Result of FASTA (omim) for
pFN21AE3527
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3527, 429 aa
1>>>pF1KE3527 429 - 429 aa - 429 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2546+/-0.000344; mu= 24.4307+/- 0.022
mean_var=105.3194+/-24.958, 0's: 0 Z-trim(115.8): 165 B-trim: 1606 in 1/54
Lambda= 0.124974
statistics sampled from 26311 (26567) to 26311 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.311), width: 16
Scan time: 8.500
The best scores are: opt bits E(85289)
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 2475 457.1 3.4e-128
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 2467 455.7 9.9e-128
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 2422 447.6 2.6e-125
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 2422 447.6 2.6e-125
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 2422 447.6 2.6e-125
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 2422 447.6 2.7e-125
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 2414 446.1 6.9e-125
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 2408 445.0 1.5e-124
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 457 93.1 1e-18
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 457 93.1 1e-18
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 457 93.2 1.1e-18
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 406 84.1 7.1e-16
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 401 83.1 1.2e-15
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 401 83.1 1.2e-15
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 401 83.2 1.3e-15
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 376 78.6 2.8e-14
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 376 78.6 2.8e-14
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 372 78.0 4.8e-14
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 368 77.0 6.4e-14
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 369 77.3 6.6e-14
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 365 76.6 1.1e-13
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 355 74.7 3.6e-13
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 355 74.8 3.7e-13
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 355 74.8 3.7e-13
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 355 74.8 3.8e-13
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 355 75.0 4.6e-13
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 310 66.6 9.7e-11
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 230 52.5 2.8e-06
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 230 52.6 2.9e-06
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 213 49.4 2.3e-05
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 213 49.5 2.5e-05
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389) 206 48.0 5e-05
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389) 206 48.0 5e-05
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 199 46.8 0.00012
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 180 43.4 0.0013
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 165 40.5 0.0076
XP_011535421 (OMIM: 275200,603372,603373,609152) P ( 671) 168 41.5 0.0077
XP_005268094 (OMIM: 275200,603372,603373,609152) P ( 764) 168 41.6 0.0082
NP_000360 (OMIM: 275200,603372,603373,609152) thyr ( 764) 168 41.6 0.0082
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 165 40.7 0.0088
>>NP_942009 (OMIM: 176806) prostaglandin E2 receptor EP3 (374 aa)
initn: 2466 init1: 2466 opt: 2475 Z-score: 2422.4 bits: 457.1 E(85289): 3.4e-128
Smith-Waterman score: 2475; 99.5% identity (99.5% similar) in 372 aa overlap (1-370:1-372)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 RKRRLREQ--FWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASW
:::::::: ::
NP_942 RKRRLREQEEFWGN
370
>>NP_942011 (OMIM: 176806) prostaglandin E2 receptor EP3 (418 aa)
initn: 2467 init1: 2467 opt: 2467 Z-score: 2414.2 bits: 455.7 E(85289): 9.9e-128
Smith-Waterman score: 2467; 99.7% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
::::::::.
NP_942 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
370 380 390 400 410
>>NP_942007 (OMIM: 176806) prostaglandin E2 receptor EP3 (390 aa)
initn: 2416 init1: 2416 opt: 2422 Z-score: 2370.6 bits: 447.6 E(85289): 2.6e-125
Smith-Waterman score: 2423; 92.2% identity (94.5% similar) in 400 aa overlap (1-400:1-386)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
: . . . .:.. :: :: : ..:::
NP_942 R---YHTNNYASSSTSLPCQ--------CSST---LMWSDHLER
370 380 390
pF1KE3 VILLPQPPK
>>NP_001119516 (OMIM: 176806) prostaglandin E2 receptor (390 aa)
initn: 2416 init1: 2416 opt: 2422 Z-score: 2370.6 bits: 447.6 E(85289): 2.6e-125
Smith-Waterman score: 2423; 92.2% identity (94.5% similar) in 400 aa overlap (1-400:1-386)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
: . . . .:.. :: :: : ..:::
NP_001 R---YHTNNYASSSTSLPCQ--------CSST---LMWSDHLER
370 380 390
pF1KE3 VILLPQPPK
>>NP_942012 (OMIM: 176806) prostaglandin E2 receptor EP3 (390 aa)
initn: 2416 init1: 2416 opt: 2422 Z-score: 2370.6 bits: 447.6 E(85289): 2.6e-125
Smith-Waterman score: 2423; 92.2% identity (94.5% similar) in 400 aa overlap (1-400:1-386)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
: . . . .:.. :: :: : ..:::
NP_942 R---YHTNNYASSSTSLPCQ--------CSST---LMWSDHLER
370 380 390
pF1KE3 VILLPQPPK
>>XP_011540112 (OMIM: 176806) PREDICTED: prostaglandin E (410 aa)
initn: 2416 init1: 2416 opt: 2422 Z-score: 2370.4 bits: 447.6 E(85289): 2.7e-125
Smith-Waterman score: 2423; 92.2% identity (94.5% similar) in 400 aa overlap (1-400:1-386)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
: . . . .:.. :: :: : ..:::
XP_011 R---YHTNNYASSSTSLPCQ--------CSST---LMWSDHLERRNFGEIKTCLSARITS
370 380 390 400
pF1KE3 VILLPQPPK
XP_011 LEAP
410
>>NP_942010 (OMIM: 176806) prostaglandin E2 receptor EP3 (365 aa)
initn: 2407 init1: 2407 opt: 2414 Z-score: 2363.1 bits: 446.1 E(85289): 6.9e-125
Smith-Waterman score: 2414; 97.8% identity (98.1% similar) in 370 aa overlap (1-370:1-363)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQ-
310 320 330 340 350
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
:.::
NP_942 ------EEFWGN
360
>>NP_942008 (OMIM: 176806) prostaglandin E2 receptor EP3 (388 aa)
initn: 2408 init1: 2408 opt: 2408 Z-score: 2357.0 bits: 445.0 E(85289): 1.5e-124
Smith-Waterman score: 2408; 99.7% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KE3 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RKRRLREQFWRPASSGSGCQQIRCLMESCSLTQTGVQWSDFRSLQPSPPPLTAIFASWVQ
NP_942 ANAVSSCSNDGQKGQPISLSNEIIQTEA
370 380
>>XP_016857362 (OMIM: 600563) PREDICTED: prostaglandin F (291 aa)
initn: 530 init1: 386 opt: 457 Z-score: 457.1 bits: 93.1 E(85289): 1e-18
Smith-Waterman score: 541; 34.9% identity (66.9% similar) in 272 aa overlap (50-321:28-284)
20 30 40 50 60 70
pF1KE3 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
.:: : . .. .:...:.::. .. ..:.:
XP_016 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
10 20 30 40 50
80 90 100 110 120 130
pF1KE3 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
XP_016 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE3 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
XP_016 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE3 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
XP_016 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
180 190 200 210 220
260 270 280 290 300 310
pF1KE3 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHT
. : ::. : : .:::..:::: .::::.: . ..:.: :. :..
XP_016 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGY--RIILNGK--EKYKVYE
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE3 EKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQFWRPASSGSGC
:.
XP_016 EQSDFLHRK
290
>>NP_001034674 (OMIM: 600563) prostaglandin F2-alpha rec (297 aa)
initn: 530 init1: 386 opt: 457 Z-score: 457.0 bits: 93.1 E(85289): 1e-18
Smith-Waterman score: 541; 34.9% identity (66.9% similar) in 272 aa overlap (50-321:28-284)
20 30 40 50 60 70
pF1KE3 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
.:: : . .. .:...:.::. .. ..:.:
NP_001 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
10 20 30 40 50
80 90 100 110 120 130
pF1KE3 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
NP_001 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE3 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
NP_001 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE3 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
NP_001 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
180 190 200 210 220
260 270 280 290 300 310
pF1KE3 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHT
. : ::. : : .:::..:::: .::::.: . ..:.: :. :..
NP_001 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGY--RIILNGK--EKYKVYE
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE3 EKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQFWRPASSGSGC
:.
NP_001 EQSDFLHRLQWPTLE
290
429 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:42:47 2016 done: Fri Nov 4 17:42:48 2016
Total Scan time: 8.500 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]