Result of FASTA (omim) for
pFN21AE3422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3422, 493 aa
1>>>pF1KE3422 493 - 493 aa - 493 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.8861+/-0.000614; mu= -31.7133+/- 0.037
mean_var=723.4717+/-160.027, 0's: 0 Z-trim(114.7): 1640 B-trim: 0 in 0/61
Lambda= 0.047683
statistics sampled from 22478 (24662) to 22478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.289), width: 16
Scan time: 8.210
The best scores are: opt bits E(85289)
XP_016864299 (OMIM: 603442) PREDICTED: cyclin-depe ( 493) 3318 244.6 4.8e-64
NP_003939 (OMIM: 603442) cyclin-dependent kinase-l ( 493) 3318 244.6 4.8e-64
NP_001317653 (OMIM: 603442) cyclin-dependent kinas ( 570) 3176 234.9 4.7e-61
XP_016864298 (OMIM: 603442) PREDICTED: cyclin-depe ( 570) 3176 234.9 4.7e-61
XP_006714469 (OMIM: 603442) PREDICTED: cyclin-depe ( 530) 3173 234.7 5.1e-61
XP_016864300 (OMIM: 603442) PREDICTED: cyclin-depe ( 479) 3167 234.2 6.4e-61
NP_057592 (OMIM: 608459) cyclin-dependent kinase-l ( 455) 1322 107.3 9.9e-23
NP_001107047 (OMIM: 608459) cyclin-dependent kinas ( 592) 1322 107.4 1.2e-22
XP_016865024 (OMIM: 608459) PREDICTED: cyclin-depe ( 592) 1322 107.4 1.2e-22
XP_016865021 (OMIM: 608459) PREDICTED: cyclin-depe ( 607) 1322 107.4 1.2e-22
XP_005268214 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 1260 102.9 1.6e-21
XP_016877218 (OMIM: 603441) PREDICTED: cyclin-depe ( 358) 1260 102.9 1.6e-21
NP_004187 (OMIM: 603441) cyclin-dependent kinase-l ( 358) 1260 102.9 1.6e-21
XP_016877221 (OMIM: 603441) PREDICTED: cyclin-depe ( 279) 1156 95.6 1.9e-19
NP_001269165 (OMIM: 603441) cyclin-dependent kinas ( 276) 1150 95.2 2.5e-19
XP_016877219 (OMIM: 603441) PREDICTED: cyclin-depe ( 301) 1150 95.2 2.7e-19
XP_016877220 (OMIM: 603441) PREDICTED: cyclin-depe ( 301) 1150 95.2 2.7e-19
XP_005268216 (OMIM: 603441) PREDICTED: cyclin-depe ( 301) 1150 95.2 2.7e-19
XP_016865016 (OMIM: 608459) PREDICTED: cyclin-depe ( 622) 1145 95.2 5.7e-19
NP_001310218 (OMIM: 300203,300672) cyclin-dependen ( 960) 1009 86.0 5.1e-16
NP_001032420 (OMIM: 300203,300672) cyclin-dependen (1030) 1009 86.1 5.3e-16
NP_003150 (OMIM: 300203,300672) cyclin-dependent k (1030) 1009 86.1 5.3e-16
XP_011535578 (OMIM: 603441) PREDICTED: cyclin-depe ( 308) 976 83.3 1.1e-15
XP_016865037 (OMIM: 608459) PREDICTED: cyclin-depe ( 307) 841 74.0 6.8e-13
XP_016865025 (OMIM: 608459) PREDICTED: cyclin-depe ( 538) 841 74.2 1e-12
XP_016865023 (OMIM: 608459) PREDICTED: cyclin-depe ( 602) 841 74.3 1.1e-12
XP_016865022 (OMIM: 608459) PREDICTED: cyclin-depe ( 604) 841 74.3 1.1e-12
XP_016865019 (OMIM: 608459) PREDICTED: cyclin-depe ( 617) 841 74.3 1.1e-12
XP_016865020 (OMIM: 608459) PREDICTED: cyclin-depe ( 617) 841 74.3 1.1e-12
XP_011541731 (OMIM: 608459) PREDICTED: cyclin-depe ( 619) 841 74.3 1.1e-12
XP_016865018 (OMIM: 608459) PREDICTED: cyclin-depe ( 619) 841 74.3 1.1e-12
XP_016865017 (OMIM: 608459) PREDICTED: cyclin-depe ( 619) 841 74.3 1.1e-12
XP_016865013 (OMIM: 608459) PREDICTED: cyclin-depe ( 634) 841 74.3 1.1e-12
XP_016865015 (OMIM: 608459) PREDICTED: cyclin-depe ( 634) 841 74.3 1.1e-12
XP_016865014 (OMIM: 608459) PREDICTED: cyclin-depe ( 634) 841 74.3 1.1e-12
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 765 68.8 2.5e-11
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 765 68.8 2.5e-11
XP_005268217 (OMIM: 603441) PREDICTED: cyclin-depe ( 244) 745 67.3 5.6e-11
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 744 67.3 6.8e-11
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 744 67.3 6.8e-11
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 744 67.3 6.8e-11
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 731 66.4 1.2e-10
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 664 61.9 3.4e-09
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 667 62.3 4e-09
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 667 62.3 4e-09
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 667 62.3 4e-09
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 660 61.8 5.6e-09
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346) 651 61.0 6.4e-09
XP_016870050 (OMIM: 610076) PREDICTED: cyclin-depe ( 351) 644 60.5 9e-09
XP_016866355 (OMIM: 154235,614181) PREDICTED: seri ( 439) 645 60.7 1e-08
>>XP_016864299 (OMIM: 603442) PREDICTED: cyclin-dependen (493 aa)
initn: 3318 init1: 3318 opt: 3318 Z-score: 1270.7 bits: 244.6 E(85289): 4.8e-64
Smith-Waterman score: 3318; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
430 440 450 460 470 480
490
pF1KE3 DSGADLPQMEHQH
:::::::::::::
XP_016 DSGADLPQMEHQH
490
>>NP_003939 (OMIM: 603442) cyclin-dependent kinase-like (493 aa)
initn: 3318 init1: 3318 opt: 3318 Z-score: 1270.7 bits: 244.6 E(85289): 4.8e-64
Smith-Waterman score: 3318; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
430 440 450 460 470 480
490
pF1KE3 DSGADLPQMEHQH
:::::::::::::
NP_003 DSGADLPQMEHQH
490
>>NP_001317653 (OMIM: 603442) cyclin-dependent kinase-li (570 aa)
initn: 3176 init1: 3176 opt: 3176 Z-score: 1217.1 bits: 234.9 E(85289): 4.7e-61
Smith-Waterman score: 3176; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSSEKNLF
430 440 450 460 470 480
490
pF1KE3 DSGADLPQMEHQH
NP_001 WASKKRREYSRTDVRLPELNYNHLPELRALGGIARNSRLTKKESKILSESRIPSLAAIDL
490 500 510 520 530 540
>>XP_016864298 (OMIM: 603442) PREDICTED: cyclin-dependen (570 aa)
initn: 3176 init1: 3176 opt: 3176 Z-score: 1217.1 bits: 234.9 E(85289): 4.7e-61
Smith-Waterman score: 3176; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSSEKNLF
430 440 450 460 470 480
490
pF1KE3 DSGADLPQMEHQH
XP_016 WASKKRREYSRTDVRLPELNYNHLPELRALGGIARNSRLTKKESKILSESRIPSLAAIDL
490 500 510 520 530 540
>>XP_006714469 (OMIM: 603442) PREDICTED: cyclin-dependen (530 aa)
initn: 3173 init1: 3173 opt: 3173 Z-score: 1216.4 bits: 234.7 E(85289): 5.1e-61
Smith-Waterman score: 3194; 93.0% identity (93.0% similar) in 525 aa overlap (1-488:1-525)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLV-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVTRNSRLT
430 440 450 460 470 480
480 490
pF1KE3 ------------------------------SGPPLSDDSGADLPQMEHQH
:::::::::::::::
XP_006 KKESKILSESRIPSLAAIDLHTPSITLHQVSGPPLSDDSGADLPQMEHQH
490 500 510 520 530
>>XP_016864300 (OMIM: 603442) PREDICTED: cyclin-dependen (479 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 1214.7 bits: 234.2 E(85289): 6.4e-61
Smith-Waterman score: 3167; 99.8% identity (100.0% similar) in 473 aa overlap (1-473:1-473)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLMMLLHLR
430 440 450 460 470
490
pF1KE3 DSGADLPQMEHQH
>>NP_057592 (OMIM: 608459) cyclin-dependent kinase-like (455 aa)
initn: 1289 init1: 1124 opt: 1322 Z-score: 529.1 bits: 107.3 E(85289): 9.9e-23
Smith-Waterman score: 1332; 46.9% identity (75.8% similar) in 454 aa overlap (1-430:1-449)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
:: ::.:: ::::::: ::::..:.::.::::: : : ... :.::::::::.:::..:
NP_057 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::.:: ..::. .:::::.:::.::.:. . .::. . ..::::::. .: . ::.
NP_057 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::..:::::::::::::::..:::::::::::::::.. :..::
NP_057 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
: ::.::.::.. :: :.: .:..::.: :..:.. .::: :. :..:.:.:.:::: :
NP_057 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
:.... . ...::::. .. :... ::.::: : ..::::..: ::: :.: ::
NP_057 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL
240 250 260 270 280 290
310 320 330 340 350
pF1KE3 QLKVQKDARNVSLSK-KSQNRKKEKEKDDSLVEERKTLVV-----QDTNADPKIKDYKL-
. :. ..:. :: : : .....: .::. . .::. .. . . : :. :.
NP_057 KAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVR
300 310 320 330 340 350
360 370 380 390
pF1KE3 -FKIKGSKIDGEKAEK-------GNRASNASCLH----DSRT----SHNKIVPSTSLKDC
.:.::.. : . .: :.. .: . .: :.. : : ::: .:
NP_057 VIKVKGGRGDISEPKKKEYEGGLGQQDANEN-VHPMSPDTKLVTIEPPNPINPST---NC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 SNVSVDHTRNPSVAIPPLT-HNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKP
.... . . ::..::.. : . .: ...:..
NP_057 NGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVR
420 430 440 450
460 470 480 490
pF1KE3 NRHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH
>>NP_001107047 (OMIM: 608459) cyclin-dependent kinase-li (592 aa)
initn: 1289 init1: 1124 opt: 1322 Z-score: 527.6 bits: 107.4 E(85289): 1.2e-22
Smith-Waterman score: 1349; 45.3% identity (73.8% similar) in 488 aa overlap (1-463:1-483)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
:: ::.:: ::::::: ::::..:.::.::::: : : ... :.::::::::.:::..:
NP_001 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::.:: ..::. .:::::.:::.::.:. . .::. . ..::::::. .: . ::.
NP_001 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::..:::::::::::::::..:::::::::::::::.. :..::
NP_001 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
: ::.::.::.. :: :.: .:..::.: :..:.. .::: :. :..:.:.:.:::: :
NP_001 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
:.... . ...::::. .. :... ::.::: : ..::::..: ::: :.: ::
NP_001 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL
240 250 260 270 280 290
310 320 330 340 350
pF1KE3 QLKVQKDARNVSLSK-KSQNRKKEKEKDDSLVEERKTLVV-----QDTNADPKIKDYKL-
. :. ..:. :: : : .....: .::. . .::. .. . . : :. :.
NP_001 KAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVR
300 310 320 330 340 350
360 370 380 390
pF1KE3 -FKIKGSKIDGEKAEK-------GNRASNASCLH----DSRT----SHNKIVPSTSLKDC
.:.::.. : . .: :.. .: . .: :.. : : ::: .:
NP_001 VIKVKGGRGDISEPKKKEYEGGLGQQDANEN-VHPMSPDTKLVTIEPPNPINPST---NC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 SNVSVDHTRNPSVAIPPLT-HNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKP
.... . . ::..::.. : . .: ...:.. .. . ..:.. :: : :
NP_001 NGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMP
420 430 440 450 460 470
460 470 480 490
pF1KE3 N-RHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH
: :. :
NP_001 NSRQEDPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKD
480 490 500 510 520 530
>>XP_016865024 (OMIM: 608459) PREDICTED: cyclin-dependen (592 aa)
initn: 1289 init1: 1124 opt: 1322 Z-score: 527.6 bits: 107.4 E(85289): 1.2e-22
Smith-Waterman score: 1349; 45.3% identity (73.8% similar) in 488 aa overlap (1-463:1-483)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
:: ::.:: ::::::: ::::..:.::.::::: : : ... :.::::::::.:::..:
XP_016 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::.:: ..::. .:::::.:::.::.:. . .::. . ..::::::. .: . ::.
XP_016 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::..:::::::::::::::..:::::::::::::::.. :..::
XP_016 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
: ::.::.::.. :: :.: .:..::.: :..:.. .::: :. :..:.:.:.:::: :
XP_016 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
:.... . ...::::. .. :... ::.::: : ..::::..: ::: :.: ::
XP_016 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL
240 250 260 270 280 290
310 320 330 340 350
pF1KE3 QLKVQKDARNVSLSK-KSQNRKKEKEKDDSLVEERKTLVV-----QDTNADPKIKDYKL-
. :. ..:. :: : : .....: .::. . .::. .. . . : :. :.
XP_016 KAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVR
300 310 320 330 340 350
360 370 380 390
pF1KE3 -FKIKGSKIDGEKAEK-------GNRASNASCLH----DSRT----SHNKIVPSTSLKDC
.:.::.. : . .: :.. .: . .: :.. : : ::: .:
XP_016 VIKVKGGRGDISEPKKKEYEGGLGQQDANEN-VHPMSPDTKLVTIEPPNPINPST---NC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 SNVSVDHTRNPSVAIPPLT-HNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKP
.... . . ::..::.. : . .: ...:.. .. . ..:.. :: : :
XP_016 NGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMP
420 430 440 450 460 470
460 470 480 490
pF1KE3 N-RHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH
: :. :
XP_016 NSRQEDPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKD
480 490 500 510 520 530
>>XP_016865021 (OMIM: 608459) PREDICTED: cyclin-dependen (607 aa)
initn: 1289 init1: 1124 opt: 1322 Z-score: 527.5 bits: 107.4 E(85289): 1.2e-22
Smith-Waterman score: 1349; 45.3% identity (73.8% similar) in 488 aa overlap (1-463:1-483)
10 20 30 40 50 60
pF1KE3 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
:: ::.:: ::::::: ::::..:.::.::::: : : ... :.::::::::.:::..:
XP_016 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
::::::.:: ..::. .:::::.:::.::.:. . .::. . ..::::::. .: . ::.
XP_016 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
::::::::::::::::::..:::::::::::::::..:::::::::::::::.. :..::
XP_016 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
: ::.::.::.. :: :.: .:..::.: :..:.. .::: :. :..:.:.:.:::: :
XP_016 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
:.... . ...::::. .. :... ::.::: : ..::::..: ::: :.: ::
XP_016 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL
240 250 260 270 280 290
310 320 330 340 350
pF1KE3 QLKVQKDARNVSLSK-KSQNRKKEKEKDDSLVEERKTLVV-----QDTNADPKIKDYKL-
. :. ..:. :: : : .....: .::. . .::. .. . . : :. :.
XP_016 KAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVR
300 310 320 330 340 350
360 370 380 390
pF1KE3 -FKIKGSKIDGEKAEK-------GNRASNASCLH----DSRT----SHNKIVPSTSLKDC
.:.::.. : . .: :.. .: . .: :.. : : ::: .:
XP_016 VIKVKGGRGDISEPKKKEYEGGLGQQDANEN-VHPMSPDTKLVTIEPPNPINPST---NC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 SNVSVDHTRNPSVAIPPLT-HNLSAVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKP
.... . . ::..::.. : . .: ...:.. .. . ..:.. :: : :
XP_016 NGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMP
420 430 440 450 460 470
460 470 480 490
pF1KE3 N-RHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH
: :. :
XP_016 NSRQEDPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKD
480 490 500 510 520 530
493 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:43:26 2016 done: Sun Nov 6 04:43:27 2016
Total Scan time: 8.210 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]