Result of FASTA (omim) for
pFN21AE3588
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3588, 786 aa
1>>>pF1KE3588 786 - 786 aa - 786 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6340+/-0.000359; mu= 8.8887+/- 0.023
mean_var=128.4971+/-25.363, 0's: 0 Z-trim(117.6): 41 B-trim: 33 in 1/55
Lambda= 0.113143
statistics sampled from 29670 (29711) to 29670 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.348), width: 16
Scan time: 10.970
The best scores are: opt bits E(85289)
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 5305 877.8 0
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 5271 872.2 0
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 3212 536.0 1.4e-151
XP_016879312 (OMIM: 600227) PREDICTED: cyclin-F is ( 446) 2447 411.1 5.1e-114
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 399 76.8 2.1e-13
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 399 76.8 2.1e-13
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 399 76.8 2.1e-13
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 399 76.8 2.1e-13
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 399 76.8 2.1e-13
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 399 76.9 2.3e-13
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 399 76.9 2.3e-13
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 377 73.3 2.6e-12
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 301 61.1 3.8e-08
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 301 61.1 3.8e-08
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 301 61.1 3.8e-08
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 301 61.1 3.9e-08
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 301 61.1 3.9e-08
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 301 61.1 3.9e-08
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 301 61.1 3.9e-08
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 286 58.4 7.6e-08
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 274 56.4 2.8e-07
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 236 50.2 1.6e-05
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 212 46.2 0.00023
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 206 45.3 0.00047
>>NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo sapi (786 aa)
initn: 5305 init1: 5305 opt: 5305 Z-score: 4685.4 bits: 877.8 E(85289): 0
Smith-Waterman score: 5305; 100.0% identity (100.0% similar) in 786 aa overlap (1-786:1-786)
10 20 30 40 50 60
pF1KE3 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN
730 740 750 760 770 780
pF1KE3 LGLVRL
::::::
NP_001 LGLVRL
>>XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F isofor (867 aa)
initn: 5271 init1: 5271 opt: 5271 Z-score: 4654.8 bits: 872.2 E(85289): 0
Smith-Waterman score: 5271; 99.7% identity (99.9% similar) in 784 aa overlap (3-786:84-867)
10 20 30
pF1KE3 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTI
: .:::::::::::::::::::::::::::
XP_016 TTQQSGHHGGRLPELRMPCAPGPKRRPTRASRAVVHCRCAKCFCYPTKRRIRRRPRNLTI
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE3 LSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFE
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE3 RAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLF
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE3 IRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEE
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE3 AAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQL
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE3 GLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLH
360 370 380 390 400 410
340 350 360 370 380 390
pF1KE3 LTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVR
420 430 440 450 460 470
400 410 420 430 440 450
pF1KE3 MMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARL
480 490 500 510 520 530
460 470 480 490 500 510
pF1KE3 AAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTA
540 550 560 570 580 590
520 530 540 550 560 570
pF1KE3 VKQRFEDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQRFEDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKR
600 610 620 630 640 650
580 590 600 610 620 630
pF1KE3 KRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAP
660 670 680 690 700 710
640 650 660 670 680 690
pF1KE3 SGILDVTVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGILDVTVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSRE
720 730 740 750 760 770
700 710 720 730 740 750
pF1KE3 PGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRP
780 790 800 810 820 830
760 770 780
pF1KE3 PSPPESSVPQQQVKRINLCIHSEEEDMNLGLVRL
::::::::::::::::::::::::::::::::::
XP_016 PSPPESSVPQQQVKRINLCIHSEEEDMNLGLVRL
840 850 860
>>NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Homo s (478 aa)
initn: 3212 init1: 3212 opt: 3212 Z-score: 2842.4 bits: 536.0 E(85289): 1.4e-151
Smith-Waterman score: 3212; 100.0% identity (100.0% similar) in 478 aa overlap (309-786:1-478)
280 290 300 310 320 330
pF1KE3 SSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECV
::::::::::::::::::::::::::::::
NP_001 MRYILIDWLVEVATMKDFTSLCLHLTVECV
10 20 30
340 350 360 370 380 390
pF1KE3 DRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIV
40 50 60 70 80 90
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALL
100 110 120 130 140 150
460 470 480 490 500 510
pF1KE3 LARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFE
160 170 180 190 200 210
520 530 540 550 560 570
pF1KE3 DKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSL
220 230 240 250 260 270
580 590 600 610 620 630
pF1KE3 QEDRGSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDRGSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDV
280 290 300 310 320 330
640 650 660 670 680 690
pF1KE3 TVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVT
340 350 360 370 380 390
700 710 720 730 740 750
pF1KE3 TSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPES
400 410 420 430 440 450
760 770 780
pF1KE3 SVPQQQVKRINLCIHSEEEDMNLGLVRL
::::::::::::::::::::::::::::
NP_001 SVPQQQVKRINLCIHSEEEDMNLGLVRL
460 470
>>XP_016879312 (OMIM: 600227) PREDICTED: cyclin-F isofor (446 aa)
initn: 2447 init1: 2447 opt: 2447 Z-score: 2168.0 bits: 411.1 E(85289): 5.1e-114
Smith-Waterman score: 2447; 99.4% identity (99.7% similar) in 363 aa overlap (3-365:84-446)
10 20 30
pF1KE3 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTI
: .:::::::::::::::::::::::::::
XP_016 TTQQSGHHGGRLPELRMPCAPGPKRRPTRASRAVVHCRCAKCFCYPTKRRIRRRPRNLTI
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE3 LSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFE
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE3 RAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLF
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE3 IRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEE
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE3 AAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQL
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE3 GLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLH
360 370 380 390 400 410
340 350 360 370 380 390
pF1KE3 LTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVR
:::::::::::::::::::::::::::::::::
XP_016 LTVECVDRYLRRRLVPRYRLQLLGIACMVICTR
420 430 440
400 410 420 430 440 450
pF1KE3 MMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARL
>>NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.7 bits: 76.8 E(85289): 2.1e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
NP_001 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
NP_001 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
NP_001 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
NP_001 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
NP_001 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
NP_001 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
NP_001 KASKYLCVSLMEPPAVLLLQ
410 420
>>NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.7 bits: 76.8 E(85289): 2.1e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
NP_001 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
NP_001 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
NP_001 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
NP_001 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
NP_001 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
NP_001 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
NP_001 KASKYLCVSLMEPPAVLLLQ
410 420
>>XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.7 bits: 76.8 E(85289): 2.1e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
XP_011 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
XP_011 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
XP_011 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
XP_011 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
XP_011 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
XP_011 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
XP_011 KASKYLCVSLMEPPAVLLLQ
410 420
>>XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.7 bits: 76.8 E(85289): 2.1e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
XP_011 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
XP_011 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
XP_011 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
XP_011 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
XP_011 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
XP_011 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
XP_011 KASKYLCVSLMEPPAVLLLQ
410 420
>>XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.7 bits: 76.8 E(85289): 2.1e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
XP_011 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
XP_011 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
XP_011 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
XP_011 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
XP_011 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
XP_011 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
XP_011 KASKYLCVSLMEPPAVLLLQ
410 420
>>NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [Homo (464 aa)
initn: 306 init1: 306 opt: 399 Z-score: 361.0 bits: 76.9 E(85289): 2.3e-13
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:127-456)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
NP_001 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
NP_001 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
NP_001 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
220 230 240 250 260 270
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
NP_001 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
NP_001 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
NP_001 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
400 410 420 430 440
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
NP_001 KASKYLCVSLMEPPAVLLLQ
450 460
786 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:42:12 2016 done: Mon Nov 7 01:42:14 2016
Total Scan time: 10.970 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]