FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3592, 248 aa
  1>>>pF1KE3592 248 - 248 aa - 248 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9811+/-0.000275; mu= 5.5259+/- 0.017
 mean_var=182.6028+/-35.733, 0's: 0 Z-trim(125.2): 7  B-trim: 86 in 1/61
 Lambda= 0.094912
 statistics sampled from 48394 (48407) to 48394 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.568), width:  16
 Scan time:  8.150

The best scores are:                                      opt bits E(85289)
NP_653274 (OMIM: 607885) CKLF-like MARVEL transmem ( 248) 1718 246.0 4.6e-65
NP_001186246 (OMIM: 607885) CKLF-like MARVEL trans ( 195)  695 105.9 5.6e-23
NP_443725 (OMIM: 607884) CKLF-like MARVEL transmem ( 286)  223 41.4  0.0021


>>NP_653274 (OMIM: 607885) CKLF-like MARVEL transmembran  (248 aa)
 initn: 1718 init1: 1718 opt: 1718  Z-score: 1289.1  bits: 246.0 E(85289): 4.6e-65
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)

               10        20        30        40        50        60
pF1KE3 MAPKAAKGAKPEPAPAPPPPGAKPEEDKKDGKEPSDKPQKAVQDHKEPSDKPQKAVQPKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MAPKAAKGAKPEPAPAPPPPGAKPEEDKKDGKEPSDKPQKAVQDHKEPSDKPQKAVQPKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 EVGTRRGCRRYRWELKDSNKEFWLLGHAEIKIRSLGCLIAAMILLSSLTVHPILRLIITM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 EVGTRRGCRRYRWELKDSNKEFWLLGHAEIKIRSLGCLIAAMILLSSLTVHPILRLIITM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 EISFFSFFILLYSFAIHRYIPFILWPISDLFNDLIACAFLVGAVVFAVRSRRSMNLHYLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 EISFFSFFILLYSFAIHRYIPFILWPISDLFNDLIACAFLVGAVVFAVRSRRSMNLHYLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AVILIGAAGVFAFIDVCLQRNHFRGKKAKKHMLVPPPGKEKGPQQGKGPEPAKPPEPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 AVILIGAAGVFAFIDVCLQRNHFRGKKAKKHMLVPPPGKEKGPQQGKGPEPAKPPEPGKP
              190       200       210       220       230       240

               
pF1KE3 PGPAKGKK
       ::::::::
NP_653 PGPAKGKK
               

>>NP_001186246 (OMIM: 607885) CKLF-like MARVEL transmemb  (195 aa)
 initn: 1360 init1: 695 opt: 695  Z-score: 533.5  bits: 105.9 E(85289): 5.6e-23
Smith-Waterman score: 1258; 78.6% identity (78.6% similar) in 248 aa overlap (1-248:1-195)

               10        20        30        40        50        60
pF1KE3 MAPKAAKGAKPEPAPAPPPPGAKPEEDKKDGKEPSDKPQKAVQDHKEPSDKPQKAVQPKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPKAAKGAKPEPAPAPPPPGAKPEEDKKDGKEPSDKPQKAVQDHKEPSDKPQKAVQPKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 EVGTRRGCRRYRWELKDSNKEFWLLGHAEIKIRSLGCLIAAMILLSSLTVHPILRLIITM
       :::::::::::::::::::::::::::::::::::                         
NP_001 EVGTRRGCRRYRWELKDSNKEFWLLGHAEIKIRSL-------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KE3 EISFFSFFILLYSFAIHRYIPFILWPISDLFNDLIACAFLVGAVVFAVRSRRSMNLHYLL
                                   ::::::::::::::::::::::::::::::::
NP_001 ----------------------------DLFNDLIACAFLVGAVVFAVRSRRSMNLHYLL
                                     100       110       120       

              190       200       210       220       230       240
pF1KE3 AVILIGAAGVFAFIDVCLQRNHFRGKKAKKHMLVPPPGKEKGPQQGKGPEPAKPPEPGKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVILIGAAGVFAFIDVCLQRNHFRGKKAKKHMLVPPPGKEKGPQQGKGPEPAKPPEPGKP
       130       140       150       160       170       180       

               
pF1KE3 PGPAKGKK
       ::::::::
NP_001 PGPAKGKK
       190     

>>NP_443725 (OMIM: 607884) CKLF-like MARVEL transmembran  (286 aa)
 initn: 204 init1: 152 opt: 223  Z-score: 181.9  bits: 41.4 E(85289): 0.0021
Smith-Waterman score: 231; 23.3% identity (55.3% similar) in 253 aa overlap (3-234:38-285)

                                           10        20            
pF1KE3                             MAPKAAKGAKPEPAPAPPPP--------GAKP
                                     ::: .. . . ::   :         .:  
NP_443 PESSEAPSGNLKQPETAAALASSGSVVSSVPKAQRNISAKTAPRKHPAVSIRSAQSAAAA
        10        20        30        40        50        60       

           30             40        50        60         70        
pF1KE3 EEDKKDGKEPSDK-----PQKAVQDHKEPSDKPQKAVQPKHEVGTR-RGCRRYRWELKDS
       . . ..:  :: :     : : .     :: . .. .  .  .  : .:  .  ....::
NP_443 RPQGSEGTAPSRKATTRPPPKPTLPPPTPSAHTESKLLNEMAIKERVEGRAKVPYKFRDS
        70        80        90       100       110       120       

       80        90       100       110       120       130        
pF1KE3 NKEFWLLGHAEIKIRSLGCLIAAMILLSSLTVHPILRLIITMEISFFSFFILLYSFAIHR
        :.: .   . .::  :. ...:.  .    ..  .  : ..:: .  ::::.: ...:.
NP_443 LKRFSFSPTGMLKILRLSLILGALACFIITQANESFITITSLEICIVVFFILIYVLTLHH
       130       140       150       160       170       180       

      140       150       160       170       180       190        
pF1KE3 YIPFILWPISDLFNDLIACAFLVGAVVFAVRSRRSMNLHYLLAVILIGAAGVF---AFID
        . .. ::. :: :..:. .::  ....:.. ..  .: :. . . . :. :    ::. 
NP_443 LLTYLHWPLLDLTNSIITAVFLSVVAILAMQEKKRRHLLYVGGSLCLTAVIVCCIDAFVV
       190       200       210       220       230       240       

         200          210       220       230        240        
pF1KE3 VCLQRNH---FRGKKAKKHMLVPPPGKEKGPQQGKGPE-PAKPPEPGKPPGPAKGKK
       .  .:..   : : ......    :.:.  :. :  :. : .:              
NP_443 TTKMRTNLKRFLGVEVERKL---SPAKDAYPETG--PDAPQRPA             
       250       260          270         280                   




248 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 00:33:33 2016 done: Mon Nov  7 00:33:34 2016
 Total Scan time:  8.150 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]