Result of FASTA (ccds) for
pFN21AE3473
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3473, 1537 aa
1>>>pF1KE3473 1537 - 1537 aa - 1537 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.9590+/-0.00107; mu= -1.4371+/- 0.064
mean_var=286.5881+/-59.268, 0's: 0 Z-trim(112.6): 45 B-trim: 148 in 1/53
Lambda= 0.075761
statistics sampled from 13278 (13315) to 13278 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.409), width: 16
Scan time: 6.300
The best scores are: opt bits E(32554)
CCDS42460.1 DOT1L gene_id:84444|Hs108|chr19 (1537) 10123 1121.1 0
>>CCDS42460.1 DOT1L gene_id:84444|Hs108|chr19 (1537 aa)
initn: 10123 init1: 10123 opt: 10123 Z-score: 5990.0 bits: 1121.1 E(32554): 0
Smith-Waterman score: 10123; 100.0% identity (100.0% similar) in 1537 aa overlap (1-1537:1-1537)
10 20 30 40 50 60
pF1KE3 MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 GEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 GPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
1450 1460 1470 1480 1490 1500
1510 1520 1530
pF1KE3 VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN
:::::::::::::::::::::::::::::::::::::
CCDS42 VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN
1510 1520 1530
1537 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:10:23 2016 done: Mon Nov 7 18:10:24 2016
Total Scan time: 6.300 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]