Result of FASTA (omim) for
pFN21AE3403
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3403, 170 aa
1>>>pF1KE3403 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5355+/-0.000276; mu= 16.3603+/- 0.017
mean_var=60.1661+/-11.879, 0's: 0 Z-trim(118.8): 94 B-trim: 22 in 1/53
Lambda= 0.165348
statistics sampled from 32062 (32164) to 32062 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.377), width: 16
Scan time: 4.930
The best scores are: opt bits E(85289)
NP_068823 (OMIM: 602995) ubiquitin-conjugating enz ( 170) 1160 284.3 6.4e-77
NP_001244322 (OMIM: 602995) ubiquitin-conjugating ( 170) 1160 284.3 6.4e-77
NP_954595 (OMIM: 602995) ubiquitin-conjugating enz ( 170) 1160 284.3 6.4e-77
NP_001027459 (OMIM: 602995) ubiquitin-conjugating ( 147) 955 235.4 3e-62
NP_001244324 (OMIM: 602995) ubiquitin-conjugating ( 144) 936 230.8 6.9e-61
XP_011515885 (OMIM: 603001) PREDICTED: ubiquitin-c ( 173) 882 218.0 5.9e-57
NP_003341 (OMIM: 603001) ubiquitin-conjugating enz ( 145) 881 217.7 6.1e-57
XP_016869297 (OMIM: 603001) PREDICTED: ubiquitin-c ( 142) 873 215.8 2.3e-56
NP_001244327 (OMIM: 602995) ubiquitin-conjugating ( 105) 716 178.2 3.4e-45
NP_001269508 (OMIM: 602995) ubiquitin-conjugating ( 105) 716 178.2 3.4e-45
NP_001269505 (OMIM: 602995) ubiquitin-conjugating ( 105) 716 178.2 3.4e-45
NP_001244326 (OMIM: 602995) ubiquitin-conjugating ( 105) 716 178.2 3.4e-45
NP_001244328 (OMIM: 602995) ubiquitin-conjugating ( 105) 716 178.2 3.4e-45
XP_005251357 (OMIM: 603001) PREDICTED: ubiquitin-c ( 105) 642 160.6 7e-40
NP_071887 (OMIM: 602995) ubiquitin-conjugating enz ( 103) 614 153.9 7.1e-38
NP_001244323 (OMIM: 602995) ubiquitin-conjugating ( 103) 614 153.9 7.1e-38
NP_001269506 (OMIM: 602995) ubiquitin-conjugating ( 91) 607 152.2 2.1e-37
NP_001269504 (OMIM: 602995) ubiquitin-conjugating ( 91) 607 152.2 2.1e-37
NP_001269507 (OMIM: 602995) ubiquitin-conjugating ( 91) 607 152.2 2.1e-37
NP_001269509 (OMIM: 602995) ubiquitin-conjugating ( 64) 348 90.3 6.3e-19
NP_001244325 (OMIM: 602995) ubiquitin-conjugating ( 105) 348 90.4 9.1e-19
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 191 53.1 2.3e-07
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 191 53.2 2.8e-07
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 174 49.2 4.5e-06
NP_003333 (OMIM: 601569) ubiquitin-conjugating enz ( 170) 167 47.4 1.3e-05
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 166 47.2 1.4e-05
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 164 46.7 2e-05
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 164 46.7 2.1e-05
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 162 46.2 2.7e-05
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 162 46.3 3e-05
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 160 45.8 4.5e-05
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 160 45.8 4.7e-05
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 160 45.8 4.7e-05
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 157 45.0 6.1e-05
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 157 45.1 7e-05
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 155 44.4 7.2e-05
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 157 45.1 7.6e-05
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 151 43.5 0.00016
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 151 43.6 0.00017
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 149 43.2 0.00029
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 149 43.2 0.00029
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 149 43.2 0.00029
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 149 43.2 0.00029
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 149 43.2 0.00029
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 141 41.2 0.00088
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 138 40.4 0.0012
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 138 40.4 0.0012
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 138 40.4 0.0012
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 139 40.8 0.0013
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 138 40.5 0.0014
>>NP_068823 (OMIM: 602995) ubiquitin-conjugating enzyme (170 aa)
initn: 1160 init1: 1160 opt: 1160 Z-score: 1502.0 bits: 284.3 E(85289): 6.4e-77
Smith-Waterman score: 1160; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_001244322 (OMIM: 602995) ubiquitin-conjugating enzy (170 aa)
initn: 1160 init1: 1160 opt: 1160 Z-score: 1502.0 bits: 284.3 E(85289): 6.4e-77
Smith-Waterman score: 1160; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_954595 (OMIM: 602995) ubiquitin-conjugating enzyme (170 aa)
initn: 1160 init1: 1160 opt: 1160 Z-score: 1502.0 bits: 284.3 E(85289): 6.4e-77
Smith-Waterman score: 1160; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
130 140 150 160 170
>>NP_001027459 (OMIM: 602995) ubiquitin-conjugating enzy (147 aa)
initn: 955 init1: 955 opt: 955 Z-score: 1238.5 bits: 235.4 E(85289): 3e-62
Smith-Waterman score: 955; 100.0% identity (100.0% similar) in 140 aa overlap (31-170:8-147)
10 20 30 40 50 60
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
NP_001 MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30
70 80 90 100 110 120
pF1KE3 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
100 110 120 130 140
>>NP_001244324 (OMIM: 602995) ubiquitin-conjugating enzy (144 aa)
initn: 936 init1: 936 opt: 936 Z-score: 1214.2 bits: 230.8 E(85289): 6.9e-61
Smith-Waterman score: 936; 100.0% identity (100.0% similar) in 137 aa overlap (34-170:8-144)
10 20 30 40 50 60
pF1KE3 EVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDD
::::::::::::::::::::::::::::::
NP_001 MAATTGSVPRNFRLLEELEEGQKGVGDGTVSWGLEDD
10 20 30
70 80 90 100 110 120
pF1KE3 EDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVV
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 DPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
100 110 120 130 140
>>XP_011515885 (OMIM: 603001) PREDICTED: ubiquitin-conju (173 aa)
initn: 910 init1: 881 opt: 882 Z-score: 1143.5 bits: 218.0 E(85289): 5.9e-57
Smith-Waterman score: 882; 90.8% identity (96.5% similar) in 141 aa overlap (30-170:33-173)
10 20 30 40 50
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWG
.:::::::::::::::::::::::::::::
XP_011 VGAHVEEEETAGDKDVEEGVPFPGELVWNREGVKVPRNFRLLEELEEGQKGVGDGTVSWG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 LEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSS
:::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:
XP_011 LEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
.:.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
XP_011 SGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
130 140 150 160 170
>>NP_003341 (OMIM: 603001) ubiquitin-conjugating enzyme (145 aa)
initn: 906 init1: 881 opt: 881 Z-score: 1143.2 bits: 217.7 E(85289): 6.1e-57
Smith-Waterman score: 881; 91.4% identity (96.4% similar) in 140 aa overlap (31-170:6-145)
10 20 30 40 50 60
pF1KE3 MPGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
::::::::::::::::::::::::::::::
NP_003 MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGL
10 20 30
70 80 90 100 110 120
pF1KE3 EDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSN
::::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:.
NP_003 EDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSS
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 GVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
:.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
NP_003 GMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
100 110 120 130 140
>>XP_016869297 (OMIM: 603001) PREDICTED: ubiquitin-conju (142 aa)
initn: 885 init1: 873 opt: 873 Z-score: 1133.0 bits: 215.8 E(85289): 2.3e-56
Smith-Waterman score: 873; 91.4% identity (96.4% similar) in 139 aa overlap (32-170:4-142)
10 20 30 40 50 60
pF1KE3 PGEVQASYLKSQSKLSDEGRLEPRKFHCKGVKVPRNFRLLEELEEGQKGVGDGTVSWGLE
::::::::::::::::::::::::::::::
XP_016 MPRVKVPRNFRLLEELEEGQKGVGDGTVSWGLE
10 20 30
70 80 90 100 110 120
pF1KE3 DDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNG
:::::::::::::::::::: :::::::::.::::::::::: :::::::::::.:.:.:
XP_016 DDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSG
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 VVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
.:: :.: ::::::::::::::::::::::::::::::::::::: :.:
XP_016 MVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
100 110 120 130 140
>>NP_001244327 (OMIM: 602995) ubiquitin-conjugating enzy (105 aa)
initn: 716 init1: 716 opt: 716 Z-score: 932.4 bits: 178.2 E(85289): 3.4e-45
Smith-Waterman score: 716; 100.0% identity (100.0% similar) in 105 aa overlap (66-170:1-105)
40 50 60 70 80 90
pF1KE3 RNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECG
::::::::::::::::::::::::::::::
NP_001 MTLTRWTGMIIGPPRTIYENRIYSLKIECG
10 20 30
100 110 120 130 140 150
pF1KE3 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE
40 50 60 70 80 90
160 170
pF1KE3 NMKLPQPPEGQCYSN
:::::::::::::::
NP_001 NMKLPQPPEGQCYSN
100
>>NP_001269508 (OMIM: 602995) ubiquitin-conjugating enzy (105 aa)
initn: 716 init1: 716 opt: 716 Z-score: 932.4 bits: 178.2 E(85289): 3.4e-45
Smith-Waterman score: 716; 100.0% identity (100.0% similar) in 105 aa overlap (66-170:1-105)
40 50 60 70 80 90
pF1KE3 RNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECG
::::::::::::::::::::::::::::::
NP_001 MTLTRWTGMIIGPPRTIYENRIYSLKIECG
10 20 30
100 110 120 130 140 150
pF1KE3 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKE
40 50 60 70 80 90
160 170
pF1KE3 NMKLPQPPEGQCYSN
:::::::::::::::
NP_001 NMKLPQPPEGQCYSN
100
170 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:11:13 2016 done: Sun Nov 6 05:11:14 2016
Total Scan time: 4.930 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]