Result of FASTA (omim) for
pFN21AE3602
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3602, 495 aa
1>>>pF1KE3602 495 - 495 aa - 495 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5620+/-0.000357; mu= 16.5429+/- 0.022
mean_var=71.6316+/-14.457, 0's: 0 Z-trim(114.0): 85 B-trim: 0 in 0/50
Lambda= 0.151538
statistics sampled from 23477 (23562) to 23477 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.276), width: 16
Scan time: 9.750
The best scores are: opt bits E(85289)
NP_982293 (OMIM: 602012) ectonucleoside triphospha ( 495) 3337 739.0 7.3e-213
NP_001237 (OMIM: 602012) ectonucleoside triphospha ( 472) 2610 580.0 4.9e-165
XP_011517514 (OMIM: 602012) PREDICTED: ectonucleos ( 392) 2480 551.6 1.5e-156
NP_001028285 (OMIM: 616748) ectonucleoside triphos ( 495) 1414 318.6 2.6e-86
XP_011516967 (OMIM: 616748) PREDICTED: ectonucleos ( 603) 1414 318.6 3.1e-86
NP_001278889 (OMIM: 603161) ectonucleoside triphos ( 529) 1324 298.9 2.3e-80
NP_001239 (OMIM: 603161) ectonucleoside triphospha ( 529) 1324 298.9 2.3e-80
NP_001767 (OMIM: 601752,615683) ectonucleoside tri ( 510) 1228 277.9 4.7e-74
XP_011538673 (OMIM: 601752,615683) PREDICTED: ecto ( 517) 1228 277.9 4.8e-74
NP_001091645 (OMIM: 601752,615683) ectonucleoside ( 517) 1228 277.9 4.8e-74
NP_001157650 (OMIM: 601752,615683) ectonucleoside ( 522) 1228 277.9 4.8e-74
XP_011538672 (OMIM: 601752,615683) PREDICTED: ecto ( 529) 1208 273.5 1e-72
NP_001278890 (OMIM: 603161) ectonucleoside triphos ( 452) 1195 270.7 6.3e-72
XP_016872447 (OMIM: 601752,615683) PREDICTED: ecto ( 470) 1090 247.7 5.3e-65
NP_001307845 (OMIM: 601752,615683) ectonucleoside ( 482) 1090 247.7 5.5e-65
NP_940987 (OMIM: 616748) ectonucleoside triphospha ( 458) 1077 244.9 3.7e-64
XP_011516968 (OMIM: 616748) PREDICTED: ectonucleos ( 566) 1077 244.9 4.5e-64
XP_011538674 (OMIM: 601752,615683) PREDICTED: ecto ( 489) 1070 243.4 1.1e-63
XP_011538675 (OMIM: 601752,615683) PREDICTED: ecto ( 481) 1064 242.0 2.8e-63
XP_011538676 (OMIM: 601752,615683) PREDICTED: ecto ( 469) 1063 241.8 3.2e-63
XP_011516970 (OMIM: 616748) PREDICTED: ectonucleos ( 368) 1021 232.6 1.5e-60
NP_001299583 (OMIM: 601752,615683) ectonucleoside ( 402) 968 221.0 5e-57
NP_001157653 (OMIM: 601752,615683) ectonucleoside ( 402) 968 221.0 5e-57
XP_011538679 (OMIM: 601752,615683) PREDICTED: ecto ( 402) 968 221.0 5e-57
XP_011538678 (OMIM: 601752,615683) PREDICTED: ecto ( 430) 941 215.1 3.2e-55
XP_016872448 (OMIM: 601752,615683) PREDICTED: ecto ( 372) 852 195.6 2e-49
NP_001157654 (OMIM: 601752,615683) ectonucleoside ( 372) 852 195.6 2e-49
NP_001157655 (OMIM: 601752,615683) ectonucleoside ( 372) 852 195.6 2e-49
XP_016872449 (OMIM: 601752,615683) PREDICTED: ecto ( 362) 830 190.8 5.5e-48
XP_011532568 (OMIM: 603161) PREDICTED: ectonucleos ( 283) 792 182.5 1.4e-45
XP_016872453 (OMIM: 601752,615683) PREDICTED: ecto ( 276) 782 180.3 6.3e-45
XP_016872452 (OMIM: 601752,615683) PREDICTED: ecto ( 288) 782 180.3 6.6e-45
NP_001157651 (OMIM: 601752,615683) ectonucleoside ( 469) 782 180.4 9.9e-45
XP_016872451 (OMIM: 601752,615683) PREDICTED: ecto ( 295) 762 175.9 1.4e-43
XP_016872450 (OMIM: 601752,615683) PREDICTED: ecto ( 332) 714 165.4 2.2e-40
NP_065087 (OMIM: 616753) ectonucleoside triphospha ( 604) 326 80.7 1.3e-14
XP_016877306 (OMIM: 603162) PREDICTED: ectonucleos ( 360) 309 76.9 1.1e-13
XP_006720389 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 309 76.9 1.1e-13
XP_016877305 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 309 76.9 1.1e-13
NP_001308913 (OMIM: 603162) ectonucleoside triphos ( 405) 309 76.9 1.2e-13
XP_006720388 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 309 76.9 1.2e-13
NP_001317118 (OMIM: 603162) ectonucleoside triphos ( 407) 309 76.9 1.2e-13
XP_016877303 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 309 76.9 1.2e-13
XP_005268281 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 309 77.0 1.2e-13
NP_001240 (OMIM: 603162) ectonucleoside triphospha ( 428) 309 77.0 1.2e-13
NP_001308915 (OMIM: 603162) ectonucleoside triphos ( 428) 309 77.0 1.2e-13
NP_001308914 (OMIM: 603162) ectonucleoside triphos ( 428) 309 77.0 1.2e-13
XP_016877302 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 309 77.0 1.2e-13
NP_001308916 (OMIM: 603162) ectonucleoside triphos ( 428) 309 77.0 1.2e-13
NP_001308917 (OMIM: 603162) ectonucleoside triphos ( 428) 309 77.0 1.2e-13
>>NP_982293 (OMIM: 602012) ectonucleoside triphosphate d (495 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 3942.5 bits: 739.0 E(85289): 7.3e-213
Smith-Waterman score: 3337; 99.8% identity (100.0% similar) in 495 aa overlap (1-495:1-495)
10 20 30 40 50 60
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNTSARVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_982 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
430 440 450 460 470 480
490
pF1KE3 LLLRQVHSAKLPSTI
:::::::::::::::
NP_982 LLLRQVHSAKLPSTI
490
>>NP_001237 (OMIM: 602012) ectonucleoside triphosphate d (472 aa)
initn: 2608 init1: 2608 opt: 2610 Z-score: 3083.8 bits: 580.0 E(85289): 4.9e-165
Smith-Waterman score: 3124; 95.2% identity (95.4% similar) in 495 aa overlap (1-495:1-472)
10 20 30 40 50 60
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNTSARVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_001 LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF
::::::::::::::::::::::: ::::::::::::::
NP_001 LPVATLQQLEAAAVNVCNQTWAQ-----------------------QLLSRGYGFDERAF
370 380 390
430 440 450 460 470 480
pF1KE3 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
400 410 420 430 440 450
490
pF1KE3 LLLRQVHSAKLPSTI
:::::::::::::::
NP_001 LLLRQVHSAKLPSTI
460 470
>>XP_011517514 (OMIM: 602012) PREDICTED: ectonucleoside (392 aa)
initn: 2473 init1: 2473 opt: 2480 Z-score: 2931.5 bits: 551.6 E(85289): 1.5e-156
Smith-Waterman score: 2480; 95.9% identity (97.4% similar) in 387 aa overlap (109-495:12-392)
80 90 100 110 120 130
pF1KE3 GGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTS
.: .. ::: :. .: :::::::::
XP_011 MPRTGASGCAQRETRGHTPLP-GSHSG-----LTNPEASTS
10 20 30
140 150 160 170 180 190
pF1KE3 VLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 AMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 THGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLF
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 THGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLF
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE3 SFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCN
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE3 QTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWAL
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE3 GYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
340 350 360 370 380 390
>>NP_001028285 (OMIM: 616748) ectonucleoside triphosphat (495 aa)
initn: 1272 init1: 614 opt: 1414 Z-score: 1670.4 bits: 318.6 E(85289): 2.6e-86
Smith-Waterman score: 1414; 44.1% identity (74.3% similar) in 483 aa overlap (13-486:13-490)
10 20 30 40 50
pF1KE3 MAGKVRSLLPPLLLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYK
::.:.:..:: .:: : . .: : .:.:::.::::::::.:.:.
NP_001 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 WPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPL
: :.::: ::.:.: .:.: : :::::..: . :..:: ::::.:: .:. .: ::
NP_001 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 YLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLL
.::::::::::. : . ... :::..: . : :: ::..:.:: ::.:::.:.:: :
NP_001 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 ENFIKYGWVGRWFRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVY
...::...:.:..: . : ::.:.::::::::: .: :........:::. : ::
NP_001 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 THSFLCYGRDQVLQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQN
:::.::.::::.:.:::.. .:.. :::. :..: . :: .:.:::. : :
NP_001 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPP--
250 260 270 280 290
300 310 320 330 340 350
pF1KE3 FNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYT
.. ... :...: : . . ::.:::: .. :.:.::.:::. :.: ::: :.::
NP_001 LSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 VDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSR
:: . :..:.. :. . :.. : ..: ::: : ::::..... :: .
NP_001 FHFLNLTSRQPLSTVN---ATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHE
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 GYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLF
::::.:... .. :.:.:. . .::.::::::::..:::: :. .. ... ::. ....
NP_001 GYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFM
420 430 440 450 460 470
480 490
pF1KE3 ASALLAALVLLLRQVHSAKLPSTI
. ::.:.. : :.
NP_001 VLALVAVVGAALVQLFWLQD
480 490
>>XP_011516967 (OMIM: 616748) PREDICTED: ectonucleoside (603 aa)
initn: 1272 init1: 614 opt: 1414 Z-score: 1669.1 bits: 318.6 E(85289): 3.1e-86
Smith-Waterman score: 1414; 44.1% identity (74.3% similar) in 483 aa overlap (13-486:121-598)
10 20 30
pF1KE3 MAGKVRSLLPPLLLAAAGLAGL---LLLCVPTRDVREPPALK
::.:.:..:: .:: : . .: : .:
XP_011 RVPLSTCPGAPGTSTTCTMGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIK
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE3 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGC
.:::.::::::::.:.:.: :.::: ::.:.: .:.: : :::::..: . :..:: ::
XP_011 FGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGC
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE3 LEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARI
::.:: .:. .: :: .::::::::::. : . ... :::..: . : :: ::..
XP_011 LEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAEL
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE3 LSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTL-GAMDLGGASTQITFETTSPAE
:.:: ::.:::.:.:: : ...::...:.:..: . : ::.:.::::::::: .:
XP_011 LAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPIL
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE3 DRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGF----HPCWPRGFSTQV
:........:::. : :::::.::.::::.:.:::.. .:.. :::. :..: .
XP_011 DKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTL
340 350 360 370 380 390
280 290 300 310 320 330
pF1KE3 LLGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGV
:: .:.:::. : : .. ... :...: : . . ::.:::: .. :.:.::
XP_011 ALGPLYESPCVHATPP--LSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGV
400 410 420 430 440
340 350 360 370 380 390
pF1KE3 FQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRA
.:::. :.: ::: :.:: :: . :..:.. :. . :.. : ..: :::
XP_011 YQPPLRGQFYAFSNFYYTFHFLNLTSRQPLSTVN---ATIWEFCQRPWKLVEASYPGQDR
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE3 RLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPP
: ::::..... :: .::::.:... .. :.:.:. . .::.::::::::..:::: :
XP_011 WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAP
510 520 530 540 550 560
460 470 480 490
pF1KE3 GLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
. .. ... ::. ..... ::.:.. : :.
XP_011 AQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD
570 580 590 600
>>NP_001278889 (OMIM: 603161) ectonucleoside triphosphat (529 aa)
initn: 1262 init1: 602 opt: 1324 Z-score: 1563.6 bits: 298.9 E(85289): 2.3e-80
Smith-Waterman score: 1324; 41.5% identity (74.0% similar) in 480 aa overlap (12-482:30-505)
10 20 30 40
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGI
::.. . :... .. . ..: ::.:::::
NP_001 MFTVLTRQPCEQAGLKALYRTPTIIALVVLLVSIVVLVSITVIQIHKQEVL-PPGLKYGI
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 VLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQ
:::::::.:....:.:::.:::.::.:.: .:.: :.:::::..::. . ... :...
NP_001 VLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 ALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSG
. .::.. :..::..:::::::::: : : :.. :: .. . . :::::::.:.::
NP_001 VKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPFDFRGAQIISG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 QEEGVFGWVTANYLLENFIKYGWVGRWFRPRK-GTLGAMDLGGASTQITFETTSPAEDRA
:::::.::.:::::. ::.. . : .:. : ::.:::::::::.: . . .
NP_001 QEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNT
180 190 200 210 220 230
230 240 250 260 270
pF1KE3 SEV-QLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQT-----HGFHPCWPRGFSTQVL
:.. :. ::: : .::::: ::::... ...:: ::. : .::.:: .: .
NP_001 SDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 LGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGVF
.: :..: ::. :::...: . ... :..:: ::.. :...:.:..: .. :::.::.
NP_001 MGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVY
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 QPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPG-QRA
:: . : ::::..:.::.. : : .. .:. ..... : :.:.:.:: .: ...
NP_001 QPKIKGPFVAFAGFYYTASALNLSGSF---SLDTFNSSTWNFCSQNWSQLPLLLPKFDEV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 RLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPP
.:: .: .. .:. :: : :... . :.:........:.:::::.::: :::. :
NP_001 YARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESP
420 430 440 450 460 470
460 470 480 490
pF1KE3 GLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
.: . .: : .:..: : :..:
NP_001 LIRLPIEPPVFVGTLAFFTAAALLCLAFLAYLCSATRRKRHSEHAFDHAVDSD
480 490 500 510 520
>>NP_001239 (OMIM: 603161) ectonucleoside triphosphate d (529 aa)
initn: 1262 init1: 602 opt: 1324 Z-score: 1563.6 bits: 298.9 E(85289): 2.3e-80
Smith-Waterman score: 1324; 41.5% identity (74.0% similar) in 480 aa overlap (12-482:30-505)
10 20 30 40
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGI
::.. . :... .. . ..: ::.:::::
NP_001 MFTVLTRQPCEQAGLKALYRTPTIIALVVLLVSIVVLVSITVIQIHKQEVL-PPGLKYGI
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 VLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQ
:::::::.:....:.:::.:::.::.:.: .:.: :.:::::..::. . ... :...
NP_001 VLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 ALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSG
. .::.. :..::..:::::::::: : : :.. :: .. . . :::::::.:.::
NP_001 VKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPFDFRGAQIISG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 QEEGVFGWVTANYLLENFIKYGWVGRWFRPRK-GTLGAMDLGGASTQITFETTSPAEDRA
:::::.::.:::::. ::.. . : .:. : ::.:::::::::.: . . .
NP_001 QEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNT
180 190 200 210 220 230
230 240 250 260 270
pF1KE3 SEV-QLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQT-----HGFHPCWPRGFSTQVL
:.. :. ::: : .::::: ::::... ...:: ::. : .::.:: .: .
NP_001 SDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 LGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGVF
.: :..: ::. :::...: . ... :..:: ::.. :...:.:..: .. :::.::.
NP_001 MGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVY
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 QPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPG-QRA
:: . : ::::..:.::.. : : .. .:. ..... : :.:.:.:: .: ...
NP_001 QPKIKGPFVAFAGFYYTASALNLSGSF---SLDTFNSSTWNFCSQNWSQLPLLLPKFDEV
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 RLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPP
.:: .: .. .:. :: : :... . :.:........:.:::::.::: :::. :
NP_001 YARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESP
420 430 440 450 460 470
460 470 480 490
pF1KE3 GLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
.: . .: : .:..: : :..:
NP_001 LIRLPIEPPVFVGTLAFFTAAALLCLAFLAYLCSATRRKRHSEHAFDHAVDSD
480 490 500 510 520
>>NP_001767 (OMIM: 601752,615683) ectonucleoside triphos (510 aa)
initn: 1158 init1: 564 opt: 1228 Z-score: 1450.4 bits: 277.9 E(85289): 4.7e-74
Smith-Waterman score: 1228; 40.0% identity (67.8% similar) in 500 aa overlap (5-487:9-500)
10 20 30 40 50
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLL----LLCVP-TRDVREPPALKYGIVLDAGSSHT
:... .:: :..... :: : :.. : .:::::::::::::
NP_001 MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 SMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKER
:..::::::.::::::.: : : : : :::..... . . :. :.:.: . .:. .
NP_001 SLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 HAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWV
: ::.::::::::::: . . : . :: .: ..:..:::::.::::..:::::..::.
NP_001 HQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWI
130 140 150 160 170 180
180 190 200 210 220
pF1KE3 TANYLLENFIKYGWVGRWFR--PRKG----TLGAMDLGGASTQITF-ETTSPAEDRASEV
: :::: :.. ::: : . :.::.::::::::.:: .. :. . .
NP_001 TINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNAL
190 200 210 220 230
230 240 250 260 270 280
pF1KE3 QLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQVLLGDVY
:..:::. : ::::::::::.::.: . ::. .:. . . ::. :.. : ..:.:
NP_001 QFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLY
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 QSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAG
..::: .: . . ..: .. . :.. . ::. : ::.:.:.:::.: ::. :
NP_001 KTPCT--KRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQG
300 310 320 330 340 350
350 360 370 380 390
pF1KE3 NFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRAR-LADYC
.: :::::.... :: .. .. ... . : : : .... : . . :..::
NP_001 DFGAFSAFYFVMKFL--NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 AGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGT
.. .. .:: .:: : .. . : : . .::.:::::::::.:::. : :
NP_001 FSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQP-LSTPL
420 430 440 450 460 470
460 470 480 490
pF1KE3 DFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
. :..: :..::. .:... .. : :
NP_001 SHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV
480 490 500 510
>>XP_011538673 (OMIM: 601752,615683) PREDICTED: ectonucl (517 aa)
initn: 1158 init1: 564 opt: 1228 Z-score: 1450.4 bits: 277.9 E(85289): 4.8e-74
Smith-Waterman score: 1228; 40.0% identity (67.8% similar) in 500 aa overlap (5-487:16-507)
10 20 30 40
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLL----LLCVP-TRDVREPPALKYGIVL
:... .:: :..... :: : :.. : .::::::
XP_011 MKGTKDLTSQQKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 DAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQAL
::::::::..::::::.::::::.: : : : : :::..... . . :. :.:.:
XP_011 DAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQE
. .:. .: ::.::::::::::: . . : . :: .: ..:..:::::.::::..:::
XP_011 EVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQE
130 140 150 160 170 180
170 180 190 200 210
pF1KE3 EGVFGWVTANYLLENFIKYGWVGRWFR--PRKG----TLGAMDLGGASTQITF-ETTSPA
::..::.: :::: :.. ::: : . :.::.::::::::.:: ..
XP_011 EGAYGWITINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTI
190 200 210 220 230
220 230 240 250 260 270
pF1KE3 EDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQ
:. . .:..:::. : ::::::::::.::.: . ::. .:. . . ::. :..
XP_011 ESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 VLLGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGV
: ..:.:..::: .: . . ..: .. . :.. . ::. : ::.:.:.:::.
XP_011 VNVSDLYKTPCT--KRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 FQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRA
: ::. :.: :::::.... :: .. .. ... . : : : .... : .
XP_011 FLPPLQGDFGAFSAFYFVMKFL--NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 R-LADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADP
. :..:: .. .. .:: .:: : .. . : : . .::.:::::::::.:::.
XP_011 KYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQ
420 430 440 450 460 470
460 470 480 490
pF1KE3 PGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
: : . :..: :..::. .:... .. : :
XP_011 P-LSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV
480 490 500 510
>>NP_001091645 (OMIM: 601752,615683) ectonucleoside trip (517 aa)
initn: 1158 init1: 564 opt: 1228 Z-score: 1450.4 bits: 277.9 E(85289): 4.8e-74
Smith-Waterman score: 1228; 40.0% identity (67.8% similar) in 500 aa overlap (5-487:16-507)
10 20 30 40
pF1KE3 MAGKVRSLLPPLLLAAAGLAGLL----LLCVP-TRDVREPPALKYGIVL
:... .:: :..... :: : :.. : .::::::
NP_001 MKGTKDLTSQQKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 DAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQAL
::::::::..::::::.::::::.: : : : : :::..... . . :. :.:.:
NP_001 DAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQE
. .:. .: ::.::::::::::: . . : . :: .: ..:..:::::.::::..:::
NP_001 EVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQE
130 140 150 160 170 180
170 180 190 200 210
pF1KE3 EGVFGWVTANYLLENFIKYGWVGRWFR--PRKG----TLGAMDLGGASTQITF-ETTSPA
::..::.: :::: :.. ::: : . :.::.::::::::.:: ..
NP_001 EGAYGWITINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTI
190 200 210 220 230
220 230 240 250 260 270
pF1KE3 EDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFH----PCWPRGFSTQ
:. . .:..:::. : ::::::::::.::.: . ::. .:. . . ::. :..
NP_001 ESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 VLLGDVYQSPCTMAQRPQNFNTSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGV
: ..:.:..::: .: . . ..: .. . :.. . ::. : ::.:.:.:::.
NP_001 VNVSDLYKTPCT--KRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 FQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRA
: ::. :.: :::::.... :: .. .. ... . : : : .... : .
NP_001 FLPPLQGDFGAFSAFYFVMKFL--NLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 R-LADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADP
. :..:: .. .. .:: .:: : .. . : : . .::.:::::::::.:::.
NP_001 KYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQ
420 430 440 450 460 470
460 470 480 490
pF1KE3 PGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI
: : . :..: :..::. .:... .. : :
NP_001 P-LSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV
480 490 500 510
495 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:39:41 2016 done: Sat Nov 5 23:39:43 2016
Total Scan time: 9.750 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]