Result of FASTA (omim) for
pFN21AE3623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3623, 148 aa
1>>>pF1KE3623 148 - 148 aa - 148 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8248+/-0.000293; mu= 14.1696+/- 0.018
mean_var=58.2500+/-11.505, 0's: 0 Z-trim(118.7): 15 B-trim: 0 in 0/49
Lambda= 0.168045
statistics sampled from 31904 (31919) to 31904 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.374), width: 16
Scan time: 4.770
The best scores are: opt bits E(85289)
NP_005847 (OMIM: 605155) receptor activity-modifyi ( 148) 1044 260.5 7.2e-70
XP_006715694 (OMIM: 605155) PREDICTED: receptor ac ( 259) 919 230.3 1.5e-60
XP_016867155 (OMIM: 605155) PREDICTED: receptor ac ( 116) 813 204.4 4.2e-53
NP_005846 (OMIM: 605153) receptor activity-modifyi ( 148) 297 79.4 2.4e-15
XP_016858642 (OMIM: 605153) PREDICTED: receptor ac ( 126) 294 78.6 3.4e-15
XP_016858643 (OMIM: 605153) PREDICTED: receptor ac ( 126) 294 78.6 3.4e-15
XP_016858645 (OMIM: 605153) PREDICTED: receptor ac ( 126) 294 78.6 3.4e-15
NP_001295282 (OMIM: 605153) receptor activity-modi ( 126) 294 78.6 3.4e-15
XP_016858641 (OMIM: 605153) PREDICTED: receptor ac ( 126) 294 78.6 3.4e-15
NP_005845 (OMIM: 605154) receptor activity-modifyi ( 175) 248 67.6 1e-11
>>NP_005847 (OMIM: 605155) receptor activity-modifying p (148 aa)
initn: 1044 init1: 1044 opt: 1044 Z-score: 1375.4 bits: 260.5 E(85289): 7.2e-70
Smith-Waterman score: 1044; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148)
10 20 30 40 50 60
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLI
70 80 90 100 110 120
130 140
pF1KE3 PLIVIPVVLTVAMAGLVVWRSKRTDTLL
::::::::::::::::::::::::::::
NP_005 PLIVIPVVLTVAMAGLVVWRSKRTDTLL
130 140
>>XP_006715694 (OMIM: 605155) PREDICTED: receptor activi (259 aa)
initn: 919 init1: 919 opt: 919 Z-score: 1208.1 bits: 230.3 E(85289): 1.5e-60
Smith-Waterman score: 919; 100.0% identity (100.0% similar) in 129 aa overlap (20-148:131-259)
10 20 30 40
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMG
::::::::::::::::::::::::::::::
XP_006 SLSSGSVPVGHLEGGTVKLQKDTGLHSCRDGGCPRAGGCNETGMLERLPLCGKAFADMMG
110 120 130 140 150 160
50 60 70 80 90 100
pF1KE3 KVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRV
170 180 190 200 210 220
110 120 130 140
pF1KE3 HLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
:::::::::::::::::::::::::::::::::::::::
XP_006 HLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
230 240 250
>>XP_016867155 (OMIM: 605155) PREDICTED: receptor activi (116 aa)
initn: 813 init1: 813 opt: 813 Z-score: 1074.3 bits: 204.4 E(85289): 4.2e-53
Smith-Waterman score: 813; 100.0% identity (100.0% similar) in 116 aa overlap (33-148:1-116)
10 20 30 40 50 60
pF1KE3 TGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEF
::::::::::::::::::::::::::::::
XP_016 MLERLPLCGKAFADMMGKVDVWKWCNLSEF
10 20 30
70 80 90 100 110 120
pF1KE3 IVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPL
40 50 60 70 80 90
130 140
pF1KE3 IVIPVVLTVAMAGLVVWRSKRTDTLL
::::::::::::::::::::::::::
XP_016 IVIPVVLTVAMAGLVVWRSKRTDTLL
100 110
>>NP_005846 (OMIM: 605153) receptor activity-modifying p (148 aa)
initn: 300 init1: 286 opt: 297 Z-score: 396.6 bits: 79.4 E(85289): 2.4e-15
Smith-Waterman score: 297; 34.3% identity (63.5% similar) in 137 aa overlap (14-148:13-148)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
: ::: . .:.:. : : : :: : : : ::.
NP_005 MARALCRLPRRGLWLLLAHHLFMTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
NP_005 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
60 70 80 90 100 110
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
NP_005 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
120 130 140
>>XP_016858642 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 300 init1: 286 opt: 294 Z-score: 393.7 bits: 78.6 E(85289): 3.4e-15
Smith-Waterman score: 294; 35.0% identity (65.9% similar) in 123 aa overlap (28-148:5-126)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
:.:. : : : :: : : : ::.
XP_016 MTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
XP_016 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
40 50 60 70 80 90
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
XP_016 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
100 110 120
>>XP_016858643 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 300 init1: 286 opt: 294 Z-score: 393.7 bits: 78.6 E(85289): 3.4e-15
Smith-Waterman score: 294; 35.0% identity (65.9% similar) in 123 aa overlap (28-148:5-126)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
:.:. : : : :: : : : ::.
XP_016 MTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
XP_016 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
40 50 60 70 80 90
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
XP_016 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
100 110 120
>>XP_016858645 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 300 init1: 286 opt: 294 Z-score: 393.7 bits: 78.6 E(85289): 3.4e-15
Smith-Waterman score: 294; 35.0% identity (65.9% similar) in 123 aa overlap (28-148:5-126)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
:.:. : : : :: : : : ::.
XP_016 MTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
XP_016 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
40 50 60 70 80 90
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
XP_016 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
100 110 120
>>NP_001295282 (OMIM: 605153) receptor activity-modifyin (126 aa)
initn: 300 init1: 286 opt: 294 Z-score: 393.7 bits: 78.6 E(85289): 3.4e-15
Smith-Waterman score: 294; 35.0% identity (65.9% similar) in 123 aa overlap (28-148:5-126)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
:.:. : : : :: : : : ::.
NP_001 MTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
NP_001 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
40 50 60 70 80 90
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
NP_001 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
100 110 120
>>XP_016858641 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 300 init1: 286 opt: 294 Z-score: 393.7 bits: 78.6 E(85289): 3.4e-15
Smith-Waterman score: 294; 35.0% identity (65.9% similar) in 123 aa overlap (28-148:5-126)
10 20 30 40 50
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNET--GMLERLPLCGKAFADMMGKVDVWKWCN
:.:. : : : :: : : : ::.
XP_016 MTTACQEANYGALLR-ELCLTQFQVDMEAVGETLWCD
10 20 30
60 70 80 90 100 110
pF1KE3 LSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV
.. : :. ...:: :. .::.::: .. :. ..: ..: .: .. ..::: .
XP_016 WGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSI
40 50 60 70 80 90
120 130 140
pF1KE3 LIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
: :.::.:...:. ...::::.::::. ..
XP_016 LYPFIVVPITVTLLVTALVVWQSKRTEGIV
100 110 120
>>NP_005845 (OMIM: 605154) receptor activity-modifying p (175 aa)
initn: 285 init1: 224 opt: 248 Z-score: 331.4 bits: 67.6 E(85289): 1e-11
Smith-Waterman score: 248; 28.9% identity (56.3% similar) in 142 aa overlap (4-145:32-172)
10 20 30
pF1KE3 METGALRRPQLLPLLLLLCGGCPRAGGCNETGM
::. :. : : : . : . ..
NP_005 ASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKNY
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 LERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFI
. .: . . :.: .. ::. . . : .. .: : :.. .:::::. .:
NP_005 ETAVQFCWNHYKDQMDPIEK-DWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERII
70 80 90 100 110 120
100 110 120 130 140
pF1KE3 TGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
:. :.::.. . . :::..::. .:. :. : . ::::::: ..
NP_005 FETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA
130 140 150 160 170
148 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:43:06 2016 done: Sun Nov 6 22:43:07 2016
Total Scan time: 4.770 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]