Result of FASTA (ccds) for
pFN21AE3521
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3521, 455 aa
1>>>pF1KE3521 455 - 455 aa - 455 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4459+/-0.000976; mu= -4.9142+/- 0.059
mean_var=306.4852+/-61.441, 0's: 0 Z-trim(115.5): 53 B-trim: 0 in 0/50
Lambda= 0.073260
statistics sampled from 16022 (16072) to 16022 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.494), width: 16
Scan time: 3.670
The best scores are: opt bits E(32554)
CCDS81504.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 455) 2977 327.9 1.3e-89
CCDS55729.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 459) 2959 326.0 4.9e-89
CCDS7576.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 596) 2959 326.1 6e-89
CCDS73197.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 579) 2835 313.0 5.2e-85
CCDS53577.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 602) 1992 223.9 3.5e-58
CCDS73196.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 476) 1881 212.1 1e-54
CCDS73198.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 408) 1780 201.4 1.5e-51
CCDS53578.1 TCF7L2 gene_id:6934|Hs108|chr10 ( 489) 1767 200.1 4.3e-51
CCDS1971.1 TCF7L1 gene_id:83439|Hs108|chr2 ( 588) 1521 174.1 3.4e-43
CCDS3679.1 LEF1 gene_id:51176|Hs108|chr4 ( 399) 1291 149.7 5.2e-36
CCDS54791.1 LEF1 gene_id:51176|Hs108|chr4 ( 303) 788 96.4 4.2e-20
CCDS47123.1 LEF1 gene_id:51176|Hs108|chr4 ( 371) 788 96.5 4.9e-20
CCDS47122.1 LEF1 gene_id:51176|Hs108|chr4 ( 386) 788 96.5 5.1e-20
CCDS47263.2 TCF7 gene_id:6932|Hs108|chr5 ( 269) 705 87.6 1.7e-17
CCDS43362.1 TCF7 gene_id:6932|Hs108|chr5 ( 268) 701 87.2 2.3e-17
CCDS4170.1 TCF7 gene_id:6932|Hs108|chr5 ( 269) 699 87.0 2.6e-17
CCDS4169.1 TCF7 gene_id:6932|Hs108|chr5 ( 384) 699 87.1 3.4e-17
>>CCDS81504.1 TCF7L2 gene_id:6934|Hs108|chr10 (455 aa)
initn: 2977 init1: 2977 opt: 2977 Z-score: 1722.3 bits: 327.9 E(32554): 1.3e-89
Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWQGQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 WHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 WHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLN
370 380 390 400 410 420
430 440 450
pF1KE3 PCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
:::::::::
CCDS81 PCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCSL
430 440 450
>>CCDS55729.1 TCF7L2 gene_id:6934|Hs108|chr10 (459 aa)
initn: 2963 init1: 1646 opt: 2959 Z-score: 1711.9 bits: 326.0 E(32554): 4.9e-89
Smith-Waterman score: 2959; 99.1% identity (99.1% similar) in 433 aa overlap (1-429:1-433)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
370 380 390 400 410 420
420 430 440 450
pF1KE3 CFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
:::::::::::::
CCDS55 CFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCSL
430 440 450
>>CCDS7576.1 TCF7L2 gene_id:6934|Hs108|chr10 (596 aa)
initn: 2963 init1: 1646 opt: 2959 Z-score: 1710.4 bits: 326.1 E(32554): 6e-89
Smith-Waterman score: 2959; 99.1% identity (99.1% similar) in 433 aa overlap (1-429:1-433)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
370 380 390 400 410 420
420 430 440 450
pF1KE3 CFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
:::::::::::::
CCDS75 CFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSD
430 440 450 460 470 480
>>CCDS73197.1 TCF7L2 gene_id:6934|Hs108|chr10 (579 aa)
initn: 2887 init1: 1646 opt: 2835 Z-score: 1639.7 bits: 313.0 E(32554): 5.2e-85
Smith-Waterman score: 2835; 98.6% identity (98.8% similar) in 419 aa overlap (1-415:1-419)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::. :
CCDS73 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNDLSA
370 380 390 400 410 420
420 430 440 450
pF1KE3 CFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
CCDS73 PKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSP
430 440 450 460 470 480
>>CCDS53577.1 TCF7L2 gene_id:6934|Hs108|chr10 (602 aa)
initn: 2110 init1: 1205 opt: 1992 Z-score: 1158.0 bits: 223.9 E(32554): 3.5e-58
Smith-Waterman score: 2777; 93.6% identity (93.9% similar) in 440 aa overlap (1-413:1-440)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150
pF1KE3 LSPTART-----------------------YLQMKWPLLDVQAGSLQSRQALKDARSPSP
::::::: ::::::::::::::::::::::::::::::
CCDS53 LSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 PYYPLSPGTVGQIPHPLGW----QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
CCDS53 PYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 DNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQME
:::::::::::::::::::.
CCDS53 DNYGKKKKRKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGSCL
430 440 450 460 470 480
>>CCDS73196.1 TCF7L2 gene_id:6934|Hs108|chr10 (476 aa)
initn: 2775 init1: 1646 opt: 1881 Z-score: 1096.0 bits: 212.1 E(32554): 1e-54
Smith-Waterman score: 2939; 97.9% identity (97.9% similar) in 438 aa overlap (1-429:1-438)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QGQPVYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHTLHTTGIPHPAIVTPT
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::
CCDS73 QGQPVYPITTGGFRHPYPTALTVNASMSSFLSSRFPPHMVPPHHTLHTTGIPHPAIVTPT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 VKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 AINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGET
370 380 390 400 410 420
420 430 440 450
pF1KE3 NEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
::::::::::::::::::
CCDS73 NEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRCKYSKEVSGTVRA
430 440 450 460 470
>>CCDS73198.1 TCF7L2 gene_id:6934|Hs108|chr10 (408 aa)
initn: 2208 init1: 1203 opt: 1780 Z-score: 1039.2 bits: 201.4 E(32554): 1.5e-51
Smith-Waterman score: 2643; 88.0% identity (88.0% similar) in 459 aa overlap (1-455:1-408)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPL
::::::: :::::::::::::::::::
CCDS73 LSPTART----------------------------------SNKVPVVQHPHHVHPLTPL
130 140
190 200 210 220 230
pF1KE3 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQ
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE3 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQES
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE3 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE3 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN----
330 340 350 360 370 380
420 430 440 450
pF1KE3 CFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
::::::::::::::::::::::::::
CCDS73 -------------GEKKSAFATYKVKAAASAHPLQMEAY
390 400
>>CCDS53578.1 TCF7L2 gene_id:6934|Hs108|chr10 (489 aa)
initn: 2441 init1: 1203 opt: 1767 Z-score: 1030.7 bits: 200.1 E(32554): 4.3e-51
Smith-Waterman score: 2712; 86.0% identity (86.0% similar) in 487 aa overlap (20-455:20-489)
10 20 30 40 50 60
pF1KE3 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
:::::::::::::::::::::::::::::::::::::::::
CCDS53 MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
70 80 90 100 110 120
130 140 150 160
pF1KE3 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVS------------------
::::::::::::::::::::::::::::::::::::::::::
CCDS53 LSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPLPCCTQGHDCQHFYPPS
130 140 150 160 170 180
170 180 190
pF1KE3 -----------------------------NKVPVVQHPHHVHPLTPLITYSNEHFTPGNP
:::::::::::::::::::::::::::::::
CCDS53 DFTVSTQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLTPLITYSNEHFTPGNP
190 200 210 220 230 240
200 210 220 230 240
pF1KE3 PPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----QGQPVYPITTGGF
::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
CCDS53 PPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGF
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE3 RHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 RHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKH
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE3 QDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 QDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQ
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE3 AKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPIT
:::::::::::::::::::::::::::::::::::::::::::
CCDS53 AKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETN-----------------
430 440 450 460
430 440 450
pF1KE3 GEKKSAFATYKVKAAASAHPLQMEAY
::::::::::::::::::::::::::
CCDS53 GEKKSAFATYKVKAAASAHPLQMEAY
470 480
>>CCDS1971.1 TCF7L1 gene_id:83439|Hs108|chr2 (588 aa)
initn: 1611 init1: 676 opt: 1521 Z-score: 889.1 bits: 174.1 E(32554): 3.4e-43
Smith-Waterman score: 1988; 68.9% identity (82.2% similar) in 444 aa overlap (7-427:27-461)
10 20 30
pF1KE3 MPQLNGGGGDDLGANDELISFKDEG-EQEEKSSENSSAER
::::::::::::: :.::: :..: ::...::.:
CCDS19 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 DLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPP
:: .:::::::::: ::.::::::::::: : ..:. : :. . :. . ::...:::::
CCDS19 DLDEVKSSLVNESE-NQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPP
70 80 90 100 110
100 110 120 130 140 150
pF1KE3 YPGYPFIMIPDLTSPYLPNGSLSPT-ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA
::::::.:::::.:::: :: ::: :::::::::::::: : ..::.::::::
CCDS19 YPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDV-----PSSATVKDTRSPSPA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP
:. ::::::::::::.:::::::::::.::.::.:: :: ..:::::::::::: ..::
CCDS19 HL-SNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSP
180 190 200 210 220 230
220 230 240 250 260
pF1KE3 YYPLSPGTVGQIPHPLGW----QGQPVYPITTGGFRHPYPTALTVNASMS-----RFPPH
:::::::.:::::::::: ::::.: . :::::::: ::..::::: :: ::
CCDS19 YYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPH
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE3 MVPPHHT-LHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLN
:: : : : :.::::::::.: :::: . ... : : . :.::.::::.:::::
CCDS19 MVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLN
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE3 AFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYP
:::::::::::::::::::::::::::::::.:: :::::::::::::::::::: ::::
CCDS19 AFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYP
360 370 380 390 400 410
390 400 410 420 430
pF1KE3 GWSARDNYGKKKKRKRDKQPGETN-----EHSECFL-----NPCLS-LPPITGEKKSAFA
:::::::::::::::.:: ..:. ...: : .::.. :::
CCDS19 TWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASS
420 430 440 450 460 470
440 450
pF1KE3 TYKVKAAASAHPLQMEAY
CCDS19 HGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASS
480 490 500 510 520 530
>>CCDS3679.1 LEF1 gene_id:51176|Hs108|chr4 (399 aa)
initn: 1582 init1: 863 opt: 1291 Z-score: 760.0 bits: 149.7 E(32554): 5.2e-36
Smith-Waterman score: 1549; 60.3% identity (74.4% similar) in 418 aa overlap (1-406:1-382)
10 20 30 40 50
pF1KE3 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEKS-SENSSAER--DLADVKSSLVNE
::::.:::: .: :.::.: :::::. :.:: .: : :. ::::.:::::::
CCDS36 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP
:: .:. :. :. .: ..::.:: ... :. ::::. ::: : .: .::.:
CCDS36 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP
70 80 90 100 110
110 120 130 140 150 160
pF1KE3 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV
.... ::. :::::: : : .:::::::
CCDS36 NMNNDPYMSNGSLSP-------------------------------PIPR--TSNKVPVV
120 130 140
170 180 190 200 210 220
pF1KE3 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG
: : :::::::::::.:::.::. : :.:.::. : :. : : ::: .:::::: ::
CCDS36 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE3 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV
:: ::::::::::::: ::::.:::..:.:..::::: ::.: :::::::::::
CCDS36 QITPPLGWQGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIV
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE3 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK
:: :::: ..: .: . .....::.: :.:::::::::::::::::::.::::::::
CCDS36 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE3 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS36 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQ
330 340 350 360 370 380
410 420 430 440 450
pF1KE3 GETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEAY
CCDS36 ESASGTGPRMTAAYI
390
455 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:57:53 2016 done: Sat Nov 5 01:57:53 2016
Total Scan time: 3.670 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]