.8 E(85289): 8e-48
Smith-Waterman score: 905; 100.0% identity (100.0% similar) in 139 aa overlap (78-216:9-147)
50 60 70 80 90 100
pF1KE3 VNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQH
::::::::::::::::::::::::::::::
XP_016 MGTERLIWGAAGALLVYDITRRETFNHLTSWLEDARQH
10 20 30
110 120 130 140 150 160
pF1KE3 SSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEI
40 50 60 70 80 90
170 180 190 200 210
pF1KE3 YRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
100 110 120 130 140
>>NP_057406 (OMIM: 612673) ras-related protein Rab-14 [H (215 aa)
initn: 777 init1: 777 opt: 803 Z-score: 869.1 bits: 167.9 E(85289): 1.1e-41
Smith-Waterman score: 803; 56.7% identity (82.8% similar) in 215 aa overlap (3-216:8-215)
10 20 30 40 50
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQI
:.:.:::::::: :::::::: :::.:.:. :::::::.:.....:..:
NP_057 MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 KLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIM
::::::::::: ::..::::::::::::.::::::: :.:::.::: :::. .. : ::.
NP_057 KLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVII
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 LIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGL
:::::.:::..::: ::.. ::.:.::.:.:.::::. :::.::...::.::..::.:
NP_057 LIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGS
130 140 150 160 170 180
180 190 200 210
pF1KE3 FDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGC-C
.:.. .:.. :. .:.... .:. . :: :
NP_057 LDLNAAESGVQHKPS-------APQGGRLTSEPQPQREGCGC
190 200 210
>>NP_004569 (OMIM: 179511) ras-related protein Rab-4A is (218 aa)
initn: 728 init1: 728 opt: 728 Z-score: 789.4 bits: 153.2 E(85289): 3.1e-37
Smith-Waterman score: 728; 58.3% identity (82.9% similar) in 187 aa overlap (2-188:9-195)
10 20 30 40 50
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGK
:: .:::...::..:.:::::: :: .:.:. . :::::::....:. ::
NP_004 MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMV
.::::::::::: :::.:::::::::::::::::: :::.: ::.:: :::. .:.:.:
NP_004 YVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 IMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQ
:.: :::.::.. :.: :. ::.:. :.:.:::: :. ::::::.. :..: ::..
NP_004 IILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIES
130 140 150 160 170 180
180 190 200 210
pF1KE3 GLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
: .: . ..::. :
NP_004 GELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC
190 200 210
>>NP_057238 (OMIM: 612945) ras-related protein Rab-4B [H (213 aa)
initn: 711 init1: 711 opt: 713 Z-score: 773.7 bits: 150.2 E(85289): 2.4e-36
Smith-Waterman score: 713; 55.0% identity (78.7% similar) in 202 aa overlap (2-203:4-204)
10 20 30 40 50
pF1KE3 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQ
:: .:::...::..:.:::::: :: ...:. . :::::::.:.::. :: .:::
NP_057 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIG
:::::::: :::.:::::::::::::::::: :::.: :..:: ::: .: :.:..: :
NP_057 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDV
::.::. .:.: :. ::.:. :.:.:::: :. ::::::.. :. : ::..: .:
NP_057 NKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDP
130 140 150 160 170 180
180 190 200 210
pF1KE3 HNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
. ..::. : . :. : ..:
NP_057 ERMGSGIQYG-DASLRQLRQPRSAQAVAPQPCGC
190 200 210
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:42:48 2016 done: Mon Nov 7 00:42:49 2016
Total Scan time: 5.160 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]