Result of FASTA (ccds) for
pFN21AE3287
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3287, 740 aa
1>>>pF1KE3287 740 - 740 aa - 740 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1802+/-0.00109; mu= 17.0492+/- 0.066
mean_var=118.1419+/-23.716, 0's: 0 Z-trim(106.1): 82 B-trim: 0 in 0/50
Lambda= 0.117997
statistics sampled from 8734 (8806) to 8734 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.271), width: 16
Scan time: 3.580
The best scores are: opt bits E(32554)
CCDS3015.1 DTX3L gene_id:151636|Hs108|chr3 ( 740) 4918 849.1 0
CCDS41800.1 DTX3 gene_id:196403|Hs108|chr12 ( 347) 751 139.5 8.6e-33
CCDS66410.1 DTX3 gene_id:196403|Hs108|chr12 ( 350) 751 139.5 8.7e-33
CCDS43605.1 DTX2 gene_id:113878|Hs108|chr7 ( 575) 521 100.5 7.6e-21
CCDS5587.1 DTX2 gene_id:113878|Hs108|chr7 ( 622) 521 100.6 8.1e-21
CCDS76408.1 DTX4 gene_id:23220|Hs108|chr11 ( 513) 508 98.3 3.2e-20
CCDS44612.1 DTX4 gene_id:23220|Hs108|chr11 ( 619) 508 98.3 3.7e-20
CCDS9164.1 DTX1 gene_id:1840|Hs108|chr12 ( 620) 498 96.6 1.2e-19
>>CCDS3015.1 DTX3L gene_id:151636|Hs108|chr3 (740 aa)
initn: 4918 init1: 4918 opt: 4918 Z-score: 4531.6 bits: 849.1 E(32554): 0
Smith-Waterman score: 4918; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740)
10 20 30 40 50 60
pF1KE3 MASHLRPPSPLLVRVYKSGPRVRRKLESYFQSSKSSGGGECTVSTQEHEAPGTFRVEFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MASHLRPPSPLLVRVYKSGPRVRRKLESYFQSSKSSGGGECTVSTQEHEAPGTFRVEFSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RAAKERVLKKGEHQILVDEKPVPIFLVPTENSIKKNTRPQISSLTQSQAETPSGDMHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 RAAKERVLKKGEHQILVDEKPVPIFLVPTENSIKKNTRPQISSLTQSQAETPSGDMHQHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GHIPNAVDSCLQKIFLTVTADLNCNLFSKEQRAYITTLCPSIRKMEGHDGIEKVCGDFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GHIPNAVDSCLQKIFLTVTADLNCNLFSKEQRAYITTLCPSIRKMEGHDGIEKVCGDFQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IERIHQFLSEQFLESEQKQQFSPSMTERKPLSQQERDSCISPSEPETKAEQKSNYFEVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 IERIHQFLSEQFLESEQKQQFSPSMTERKPLSQQERDSCISPSEPETKAEQKSNYFEVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 PYFEYFKYICPDKINSIEKRFGVNIEIQESSPNMVCLDFTSSRSGDLEAARESFASEFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PYFEYFKYICPDKINSIEKRFGVNIEIQESSPNMVCLDFTSSRSGDLEAARESFASEFQK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NTEPLKQECVSLADSKQANKFKQELNHQFTKLLIKEKGGELTLLGTQDDISAAKQKISEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 NTEPLKQECVSLADSKQANKFKQELNHQFTKLLIKEKGGELTLLGTQDDISAAKQKISEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FVKIPVKLFAANYMMNVIEVDSAHYKLLETELLQEISEIEKRYDICSKVSEKGQKTCILF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FVKIPVKLFAANYMMNVIEVDSAHYKLLETELLQEISEIEKRYDICSKVSEKGQKTCILF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ESKDRQVDLSVHAYASFIDAFQHASCQLMREVLLLKSLGKERKHLHQTKFADDFRKRHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 ESKDRQVDLSVHAYASFIDAFQHASCQLMREVLLLKSLGKERKHLHQTKFADDFRKRHPN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKKLKEGHETPMDIDSDDSKAASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKKLKEGHETPMDIDSDDSKAASP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PLKGSVSSEASELDKKEKGICVICMDTISNKKVLPKCKHEFCAPCINKAMSYKPICPTCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 PLKGSVSSEASELDKKEKGICVICMDTISNKKVLPKCKHEFCAPCINKAMSYKPICPTCQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TSYGIQKGNQPEGSMVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYPGIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 TSYGIQKGNQPEGSMVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYPGIQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 TAYLPDNKEGRKVLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 TAYLPDNKEGRKVLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYG
670 680 690 700 710 720
730 740
pF1KE3 YPDPSYLKRVKEELKAKGIE
::::::::::::::::::::
CCDS30 YPDPSYLKRVKEELKAKGIE
730 740
>>CCDS41800.1 DTX3 gene_id:196403|Hs108|chr12 (347 aa)
initn: 742 init1: 532 opt: 751 Z-score: 702.2 bits: 139.5 E(32554): 8.6e-33
Smith-Waterman score: 751; 53.4% identity (71.6% similar) in 204 aa overlap (540-739:143-344)
510 520 530 540 550 560
pF1KE3 GGMSSLAGKKLKEGHETPMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTIS
::: . . : ..... : ::. :.
CCDS41 EHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQ
120 130 140 150 160 170
570 580 590 600 610 620
pF1KE3 NKKVLPKCKHEFCAPCINKAMSYKPICPTCQTSYGIQKGNQPE-GSMVFTVSRDS---LP
: :.: ::.: :: ::..:.. : :: : :: ::::. : :. ::.:. ::
CCDS41 NAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRML--VSKDATLLLP
180 190 200 210 220 230
630 640 650 660 670 680
pF1KE3 GYESFGTIVITYSMKAGIQTEEHPNPGKRYPGIQRTAYLPDNKEGRKVLKLLYRAFDQKL
.::..::::: : . :.: :::::: :::: :.::::: :: ::: :. .::::.:
CCDS41 SYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRL
240 250 260 270 280 290
690 700 710 720 730 740
pF1KE3 IFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYGYPDPSYLKRVKEELKAKGIE
::.: : . : .:::::::::::: :::...:::::.:: ::.:::.::::
CCDS41 TFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD
300 310 320 330 340
>>CCDS66410.1 DTX3 gene_id:196403|Hs108|chr12 (350 aa)
initn: 742 init1: 532 opt: 751 Z-score: 702.1 bits: 139.5 E(32554): 8.7e-33
Smith-Waterman score: 751; 53.4% identity (71.6% similar) in 204 aa overlap (540-739:146-347)
510 520 530 540 550 560
pF1KE3 GGMSSLAGKKLKEGHETPMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTIS
::: . . : ..... : ::. :.
CCDS66 EHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQ
120 130 140 150 160 170
570 580 590 600 610 620
pF1KE3 NKKVLPKCKHEFCAPCINKAMSYKPICPTCQTSYGIQKGNQPE-GSMVFTVSRDS---LP
: :.: ::.: :: ::..:.. : :: : :: ::::. : :. ::.:. ::
CCDS66 NAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRML--VSKDATLLLP
180 190 200 210 220 230
630 640 650 660 670 680
pF1KE3 GYESFGTIVITYSMKAGIQTEEHPNPGKRYPGIQRTAYLPDNKEGRKVLKLLYRAFDQKL
.::..::::: : . :.: :::::: :::: :.::::: :: ::: :. .::::.:
CCDS66 SYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRL
240 250 260 270 280 290
690 700 710 720 730 740
pF1KE3 IFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYGYPDPSYLKRVKEELKAKGIE
::.: : . : .:::::::::::: :::...:::::.:: ::.:::.::::
CCDS66 TFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD
300 310 320 330 340 350
>>CCDS43605.1 DTX2 gene_id:113878|Hs108|chr7 (575 aa)
initn: 560 init1: 274 opt: 521 Z-score: 487.7 bits: 100.5 E(32554): 7.6e-21
Smith-Waterman score: 528; 41.2% identity (60.6% similar) in 226 aa overlap (540-739:344-567)
510 520 530 540 550 560
pF1KE3 GGMSSLAGKKLKEGHETPMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTIS
: . ... . :: :.:::. .:
CCDS43 PGSVPATVPMQMPKPSRVQQALAGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLS
320 330 340 350 360 370
570 580 590 600
pF1KE3 ----------NKKV-------LPKCKHEFCAPCI-------NKAMSYKPICPTCQTSYGI
.: . : ::.: : :. :: : . ::.:.: ::
CCDS43 TASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQ--CPSCKTIYGE
380 390 400 410 420 430
610 620 630 640 650 660
pF1KE3 QKGNQPEGSMVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAY
. :.::.:.: . ::::.:. :::.:.::. ::: ::::::: . :. : :
CCDS43 KTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCY
440 450 460 470 480 490
670 680 690 700 710 720
pF1KE3 LPDNKEGRKVLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYGYPD
:::: .:::::.:: :. ..:::::: : . : .:...::.::::: . .::::
CCDS43 LPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPD
500 510 520 530 540 550
730 740
pF1KE3 PSYLKRVKEELKAKGIE
:.::. : :: :.:.
CCDS43 PNYLQNVLAELAAQGVTEDCLEQQ
560 570
>>CCDS5587.1 DTX2 gene_id:113878|Hs108|chr7 (622 aa)
initn: 560 init1: 274 opt: 521 Z-score: 487.3 bits: 100.6 E(32554): 8.1e-21
Smith-Waterman score: 546; 38.3% identity (58.5% similar) in 277 aa overlap (490-739:343-614)
460 470 480 490 500 510
pF1KE3 KERKHLHQTKFADDFRKRHPNVHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKK
:. ::: :..: : . . : ::.:.
CCDS55 SPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKS
320 330 340 350 360 370
520 530 540 550 560
pF1KE3 LKEGHET-PMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTIS---------
.. :.. . : : . ... . :: :.:::. .:
CCDS55 HGSVKRLRKMSVKGATPKPEPEPEQ-VIKNYTEELKVPPDEDCIICMEKLSTASGYSDVT
380 390 400 410 420
570 580 590 600 610
pF1KE3 -NKKV-------LPKCKHEFCAPCI-------NKAMSYKPICPTCQTSYGIQKGNQPEGS
.: . : ::.: : :. :: : . ::.:.: :: . :.::.:.
CCDS55 DSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQ--CPSCKTIYGEKTGTQPQGK
430 440 450 460 470 480
620 630 640 650 660 670
pF1KE3 MVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAYLPDNKEGRK
: . ::::.:. :::.:.::. ::: ::::::: . :. : ::::: .:::
CCDS55 MEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRK
490 500 510 520 530 540
680 690 700 710 720 730
pF1KE3 VLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEMYGYPDPSYLKRVKE
::.:: :. ..:::::: : . : .:...::.::::: . .:::::.::. :
CCDS55 VLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLA
550 560 570 580 590 600
740
pF1KE3 ELKAKGIE
:: :.:.
CCDS55 ELAAQGVTEDCLEQQ
610 620
>>CCDS76408.1 DTX4 gene_id:23220|Hs108|chr11 (513 aa)
initn: 489 init1: 279 opt: 508 Z-score: 476.4 bits: 98.3 E(32554): 3.2e-20
Smith-Waterman score: 518; 36.0% identity (58.9% similar) in 275 aa overlap (490-739:233-503)
460 470 480 490 500 510
pF1KE3 KERKHLHQTKFADDFRKRHPNVHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKK
:. .::: :.. . ::. .:. :.
CCDS76 IASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKS
210 220 230 240 250 260
520 530 540 550 560 570
pF1KE3 LKEGHETPMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTISNKK-------
. .: . ..: .. : . ... ... . :.:::. .. .
CCDS76 IPGVSNTSRKTTKKQAKKGKTPEE-VLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQP
270 280 290 300 310 320
580 590 600 610
pF1KE3 -VLP-------KCKHEFCAPCI-------NKAMSYKPICPTCQTSYGIQKGNQPEGSMVF
: : .: : . :. :: : . ::::.: ::.. :.:: :.: .
CCDS76 TVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQ--CPTCKTIYGVKTGTQPPGKMEY
330 340 350 360 370
620 630 640 650 660 670
pF1KE3 TVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAYLPDNKEGRKVLK
. ::::. . :: : ::. ::: ::::::: . :. : ::::...::::::
CCDS76 HLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLK
380 390 400 410 420 430
680 690 700 710 720 730
pF1KE3 LLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEM-YGYPDPSYLKRVKEEL
:: :.:..:::..: : . : ::.. ::..:::: .::. .:::: .:: : ::
CCDS76 LLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKT-EFGSNLTGHGYPDANYLDNVLAEL
440 450 460 470 480 490
740
pF1KE3 KAKGIE
:.::
CCDS76 AAQGISEDSTAQEKD
500 510
>>CCDS44612.1 DTX4 gene_id:23220|Hs108|chr11 (619 aa)
initn: 489 init1: 279 opt: 508 Z-score: 475.3 bits: 98.3 E(32554): 3.7e-20
Smith-Waterman score: 518; 36.0% identity (58.9% similar) in 275 aa overlap (490-739:339-609)
460 470 480 490 500 510
pF1KE3 KERKHLHQTKFADDFRKRHPNVHFVLNQESMTLTGLPNHLAKAKQYVLKGGGMSSLAGKK
:. .::: :.. . ::. .:. :.
CCDS44 IASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKS
310 320 330 340 350 360
520 530 540 550 560 570
pF1KE3 LKEGHETPMDIDSDDSKAASPPLKGSVSSEASELDKKEKGICVICMDTISNKK-------
. .: . ..: .. : . ... ... . :.:::. .. .
CCDS44 IPGVSNTSRKTTKKQAKKGKTPEE-VLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQP
370 380 390 400 410 420
580 590 600 610
pF1KE3 -VLP-------KCKHEFCAPCI-------NKAMSYKPICPTCQTSYGIQKGNQPEGSMVF
: : .: : . :. :: : . ::::.: ::.. :.:: :.: .
CCDS44 TVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQ--CPTCKTIYGVKTGTQPPGKMEY
430 440 450 460 470 480
620 630 640 650 660 670
pF1KE3 TVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAYLPDNKEGRKVLK
. ::::. . :: : ::. ::: ::::::: . :. : ::::...::::::
CCDS44 HLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLK
490 500 510 520 530 540
680 690 700 710 720 730
pF1KE3 LLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEM-YGYPDPSYLKRVKEEL
:: :.:..:::..: : . : ::.. ::..:::: .::. .:::: .:: : ::
CCDS44 LLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKT-EFGSNLTGHGYPDANYLDNVLAEL
550 560 570 580 590 600
740
pF1KE3 KAKGIE
:.::
CCDS44 AAQGISEDSTAQEKD
610
>>CCDS9164.1 DTX1 gene_id:1840|Hs108|chr12 (620 aa)
initn: 475 init1: 271 opt: 498 Z-score: 466.1 bits: 96.6 E(32554): 1.2e-19
Smith-Waterman score: 499; 42.2% identity (63.1% similar) in 206 aa overlap (561-739:411-613)
540 550 560 570
pF1KE3 DSDDSKAASPPLKGSVSSEASELDKKEKGICVICMD----------TISNKKVLP-----
:.:::. .. .: : :
CCDS91 TKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGR
390 400 410 420 430 440
580 590 600 610 620
pF1KE3 --KCKHEFCAPCI-------NKAMSYKPICPTCQTSYGIQKGNQPEGSMVFTVSRDSLPG
.: : . :. :: : . ::::.. :: . :.:: :.: : . ::::
CCDS91 LGRCGHMYHLLCLVAMYSNGNKDGSLQ--CPTCKAIYGEKTGTQPPGKMEFHLIPHSLPG
450 460 470 480 490
630 640 650 660 670 680
pF1KE3 YESFGTIVITYSMKAGIQTEEHPNPGKRYP--GIQRTAYLPDNKEGRKVLKLLYRAFDQK
. . :: :.:.. .::: :::::::.. :. : :::.:..:::::.:: :....
CCDS91 FPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERR
500 510 520 530 540 550
690 700 710 720 730 740
pF1KE3 LIFTVGYSRVLGVSDVITWNDIHHKTSRFGGPEM-YGYPDPSYLKRVKEELKAKGIE
::::.: : . : ::...::.::::: .::. .:::: ::: : :: :.:.
CCDS91 LIFTIGTSNTTGESDTVVWNEIHHKT-EFGSNLTGHGYPDASYLDNVLAELTAQGVSEAA
560 570 580 590 600 610
CCDS91 AKA
620
740 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:42:32 2016 done: Sun Nov 6 17:42:33 2016
Total Scan time: 3.580 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]