Result of FASTA (omim) for
pFN21AE3617
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3617, 469 aa
1>>>pF1KE3617 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1578+/-0.000408; mu= 18.7437+/- 0.025
mean_var=73.1309+/-14.503, 0's: 0 Z-trim(111.2): 44 B-trim: 0 in 0/53
Lambda= 0.149977
statistics sampled from 19666 (19709) to 19666 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.231), width: 16
Scan time: 8.020
The best scores are: opt bits E(85289)
NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/ ( 469) 3151 691.6 1.2e-198
NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kina ( 462) 3086 677.5 2.1e-194
NP_001304063 (OMIM: 605320) 6-phosphofructo-2-kina ( 498) 2925 642.7 6.8e-184
XP_016862105 (OMIM: 605320) PREDICTED: 6-phosphofr ( 457) 2924 642.4 7.4e-184
NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kina ( 458) 2922 642.0 1e-183
XP_011532131 (OMIM: 605320) PREDICTED: 6-phosphofr ( 471) 2918 641.1 1.9e-183
XP_016862103 (OMIM: 605320) PREDICTED: 6-phosphofr ( 493) 2802 616.1 7e-176
XP_016862106 (OMIM: 605320) PREDICTED: 6-phosphofr ( 453) 2799 615.4 1e-175
NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/ ( 471) 2399 528.8 1.2e-149
XP_005252521 (OMIM: 605319) PREDICTED: 6-phosphofr ( 462) 2247 496.0 9.3e-140
NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kina ( 514) 2236 493.6 5.3e-139
NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/ ( 520) 2236 493.6 5.3e-139
XP_016871814 (OMIM: 605319) PREDICTED: 6-phosphofr ( 568) 2236 493.6 5.7e-139
NP_001304066 (OMIM: 605320) 6-phosphofructo-2-kina ( 434) 2209 487.7 2.7e-137
NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kina ( 494) 2177 480.8 3.6e-135
NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kina ( 500) 2177 480.8 3.6e-135
XP_016871816 (OMIM: 605319) PREDICTED: 6-phosphofr ( 548) 2177 480.9 3.9e-135
NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kina ( 534) 2173 480.0 6.9e-135
NP_001018063 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2151 475.2 1.7e-133
NP_006203 (OMIM: 171835) 6-phosphofructo-2-kinase/ ( 505) 2147 474.3 3.3e-133
XP_016885067 (OMIM: 311790) PREDICTED: 6-phosphofr ( 449) 2140 472.8 8.5e-133
XP_016885065 (OMIM: 311790) PREDICTED: 6-phosphofr ( 500) 2140 472.8 9.2e-133
NP_001258734 (OMIM: 311790) 6-phosphofructo-2-kina ( 406) 2124 469.3 8.7e-132
NP_001258733 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 2018 446.4 7.5e-125
XP_016862104 (OMIM: 605320) PREDICTED: 6-phosphofr ( 463) 1983 438.8 1.5e-122
NP_001304067 (OMIM: 605320) 6-phosphofructo-2-kina ( 278) 1865 413.1 4.8e-115
XP_016885066 (OMIM: 311790) PREDICTED: 6-phosphofr ( 468) 1785 396.0 1.2e-109
XP_011517795 (OMIM: 605319) PREDICTED: 6-phosphofr ( 427) 1529 340.6 5.1e-93
XP_016871817 (OMIM: 605319) PREDICTED: 6-phosphofr ( 533) 1529 340.6 6.1e-93
XP_016871818 (OMIM: 605319) PREDICTED: 6-phosphofr ( 501) 1478 329.6 1.2e-89
XP_016871815 (OMIM: 605319) PREDICTED: 6-phosphofr ( 549) 1478 329.6 1.3e-89
NP_001309946 (OMIM: 605319) 6-phosphofructo-2-kina ( 337) 1422 317.3 4e-86
XP_005273219 (OMIM: 171835) PREDICTED: 6-phosphofr ( 263) 1153 259.1 1.1e-68
>>NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/fruc (469 aa)
initn: 3151 init1: 3151 opt: 3151 Z-score: 3687.1 bits: 691.6 E(85289): 1.2e-198
Smith-Waterman score: 3151; 99.8% identity (100.0% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDYV
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_004 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
370 380 390 400 410 420
430 440 450 460
pF1KE3 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
430 440 450 460
>>NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kinase/f (462 aa)
initn: 2164 init1: 2164 opt: 3086 Z-score: 3611.2 bits: 677.5 E(85289): 2.1e-194
Smith-Waterman score: 3086; 98.3% identity (98.5% similar) in 469 aa overlap (1-469:1-462)
10 20 30 40 50 60
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDYV
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
:::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_001 TSQMKRTIQTAEALGVPYEQWK-------GVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
310 320 330 340 350
370 380 390 400 410 420
pF1KE3 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
360 370 380 390 400 410
430 440 450 460
pF1KE3 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
420 430 440 450 460
>>NP_001304063 (OMIM: 605320) 6-phosphofructo-2-kinase/f (498 aa)
initn: 2914 init1: 2914 opt: 2925 Z-score: 3422.4 bits: 642.7 E(85289): 6.8e-184
Smith-Waterman score: 2925; 98.0% identity (98.7% similar) in 447 aa overlap (23-469:52-498)
10 20 30 40 50
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGK
: .: : .:::::::::::::::::::
NP_001 TGGRVPLGLKAELGQELQQRCAQDRDRKVCRVGLCLCPGTLCMTNCPTLIVMVGLPARGK
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 TYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALR
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE3 DVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 DVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQV
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE3 KLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVAD
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE3 HIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQ
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE3 NIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRD
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE3 QDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPY
390 400 410 420 430 440
420 430 440 450 460
pF1KE3 LKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
450 460 470 480 490
>>XP_016862105 (OMIM: 605320) PREDICTED: 6-phosphofructo (457 aa)
initn: 2921 init1: 2921 opt: 2924 Z-score: 3421.8 bits: 642.4 E(85289): 7.4e-184
Smith-Waterman score: 2924; 98.7% identity (98.9% similar) in 445 aa overlap (27-469:13-457)
10 20 30 40 50
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRG--VCMTNCPTLIVMVGLPARGKTYISKK
: : : ::::::::::::::::::::::::::
XP_016 MRILDPGLKNWAHLFQNGRVVCMTNCPTLIVMVGLPARGKTYISKK
10 20 30 40
60 70 80 90 100 110
pF1KE3 LTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE3 SEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPD
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
XP_016 SEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPD
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 YVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRI
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 VYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE3 VWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRY
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE3 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLH
350 360 370 380 390 400
420 430 440 450 460
pF1KE3 TVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
410 420 430 440 450
>>NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kinase/f (458 aa)
initn: 2922 init1: 2922 opt: 2922 Z-score: 3419.4 bits: 642.0 E(85289): 1e-183
Smith-Waterman score: 2922; 99.5% identity (99.8% similar) in 439 aa overlap (31-469:20-458)
10 20 30 40 50 60
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
: ::::::::::::::::::::::::::::
NP_001 MDRGSLGGSSLTDLGPGSSRRVCMTNCPTLIVMVGLPARGKTYISKKLT
10 20 30 40
70 80 90 100 110 120
pF1KE3 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDYV
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
350 360 370 380 390 400
430 440 450 460
pF1KE3 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
410 420 430 440 450
>>XP_011532131 (OMIM: 605320) PREDICTED: 6-phosphofructo (471 aa)
initn: 2918 init1: 2918 opt: 2918 Z-score: 3414.6 bits: 641.1 E(85289): 1.9e-183
Smith-Waterman score: 2918; 99.8% identity (100.0% similar) in 437 aa overlap (33-469:35-471)
10 20 30 40 50 60
pF1KE3 SPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRY
::::::::::::::::::::::::::::::
XP_011 QQEVLNKHKATEGWDVRESQWCAPRPRHMVVCMTNCPTLIVMVGLPARGKTYISKKLTRY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDYVNR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 GHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLK
370 380 390 400 410 420
430 440 450 460
pF1KE3 LTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
430 440 450 460 470
>>XP_016862103 (OMIM: 605320) PREDICTED: 6-phosphofructo (493 aa)
initn: 2791 init1: 2791 opt: 2802 Z-score: 3278.7 bits: 616.1 E(85289): 7e-176
Smith-Waterman score: 2802; 97.0% identity (97.9% similar) in 434 aa overlap (23-456:52-485)
10 20 30 40 50
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGK
: .: : .:::::::::::::::::::
XP_016 TGGRVPLGLKAELGQELQQRCAQDRDRKVCRVGLCLCPGTLCMTNCPTLIVMVGLPARGK
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 TYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALR
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE3 DVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_016 DVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQV
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE3 KLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVAD
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE3 HIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQ
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE3 NIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRD
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE3 QDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPY
390 400 410 420 430 440
420 430 440 450 460
pF1KE3 LKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
::::::::::::::::::::::::::::::::::::::. ::
XP_016 LKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQGSLWSRVLRLWLLQ
450 460 470 480 490
>>XP_016862106 (OMIM: 605320) PREDICTED: 6-phosphofructo (453 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 3275.7 bits: 615.4 E(85289): 1e-175
Smith-Waterman score: 2799; 98.6% identity (99.1% similar) in 426 aa overlap (31-456:20-445)
10 20 30 40 50 60
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
: ::::::::::::::::::::::::::::
XP_016 MDRGSLGGSSLTDLGPGSSRRVCMTNCPTLIVMVGLPARGKTYISKKLT
10 20 30 40
70 80 90 100 110 120
pF1KE3 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDYV
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_016 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
350 360 370 380 390 400
430 440 450 460
pF1KE3 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
::::::::::::::::::::::::::::::. ::
XP_016 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQGSLWSRVLRLWLLQ
410 420 430 440 450
>>NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/fruc (471 aa)
initn: 2397 init1: 2076 opt: 2399 Z-score: 2807.7 bits: 528.8 E(85289): 1.2e-149
Smith-Waterman score: 2399; 75.4% identity (90.9% similar) in 471 aa overlap (3-468:2-470)
10 20 30 40 50
pF1KE3 MASPR--ELTQNPLKKIWMPYSNGRPALHACQRGVCM---TNCPTLIVMVGLPARGKTYI
::. ::::. :.:::.:.:.: :. .:: . :: ::...::::::::::::
NP_002 MSPEMGELTQTRLQKIWIPHSSGSSRLQR-RRGSSIPQFTNSPTMVIMVGLPARGKTYI
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 SKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVR
: ::::::::::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::.
NP_002 STKLTRYLNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 RFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLG
.::.: ::::::::::::::::. :..:....:::.::.:::: :: .:: :: :::::
NP_002 NYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 SPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQ
::::.. : ... :::..:::::: .:. :::.:: ::::::.::: :.:::: ::::
NP_002 SPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIK
:: :::::::::::::::::::::::::..:::::: ::: ::...: .::.::..:.:.
NP_002 SRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGIS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 DLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDK
.::::::.:::::::::::::::::::.::::::::::::::::::..:: :::::::::
NP_002 SLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKC
::::::::::::::::::::::::::::::::::::::::::::::::::....::::::
NP_002 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKC
360 370 380 390 400 410
420 430 440 450 460
pF1KE3 PLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
::::::::::::::::::::.::: ::::::..:.::::.: ::::: :::::
NP_002 PLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
420 430 440 450 460 470
>>XP_005252521 (OMIM: 605319) PREDICTED: 6-phosphofructo (462 aa)
initn: 2222 init1: 1348 opt: 2247 Z-score: 2630.1 bits: 496.0 E(85289): 9.3e-140
Smith-Waterman score: 2247; 71.4% identity (89.7% similar) in 455 aa overlap (4-456:2-453)
10 20 30 40 50
pF1KE3 MASPRELTQNPLKKIWMPYSNGRPAL-HACQRGVCMTNCPTLIVMVGLPARGKTYISKKL
: ::::. ..:::.: .. ::.: ..: : .:: ::.::::::::::::::::::
XP_005 MPLELTQSRVQKIWVPVDH-RPSLPRSC--GPKLTNSPTVIVMVGLPARGKTYISKKL
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 TRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLS
:::::::::::. ::::.:::..:: :.:..:: :::::..:.::::::::::::. .:.
XP_005 TRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 EEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIMQVKLGSPDY
.:::..::::::::::::: :..:...: .:.::.::.: :: :.:.:::.::..::::
XP_005 KEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 VNRDSDEATEDFMRRIECYENSYESLDED-LDRDLSYIKIMDVGQSYVVNRVADHIQSRI
. .: :: .:::.:: ::: ::. :: : ::::: ::..:::. ..:::: :::::::
XP_005 KDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 VYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLK
::::::::: ::.::::::::.: ::.:::::: ::: ::..::..:..:. .::.:::.
XP_005 VYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 VWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRY
:::::.: :::::::: .::::::.:::::::::::.:::::.:.:: :.:::.:::: :
XP_005 VWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLH
::: ::::.:::::::::::::::::::::::::::.::::::::::.::..::::::::
XP_005 RYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLH
360 370 380 390 400 410
420 430 440 450 460
pF1KE3 TVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
::::::::::::.::::.::: .: :::.: .:. ::
XP_005 TVLKLTPVAYGCRVESIYLNVESVCTHRERSENMKGSRSSADSSRKH
420 430 440 450 460
469 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:24:37 2016 done: Sun Nov 6 20:24:39 2016
Total Scan time: 8.020 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]