Result of FASTA (omim) for
pFN21AE3314
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3314, 855 aa
1>>>pF1KE3314 855 - 855 aa - 855 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6317+/-0.000706; mu= -9.4212+/- 0.042
mean_var=776.3587+/-185.153, 0's: 0 Z-trim(113.0): 772 B-trim: 0 in 0/53
Lambda= 0.046030
statistics sampled from 21302 (22084) to 21302 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.259), width: 16
Scan time: 9.840
The best scores are: opt bits E(85289)
NP_006173 (OMIM: 191311,271665) discoidin domain-c ( 855) 5822 404.3 1.2e-111
XP_006711407 (OMIM: 191311,271665) PREDICTED: disc ( 855) 5822 404.3 1.2e-111
XP_011507888 (OMIM: 191311,271665) PREDICTED: disc ( 855) 5822 404.3 1.2e-111
XP_011507889 (OMIM: 191311,271665) PREDICTED: disc ( 855) 5822 404.3 1.2e-111
NP_001014796 (OMIM: 191311,271665) discoidin domai ( 855) 5822 404.3 1.2e-111
XP_011507890 (OMIM: 191311,271665) PREDICTED: disc ( 559) 3455 246.8 2e-64
NP_001189450 (OMIM: 600408) epithelial discoidin d ( 508) 1369 108.2 9.7e-23
NP_001284581 (OMIM: 600408) epithelial discoidin d ( 876) 1250 100.7 3.1e-20
NP_001945 (OMIM: 600408) epithelial discoidin doma ( 876) 1250 100.7 3.1e-20
NP_001284582 (OMIM: 600408) epithelial discoidin d ( 876) 1250 100.7 3.1e-20
NP_001189452 (OMIM: 600408) epithelial discoidin d ( 894) 1250 100.7 3.1e-20
XP_016866758 (OMIM: 600408) PREDICTED: epithelial ( 882) 1084 89.7 6.5e-17
XP_011513190 (OMIM: 600408) PREDICTED: epithelial ( 900) 1084 89.7 6.6e-17
NP_054699 (OMIM: 600408) epithelial discoidin doma ( 913) 1026 85.9 9.5e-16
NP_001284583 (OMIM: 600408) epithelial discoidin d ( 913) 1026 85.9 9.5e-16
XP_006715248 (OMIM: 600408) PREDICTED: epithelial ( 931) 1026 85.9 9.6e-16
NP_001189451 (OMIM: 600408) epithelial discoidin d ( 767) 908 77.9 2e-13
XP_011513187 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
XP_011513185 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
XP_011513188 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
XP_011513189 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
XP_011513186 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
XP_016866757 (OMIM: 600408) PREDICTED: epithelial ( 919) 908 78.0 2.2e-13
NP_054700 (OMIM: 600408) epithelial discoidin doma ( 919) 908 78.0 2.2e-13
XP_011513184 (OMIM: 600408) PREDICTED: epithelial ( 937) 908 78.0 2.2e-13
XP_016877741 (OMIM: 191316) PREDICTED: NT-3 growth ( 448) 847 73.5 2.5e-12
XP_016877740 (OMIM: 191316) PREDICTED: NT-3 growth ( 456) 847 73.5 2.5e-12
XP_016877734 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 847 73.8 3.2e-12
XP_016877732 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 847 73.8 3.2e-12
XP_016877735 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 847 73.8 3.2e-12
XP_016877733 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 847 73.8 3.2e-12
XP_016877730 (OMIM: 191316) PREDICTED: NT-3 growth ( 763) 847 73.8 3.3e-12
XP_006720607 (OMIM: 191316) PREDICTED: NT-3 growth ( 817) 847 73.9 3.4e-12
NP_001230030 (OMIM: 191316) NT-3 growth factor rec ( 817) 847 73.9 3.4e-12
XP_016877729 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 847 73.9 3.4e-12
XP_006720606 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 847 73.9 3.4e-12
NP_002521 (OMIM: 191316) NT-3 growth factor recept ( 825) 847 73.9 3.4e-12
NP_001007793 (OMIM: 155240,191315,256800) high aff ( 760) 832 72.8 6.5e-12
NP_001012331 (OMIM: 155240,191315,256800) high aff ( 790) 832 72.9 6.7e-12
NP_002520 (OMIM: 155240,191315,256800) high affini ( 796) 832 72.9 6.7e-12
XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 808 71.3 2.1e-11
XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 808 71.3 2.1e-11
NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growt ( 822) 808 71.3 2.1e-11
XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 808 71.3 2.1e-11
XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 808 71.3 2.1e-11
NP_006171 (OMIM: 600456,613886) BDNF/NT-3 growth f ( 838) 808 71.3 2.1e-11
XP_005252060 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 808 71.3 2.1e-11
XP_005252058 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 808 71.3 2.1e-11
XP_016870240 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 808 71.3 2.1e-11
XP_005252061 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 808 71.3 2.1e-11
>>NP_006173 (OMIM: 191311,271665) discoidin domain-conta (855 aa)
initn: 5822 init1: 5822 opt: 5822 Z-score: 2125.2 bits: 404.3 E(85289): 1.2e-111
Smith-Waterman score: 5822; 100.0% identity (100.0% similar) in 855 aa overlap (1-855:1-855)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
790 800 810 820 830 840
850
pF1KE3 SFQEIHLLLLQQGDE
:::::::::::::::
NP_006 SFQEIHLLLLQQGDE
850
>>XP_006711407 (OMIM: 191311,271665) PREDICTED: discoidi (855 aa)
initn: 5822 init1: 5822 opt: 5822 Z-score: 2125.2 bits: 404.3 E(85289): 1.2e-111
Smith-Waterman score: 5822; 100.0% identity (100.0% similar) in 855 aa overlap (1-855:1-855)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
790 800 810 820 830 840
850
pF1KE3 SFQEIHLLLLQQGDE
:::::::::::::::
XP_006 SFQEIHLLLLQQGDE
850
>>XP_011507888 (OMIM: 191311,271665) PREDICTED: discoidi (855 aa)
initn: 5822 init1: 5822 opt: 5822 Z-score: 2125.2 bits: 404.3 E(85289): 1.2e-111
Smith-Waterman score: 5822; 100.0% identity (100.0% similar) in 855 aa overlap (1-855:1-855)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
790 800 810 820 830 840
850
pF1KE3 SFQEIHLLLLQQGDE
:::::::::::::::
XP_011 SFQEIHLLLLQQGDE
850
>>XP_011507889 (OMIM: 191311,271665) PREDICTED: discoidi (855 aa)
initn: 5822 init1: 5822 opt: 5822 Z-score: 2125.2 bits: 404.3 E(85289): 1.2e-111
Smith-Waterman score: 5822; 100.0% identity (100.0% similar) in 855 aa overlap (1-855:1-855)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
790 800 810 820 830 840
850
pF1KE3 SFQEIHLLLLQQGDE
:::::::::::::::
XP_011 SFQEIHLLLLQQGDE
850
>>NP_001014796 (OMIM: 191311,271665) discoidin domain-co (855 aa)
initn: 5822 init1: 5822 opt: 5822 Z-score: 2125.2 bits: 404.3 E(85289): 1.2e-111
Smith-Waterman score: 5822; 100.0% identity (100.0% similar) in 855 aa overlap (1-855:1-855)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
790 800 810 820 830 840
850
pF1KE3 SFQEIHLLLLQQGDE
:::::::::::::::
NP_001 SFQEIHLLLLQQGDE
850
>>XP_011507890 (OMIM: 191311,271665) PREDICTED: discoidi (559 aa)
initn: 3449 init1: 3449 opt: 3455 Z-score: 1277.5 bits: 246.8 E(85289): 2e-64
Smith-Waterman score: 3455; 98.1% identity (98.6% similar) in 516 aa overlap (1-516:1-516)
10 20 30 40 50 60
pF1KE3 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
:::::::::::::::::::::: . :: :. :.
XP_011 YQEPSRLIRKLPEFAPGEEESGEDDVVGRVSREKPQQASDLVCRCSWPNLSNSPLLLNIR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
XP_011 CVEGPTYQKRKKKIIKHVN
550
>>NP_001189450 (OMIM: 600408) epithelial discoidin domai (508 aa)
initn: 1475 init1: 543 opt: 1369 Z-score: 529.2 bits: 108.2 E(85289): 9.7e-23
Smith-Waterman score: 1588; 48.6% identity (70.7% similar) in 516 aa overlap (5-496:3-498)
10 20 30 40 50
pF1KE3 MILIPRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTA
:. : :.::: . :. :.. .:: ::: :::. ::: ::.:::.::.:::
NP_001 MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 AKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPM
:...::.: .::::::: : : . .:.::.::. ::...::::::::::: : ::.
NP_001 ARHSRLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 YKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVC
:.. ::::: ::..:..: :..:..:: .: . :::: ::.:::.::: : .:. :.::
NP_001 YRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 MRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGV
.:::::::.: :::.::.::.:: . : . .:::::.::: .:: . :::::.:::
NP_001 LRVELYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGV
::::: ...: .:::::::::: :.: ..::.:. :::::.: : .:.:::::: . :.
NP_001 VGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KIFKEVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADT
.. :.: :: . : :: . . : . .: :: :.::: :.: ..:.. ::
NP_001 RLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGP
300 310 320 330 340 350
360 370 380 390
pF1KE3 WMMFSEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDS
:..::::.: ::. . :.: :: : .: . : .:. :.. :
NP_001 WLLFSEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 NTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNN
: ::::::::::..:: ::...::: :...: :: ::.:..:.:: ::.:.:. ..::
NP_001 PTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE3 NRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPE
.: : : : :::: : . :. ::
NP_001 --RPGPRE-----------P--PPYQEP-RPRGNPPHSAPCVPNGSGAPV
480 490 500
520 530 540 550 560 570
pF1KE3 GVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGE
>>NP_001284581 (OMIM: 600408) epithelial discoidin domai (876 aa)
initn: 3015 init1: 887 opt: 1250 Z-score: 484.3 bits: 100.7 E(85289): 3.1e-20
Smith-Waterman score: 3152; 54.8% identity (75.8% similar) in 887 aa overlap (5-849:3-868)
10 20 30 40 50
pF1KE3 MILIPRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTA
:. : :.::: . :. :.. .:: ::: :::. ::: ::.:::.::.:::
NP_001 MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 AKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPM
:...::.: .::::::: : : . .:.::.::. ::...::::::::::: : ::.
NP_001 ARHSRLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 YKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVC
:.. ::::: ::..:..: :..:..:: .: . :::: ::.:::.::: : .:. :.::
NP_001 YRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 MRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGV
.:::::::.: :::.::.::.:: . : . .:::::.::: .:: . :::::.:::
NP_001 LRVELYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGV
::::: ...: .:::::::::: :.: ..::.:. :::::.: : .:.:::::: . :.
NP_001 VGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KIFKEVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADT
.. :.: :: . : :: . . : . .: :: :.::: :.: ..:.. ::
NP_001 RLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGP
300 310 320 330 340 350
360 370 380 390
pF1KE3 WMMFSEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDS
:..::::.: ::. . :.: :: : .: . : .:. :.. :
NP_001 WLLFSEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 NTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNN
: ::::::::::..:: ::...::: :...: :: ::.:..:.:: ::.:.:. ..::
NP_001 PTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE3 NRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEE-SGCSG-VVKPVQPSG
.: : : : :::: : . :. :: . :. :: ..: .:..
NP_001 --RPGPRE-----------P--PPYQEP-RPRGNPPHSAPCVPNGSAYSGDYMEPEKPGA
480 490 500 510
520 530 540 550 560
pF1KE3 P-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKE
: ..::::::::::.::::::::::.:::. . : .:::. : :::
NP_001 PLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAV-GDGPPRVDFPRSRLRFKE
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE3 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK
:::::::::::::::.. . . . :: :.: ..:.:::::.:: ::.::::::::::.:
NP_001 KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVK
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 IMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE---------PPNSSSSD
:::::::::::.::.::. ::::::::.:::::::::::: :. : ......
NP_001 IMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQ
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 VRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG
:.:: : .:.::::::.::..::::::::::::::::.:.::::::::::::::.:
NP_001 GPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAG
700 710 720 730 740 750
740 750 760 770 780 790
pF1KE3 DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVI
::::.:::::::::::.:: ::.::::::::::::::::::.. .:. ::..::.:::::
NP_001 DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVI
760 770 780 790 800 810
800 810 820 830 840 850
pF1KE3 ENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE
::.::::::::::.:: .: ::...:.::: :: :....:: :...: .:
NP_001 ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV
820 830 840 850 860 870
>>NP_001945 (OMIM: 600408) epithelial discoidin domain-c (876 aa)
initn: 3015 init1: 887 opt: 1250 Z-score: 484.3 bits: 100.7 E(85289): 3.1e-20
Smith-Waterman score: 3152; 54.8% identity (75.8% similar) in 887 aa overlap (5-849:3-868)
10 20 30 40 50
pF1KE3 MILIPRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTA
:. : :.::: . :. :.. .:: ::: :::. ::: ::.:::.::.:::
NP_001 MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 AKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPM
:...::.: .::::::: : : . .:.::.::. ::...::::::::::: : ::.
NP_001 ARHSRLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 YKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVC
:.. ::::: ::..:..: :..:..:: .: . :::: ::.:::.::: : .:. :.::
NP_001 YRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 MRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGV
.:::::::.: :::.::.::.:: . : . .:::::.::: .:: . :::::.:::
NP_001 LRVELYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGV
::::: ...: .:::::::::: :.: ..::.:. :::::.: : .:.:::::: . :.
NP_001 VGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KIFKEVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADT
.. :.: :: . : :: . . : . .: :: :.::: :.: ..:.. ::
NP_001 RLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGP
300 310 320 330 340 350
360 370 380 390
pF1KE3 WMMFSEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDS
:..::::.: ::. . :.: :: : .: . : .:. :.. :
NP_001 WLLFSEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 NTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNN
: ::::::::::..:: ::...::: :...: :: ::.:..:.:: ::.:.:. ..::
NP_001 PTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE3 NRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEE-SGCSG-VVKPVQPSG
.: : : : :::: : . :. :: . :. :: ..: .:..
NP_001 --RPGPRE-----------P--PPYQEP-RPRGNPPHSAPCVPNGSAYSGDYMEPEKPGA
480 490 500 510
520 530 540 550 560
pF1KE3 P-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKE
: ..::::::::::.::::::::::.:::. . : .:::. : :::
NP_001 PLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAV-GDGPPRVDFPRSRLRFKE
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE3 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK
:::::::::::::::.. . . . :: :.: ..:.:::::.:: ::.::::::::::.:
NP_001 KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVK
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 IMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE---------PPNSSSSD
:::::::::::.::.::. ::::::::.:::::::::::: :. : ......
NP_001 IMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQ
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 VRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG
:.:: : .:.::::::.::..::::::::::::::::.:.::::::::::::::.:
NP_001 GPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAG
700 710 720 730 740 750
740 750 760 770 780 790
pF1KE3 DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVI
::::.:::::::::::.:: ::.::::::::::::::::::.. .:. ::..::.:::::
NP_001 DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVI
760 770 780 790 800 810
800 810 820 830 840 850
pF1KE3 ENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE
::.::::::::::.:: .: ::...:.::: :: :....:: :...: .:
NP_001 ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV
820 830 840 850 860 870
>>NP_001284582 (OMIM: 600408) epithelial discoidin domai (876 aa)
initn: 3015 init1: 887 opt: 1250 Z-score: 484.3 bits: 100.7 E(85289): 3.1e-20
Smith-Waterman score: 3152; 54.8% identity (75.8% similar) in 887 aa overlap (5-849:3-868)
10 20 30 40 50
pF1KE3 MILIPRMLLVLFLLLPILSS---AKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTA
:. : :.::: . :. :.. .:: ::: :::. ::: ::.:::.::.:::
NP_001 MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 AKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPM
:...::.: .::::::: : : . .:.::.::. ::...::::::::::: : ::.
NP_001 ARHSRLESSDGDGAWCPAGSVFPKE-EEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 YKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVC
:.. ::::: ::..:..: :..:..:: .: . :::: ::.:::.::: : .:. :.::
NP_001 YRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 MRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDG-AVGYSMTEGLGQLTDGV
.:::::::.: :::.::.::.:: . : . .:::::.::: .:: . :::::.:::
NP_001 LRVELYGCLWRDGLLSYTAPVGQTMYL--SEAVYLNDSTYDGHTVGGLQYGGLGQLADGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGV
::::: ...: .:::::::::: :.: ..::.:. :::::.: : .:.:::::: . :.
NP_001 VGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 KIFKEVQCYFR-SEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADT
.. :.: :: . : :: . . : . .: :: :.::: :.: ..:.. ::
NP_001 RLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGP
300 310 320 330 340 350
360 370 380 390
pF1KE3 WMMFSEITFQSDAAMYNNSEAL----PTSP---------------MAPTTYDPMLKVDDS
:..::::.: ::. . :.: :: : .: . : .:. :.. :
NP_001 WLLFSEISFISDV-VNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE3 NTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNN
: ::::::::::..:: ::...::: :...: :: ::.:..:.:: ::.:.:. ..::
NP_001 PTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE3 NRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEE-SGCSG-VVKPVQPSG
.: : : : :::: : . :. :: . :. :: ..: .:..
NP_001 --RPGPRE-----------P--PPYQEP-RPRGNPPHSAPCVPNGSAYSGDYMEPEKPGA
480 490 500 510
520 530 540 550 560
pF1KE3 P-------EGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKE
: ..::::::::::.::::::::::.:::. . : .:::. : :::
NP_001 PLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAV-GDGPPRVDFPRSRLRFKE
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE3 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK
:::::::::::::::.. . . . :: :.: ..:.:::::.:: ::.::::::::::.:
NP_001 KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVK
580 590 600 610 620 630
630 640 650 660 670
pF1KE3 IMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHE---------PPNSSSSD
:::::::::::.::.::. ::::::::.:::::::::::: :. : ......
NP_001 IMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQ
640 650 660 670 680 690
680 690 700 710 720 730
pF1KE3 VRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG
:.:: : .:.::::::.::..::::::::::::::::.:.::::::::::::::.:
NP_001 GPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAG
700 710 720 730 740 750
740 750 760 770 780 790
pF1KE3 DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVI
::::.:::::::::::.:: ::.::::::::::::::::::.. .:. ::..::.:::::
NP_001 DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVI
760 770 780 790 800 810
800 810 820 830 840 850
pF1KE3 ENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLLLQQGDE
::.::::::::::.:: .: ::...:.::: :: :....:: :...: .:
NP_001 ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTV
820 830 840 850 860 870
855 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:13:33 2016 done: Tue Nov 8 02:13:35 2016
Total Scan time: 9.840 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]