Result of FASTA (omim) for
pFN21AE3277
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3277, 692 aa
1>>>pF1KE3277 692 - 692 aa - 692 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5037+/-0.000573; mu= 5.4992+/- 0.035
mean_var=493.9756+/-108.596, 0's: 0 Z-trim(117.2): 2082 B-trim: 12 in 1/51
Lambda= 0.057706
statistics sampled from 26391 (29052) to 26391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.341), width: 16
Scan time: 10.940
The best scores are: opt bits E(85289)
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692) 4636 402.1 3.6e-111
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716) 4535 393.7 1.3e-108
XP_016879989 (OMIM: 609799,613824,615415) PREDICTE ( 666) 2833 252.0 5.5e-66
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705) 2833 252.0 5.6e-66
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729) 2833 252.1 5.7e-66
XP_016879990 (OMIM: 609799,613824,615415) PREDICTE ( 484) 1706 157.9 8.2e-38
NP_001316166 (OMIM: 609798,614262,617022,617025) s ( 991) 1026 101.8 1.3e-20
XP_005268266 (OMIM: 609798,614262,617022,617025) P ( 873) 837 86.0 6.6e-16
XP_011533370 (OMIM: 616731) PREDICTED: serine/thre ( 483) 814 83.7 1.9e-15
XP_006719871 (OMIM: 616731) PREDICTED: serine/thre ( 598) 814 83.8 2.1e-15
XP_011533368 (OMIM: 616731) PREDICTED: serine/thre ( 697) 814 83.9 2.2e-15
NP_954983 (OMIM: 616731) serine/threonine-protein ( 708) 814 84.0 2.2e-15
XP_016876045 (OMIM: 616731) PREDICTED: serine/thre ( 737) 814 84.0 2.3e-15
XP_016876044 (OMIM: 616731) PREDICTED: serine/thre ( 755) 814 84.0 2.3e-15
XP_016876046 (OMIM: 616731) PREDICTED: serine/thre ( 780) 814 84.0 2.3e-15
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 808 83.5 3.2e-15
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 808 83.8 4.1e-15
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 808 83.8 4.1e-15
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 808 83.8 4.1e-15
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 808 83.9 4.1e-15
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 808 83.9 4.2e-15
NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 808 83.9 4.2e-15
XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 808 83.9 4.2e-15
NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 808 83.9 4.2e-15
XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 752 78.8 7.8e-14
XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 752 78.9 8.5e-14
XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 752 78.9 8.6e-14
NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 752 78.9 8.7e-14
XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 752 78.9 8.7e-14
XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 752 78.9 8.8e-14
NP_149107 (OMIM: 609798,614262,617022,617025) seri ( 979) 717 76.1 7.1e-13
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 631 68.4 7.2e-11
NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 631 68.5 7.3e-11
NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 631 68.5 7.3e-11
NP_598001 (OMIM: 606848) serine/threonine-protein ( 302) 597 65.3 4e-10
NP_001159640 (OMIM: 604884) serine/threonine-prote ( 313) 592 64.9 5.5e-10
XP_005251721 (OMIM: 604884) PREDICTED: serine/thre ( 313) 592 64.9 5.5e-10
NP_001159642 (OMIM: 604884) serine/threonine-prote ( 313) 592 64.9 5.5e-10
XP_006716999 (OMIM: 604884) PREDICTED: serine/thre ( 313) 592 64.9 5.5e-10
NP_055212 (OMIM: 604884) serine/threonine-protein ( 313) 592 64.9 5.5e-10
NP_001159639 (OMIM: 604884) serine/threonine-prote ( 331) 592 64.9 5.6e-10
NP_001159641 (OMIM: 604884) serine/threonine-prote ( 338) 592 64.9 5.7e-10
NP_001159643 (OMIM: 604884) serine/threonine-prote ( 347) 592 64.9 5.8e-10
XP_016869706 (OMIM: 604884) PREDICTED: serine/thre ( 347) 592 64.9 5.8e-10
NP_001138473 (OMIM: 604884) serine/threonine-prote ( 347) 592 64.9 5.8e-10
NP_665917 (OMIM: 609779) serine/threonine-protein ( 470) 579 64.1 1.4e-09
NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482) 579 64.1 1.4e-09
XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563) 579 64.2 1.5e-09
XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563) 579 64.2 1.5e-09
XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599) 579 64.3 1.6e-09
>>NP_835464 (OMIM: 609799,613824,615415) serine/threonin (692 aa)
initn: 4636 init1: 4636 opt: 4636 Z-score: 2116.8 bits: 402.1 E(85289): 3.6e-111
Smith-Waterman score: 4636; 100.0% identity (100.0% similar) in 692 aa overlap (1-692:1-692)
10 20 30 40 50 60
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 THLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 THLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPSNTGSRTTSVRCRGIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 LEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPSNTGSRTTSVRCRGIPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 GPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 LGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 GCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 GCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 ESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 ESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 HQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 HQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_835 SRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQL
610 620 630 640 650 660
670 680 690
pF1KE3 DETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
::::::::::::::::::::::::::::::::
NP_835 DETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
670 680 690
>>XP_011522942 (OMIM: 609799,613824,615415) PREDICTED: s (716 aa)
initn: 4535 init1: 4535 opt: 4535 Z-score: 2071.2 bits: 393.7 E(85289): 1.3e-108
Smith-Waterman score: 4535; 99.9% identity (99.9% similar) in 678 aa overlap (15-692:39-716)
10 20 30 40
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEE
: ::::::::::::::::::::::::::::
XP_011 SCSACVKGELRVLTSAALTSRDGPRPCHVLFRIVHLCLRKADQKLVIIKQIPVEQMTKEE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 NTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQK
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 AGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 CLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTEREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTEREL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 FAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRF
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 NKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYT
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 FGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGR
610 620 630 640 650 660
650 660 670 680 690
pF1KE3 LGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
670 680 690 700 710
>>XP_016879989 (OMIM: 609799,613824,615415) PREDICTED: s (666 aa)
initn: 2833 init1: 2833 opt: 2833 Z-score: 1305.7 bits: 252.0 E(85289): 5.5e-66
Smith-Waterman score: 4346; 98.0% identity (98.0% similar) in 666 aa overlap (40-692:1-666)
10 20 30 40 50 60
pF1KE3 VGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYEN
::::::::::::::::::::::::::::::
XP_016 MTKEERQAAQNECQVLKLLNHPNVIEYYEN
10 20 30
70 80 90 100 110 120
pF1KE3 FLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 KTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWAL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 GCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPL
160 170 180 190 200 210
250 260 270 280 290
pF1KE3 SHIMAQPLCIRALLNLHTDVGSVRMRR-------------AEKSVAPSNTGSRTTSVRCR
::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 SHIMAQPLCIRALLNLHTDVGSVRMRRPVQGQRAVLGGRVAEKSVAPSNTGSRTTSVRCR
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE3 GIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILW
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE3 EAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFG
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE3 SGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLG
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE3 LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGE
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE3 EPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTN
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE3 TRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPR
580 590 600 610 620 630
660 670 680 690
pF1KE3 PVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
::::::::::::::::::::::::::::::::::::
XP_016 PVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
640 650 660
>>XP_016879988 (OMIM: 609799,613824,615415) PREDICTED: s (705 aa)
initn: 2833 init1: 2833 opt: 2833 Z-score: 1305.5 bits: 252.0 E(85289): 5.6e-66
Smith-Waterman score: 4600; 98.2% identity (98.2% similar) in 705 aa overlap (1-692:1-705)
10 20 30 40 50 60
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 THLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLS
190 200 210 220 230 240
250 260 270 280
pF1KE3 LEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRR-------------AEKSVAPSNTG
:::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 LEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRPVQGQRAVLGGRVAEKSVAPSNTG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 SRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 TRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 DRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAW
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 GRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 GLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGS
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 NQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGR
610 620 630 640 650 660
650 660 670 680 690
pF1KE3 RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
670 680 690 700
>>XP_011522940 (OMIM: 609799,613824,615415) PREDICTED: s (729 aa)
initn: 2833 init1: 2833 opt: 2833 Z-score: 1305.4 bits: 252.1 E(85289): 5.7e-66
Smith-Waterman score: 4499; 98.0% identity (98.0% similar) in 691 aa overlap (15-692:39-729)
10 20 30 40
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEE
: ::::::::::::::::::::::::::::
XP_011 SCSACVKGELRVLTSAALTSRDGPRPCHVLFRIVHLCLRKADQKLVIIKQIPVEQMTKEE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
190 200 210 220 230 240
230 240 250 260 270
pF1KE3 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRR--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRPVQGQRAV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 -----AEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGRVAEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLN
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 TEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE3 ASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE3 VPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE3 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAE
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE3 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVP
670 680 690 700 710 720
pF1KE3 P
:
XP_011 P
>>XP_016879990 (OMIM: 609799,613824,615415) PREDICTED: s (484 aa)
initn: 1733 init1: 1706 opt: 1706 Z-score: 799.9 bits: 157.9 E(85289): 8.2e-38
Smith-Waterman score: 1706; 99.6% identity (99.6% similar) in 262 aa overlap (15-276:39-300)
10 20 30 40
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEE
: ::::::::::::::::::::::::::::
XP_016 SCSACVKGELRVLTSAALTSRDGPRPCHVLFRIVHLCLRKADQKLVIIKQIPVEQMTKEE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEET
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPIS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRAEKSVAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRPVQGQRAV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 NTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQK
XP_016 LGGRVWAPSGSTGGLRQRETWGKSSLPACRNVRRVFVLRPPSVLQGREVRGPQQHREQDH
310 320 330 340 350 360
>>NP_001316166 (OMIM: 609798,614262,617022,617025) serin (991 aa)
initn: 917 init1: 595 opt: 1026 Z-score: 491.2 bits: 101.8 E(85289): 1.3e-20
Smith-Waterman score: 1376; 36.3% identity (64.0% similar) in 722 aa overlap (4-687:52-741)
10 20 30
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIK
: :::.:::::: . : : :..::. :
NP_001 SGGCGDSSPGPSASQGPRAGGGAAEQEELHYIPIRVLGRGAFGEATLYRRTEDDSLVVWK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 QIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQ
.. . .....::. : :: .: ::.: :.: ::..:... .:.: .:: ::.: . :
NP_001 EVDLTRLSEKERRDALNEIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKIL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 KRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKI
.. ..:.::: .. .. ::. :. .: :::::.:: ::.: : .. :.::.:..:
NP_001 RQKDKLFEEEMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLI-KLGDYGLAKK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 LSSK-SKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALV
:.:. : : :.:::: :.:::::.: :: ::::::.:::..:: .:::.:.:.: :
NP_001 LNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLC
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 LKIMSGTFAPISD--RYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVG
.::..: : : .:: :: :.: : :. .: ::: .... .:: .:
NP_001 VKIVQGIRAMEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLDRPL-LRK---------
270 280 290 300 310
280 290 300 310 320 330
pF1KE3 SVRMRRAEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPML
: :. :..:. :. .. : . ..:. .. : ::.:::: .:: .: ..
NP_001 --RRREMEEKVTLLNAPTKRP--RSSTVTEAPI-AVVTSRTSEVYVWGGGKSTPQKLDVI
320 330 340 350 360
340 350 360 370 380
pF1KE3 NT--EVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQP------QPQFIS
.. . :: :: :. : :: .: : .. ::. : : . . ::. .
NP_001 KSGCSARQVCAGNTHFAVVTVEKELYTW----VNMQGGTKLHGQLGHGDKASYRQPKHVE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE3 RFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT--DISQPTIVEAL
. :.:.. :..:.::: ::.:.::.: ...::: ::.: ... .. .: .. .
NP_001 K-LQGKA---IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFF
430 440 450 460 470
450 460 470 480
pF1KE3 LGYEMVQVACGASHVLALSTERELFAWGRGD------------SGRLGLGTRESHSCPQQ
:. . ::.:: .::..:. ..:...:: :. .::::: ..:.. ::.
NP_001 LSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRGSLVSVHFFTGRLGLDSEEDYYTPQK
480 490 500 510 520 530
490 500 510 520 530 540
pF1KE3 VPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEA-
: .: . : :: :....:: :..:::: :.::::::.. : . :. .:.
NP_001 VDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSG--IINHEAYHEVP
540 550 560 570 580 590
550 560 570 580 590 600
pF1KE3 --LSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPC
:::: . :. . .: : .:.::. : ::: :. ::::... . .:
NP_001 YTTSFTL--AKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYK-KRLGI
600 610 620 630 640 650
610 620 630 640 650
pF1KE3 KVQG--LEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG----RRDEDAGL----P
.. : : : .. :.::: ::.: ......::.:. :::. .: . . . :
NP_001 NLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRLAMTPTERPHGSDICTSWP
660 670 680 690 700 710
660 670 680 690
pF1KE3 RPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP
::. . : : ..:: .:.: :..: .
NP_001 RPIFGSLHH---VPDLSCRGWHTILIVEKVLNSKTIRSNSSGLSIGTVFQSSSPGGGGGG
720 730 740 750 760
NP_001 GGGEEEDSQQESETPDPSGGFRGTMEADRGMEGLISPTEAMGNSNGASSSCPGWLRKELE
770 780 790 800 810 820
>>XP_005268266 (OMIM: 609798,614262,617022,617025) PREDI (873 aa)
initn: 729 init1: 407 opt: 837 Z-score: 406.6 bits: 86.0 E(85289): 6.6e-16
Smith-Waterman score: 1187; 35.4% identity (63.1% similar) in 655 aa overlap (71-687:1-623)
50 60 70 80 90 100
pF1KE3 TKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLL
... .:.: .:: ::.: . : .. ..:.
XP_005 MDNTTLLIELEYCNGGNLYDKILRQKDKLF
10 20 30
110 120 130 140 150
pF1KE3 EEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSK-SK
::: .. .. ::. :. .: :::::.:: ::.: : .. :.::.:..: :.:. :
XP_005 EEEMVVWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLI-KLGDYGLAKKLNSEYSM
40 50 60 70 80
160 170 180 190 200 210
pF1KE3 AYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGT
: :.:::: :.:::::.: :: ::::::.:::..:: .:::.:.:.: : .::..:
XP_005 AETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGI
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE3 FAPISD--RYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRRA
: : .:: :: :.: : :. .: ::: .... .:: .: : :.
XP_005 RAMEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLDRPL-LRK-----------RRREM
150 160 170 180 190
280 290 300 310 320 330
pF1KE3 EKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNT--EVV
:..:. :. .. : . ..:. .. : ::.:::: .:: .: .... .
XP_005 EEKVTLLNAPTKRP--RSSTVTEAPI-AVVTSRTSEVYVWGGGKSTPQKLDVIKSGCSAR
200 210 220 230 240 250
340 350 360 370 380
pF1KE3 QVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQP------QPQFISRFLEGQS
:: :: :. : :: .: : .. ::. : : . . ::. . . :.:..
XP_005 QVCAGNTHFAVVTVEKELYTW----VNMQGGTKLHGQLGHGDKASYRQPKHVEK-LQGKA
260 270 280 290 300
390 400 410 420 430 440
pF1KE3 GVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLT--DISQPTIVEALLGYEMVQ
:..:.::: ::.:.::.: ...::: ::.: ... .. .: .. .:. . :
XP_005 ---IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQ
310 320 330 340 350 360
450 460 470 480 490
pF1KE3 VACGASHVLALSTERELFAWGRGD------------SGRLGLGTRESHSCPQQVPMPPGQ
:.:: .::..:. ..:...:: :. .::::: ..:.. ::.: .: .
XP_005 VSCGDNHVVVLTRNKEVYSWGCGEYGRGSLVSVHFFTGRLGLDSEEDYYTPQKVDVPKAL
370 380 390 400 410 420
500 510 520 530 540 550
pF1KE3 EAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEA---LSFTL
: :: :....:: :..:::: :.::::::.. : . :. .:. ::::
XP_005 IIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSG--IINHEAYHEVPYTTSFTL
430 440 450 460 470 480
560 570 580 590 600 610
pF1KE3 LGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQG--L
. :. . .: : .:.::. : ::: :. ::::... . .: .. : :
XP_005 --AKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYK-KRLGINLLGGPL
490 500 510 520 530 540
620 630 640 650 660
pF1KE3 EGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG----RRDEDAGL----PRPVQLDE
: .. :.::: ::.: ......::.:. :::. .: . . . :::. .
XP_005 GGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRLAMTPTERPHGSDICTSWPRPIFGSL
550 560 570 580 590 600
670 680 690
pF1KE3 THPYTVTSVSCCHGNTLLAVRSVTDEPVPP
: : ..:: .:.: :..: .
XP_005 HH---VPDLSCRGWHTILIVEKVLNSKTIRSNSSGLSIGTVFQSSSPGGGGGGGGGEEED
610 620 630 640 650
>>XP_011533370 (OMIM: 616731) PREDICTED: serine/threonin (483 aa)
initn: 831 init1: 456 opt: 814 Z-score: 398.5 bits: 83.7 E(85289): 1.9e-15
Smith-Waterman score: 814; 46.5% identity (79.5% similar) in 258 aa overlap (1-257:73-330)
10 20 30
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLV
:.::. :...:.:::: ..: :.:.:
XP_011 LSVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHC
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE3 IIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAE
.::.: :.: .:..:...: .:. ..:::.. ....: :. :.:.::: :: : .
XP_011 VIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMK
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE3 FIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGI
:... . :. :. :: .:::: :.:.:.: . :::::.:.:::.:.:. ::.:.:::::
XP_011 RINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGI
170 180 190 200 210 220
160 170 180 190 200
pF1KE3 SKILSSKSK-AYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLP
...:... . : : .::: :.:::.:..::::.:.:::.:::::::: .::. ::. ::
XP_011 ARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQ
230 240 250 260 270 280
210 220 230 240 250 260
pF1KE3 ALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDV
::::: .. ::::: .: ::..:. .:... : .:: .. :. .:.
XP_011 QLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPE
290 300 310 320 330 340
270 280 290 300 310 320
pF1KE3 GSVRMRRAEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPM
XP_011 VIQEEFSHMLICRAGAPASRHAGKVVQKCKIQKVRFQGKCPPRSRISVPIKRNAILHRNE
350 360 370 380 390 400
>>XP_006719871 (OMIM: 616731) PREDICTED: serine/threonin (598 aa)
initn: 831 init1: 456 opt: 814 Z-score: 397.7 bits: 83.8 E(85289): 2.1e-15
Smith-Waterman score: 814; 46.5% identity (79.5% similar) in 258 aa overlap (1-257:73-330)
10 20 30
pF1KE3 MEKYERIRVVGRGAFGIVHLCLRKADQKLV
:.::. :...:.:::: ..: :.:.:
XP_006 LSVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHC
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE3 IIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAE
.::.: :.: .:..:...: .:. ..:::.. ....: :. :.:.::: :: : .
XP_006 VIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMK
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE3 FIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGI
:... . :. :. :: .:::: :.:.:.: . :::::.:.:::.:.:. ::.:.:::::
XP_006 RINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGI
170 180 190 200 210 220
160 170 180 190 200
pF1KE3 SKILSSKSK-AYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLP
...:... . : : .::: :.:::.:..::::.:.:::.:::::::: .::. ::. ::
XP_006 ARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQ
230 240 250 260 270 280
210 220 230 240 250 260
pF1KE3 ALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDV
::::: .. ::::: .: ::..:. .:... : .:: .. :. .:.
XP_006 QLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPE
290 300 310 320 330 340
270 280 290 300 310 320
pF1KE3 GSVRMRRAEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPM
XP_006 VIQEEFSHMLICRAGAPASRHAGKVVQKCKIQKVRFQGKCPPRSRISVPIKRNAILHRNE
350 360 370 380 390 400
692 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:21:17 2016 done: Mon Nov 7 18:21:19 2016
Total Scan time: 10.940 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]