Result of FASTA (omim) for
pFN21AE3538
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3538, 819 aa
1>>>pF1KE3538 819 - 819 aa - 819 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.9768+/-0.00055; mu= -16.9663+/- 0.034
mean_var=783.4561+/-165.626, 0's: 0 Z-trim(122.4): 1441 B-trim: 0 in 0/55
Lambda= 0.045821
statistics sampled from 38577 (40491) to 38577 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.475), width: 16
Scan time: 13.690
The best scores are: opt bits E(85289)
NP_872299 (OMIM: 612147) myosin light chain kinase ( 819) 5536 382.1 5.2e-105
XP_006721397 (OMIM: 612147) PREDICTED: myosin ligh ( 478) 3223 229.0 4e-59
NP_001295230 (OMIM: 612147) myosin light chain kin ( 478) 3223 229.0 4e-59
NP_149109 (OMIM: 192600,606566) myosin light chain ( 596) 1504 115.4 7.4e-25
XP_016861959 (OMIM: 600922,613780) PREDICTED: myos ( 713) 1056 85.9 6.8e-16
XP_016861960 (OMIM: 600922,613780) PREDICTED: myos ( 714) 1056 85.9 6.8e-16
XP_016861958 (OMIM: 600922,613780) PREDICTED: myos ( 991) 1056 86.1 8.4e-16
NP_001308238 (OMIM: 600922,613780) myosin light ch (1738) 1056 86.4 1.2e-15
NP_444254 (OMIM: 600922,613780) myosin light chain (1845) 1056 86.4 1.2e-15
XP_011511162 (OMIM: 600922,613780) PREDICTED: myos (1913) 1056 86.4 1.3e-15
NP_444253 (OMIM: 600922,613780) myosin light chain (1914) 1056 86.4 1.3e-15
XP_016877533 (OMIM: 616567) PREDICTED: death-assoc ( 350) 829 70.5 1.4e-11
NP_055141 (OMIM: 616567) death-associated protein ( 370) 829 70.6 1.5e-11
XP_011519716 (OMIM: 616567) PREDICTED: death-assoc ( 380) 829 70.6 1.5e-11
XP_011519715 (OMIM: 616567) PREDICTED: death-assoc ( 389) 829 70.6 1.5e-11
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 809 69.4 4.2e-11
NP_001339 (OMIM: 603289) death-associated protein ( 454) 809 69.4 4.2e-11
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 817 70.2 4.3e-11
NP_004929 (OMIM: 600831) death-associated protein (1430) 817 70.5 6e-11
NP_001275659 (OMIM: 600831) death-associated prote (1430) 817 70.5 6e-11
NP_001275660 (OMIM: 600831) death-associated prote (1430) 817 70.5 6e-11
NP_001275658 (OMIM: 600831) death-associated prote (1430) 817 70.5 6e-11
XP_011511163 (OMIM: 600922,613780) PREDICTED: myos (1846) 813 70.4 8.6e-11
XP_011519718 (OMIM: 616567) PREDICTED: death-assoc ( 488) 787 67.9 1.2e-10
XP_011519717 (OMIM: 616567) PREDICTED: death-assoc ( 359) 779 67.3 1.4e-10
XP_011519719 (OMIM: 616567) PREDICTED: death-assoc ( 316) 744 64.9 6.5e-10
XP_016877535 (OMIM: 616567) PREDICTED: death-assoc ( 316) 744 64.9 6.5e-10
XP_016877534 (OMIM: 616567) PREDICTED: death-assoc ( 316) 744 64.9 6.5e-10
NP_004751 (OMIM: 604726) serine/threonine-protein ( 414) 726 63.8 1.8e-09
NP_444256 (OMIM: 600922,613780) myosin light chain (1794) 745 65.8 1.9e-09
NP_444255 (OMIM: 600922,613780) myosin light chain (1863) 745 65.9 1.9e-09
NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 782 69.7 2e-09
XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 782 69.7 2e-09
NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 782 69.7 2e-09
NP_597681 (OMIM: 188840,600334,603689,604145,60880 (27118) 782 69.7 2e-09
XP_016860311 (OMIM: 188840,600334,603689,604145,60 (33101) 782 69.8 2.2e-09
NP_596869 (OMIM: 188840,600334,603689,604145,60880 (33423) 782 69.8 2.3e-09
XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 782 69.8 2.3e-09
XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 782 69.8 2.3e-09
NP_001243779 (OMIM: 188840,600334,603689,604145,60 (34350) 782 69.8 2.3e-09
XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 782 69.8 2.4e-09
NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 782 69.8 2.4e-09
XP_011510471 (OMIM: 604727) PREDICTED: serine/thre ( 372) 654 59.0 4.5e-08
XP_011510470 (OMIM: 604727) PREDICTED: serine/thre ( 372) 654 59.0 4.5e-08
XP_011510472 (OMIM: 604727) PREDICTED: serine/thre ( 372) 654 59.0 4.5e-08
NP_004217 (OMIM: 604727) serine/threonine-protein ( 372) 654 59.0 4.5e-08
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 647 58.5 6e-08
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 647 58.5 6e-08
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 647 58.5 6.1e-08
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 647 58.6 6.3e-08
>>NP_872299 (OMIM: 612147) myosin light chain kinase 3 i (819 aa)
initn: 5536 init1: 5536 opt: 5536 Z-score: 2006.2 bits: 382.1 E(85289): 5.2e-105
Smith-Waterman score: 5536; 99.9% identity (100.0% similar) in 819 aa overlap (1-819:1-819)
10 20 30 40 50 60
pF1KE3 MSGTSKESLGHGGLPGLGKTCLTTMDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MSGTSKESLGHGGLPGLGKTCLTTMDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_872 VDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QSDAREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 QSDAREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 GTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 GAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 GAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 EAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 LAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 RRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAET
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 MNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRS
730 740 750 760 770 780
790 800 810
pF1KE3 KTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:::::::::::::::::::::::::::::::::::::::
NP_872 KTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
790 800 810
>>XP_006721397 (OMIM: 612147) PREDICTED: myosin light ch (478 aa)
initn: 3223 init1: 3223 opt: 3223 Z-score: 1182.5 bits: 229.0 E(85289): 4e-59
Smith-Waterman score: 3223; 100.0% identity (100.0% similar) in 478 aa overlap (342-819:1-478)
320 330 340 350 360 370
pF1KE3 CPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPG
::::::::::::::::::::::::::::::
XP_006 MDTPGEMLMTGRGSLGPTLTTEAPAAAQPG
10 20 30
380 390 400 410 420 430
pF1KE3 KQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLA
40 50 60 70 80 90
440 450 460 470 480 490
pF1KE3 RSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSP
100 110 120 130 140 150
500 510 520 530 540 550
pF1KE3 APPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSA
160 170 180 190 200 210
560 570 580 590 600 610
pF1KE3 KDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTEL
220 230 240 250 260 270
620 630 640 650 660 670
pF1KE3 DVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKV
280 290 300 310 320 330
680 690 700 710 720 730
pF1KE3 NFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDF
340 350 360 370 380 390
740 750 760 770 780 790
pF1KE3 DADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQ
400 410 420 430 440 450
800 810
pF1KE3 KYIAQRKWKKHFYVVTAANRLRKFPTSP
::::::::::::::::::::::::::::
XP_006 KYIAQRKWKKHFYVVTAANRLRKFPTSP
460 470
>>NP_001295230 (OMIM: 612147) myosin light chain kinase (478 aa)
initn: 3223 init1: 3223 opt: 3223 Z-score: 1182.5 bits: 229.0 E(85289): 4e-59
Smith-Waterman score: 3223; 100.0% identity (100.0% similar) in 478 aa overlap (342-819:1-478)
320 330 340 350 360 370
pF1KE3 CPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPG
::::::::::::::::::::::::::::::
NP_001 MDTPGEMLMTGRGSLGPTLTTEAPAAAQPG
10 20 30
380 390 400 410 420 430
pF1KE3 KQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLA
40 50 60 70 80 90
440 450 460 470 480 490
pF1KE3 RSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSP
100 110 120 130 140 150
500 510 520 530 540 550
pF1KE3 APPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSA
160 170 180 190 200 210
560 570 580 590 600 610
pF1KE3 KDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTEL
220 230 240 250 260 270
620 630 640 650 660 670
pF1KE3 DVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKV
280 290 300 310 320 330
680 690 700 710 720 730
pF1KE3 NFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDF
340 350 360 370 380 390
740 750 760 770 780 790
pF1KE3 DADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQ
400 410 420 430 440 450
800 810
pF1KE3 KYIAQRKWKKHFYVVTAANRLRKFPTSP
::::::::::::::::::::::::::::
NP_001 KYIAQRKWKKHFYVVTAANRLRKFPTSP
460 470
>>NP_149109 (OMIM: 192600,606566) myosin light chain kin (596 aa)
initn: 1534 init1: 1446 opt: 1504 Z-score: 567.3 bits: 115.4 E(85289): 7.4e-25
Smith-Waterman score: 1537; 45.5% identity (66.7% similar) in 595 aa overlap (271-818:10-588)
250 260 270 280 290 300
pF1KE3 PLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEE
... .:: . :: .: .. :: :
NP_149 MATENGAVELGIQNPSTDKAP---KGPTGERP----LAA
10 20 30
310 320 330 340 350
pF1KE3 GTRLTPGP-GPQ-CPGPPGLP--AQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSL
: ::: :. : :: : :.: :...: : . : : :. ::.
NP_149 GK--DPGPPDPKKAPDPPTLKKDAKAPASEKGDGTLAQPSTSSQGPKGEGD-----RGG-
40 50 60 70 80
360 370 380 390 400
pF1KE3 GPTLTTEAPAAAQPGKQGPPGTG----------RCLQAPGTEP--GEQTPEG---ARELS
::. . .: :: : . . : :. : :: .: :... :: ::. :
NP_149 GPAEGSAGPPAALPQQTATPETSVKKPKAEQGASGSQDPG-KPRVGKKAAEGQAAARRGS
90 100 110 120 130 140
410 420 430 440
pF1KE3 P--LQESSSPGGVKAEEEQRAGAEPG----------------TRPSLARSDDNDHEVGAL
: :. : :. ... :. : :. : : :..... . ..
NP_149 PAFLHSPSCPAIISSSEKLLAKKPPSEASELTFEGVPMTHSPTDPRPAKAEEGKNILAES
150 160 170 180 190 200
450 460 470 480 490
pF1KE3 GLQQG-KSPG-AGNPEPEQDCAARAPVRAEAVRRMPPGA--------EAGSVVLDDSPAP
. : :.:: ::. . . : . .: .. : : .::: : :
NP_149 QKEVGEKTPGQAGQAKMQGDTSRGIEFQAVPSEKSEVGQALCLTAREEDCFQILDDCPPP
210 220 230 240 250 260
500 510 520 530 540 550
pF1KE3 PAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKD
:::: ::.: .. ..:. . . ..:.::::.:: : : ::.::: ::::.:: .. ::
NP_149 PAPFPHRMVELRTGNVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKD
270 280 290 300 310 320
560 570 580 590 600 610
pF1KE3 REDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDV
.: : ::..::::.: :::::: :.:. : .: :::..:::::.::.:: :::::.:.
NP_149 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT
330 340 350 360 370 380
620 630 640 650 660 670
pF1KE3 VLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNF
..:.::::.:. ..:. .:::::::::::::: ::: .:::::::::::.: :::::::
NP_149 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNF
390 400 410 420 430 440
680 690 700 710 720 730
pF1KE3 GTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDA
::::::.::::::. .: :::::.::::::::::::::::. :.::.: ... .: ::
NP_149 GTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDE
450 460 470 480 490 500
740 750 760 770 780 790
pF1KE3 DTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQKY
.:::..:.::::::: :.::.. ::.:.::: : ::::: ::.: . :::::.::.::
NP_149 ETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKY
510 520 530 540 550 560
800 810
pF1KE3 IAQRKWKKHFYVVTAANRLRKFPTSP
. .:.:::.: .:.::::..:. .:
NP_149 LMKRRWKKNFIAVSAANRFKKISSSGALMALGV
570 580 590
>>XP_016861959 (OMIM: 600922,613780) PREDICTED: myosin l (713 aa)
initn: 1061 init1: 965 opt: 1056 Z-score: 406.3 bits: 85.9 E(85289): 6.8e-16
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:211-558)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
XP_016 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
190 200 210 220 230
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
XP_016 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
240 250 260 270 280 290
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
XP_016 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
300 310 320 330 340 350
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
XP_016 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
360 370 380 390 400 410
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
XP_016 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
420 430 440 450 460 470
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
XP_016 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
480 490 500 510 520 530
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
XP_016 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
540 550 560 570 580
XP_016 KLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD
590 600 610 620 630 640
>>XP_016861960 (OMIM: 600922,613780) PREDICTED: myosin l (714 aa)
initn: 1061 init1: 965 opt: 1056 Z-score: 406.3 bits: 85.9 E(85289): 6.8e-16
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:211-558)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
XP_016 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
190 200 210 220 230
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
XP_016 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
240 250 260 270 280 290
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
XP_016 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
300 310 320 330 340 350
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
XP_016 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
360 370 380 390 400 410
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
XP_016 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
420 430 440 450 460 470
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
XP_016 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
480 490 500 510 520 530
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
XP_016 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
540 550 560 570 580
XP_016 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK
590 600 610 620 630 640
>>XP_016861958 (OMIM: 600922,613780) PREDICTED: myosin l (991 aa)
initn: 1061 init1: 965 opt: 1056 Z-score: 404.7 bits: 86.1 E(85289): 8.4e-16
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:489-836)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
XP_016 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
460 470 480 490 500 510
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
XP_016 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
520 530 540 550 560
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
XP_016 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
570 580 590 600 610 620
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
XP_016 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
630 640 650 660 670 680
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
XP_016 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
690 700 710 720 730 740
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
XP_016 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
750 760 770 780 790 800
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
XP_016 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
810 820 830 840 850 860
XP_016 KLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD
870 880 890 900 910 920
>>NP_001308238 (OMIM: 600922,613780) myosin light chain (1738 aa)
initn: 1026 init1: 965 opt: 1056 Z-score: 401.9 bits: 86.4 E(85289): 1.2e-15
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:1235-1582)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
NP_001 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
1210 1220 1230 1240 1250
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
NP_001 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
1260 1270 1280 1290 1300 1310
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
NP_001 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
1320 1330 1340 1350 1360 1370
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
NP_001 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
1380 1390 1400 1410 1420 1430
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
NP_001 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
1440 1450 1460 1470 1480 1490
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
NP_001 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
1500 1510 1520 1530 1540 1550
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
NP_001 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
1560 1570 1580 1590 1600
NP_001 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK
1610 1620 1630 1640 1650 1660
>>NP_444254 (OMIM: 600922,613780) myosin light chain kin (1845 aa)
initn: 1026 init1: 965 opt: 1056 Z-score: 401.6 bits: 86.4 E(85289): 1.2e-15
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:1342-1689)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
NP_444 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
1320 1330 1340 1350 1360
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
NP_444 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
1370 1380 1390 1400 1410 1420
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
NP_444 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
1430 1440 1450 1460 1470 1480
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
NP_444 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
1490 1500 1510 1520 1530 1540
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
NP_444 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
1550 1560 1570 1580 1590 1600
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
NP_444 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
1610 1620 1630 1640 1650 1660
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
NP_444 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
1670 1680 1690 1700 1710
NP_444 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK
1720 1730 1740 1750 1760 1770
>>XP_011511162 (OMIM: 600922,613780) PREDICTED: myosin l (1913 aa)
initn: 1026 init1: 965 opt: 1056 Z-score: 401.4 bits: 86.4 E(85289): 1.3e-15
Smith-Waterman score: 1056; 47.3% identity (73.1% similar) in 364 aa overlap (454-812:1411-1758)
430 440 450 460 470 480
pF1KE3 PGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAG
:. :: :. . .: . : .
XP_011 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES------ELTTVGEKPEEPKDE
1390 1400 1410 1420 1430
490 500 510 520 530 540
pF1KE3 SVVLDDSPAPPAPFEHRVVSVK-ETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLA
: ::. : ..:.:... : ..: :.. .: ::.:.:::: : .::.: :
XP_011 VEVSDDDEKEPE-VDYRTVTINTEQKVSDFYDI--EERLGSGKFGQVFRLVEKKTRKVWA
1440 1450 1460 1470 1480 1490
550 560 570 580 590 600
pF1KE3 AKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT
.:..:. :::..:....::.::: : : .:.: :::: : . ..:.: :.:::::.::
XP_011 GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERII
1500 1510 1520 1530 1540 1550
610 620 630 640 650 660
pF1KE3 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARR
:: ..::: . . . ::: :::.:.:.. :.:::::::::.:::.:: .::.::::::::
XP_011 DEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
1560 1570 1580 1590 1600 1610
670 680 690 700 710 720
pF1KE3 YKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMN
. .::: ::::::.::::.::: ... :::::.::: :.:.::::::.:..: ::.
XP_011 LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
1620 1630 1640 1650 1660 1670
730 740 750 760 770
pF1KE3 FIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL----NNLPAKAS
... .:::: ..:. .:..::::.: :: :. . :.. ::::.: :: .:. :: .
XP_011 NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAK-K
1680 1690 1700 1710 1720 1730
780 790 800 810
pF1KE3 RSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
:: :.: ::.:.:::.: .: : .::
XP_011 LSKDRMK------KYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAE
1740 1750 1760 1770 1780
XP_011 KLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD
1790 1800 1810 1820 1830 1840
819 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:29:46 2016 done: Mon Nov 7 16:29:48 2016
Total Scan time: 13.690 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]