Result of FASTA (ccds) for
pFN21AE3407
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3407, 284 aa
1>>>pF1KE3407 284 - 284 aa - 284 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5657+/-0.000744; mu= 14.1402+/- 0.045
mean_var=72.4312+/-14.345, 0's: 0 Z-trim(108.7): 24 B-trim: 0 in 0/51
Lambda= 0.150699
statistics sampled from 10342 (10365) to 10342 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.318), width: 16
Scan time: 2.380
The best scores are: opt bits E(32554)
CCDS43056.1 METTL6 gene_id:131965|Hs108|chr3 ( 284) 1924 427.2 6.7e-120
CCDS77706.1 METTL6 gene_id:131965|Hs108|chr3 ( 239) 1111 250.4 9.4e-67
CCDS5803.2 METTL2B gene_id:55798|Hs108|chr7 ( 378) 602 139.8 2.8e-33
CCDS45752.1 METTL2A gene_id:339175|Hs108|chr17 ( 378) 597 138.7 6e-33
CCDS2242.2 METTL8 gene_id:79828|Hs108|chr2 ( 407) 549 128.3 8.9e-30
CCDS82531.1 METTL8 gene_id:79828|Hs108|chr2 ( 241) 259 65.1 5.5e-11
CCDS82532.1 METTL8 gene_id:79828|Hs108|chr2 ( 291) 259 65.2 6.4e-11
>>CCDS43056.1 METTL6 gene_id:131965|Hs108|chr3 (284 aa)
initn: 1924 init1: 1924 opt: 1924 Z-score: 2266.1 bits: 427.2 E(32554): 6.7e-120
Smith-Waterman score: 1924; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284)
10 20 30 40 50 60
pF1KE3 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
190 200 210 220 230 240
250 260 270 280
pF1KE3 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
250 260 270 280
>>CCDS77706.1 METTL6 gene_id:131965|Hs108|chr3 (239 aa)
initn: 1111 init1: 1111 opt: 1111 Z-score: 1311.9 bits: 250.4 E(32554): 9.4e-67
Smith-Waterman score: 1507; 84.2% identity (84.2% similar) in 284 aa overlap (1-284:1-239)
10 20 30 40 50 60
pF1KE3 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
:::::::::::::::
CCDS77 HWTTREFEELRSCRE---------------------------------------------
70
130 140 150 160 170 180
pF1KE3 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE3 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
140 150 160 170 180 190
250 260 270 280
pF1KE3 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
::::::::::::::::::::::::::::::::::::::::::::
CCDS77 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
200 210 220 230
>>CCDS5803.2 METTL2B gene_id:55798|Hs108|chr7 (378 aa)
initn: 712 init1: 517 opt: 602 Z-score: 710.8 bits: 139.8 E(32554): 2.8e-33
Smith-Waterman score: 602; 47.9% identity (69.7% similar) in 211 aa overlap (64-269:162-372)
40 50 60 70 80 90
pF1KE3 QQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCR-EFEDQKLT--MLEAGCGV
:... .:. : :: .. : .::.::::
CCDS58 GPGLIMEEQHKCSSKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGV
140 150 160 170 180 190
100 110 120 130 140
pF1KE3 GNCLFPLLE--EDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPP
:: .::.:. .::..:.: :::: ::: :. : :: :: .: :: .. ::
CCDS58 GNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPK
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE3 ESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGE
:.:...:::::::: ::::. ... . ..:::: ::.:::: :: :.:::: .. :.
CCDS58 GSLDIIILIFVLSAVVPDKMQKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSG
260 270 280 290 300 310
210 220 230 240 250 260
pF1KE3 NFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFLK
::::: :::: ::::.. : :: .: :.: : : ::. . : . ::..: :. :
CCDS58 NFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCK
320 330 340 350 360 370
270 280
pF1KE3 PPKNPSPVVLGLDPKS
:
CCDS58 PLLSSTS
>>CCDS45752.1 METTL2A gene_id:339175|Hs108|chr17 (378 aa)
initn: 707 init1: 512 opt: 597 Z-score: 705.0 bits: 138.7 E(32554): 6e-33
Smith-Waterman score: 597; 46.9% identity (69.7% similar) in 211 aa overlap (64-269:162-372)
40 50 60 70 80 90
pF1KE3 QQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCR-EFEDQKLT--MLEAGCGV
:... .:. : :: .. : .::.::::
CCDS45 GPGLIMEEQHKCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGV
140 150 160 170 180 190
100 110 120 130 140
pF1KE3 GNCLFPLLE--EDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPP
:: .::.:. .::..:.: :::: ::: :. : :: :: .: :: .. ::
CCDS45 GNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPK
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE3 ESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGE
:.:...:::::::. ::::. ... . ..:::: .:.:::: :: :.:::: .. :.
CCDS45 GSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSG
260 270 280 290 300 310
210 220 230 240 250 260
pF1KE3 NFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFLK
::::: :::: ::::.. : :: .: :.: : : ::. . : . ::..: :. :
CCDS45 NFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCK
320 330 340 350 360 370
270 280
pF1KE3 PPKNPSPVVLGLDPKS
:
CCDS45 PLLSSTS
>>CCDS2242.2 METTL8 gene_id:79828|Hs108|chr2 (407 aa)
initn: 675 init1: 488 opt: 549 Z-score: 648.1 bits: 128.3 E(32554): 8.9e-30
Smith-Waterman score: 549; 45.3% identity (70.5% similar) in 190 aa overlap (83-269:200-389)
60 70 80 90 100
pF1KE3 STNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLL---EEDPNIFAYAC
.::.:::.:: .::.: :..:. : : :
CCDS22 ESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCC
170 180 190 200 210 220
110 120 130 140 150 160
pF1KE3 DFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMH
::. :.: ::.. : . .: .: :. : : : .::..:.::::..:::.:.
CCDS22 DFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRMQ
230 240 250 260 270 280
170 180 190 200 210 220
pF1KE3 LVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQ
:.. . :.:::: .:::::: ::...:::: . :.:::::: ::::.:::: . .
CCDS22 GVVNRLSKLLKPGGMLLFRDYGRYDKTQLRFKKGHCLSENFYVRGDGTRAYFFTKGEVHS
290 300 310 320 330 340
230 240 250 260 270 280
pF1KE3 LFMDTGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
.: .. .: : : ::.:. . . ::..:.:: ::
CCDS22 MFCKASLDEKQNLVDRRLQVNRKKQVKMHRVWIQGKFQKPLHQTQNSSNMVSTLLSQD
350 360 370 380 390 400
>>CCDS82531.1 METTL8 gene_id:79828|Hs108|chr2 (241 aa)
initn: 385 init1: 198 opt: 259 Z-score: 310.8 bits: 65.1 E(32554): 5.5e-11
Smith-Waterman score: 259; 41.3% identity (68.5% similar) in 92 aa overlap (83-171:150-241)
60 70 80 90 100
pF1KE3 STNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLL---EEDPNIFAYAC
.::.:::.:: .::.: :..:. : : :
CCDS82 ESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCC
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE3 DFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMH
::. :.: ::.. : . .: .: :. : : : .::..:.::::..:::.
CCDS82 DFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRTL
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE3 LVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQ
..
CCDS82 FI
240
>>CCDS82532.1 METTL8 gene_id:79828|Hs108|chr2 (291 aa)
initn: 385 init1: 198 opt: 259 Z-score: 309.5 bits: 65.2 E(32554): 6.4e-11
Smith-Waterman score: 259; 41.3% identity (68.5% similar) in 92 aa overlap (83-171:200-291)
60 70 80 90 100
pF1KE3 STNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLL---EEDPNIFAYAC
.::.:::.:: .::.: :..:. : : :
CCDS82 ESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCC
170 180 190 200 210 220
110 120 130 140 150 160
pF1KE3 DFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMH
::. :.: ::.. : . .: .: :. : : : .::..:.::::..:::.
CCDS82 DFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRTL
230 240 250 260 270 280
170 180 190 200 210 220
pF1KE3 LVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQ
..
CCDS82 FI
290
284 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:46:53 2016 done: Fri Nov 4 12:46:53 2016
Total Scan time: 2.380 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]