Result of FASTA (omim) for
pFN21AE3601
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3601, 179 aa
1>>>pF1KE3601 179 - 179 aa - 179 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0030+/-0.00031; mu= 14.9098+/- 0.019
mean_var=62.6818+/-12.429, 0's: 0 Z-trim(116.8): 128 B-trim: 322 in 1/51
Lambda= 0.161996
statistics sampled from 28108 (28242) to 28108 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.331), width: 16
Scan time: 5.850
The best scores are: opt bits E(85289)
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 1197 287.6 7.3e-78
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 947 229.1 2.3e-60
NP_861516 (OMIM: 605574) ubiquitin-conjugating enz ( 150) 724 177.0 1.2e-44
NP_861515 (OMIM: 605574) ubiquitin-conjugating enz ( 161) 483 120.7 1.1e-27
NP_001268671 (OMIM: 605574) ubiquitin-conjugating ( 79) 473 118.2 3.2e-27
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 411 103.9 1.3e-22
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 408 103.2 2.1e-22
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 366 93.3 1.9e-19
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 362 92.4 3.4e-19
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 356 90.9 7.7e-19
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 347 88.9 3.9e-18
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 345 88.4 5.4e-18
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 345 88.4 5.4e-18
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 340 87.3 1.6e-17
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 340 87.3 1.6e-17
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 340 87.3 1.6e-17
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 340 87.3 1.6e-17
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 340 87.3 1.6e-17
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 337 86.6 2e-17
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 338 86.9 2.2e-17
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 338 86.9 2.2e-17
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 335 86.1 3.1e-17
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 330 84.9 6.6e-17
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 325 83.8 1.7e-16
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 323 83.3 2.1e-16
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 323 83.3 2.3e-16
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 323 83.4 2.4e-16
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 309 80.1 2.4e-15
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 304 78.8 3.5e-15
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 303 78.5 4.1e-15
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 303 78.5 4.1e-15
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 305 79.1 4.2e-15
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 294 76.6 2.4e-14
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 286 74.7 8.5e-14
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 286 74.7 9.2e-14
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 284 74.2 1.1e-13
NP_001268670 (OMIM: 605574) ubiquitin-conjugating ( 132) 279 73.0 2.2e-13
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 278 72.7 2.2e-13
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 277 72.6 4.6e-13
NP_001257944 (OMIM: 614277) ubiquitin-conjugating ( 188) 276 72.4 4.7e-13
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 273 71.5 4.9e-13
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 274 71.8 5.7e-13
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 274 71.8 5.7e-13
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 274 71.8 5.7e-13
>>NP_008950 (OMIM: 605574) ubiquitin-conjugating enzyme (179 aa)
initn: 1197 init1: 1197 opt: 1197 Z-score: 1518.9 bits: 287.6 E(85289): 7.3e-78
Smith-Waterman score: 1197; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
130 140 150 160 170
>>NP_861517 (OMIM: 605574) ubiquitin-conjugating enzyme (140 aa)
initn: 947 init1: 947 opt: 947 Z-score: 1204.7 bits: 229.1 E(85289): 2.3e-60
Smith-Waterman score: 947; 100.0% identity (100.0% similar) in 140 aa overlap (40-179:1-140)
10 20 30 40 50 60
pF1KE3 ATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGA
::::::::::::::::::::::::::::::
NP_861 MTLMMSGDKGISAFPESDNLFKWVGTIHGA
10 20 30
70 80 90 100 110 120
pF1KE3 AGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 AGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVR
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 TILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 TILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
100 110 120 130 140
>>NP_861516 (OMIM: 605574) ubiquitin-conjugating enzyme (150 aa)
initn: 985 init1: 724 opt: 724 Z-score: 922.6 bits: 177.0 E(85289): 1.2e-44
Smith-Waterman score: 930; 83.8% identity (83.8% similar) in 179 aa overlap (1-179:1-150)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
:::::::::::::::::::::::::::::::::::::::::::
NP_861 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLM-----------------
10 20 30 40
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 ------------VYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
50 60 70 80 90
130 140 150 160 170
pF1KE3 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
100 110 120 130 140 150
>>NP_861515 (OMIM: 605574) ubiquitin-conjugating enzyme (161 aa)
initn: 732 init1: 483 opt: 483 Z-score: 617.7 bits: 120.7 E(85289): 1.1e-27
Smith-Waterman score: 714; 67.6% identity (76.9% similar) in 182 aa overlap (1-179:1-161)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
::::::::::::. ..: . .. . :: . . : :.
NP_861 KWVGTIHGAAGTAVGSIRTSSTVCLLSGPRETQDSSKPLV--------------------
70 80 90 100
130 140 150 160 170
pF1KE3 KWSALYDVRTIL-LSIQSLLG--EPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQ
:. .:.: .: :..: .: :::::::::::::::::::::::::::::::::::::
NP_861 -WGLGWDMRLLLELTLQLFLQMPEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQ
110 120 130 140 150
pF1KE3 EP
::
NP_861 EP
160
>>NP_001268671 (OMIM: 605574) ubiquitin-conjugating enzy (79 aa)
initn: 473 init1: 473 opt: 473 Z-score: 609.6 bits: 118.2 E(85289): 3.2e-27
Smith-Waterman score: 473; 100.0% identity (100.0% similar) in 72 aa overlap (1-72:1-72)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
::::::::::::
NP_001 KWVGTIHGAAGTNPTLIVP
70
>>NP_003328 (OMIM: 179095) ubiquitin-conjugating enzyme (152 aa)
initn: 346 init1: 331 opt: 411 Z-score: 527.2 bits: 103.9 E(85289): 1.3e-22
Smith-Waterman score: 411; 44.9% identity (72.8% similar) in 136 aa overlap (30-164:4-139)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
:. .::.... :. . :.:. : .:..
NP_003 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIM
10 20 30
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
.: ..: : :: .:: .:: .:: :: . :::.::. .:::: ..:.::::::..
NP_003 QWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWK-NPTAFKKYLQETYSKQVTSQEP
.:: ::: .:: :::::: ::: .:: :..::.:.. : ..:
NP_003 RWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
100 110 120 130 140 150
>>NP_003327 (OMIM: 300860,312180) ubiquitin-conjugating (152 aa)
initn: 347 init1: 331 opt: 408 Z-score: 523.4 bits: 103.2 E(85289): 2.1e-22
Smith-Waterman score: 408; 44.1% identity (72.8% similar) in 136 aa overlap (30-164:4-139)
10 20 30 40 50 60
pF1KE3 MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLF
:. .::.... :. . :.:. : .:..
NP_003 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIM
10 20 30
70 80 90 100 110 120
pF1KE3 KWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKE
: ..: : :: .:: .::..:: :: . :::.:.. .:::: ..:.::::::..
NP_003 VWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 KWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWK-NPTAFKKYLQETYSKQVTSQEP
.:: ::: .:: :::::: ::: .:: :..::.:.. : ..:
NP_003 RWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
100 110 120 130 140 150
>>NP_003339 (OMIM: 603679) ubiquitin-conjugating enzyme (152 aa)
initn: 351 init1: 318 opt: 366 Z-score: 470.3 bits: 93.3 E(85289): 1.9e-19
Smith-Waterman score: 366; 45.0% identity (65.9% similar) in 129 aa overlap (33-161:6-134)
10 20 30 40 50 60
pF1KE3 SQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKW
.:. .: . :. ::.: :. .: .
NP_003 MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYF
10 20 30
70 80 90 100 110 120
pF1KE3 VGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKW
.: : . .: .:: : .: ::. :: :.:.: :::::: : :::::::.::
NP_003 HVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKW
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 SALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
: ..::.:::::.::. :: :.:: . .:: ::. :
NP_003 SPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
100 110 120 130 140 150
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 349 init1: 349 opt: 362 Z-score: 465.5 bits: 92.4 E(85289): 3.4e-19
Smith-Waterman score: 362; 39.0% identity (66.7% similar) in 141 aa overlap (33-172:4-144)
10 20 30 40 50 60
pF1KE3 SQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKW
::.:.:: :. . :: : .:.::.:
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHW
10 20 30
70 80 90 100 110 120
pF1KE3 VGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKW
.:: : ..:. . :...::. ::.. : . : : ::::....:.::::::. .:
NP_003 QATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQW
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 SALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWK-NPTAFKKYLQETYSKQVTSQEP
: : .:::: ::: .:: :.:: :...: . .... .: .:
NP_003 SPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM
100 110 120 130 140
>>NP_001269090 (OMIM: 300860,312180) ubiquitin-conjugati (119 aa)
initn: 331 init1: 331 opt: 356 Z-score: 459.2 bits: 90.9 E(85289): 7.7e-19
Smith-Waterman score: 356; 50.0% identity (75.0% similar) in 104 aa overlap (62-164:3-106)
40 50 60 70 80 90
pF1KE3 GKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPY
: ..: : :: .:: .::..:: ::
NP_001 MVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPN
10 20 30
100 110 120 130 140 150
pF1KE3 NAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTH
. :::.:.. .:::: ..:.::::::...:: ::: .:: :::::: ::: .:: :..
NP_001 KPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQ
40 50 60 70 80 90
160 170
pF1KE3 AAELWK-NPTAFKKYLQETYSKQVTSQEP
::.:.. : ..:
NP_001 AAQLYQENKREYEKRVSAIVEQSWRDC
100 110
179 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:49:28 2016 done: Sun Nov 6 22:49:29 2016
Total Scan time: 5.850 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]