Result of FASTA (omim) for
pFN21AE3371
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3371, 1102 aa
1>>>pF1KE3371 1102 - 1102 aa - 1102 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0486+/-0.000453; mu= 17.3987+/- 0.028
mean_var=70.2434+/-13.524, 0's: 0 Z-trim(110.0): 109 B-trim: 15 in 1/55
Lambda= 0.153028
statistics sampled from 18133 (18249) to 18133 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.214), width: 16
Scan time: 13.840
The best scores are: opt bits E(85289)
XP_005250500 (OMIM: 601232) PREDICTED: phosphatidy (1102) 7421 1648.4 0
NP_001269356 (OMIM: 601232) phosphatidylinositol 4 (1102) 7421 1648.4 0
NP_001269355 (OMIM: 601232) phosphatidylinositol 4 (1102) 7421 1648.4 0
NP_002640 (OMIM: 601232) phosphatidylinositol 4,5- (1102) 7421 1648.4 0
XP_011514618 (OMIM: 601232) PREDICTED: phosphatidy (1011) 6806 1512.6 0
XP_016867817 (OMIM: 601232) PREDICTED: phosphatidy (1031) 6806 1512.6 0
XP_011514619 (OMIM: 601232) PREDICTED: phosphatidy ( 884) 5909 1314.6 0
XP_011511196 (OMIM: 114480,114500,114550,162900,16 (1068) 1823 412.5 6.5e-114
NP_006209 (OMIM: 114480,114500,114550,162900,16700 (1068) 1823 412.5 6.5e-114
XP_006713721 (OMIM: 114480,114500,114550,162900,16 (1068) 1823 412.5 6.5e-114
XP_006713722 (OMIM: 602925) PREDICTED: phosphatidy (1070) 1685 382.1 9.7e-105
XP_016862108 (OMIM: 602925) PREDICTED: phosphatidy (1070) 1685 382.1 9.7e-105
XP_011511197 (OMIM: 602925) PREDICTED: phosphatidy (1070) 1685 382.1 9.7e-105
NP_006210 (OMIM: 602925) phosphatidylinositol 4,5- (1070) 1685 382.1 9.7e-105
XP_005247587 (OMIM: 602925) PREDICTED: phosphatidy (1070) 1685 382.1 9.7e-105
XP_016862109 (OMIM: 602925) PREDICTED: phosphatidy ( 674) 1436 327.1 2.2e-88
NP_001242974 (OMIM: 602925) phosphatidylinositol 4 ( 582) 1387 316.2 3.5e-85
XP_016862110 (OMIM: 602925) PREDICTED: phosphatidy ( 657) 1387 316.2 3.9e-85
XP_011511198 (OMIM: 602925) PREDICTED: phosphatidy ( 902) 1387 316.3 5.3e-85
XP_016856972 (OMIM: 602839,615513) PREDICTED: phos (1074) 1353 308.8 1.1e-82
XP_016856974 (OMIM: 602839,615513) PREDICTED: phos (1015) 1339 305.7 9.1e-82
XP_016856973 (OMIM: 602839,615513) PREDICTED: phos (1043) 1339 305.7 9.4e-82
XP_006710750 (OMIM: 602839,615513) PREDICTED: phos (1044) 1339 305.7 9.4e-82
XP_006710752 (OMIM: 602839,615513) PREDICTED: phos (1044) 1339 305.7 9.4e-82
NP_005017 (OMIM: 602839,615513) phosphatidylinosit (1044) 1339 305.7 9.4e-82
XP_016856968 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856969 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856966 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856967 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856971 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856970 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
XP_016856965 (OMIM: 602839,615513) PREDICTED: phos (1103) 1339 305.7 9.9e-82
NP_001308309 (OMIM: 603601) phosphatidylinositol 4 (1306) 923 213.9 5.1e-54
XP_011518488 (OMIM: 603601) PREDICTED: phosphatidy (1630) 923 213.9 6.3e-54
NP_002636 (OMIM: 603601) phosphatidylinositol 4-ph (1686) 923 213.9 6.5e-54
NP_001308307 (OMIM: 603601) phosphatidylinositol 4 (1686) 923 213.9 6.5e-54
XP_016873413 (OMIM: 603601) PREDICTED: phosphatidy (1686) 923 213.9 6.5e-54
XP_016856964 (OMIM: 602838) PREDICTED: phosphatidy (1070) 900 208.8 1.4e-52
XP_005245315 (OMIM: 602838) PREDICTED: phosphatidy (1607) 900 208.8 2.1e-52
XP_011507933 (OMIM: 602838) PREDICTED: phosphatidy (1634) 900 208.8 2.1e-52
XP_016856963 (OMIM: 602838) PREDICTED: phosphatidy (1634) 900 208.8 2.1e-52
NP_002637 (OMIM: 602838) phosphatidylinositol 4-ph (1634) 900 208.8 2.1e-52
XP_011507932 (OMIM: 602838) PREDICTED: phosphatidy (1634) 900 208.8 2.1e-52
XP_016856962 (OMIM: 602838) PREDICTED: phosphatidy (1634) 900 208.8 2.1e-52
XP_005245314 (OMIM: 602838) PREDICTED: phosphatidy (1634) 900 208.8 2.1e-52
XP_016874968 (OMIM: 609001) PREDICTED: phosphatidy ( 817) 852 198.1 1.7e-49
NP_001275703 (OMIM: 609001) phosphatidylinositol 4 (1264) 852 198.2 2.6e-49
XP_016874966 (OMIM: 609001) PREDICTED: phosphatidy (1270) 852 198.2 2.6e-49
XP_016874965 (OMIM: 609001) PREDICTED: phosphatidy (1407) 852 198.2 2.9e-49
XP_016874964 (OMIM: 609001) PREDICTED: phosphatidy (1437) 852 198.2 2.9e-49
>>XP_005250500 (OMIM: 601232) PREDICTED: phosphatidylino (1102 aa)
initn: 7421 init1: 7421 opt: 7421 Z-score: 8845.1 bits: 1648.4 E(85289): 0
Smith-Waterman score: 7421; 100.0% identity (100.0% similar) in 1102 aa overlap (1-1102:1-1102)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE3 TVQFNWFLHLVLGIKQGEKHSA
::::::::::::::::::::::
XP_005 TVQFNWFLHLVLGIKQGEKHSA
1090 1100
>>NP_001269356 (OMIM: 601232) phosphatidylinositol 4,5-b (1102 aa)
initn: 7421 init1: 7421 opt: 7421 Z-score: 8845.1 bits: 1648.4 E(85289): 0
Smith-Waterman score: 7421; 100.0% identity (100.0% similar) in 1102 aa overlap (1-1102:1-1102)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE3 TVQFNWFLHLVLGIKQGEKHSA
::::::::::::::::::::::
NP_001 TVQFNWFLHLVLGIKQGEKHSA
1090 1100
>>NP_001269355 (OMIM: 601232) phosphatidylinositol 4,5-b (1102 aa)
initn: 7421 init1: 7421 opt: 7421 Z-score: 8845.1 bits: 1648.4 E(85289): 0
Smith-Waterman score: 7421; 100.0% identity (100.0% similar) in 1102 aa overlap (1-1102:1-1102)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE3 TVQFNWFLHLVLGIKQGEKHSA
::::::::::::::::::::::
NP_001 TVQFNWFLHLVLGIKQGEKHSA
1090 1100
>>NP_002640 (OMIM: 601232) phosphatidylinositol 4,5-bisp (1102 aa)
initn: 7421 init1: 7421 opt: 7421 Z-score: 8845.1 bits: 1648.4 E(85289): 0
Smith-Waterman score: 7421; 100.0% identity (100.0% similar) in 1102 aa overlap (1-1102:1-1102)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE3 TVQFNWFLHLVLGIKQGEKHSA
::::::::::::::::::::::
NP_002 TVQFNWFLHLVLGIKQGEKHSA
1090 1100
>>XP_011514618 (OMIM: 601232) PREDICTED: phosphatidylino (1011 aa)
initn: 6840 init1: 6806 opt: 6806 Z-score: 8112.0 bits: 1512.6 E(85289): 0
Smith-Waterman score: 6806; 99.9% identity (100.0% similar) in 1011 aa overlap (1-1011:1-1011)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQN
970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
>>XP_016867817 (OMIM: 601232) PREDICTED: phosphatidylino (1031 aa)
initn: 6840 init1: 6806 opt: 6806 Z-score: 8111.8 bits: 1512.6 E(85289): 0
Smith-Waterman score: 6806; 99.9% identity (100.0% similar) in 1011 aa overlap (1-1011:1-1011)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQEKNLNTTALT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
XP_016 YIYAEFPKFTA
1030
>>XP_011514619 (OMIM: 601232) PREDICTED: phosphatidylino (884 aa)
initn: 5909 init1: 5909 opt: 5909 Z-score: 7042.7 bits: 1314.6 E(85289): 0
Smith-Waterman score: 5909; 100.0% identity (100.0% similar) in 876 aa overlap (1-876:1-876)
10 20 30 40 50 60
pF1KE3 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
::::::::::::::::::::::::::::::::::::
XP_011 DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIDGKICHLF
850 860 870 880
910 920 930 940 950 960
pF1KE3 AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
>>XP_011511196 (OMIM: 114480,114500,114550,162900,167000 (1068 aa)
initn: 1583 init1: 617 opt: 1823 Z-score: 2166.1 bits: 412.5 E(85289): 6.5e-114
Smith-Waterman score: 1929; 35.9% identity (65.8% similar) in 997 aa overlap (144-1091:107-1062)
120 130 140 150 160 170
pF1KE3 QVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDEL
..: . ..:.. ::. : . . :.: :.
XP_011 AEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEV
80 90 100 110 120 130
180 190 200 210 220
pF1KE3 EFTRRGLVTPRMAEVASRD---PKLYAMH---PWVTSKP-LPEYLWKKIANNCIFIVI--
. ::.... : :: :. ::. : : :.: ::.....:. .. :..::
XP_011 QDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWV
140 150 160 170 180 190
230 240 250 260 270
pF1KE3 ----HRSTTSQTIKVSPDDTPGAILQSFFTKMAKKKSLMDIPES------QSEQDFVLRV
. . . :.:.. : .: .. . : : .:.. :. . . ..:.:
XP_011 IVSPNNDKQKYTLKINHDCVPEQVIAEAIRK--KTRSMLLSSEQLKLCVLEYQGKYILKV
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE3 CGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTG
:: :::.. . :.......: :. :. ...: : . :. :: . .
XP_011 CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLML------MAKESLYSQLPM--DCFTMPS
260 270 280 290 300
340 350 360 370 380 390
pF1KE3 YHEQLTIHGKDHES-VFTVSLWDCDRKFRVKIR-GIDIPVLPRNTDLTVFVEANIQHGQQ
: .... .. . : ::: . .:.:: . . : :. : ..:...: :: .
XP_011 YSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDID-KIYVRTGIYHGGE
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE3 VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSS
::. .. . . :: ::...: : :::..: : :.: :. . . :.. :
XP_011 PLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSI-CS---VKGRKGAKEEHCP
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE3 ESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
. :...:. :.. :. :...:..: . :: .: .:. .::.::
XP_011 LAWGNINLFDYTDTLV--------SGKMALNLWPVPHGLEDL--LNPIGVTG-SNPNKE-
430 440 450 460
520 530 540 550
pF1KE3 SMSISILLDNYCHPIALP------KHQP---------TPDPEGDRVRAEMPNQLRK----
. . . .: . . .: .: . . : : :.::.
XP_011 TPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKE
470 480 490 500 510 520
560 570 580 590 600 610
pF1KE3 QLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLAR
::.:: . :::. .: ..:..:: :. . :. :::. ::::.... ::. : :
XP_011 QLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCL---
530 540 550 560 570 580
620 630 640 650 660 670
pF1KE3 REVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLES-LEDDDVLHYLLQLVQAVKFEPY
: : . .:.:::::. : ::..::. ::. : :: . .::.::::..:.: :
XP_011 --VKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQY
590 600 610 620 630 640
680 690 700 710 720 730
pF1KE3 HDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDF
:. :.:::::..: :.:::::.:: :.::. ... .:::...::.: :.:: . : .
XP_011 LDNLLVRFLLKKALTNQRIGHFFFWHLKSEM-HNKTVSQRFGLLLESYCRACGMYLKH-L
650 660 670 680 690 700
740 750 760 770 780
pF1KE3 TQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPES---FRVPYDP
..::...: : ..: :: :. :: : ...: :.: .:... .. .. : : .:
XP_011 NRQVEAMEKLINLT-DI--LKQEKKDETQKV--QMKFLVEQMRRPDFMDALQGFLSPLNP
710 720 730 740 750
790 800 810 820 830 840
pF1KE3 GLKAGALAIEKCKVMASKKKPLWLEFKCADP-TALSNETIGIIFKHGDDLRQDMLILQIL
. . : : .:.:..:.: :.::::... : . : .. ::::.::::::::: :::.
XP_011 AHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQII
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 RIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA--FKDEV
::::.::....::: .:::::.: :: .:.::.:... :: .:: . : :: :....
XP_011 RIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKG-GLKGALQFNSHT
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 LNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFG
:..:::.:. : ..::.. :. ::::::::::.::::::::.:::. . :.:::::::
XP_011 LHQWLKDKNKGE-IYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 HILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSP--HFQKFQDICVKAYLALRHHT
:.: . :. .: ..:::::::: :::.:.. .... . .:..::..: :::::.:.:.
XP_011 HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHA
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQF
::.: :::::: .:::.: : .:: ::: .:.. :.:..: .::. :.. . :::...
XP_011 NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKM
1000 1010 1020 1030 1040 1050
1090 1100
pF1KE3 NWFLHLVLGIKQGEKHSA
.:..: .
XP_011 DWIFHTIKQHALN
1060
>>NP_006209 (OMIM: 114480,114500,114550,162900,167000,17 (1068 aa)
initn: 1583 init1: 617 opt: 1823 Z-score: 2166.1 bits: 412.5 E(85289): 6.5e-114
Smith-Waterman score: 1929; 35.9% identity (65.8% similar) in 997 aa overlap (144-1091:107-1062)
120 130 140 150 160 170
pF1KE3 QVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDEL
..: . ..:.. ::. : . . :.: :.
NP_006 AEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEV
80 90 100 110 120 130
180 190 200 210 220
pF1KE3 EFTRRGLVTPRMAEVASRD---PKLYAMH---PWVTSKP-LPEYLWKKIANNCIFIVI--
. ::.... : :: :. ::. : : :.: ::.....:. .. :..::
NP_006 QDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWV
140 150 160 170 180 190
230 240 250 260 270
pF1KE3 ----HRSTTSQTIKVSPDDTPGAILQSFFTKMAKKKSLMDIPES------QSEQDFVLRV
. . . :.:.. : .: .. . : : .:.. :. . . ..:.:
NP_006 IVSPNNDKQKYTLKINHDCVPEQVIAEAIRK--KTRSMLLSSEQLKLCVLEYQGKYILKV
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE3 CGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTG
:: :::.. . :.......: :. :. ...: : . :. :: . .
NP_006 CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLML------MAKESLYSQLPM--DCFTMPS
260 270 280 290 300
340 350 360 370 380 390
pF1KE3 YHEQLTIHGKDHES-VFTVSLWDCDRKFRVKIR-GIDIPVLPRNTDLTVFVEANIQHGQQ
: .... .. . : ::: . .:.:: . . : :. : ..:...: :: .
NP_006 YSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDID-KIYVRTGIYHGGE
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE3 VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSS
::. .. . . :: ::...: : :::..: : :.: :. . . :.. :
NP_006 PLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSI-CS---VKGRKGAKEEHCP
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE3 ESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
. :...:. :.. :. :...:..: . :: .: .:. .::.::
NP_006 LAWGNINLFDYTDTLV--------SGKMALNLWPVPHGLEDL--LNPIGVTG-SNPNKE-
430 440 450 460
520 530 540 550
pF1KE3 SMSISILLDNYCHPIALP------KHQP---------TPDPEGDRVRAEMPNQLRK----
. . . .: . . .: .: . . : : :.::.
NP_006 TPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKE
470 480 490 500 510 520
560 570 580 590 600 610
pF1KE3 QLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLAR
::.:: . :::. .: ..:..:: :. . :. :::. ::::.... ::. : :
NP_006 QLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCL---
530 540 550 560 570 580
620 630 640 650 660 670
pF1KE3 REVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLES-LEDDDVLHYLLQLVQAVKFEPY
: : . .:.:::::. : ::..::. ::. : :: . .::.::::..:.: :
NP_006 --VKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQY
590 600 610 620 630 640
680 690 700 710 720 730
pF1KE3 HDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDF
:. :.:::::..: :.:::::.:: :.::. ... .:::...::.: :.:: . : .
NP_006 LDNLLVRFLLKKALTNQRIGHFFFWHLKSEM-HNKTVSQRFGLLLESYCRACGMYLKH-L
650 660 670 680 690 700
740 750 760 770 780
pF1KE3 TQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPES---FRVPYDP
..::...: : ..: :: :. :: : ...: :.: .:... .. .. : : .:
NP_006 NRQVEAMEKLINLT-DI--LKQEKKDETQKV--QMKFLVEQMRRPDFMDALQGFLSPLNP
710 720 730 740 750
790 800 810 820 830 840
pF1KE3 GLKAGALAIEKCKVMASKKKPLWLEFKCADP-TALSNETIGIIFKHGDDLRQDMLILQIL
. . : : .:.:..:.: :.::::... : . : .. ::::.::::::::: :::.
NP_006 AHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQII
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 RIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA--FKDEV
::::.::....::: .:::::.: :: .:.::.:... :: .:: . : :: :....
NP_006 RIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKG-GLKGALQFNSHT
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 LNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFG
:..:::.:. : ..::.. :. ::::::::::.::::::::.:::. . :.:::::::
NP_006 LHQWLKDKNKGE-IYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 HILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSP--HFQKFQDICVKAYLALRHHT
:.: . :. .: ..:::::::: :::.:.. .... . .:..::..: :::::.:.:.
NP_006 HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHA
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQF
::.: :::::: .:::.: : .:: ::: .:.. :.:..: .::. :.. . :::...
NP_006 NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKM
1000 1010 1020 1030 1040 1050
1090 1100
pF1KE3 NWFLHLVLGIKQGEKHSA
.:..: .
NP_006 DWIFHTIKQHALN
1060
>>XP_006713721 (OMIM: 114480,114500,114550,162900,167000 (1068 aa)
initn: 1583 init1: 617 opt: 1823 Z-score: 2166.1 bits: 412.5 E(85289): 6.5e-114
Smith-Waterman score: 1929; 35.9% identity (65.8% similar) in 997 aa overlap (144-1091:107-1062)
120 130 140 150 160 170
pF1KE3 QVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDEL
..: . ..:.. ::. : . . :.: :.
XP_006 AEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEV
80 90 100 110 120 130
180 190 200 210 220
pF1KE3 EFTRRGLVTPRMAEVASRD---PKLYAMH---PWVTSKP-LPEYLWKKIANNCIFIVI--
. ::.... : :: :. ::. : : :.: ::.....:. .. :..::
XP_006 QDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWV
140 150 160 170 180 190
230 240 250 260 270
pF1KE3 ----HRSTTSQTIKVSPDDTPGAILQSFFTKMAKKKSLMDIPES------QSEQDFVLRV
. . . :.:.. : .: .. . : : .:.. :. . . ..:.:
XP_006 IVSPNNDKQKYTLKINHDCVPEQVIAEAIRK--KTRSMLLSSEQLKLCVLEYQGKYILKV
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE3 CGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTG
:: :::.. . :.......: :. :. ...: : . :. :: . .
XP_006 CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLML------MAKESLYSQLPM--DCFTMPS
260 270 280 290 300
340 350 360 370 380 390
pF1KE3 YHEQLTIHGKDHES-VFTVSLWDCDRKFRVKIR-GIDIPVLPRNTDLTVFVEANIQHGQQ
: .... .. . : ::: . .:.:: . . : :. : ..:...: :: .
XP_006 YSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDID-KIYVRTGIYHGGE
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE3 VLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSS
::. .. . . :: ::...: : :::..: : :.: :. . . :.. :
XP_006 PLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSI-CS---VKGRKGAKEEHCP
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE3 ESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKEN
. :...:. :.. :. :...:..: . :: .: .:. .::.::
XP_006 LAWGNINLFDYTDTLV--------SGKMALNLWPVPHGLEDL--LNPIGVTG-SNPNKE-
430 440 450 460
520 530 540 550
pF1KE3 SMSISILLDNYCHPIALP------KHQP---------TPDPEGDRVRAEMPNQLRK----
. . . .: . . .: .: . . : : :.::.
XP_006 TPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKE
470 480 490 500 510 520
560 570 580 590 600 610
pF1KE3 QLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLAR
::.:: . :::. .: ..:..:: :. . :. :::. ::::.... ::. : :
XP_006 QLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCL---
530 540 550 560 570 580
620 630 640 650 660 670
pF1KE3 REVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLES-LEDDDVLHYLLQLVQAVKFEPY
: : . .:.:::::. : ::..::. ::. : :: . .::.::::..:.: :
XP_006 --VKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQY
590 600 610 620 630 640
680 690 700 710 720 730
pF1KE3 HDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDF
:. :.:::::..: :.:::::.:: :.::. ... .:::...::.: :.:: . : .
XP_006 LDNLLVRFLLKKALTNQRIGHFFFWHLKSEM-HNKTVSQRFGLLLESYCRACGMYLKH-L
650 660 670 680 690 700
740 750 760 770 780
pF1KE3 TQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPES---FRVPYDP
..::...: : ..: :: :. :: : ...: :.: .:... .. .. : : .:
XP_006 NRQVEAMEKLINLT-DI--LKQEKKDETQKV--QMKFLVEQMRRPDFMDALQGFLSPLNP
710 720 730 740 750
790 800 810 820 830 840
pF1KE3 GLKAGALAIEKCKVMASKKKPLWLEFKCADP-TALSNETIGIIFKHGDDLRQDMLILQIL
. . : : .:.:..:.: :.::::... : . : .. ::::.::::::::: :::.
XP_006 AHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQII
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 RIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGA--FKDEV
::::.::....::: .:::::.: :: .:.::.:... :: .:: . : :: :....
XP_006 RIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKG-GLKGALQFNSHT
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 LNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFG
:..:::.:. : ..::.. :. ::::::::::.::::::::.:::. . :.:::::::
XP_006 LHQWLKDKNKGE-IYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 HILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSP--HFQKFQDICVKAYLALRHHT
:.: . :. .: ..:::::::: :::.:.. .... . .:..::..: :::::.:.:.
XP_006 HFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHA
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 NLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQF
::.: :::::: .:::.: : .:: ::: .:.. :.:..: .::. :.. . :::...
XP_006 NLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKM
1000 1010 1020 1030 1040 1050
1090 1100
pF1KE3 NWFLHLVLGIKQGEKHSA
.:..: .
XP_006 DWIFHTIKQHALN
1060
1102 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:56:51 2016 done: Tue Nov 8 10:56:53 2016
Total Scan time: 13.840 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]