Result of FASTA (omim) for
pFN21AE3434
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3434, 886 aa
1>>>pF1KE3434 886 - 886 aa - 886 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9976+/-0.000317; mu= 5.0232+/- 0.020
mean_var=176.3353+/-34.698, 0's: 0 Z-trim(122.1): 209 B-trim: 0 in 0/58
Lambda= 0.096584
statistics sampled from 39481 (39699) to 39481 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.465), width: 16
Scan time: 15.270
The best scores are: opt bits E(85289)
NP_001104777 (OMIM: 600126) cAMP-specific 3',5'-cy ( 886) 5902 834.7 0
XP_016882354 (OMIM: 600126) PREDICTED: cAMP-specif ( 885) 5884 832.2 0
NP_001104778 (OMIM: 600126) cAMP-specific 3',5'-cy ( 860) 5164 731.9 3.2e-210
NP_001104779 (OMIM: 600126) cAMP-specific 3',5'-cy ( 825) 5158 731.0 5.5e-210
NP_001230050 (OMIM: 600126) cAMP-specific 3',5'-cy ( 864) 5150 729.9 1.2e-209
XP_011526356 (OMIM: 600126) PREDICTED: cAMP-specif ( 864) 5150 729.9 1.2e-209
XP_011526357 (OMIM: 600126) PREDICTED: cAMP-specif ( 657) 4275 607.9 4.9e-173
NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cycli ( 647) 4147 590.1 1.1e-167
XP_005259990 (OMIM: 600126) PREDICTED: cAMP-specif ( 582) 3873 551.9 3.2e-156
NP_001184150 (OMIM: 600129,606799,614613) cAMP-spe ( 507) 2203 319.2 3.2e-86
NP_001184152 (OMIM: 600129,606799,614613) cAMP-spe ( 518) 2203 319.2 3.2e-86
XP_016865060 (OMIM: 600129,606799,614613) PREDICTE ( 553) 2203 319.2 3.4e-86
XP_016865059 (OMIM: 600129,606799,614613) PREDICTE ( 553) 2203 319.2 3.4e-86
NP_001184151 (OMIM: 600129,606799,614613) cAMP-spe ( 585) 2203 319.2 3.6e-86
XP_011541779 (OMIM: 600129,606799,614613) PREDICTE ( 662) 2203 319.2 4e-86
XP_005248595 (OMIM: 600129,606799,614613) PREDICTE ( 673) 2203 319.2 4.1e-86
NP_006194 (OMIM: 600129,606799,614613) cAMP-specif ( 673) 2203 319.2 4.1e-86
NP_001184149 (OMIM: 600129,606799,614613) cAMP-spe ( 679) 2203 319.2 4.1e-86
NP_001184148 (OMIM: 600129,606799,614613) cAMP-spe ( 687) 2203 319.2 4.1e-86
XP_016865058 (OMIM: 600129,606799,614613) PREDICTE ( 699) 2203 319.2 4.2e-86
XP_005248594 (OMIM: 600129,606799,614613) PREDICTE ( 699) 2203 319.2 4.2e-86
XP_016865057 (OMIM: 600129,606799,614613) PREDICTE ( 738) 2203 319.2 4.4e-86
XP_016865056 (OMIM: 600129,606799,614613) PREDICTE ( 743) 2203 319.2 4.4e-86
NP_001184147 (OMIM: 600129,606799,614613) cAMP-spe ( 745) 2203 319.2 4.4e-86
XP_016865055 (OMIM: 600129,606799,614613) PREDICTE ( 748) 2203 319.2 4.5e-86
XP_011541773 (OMIM: 600129,606799,614613) PREDICTE ( 748) 2203 319.2 4.5e-86
XP_011541775 (OMIM: 600129,606799,614613) PREDICTE ( 748) 2203 319.2 4.5e-86
NP_001159371 (OMIM: 600129,606799,614613) cAMP-spe ( 748) 2203 319.2 4.5e-86
XP_011541772 (OMIM: 600129,606799,614613) PREDICTE ( 797) 2203 319.3 4.7e-86
XP_016865054 (OMIM: 600129,606799,614613) PREDICTE ( 797) 2203 319.3 4.7e-86
XP_011541771 (OMIM: 600129,606799,614613) PREDICTE ( 797) 2203 319.3 4.7e-86
NP_001098101 (OMIM: 600129,606799,614613) cAMP-spe ( 809) 2203 319.3 4.8e-86
NP_001284371 (OMIM: 600127) cAMP-specific 3',5'-cy ( 503) 2174 315.1 5.2e-85
XP_005270982 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 2174 315.1 5.3e-85
XP_005270981 (OMIM: 600127) PREDICTED: cAMP-specif ( 517) 2174 315.1 5.3e-85
XP_011539868 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 2174 315.1 5.4e-85
XP_016856935 (OMIM: 600127) PREDICTED: cAMP-specif ( 530) 2174 315.1 5.4e-85
XP_006710743 (OMIM: 600127) PREDICTED: cAMP-specif ( 531) 2174 315.1 5.5e-85
NP_001032416 (OMIM: 600127) cAMP-specific 3',5'-cy ( 564) 2174 315.2 5.7e-85
XP_016856934 (OMIM: 600127) PREDICTED: cAMP-specif ( 597) 2174 315.2 6e-85
NP_001284369 (OMIM: 600127) cAMP-specific 3',5'-cy ( 644) 2174 315.2 6.4e-85
NP_001284370 (OMIM: 600127) cAMP-specific 3',5'-cy ( 661) 2174 315.2 6.6e-85
NP_001032417 (OMIM: 600127) cAMP-specific 3',5'-cy ( 721) 2174 315.2 7.1e-85
NP_002591 (OMIM: 600127) cAMP-specific 3',5'-cycli ( 736) 2174 315.2 7.2e-85
NP_001032418 (OMIM: 600127) cAMP-specific 3',5'-cy ( 736) 2174 315.2 7.2e-85
XP_011526360 (OMIM: 600128) PREDICTED: cAMP-specif ( 481) 2070 300.6 1.2e-80
NP_001092289 (OMIM: 600128) cAMP-specific 3',5'-cy ( 606) 2070 300.7 1.4e-80
XP_011526358 (OMIM: 600128) PREDICTED: cAMP-specif ( 606) 2070 300.7 1.4e-80
NP_001092288 (OMIM: 600128) cAMP-specific 3',5'-cy ( 680) 2070 300.7 1.6e-80
NP_000914 (OMIM: 600128) cAMP-specific 3',5'-cycli ( 712) 2070 300.7 1.6e-80
>>NP_001104777 (OMIM: 600126) cAMP-specific 3',5'-cyclic (886 aa)
initn: 5902 init1: 5902 opt: 5902 Z-score: 4450.8 bits: 834.7 E(85289): 0
Smith-Waterman score: 5902; 100.0% identity (100.0% similar) in 886 aa overlap (1-886:1-886)
10 20 30 40 50 60
pF1KE3 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
790 800 810 820 830 840
850 860 870 880
pF1KE3 STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
850 860 870 880
>>XP_016882354 (OMIM: 600126) PREDICTED: cAMP-specific 3 (885 aa)
initn: 4391 init1: 4391 opt: 5884 Z-score: 4437.2 bits: 832.2 E(85289): 0
Smith-Waterman score: 5884; 99.9% identity (99.9% similar) in 886 aa overlap (1-886:1-885)
10 20 30 40 50 60
pF1KE3 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSE-TCQQLARETLEELDW
190 200 210 220 230
250 260 270 280 290 300
pF1KE3 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE3 ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
780 790 800 810 820 830
850 860 870 880
pF1KE3 STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
840 850 860 870 880
>>NP_001104778 (OMIM: 600126) cAMP-specific 3',5'-cyclic (860 aa)
initn: 5150 init1: 5150 opt: 5164 Z-score: 3895.2 bits: 731.9 E(85289): 3.2e-210
Smith-Waterman score: 5164; 95.4% identity (96.7% similar) in 830 aa overlap (59-886:37-860)
30 40 50 60 70 80
pF1KE3 PPQHLWRQPRTPIRIQQRGYSDSAERAERERQPHRP--IERADAMDTSDRPGLRTTRMSW
: :.:: . .. .: : .: :.
NP_001 LGRIPELQLVAFPVAVAAEDEAFLPEPLAPRAPRRPRSPPSSPVFFASPSPTFRR-RLRL
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE3 PSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESF
: . : .. ::.: :::::::::::::::::::::::::::::::::::::::
NP_001 LRSCQDLGR-QAWAGAG----FEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESF
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE3 LYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSN
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE3 KRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
190 200 210 220 230 240
270 280 290 300 310 320
pF1KE3 NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPV
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE3 PHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE3 GGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTH
370 380 390 400 410 420
450 460 470 480 490 500
pF1KE3 VLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
430 440 450 460 470 480
510 520 530 540 550 560
pF1KE3 LAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVT
490 500 510 520 530 540
570 580 590 600 610 620
pF1KE3 SSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGME
550 560 570 580 590 600
630 640 650 660 670 680
pF1KE3 ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQS
610 620 630 640 650 660
690 700 710 720 730 740
pF1KE3 PSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEAL
670 680 690 700 710 720
750 760 770 780 790 800
pF1KE3 DATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAV
730 740 750 760 770 780
810 820 830 840 850 860
pF1KE3 SHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTF
790 800 810 820 830 840
870 880
pF1KE3 GEDTSALPAPGGGGSGGDPT
::::::::::::::::::::
NP_001 GEDTSALPAPGGGGSGGDPT
850 860
>>NP_001104779 (OMIM: 600126) cAMP-specific 3',5'-cyclic (825 aa)
initn: 5158 init1: 5158 opt: 5158 Z-score: 3891.0 bits: 731.0 E(85289): 5.5e-210
Smith-Waterman score: 5158; 99.6% identity (99.6% similar) in 784 aa overlap (103-886:42-825)
80 90 100 110 120 130
pF1KE3 TSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLV
: : :::::::::::::::::::::::::
NP_001 RPPALALPPTGPESLTHFPFSDEDTRRHPPGRSVSFEAENGPTPSPGRSPLDSQASPGLV
20 30 40 50 60 70
140 150 160 170 180 190
pF1KE3 LHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVR
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE3 SNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYR
140 150 160 170 180 190
260 270 280 290 300 310
pF1KE3 SVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQ
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE3 APRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENL
260 270 280 290 300 310
380 390 400 410 420 430
pF1KE3 NKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAY
320 330 340 350 360 370
440 450 460 470 480 490
pF1KE3 HNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSEL
380 390 400 410 420 430
500 510 520 530 540 550
pF1KE3 ALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTL
440 450 460 470 480 490
560 570 580 590 600 610
pF1KE3 LADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAE
500 510 520 530 540 550
620 630 640 650 660 670
pF1KE3 FFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTL
560 570 580 590 600 610
680 690 700 710 720 730
pF1KE3 EDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQE
620 630 640 650 660 670
740 750 760 770 780 790
pF1KE3 ALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVA
680 690 700 710 720 730
800 810 820 830 840 850
pF1KE3 PDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREH
740 750 760 770 780 790
860 870 880
pF1KE3 QAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
::::::::::::::::::::::::::::::::::
NP_001 QAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
800 810 820
>>NP_001230050 (OMIM: 600126) cAMP-specific 3',5'-cyclic (864 aa)
initn: 5150 init1: 5150 opt: 5150 Z-score: 3884.6 bits: 729.9 E(85289): 1.2e-209
Smith-Waterman score: 5150; 100.0% identity (100.0% similar) in 779 aa overlap (108-886:86-864)
80 90 100 110 120 130
pF1KE3 GLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGA
::::::::::::::::::::::::::::::
NP_001 DPGVPLPPRPTTLPLLIPPRISITRAENDSFEAENGPTPSPGRSPLDSQASPGLVLHAGA
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE3 ATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE3 LTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEM
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE3 ASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPR
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 PSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGL
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE3 NIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLH
360 370 380 390 400 410
440 450 460 470 480 490
pF1KE3 AADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYN
420 430 440 450 460 470
500 510 520 530 540 550
pF1KE3 DESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLK
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 TMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQG
540 550 560 570 580 590
620 630 640 650 660 670
pF1KE3 DRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRD
600 610 620 630 640 650
680 690 700 710 720 730
pF1KE3 WYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQ
660 670 680 690 700 710
740 750 760 770 780 790
pF1KE3 GLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFS
720 730 740 750 760 770
800 810 820 830 840 850
pF1KE3 SREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKR
780 790 800 810 820 830
860 870 880
pF1KE3 ACSACAGTFGEDTSALPAPGGGGSGGDPT
:::::::::::::::::::::::::::::
NP_001 ACSACAGTFGEDTSALPAPGGGGSGGDPT
840 850 860
>>XP_011526356 (OMIM: 600126) PREDICTED: cAMP-specific 3 (864 aa)
initn: 5150 init1: 5150 opt: 5150 Z-score: 3884.6 bits: 729.9 E(85289): 1.2e-209
Smith-Waterman score: 5150; 100.0% identity (100.0% similar) in 779 aa overlap (108-886:86-864)
80 90 100 110 120 130
pF1KE3 GLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGA
::::::::::::::::::::::::::::::
XP_011 DPGVPLPPRPTTLPLLIPPRISITRAENDSFEAENGPTPSPGRSPLDSQASPGLVLHAGA
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE3 ATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE3 LTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEM
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE3 ASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPR
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 PSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGL
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE3 NIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLH
360 370 380 390 400 410
440 450 460 470 480 490
pF1KE3 AADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYN
420 430 440 450 460 470
500 510 520 530 540 550
pF1KE3 DESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLK
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 TMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQG
540 550 560 570 580 590
620 630 640 650 660 670
pF1KE3 DRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRD
600 610 620 630 640 650
680 690 700 710 720 730
pF1KE3 WYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQ
660 670 680 690 700 710
740 750 760 770 780 790
pF1KE3 GLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFS
720 730 740 750 760 770
800 810 820 830 840 850
pF1KE3 SREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKR
780 790 800 810 820 830
860 870 880
pF1KE3 ACSACAGTFGEDTSALPAPGGGGSGGDPT
:::::::::::::::::::::::::::::
XP_011 ACSACAGTFGEDTSALPAPGGGGSGGDPT
840 850 860
>>XP_011526357 (OMIM: 600126) PREDICTED: cAMP-specific 3 (657 aa)
initn: 4275 init1: 4275 opt: 4275 Z-score: 3227.6 bits: 607.9 E(85289): 4.9e-173
Smith-Waterman score: 4275; 100.0% identity (100.0% similar) in 643 aa overlap (1-643:1-643)
10 20 30 40 50 60
pF1KE3 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
:::::::::::::::::::::::::::::::::::::::::::
XP_011 LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVQARGIDGRAQGGFY
610 620 630 640 650
670 680 690 700 710 720
pF1KE3 VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
>>NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cyclic ph (647 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3131.3 bits: 590.1 E(85289): 1.1e-167
Smith-Waterman score: 4147; 99.8% identity (100.0% similar) in 626 aa overlap (261-886:22-647)
240 250 260 270 280 290
pF1KE3 ARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTT
.:::::::::::::::::::::::::::::
NP_006 MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTT
10 20 30 40 50
300 310 320 330 340 350
pF1KE3 FLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNS
60 70 80 90 100 110
360 370 380 390 400 410
pF1KE3 NIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRI
120 130 140 150 160 170
420 430 440 450 460 470
pF1KE3 PVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAA
180 190 200 210 220 230
480 490 500 510 520 530
pF1KE3 AIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQR
240 250 260 270 280 290
540 550 560 570 580 590
pF1KE3 QSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCA
300 310 320 330 340 350
600 610 620 630 640 650
pF1KE3 DLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIV
360 370 380 390 400 410
660 670 680 690 700 710
pF1KE3 HPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFE
420 430 440 450 460 470
720 730 740 750 760 770
pF1KE3 LTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASL
480 490 500 510 520 530
780 790 800 810 820 830
pF1KE3 EAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVS
540 550 560 570 580 590
840 850 860 870 880
pF1KE3 EHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
600 610 620 630 640
>>XP_005259990 (OMIM: 600126) PREDICTED: cAMP-specific 3 (582 aa)
initn: 3873 init1: 3873 opt: 3873 Z-score: 2925.6 bits: 551.9 E(85289): 3.2e-156
Smith-Waterman score: 3873; 100.0% identity (100.0% similar) in 582 aa overlap (305-886:1-582)
280 290 300 310 320 330
pF1KE3 EMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQ
::::::::::::::::::::::::::::::
XP_005 MKEREKQQAPRPRPSQPPPPPVPHLQPMSQ
10 20 30
340 350 360 370 380 390
pF1KE3 ITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCI
40 50 60 70 80 90
400 410 420 430 440 450
pF1KE3 MYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPAL
100 110 120 130 140 150
460 470 480 490 500 510
pF1KE3 DAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLL
160 170 180 190 200 210
520 530 540 550 560 570
pF1KE3 QEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLD
220 230 240 250 260 270
580 590 600 610 620 630
pF1KE3 NYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKH
280 290 300 310 320 330
640 650 660 670 680 690
pF1KE3 TASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEE
340 350 360 370 380 390
700 710 720 730 740 750
pF1KE3 SRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEA
400 410 420 430 440 450
760 770 780 790 800 810
pF1KE3 SPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSAL
460 470 480 490 500 510
820 830 840 850 860 870
pF1KE3 ALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALP
520 530 540 550 560 570
880
pF1KE3 APGGGGSGGDPT
::::::::::::
XP_005 APGGGGSGGDPT
580
>>NP_001184150 (OMIM: 600129,606799,614613) cAMP-specifi (507 aa)
initn: 2480 init1: 2119 opt: 2203 Z-score: 1669.0 bits: 319.2 E(85289): 3.2e-86
Smith-Waterman score: 2462; 74.3% identity (88.0% similar) in 510 aa overlap (257-759:1-491)
230 240 250 260 270 280
pF1KE3 CQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEY
:::.:::::::::::::::::::::::::.
NP_001 MASNKFKRMLNRELTHLSEMSRSGNQVSEF
10 20 30
290 300 310 320 330 340
pF1KE3 ISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNS
::.::::::.::::::::.::.::.. .:::::.:.::::::.:
NP_001 ISNTFLDKQHEVEIPSPTQKEKEKKK-----------------RPMSQISGVKKLMHSSS
40 50 60 70
350 360 370 380 390 400
pF1KE3 LNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLK
:.::.::::::::.::..::.:::..:::::..: ... .:.: :: ::. :::::::::
NP_001 LTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLK
80 90 100 110 120 130
410 420 430 440 450 460
pF1KE3 KFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAA
:.:::::..::..::::::::::::::..:::::.:::::::.::::.:::::::::::
NP_001 TFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAA
140 150 160 170 180 190
470 480 490 500 510 520
pF1KE3 LFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLS
.::.:::::::::::::::::::::::::::: :::::::::::::::::.::::::::.
NP_001 IFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLT
200 210 220 230 240 250
530 540 550 560 570 580
pF1KE3 KRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNM
:.:::::::::::.::::::::::.::::::::::::::::::::::::::::::::.::
NP_001 KKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
260 270 280 290 300 310
590 600 610 620 630 640
pF1KE3 VHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFI
:::::::::::::.:::::::::: :::.:::::::::::::::::::.:::::::::::
NP_001 VHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFI
320 330 340 350 360 370
650 660 670 680 690 700
pF1KE3 DYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDK
::::::::::::::::::::.:::::::::.:: :.: ::::: :.. .: . .:
NP_001 DYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEG--RQGQTEK
380 390 400 410 420 430
710 720 730 740 750
pF1KE3 FQFELTLEEEEE---EEISMAQIP----CTAQEALTAQGLSGVEEALDATIAWEASPAQE
:::::::::. : :. : .:. :. ...: .: ..: :: . :: .:
NP_001 FQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEE
440 450 460 470 480 490
760 770 780 790 800 810
pF1KE3 SLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSP
NP_001 ESQPEACVIDDRSPDT
500
886 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:14:59 2016 done: Mon Nov 7 03:15:01 2016
Total Scan time: 15.270 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]