Result of FASTA (omim) for
pFN21AE3253
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3253, 589 aa
1>>>pF1KE3253 589 - 589 aa - 589 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6595+/-0.000284; mu= 9.4318+/- 0.018
mean_var=145.3398+/-29.791, 0's: 0 Z-trim(123.0): 5 B-trim: 1634 in 2/54
Lambda= 0.106385
statistics sampled from 42099 (42104) to 42099 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.494), width: 16
Scan time: 10.250
The best scores are: opt bits E(85289)
NP_149016 (OMIM: 606458) cysteine/serine-rich nucl ( 589) 4065 635.2 1.8e-181
XP_016862537 (OMIM: 606458) PREDICTED: cysteine/se ( 589) 4065 635.2 1.8e-181
NP_001307489 (OMIM: 606458) cysteine/serine-rich n ( 589) 4065 635.2 1.8e-181
NP_001307488 (OMIM: 606458) cysteine/serine-rich n ( 609) 4065 635.2 1.8e-181
XP_016862538 (OMIM: 606458) PREDICTED: cysteine/se ( 329) 2276 360.5 5.1e-99
>>NP_149016 (OMIM: 606458) cysteine/serine-rich nuclear (589 aa)
initn: 4065 init1: 4065 opt: 4065 Z-score: 3379.0 bits: 635.2 E(85289): 1.8e-181
Smith-Waterman score: 4065; 99.8% identity (100.0% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KE3 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANLDASCFLNGGLEGSREGSLPG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_149 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
490 500 510 520 530 540
550 560 570 580
pF1KE3 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
550 560 570 580
>>XP_016862537 (OMIM: 606458) PREDICTED: cysteine/serine (589 aa)
initn: 4065 init1: 4065 opt: 4065 Z-score: 3379.0 bits: 635.2 E(85289): 1.8e-181
Smith-Waterman score: 4065; 99.8% identity (100.0% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KE3 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANLDASCFLNGGLEGSREGSLPG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
490 500 510 520 530 540
550 560 570 580
pF1KE3 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
550 560 570 580
>>NP_001307489 (OMIM: 606458) cysteine/serine-rich nucle (589 aa)
initn: 4065 init1: 4065 opt: 4065 Z-score: 3379.0 bits: 635.2 E(85289): 1.8e-181
Smith-Waterman score: 4065; 99.8% identity (100.0% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KE3 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANLDASCFLNGGLEGSREGSLPG
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
490 500 510 520 530 540
550 560 570 580
pF1KE3 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
550 560 570 580
>>NP_001307488 (OMIM: 606458) cysteine/serine-rich nucle (609 aa)
initn: 4065 init1: 4065 opt: 4065 Z-score: 3378.8 bits: 635.2 E(85289): 1.8e-181
Smith-Waterman score: 4065; 99.8% identity (100.0% similar) in 589 aa overlap (1-589:21-609)
10 20 30 40
pF1KE3 MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVS
::::::::::::::::::::::::::::::::::::::::
NP_001 MSETRLRLSVPRPQSTSGTTMTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RAWDSEEEGPWDQMPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAWDSEEEGPWDQMPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 TSVPSRGGCTLGMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSVPSRGGCTLGMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 VPQAEAGLPPVVDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQAEAGLPPVVDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRID
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 REEKRELQALRQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEKRELQALRQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMG
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 RVEFNQARVQTHFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEFNQARVQTHFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMN
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 NELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 DFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANL
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 DFGGEEEEEEEGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 DASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHY
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 TSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQKVSDSLDNIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVP
550 560 570 580 590 600
pF1KE3 ASLMEPVPV
:::::::::
NP_001 ASLMEPVPV
>>XP_016862538 (OMIM: 606458) PREDICTED: cysteine/serine (329 aa)
initn: 2276 init1: 2276 opt: 2276 Z-score: 1898.8 bits: 360.5 E(85289): 5.1e-99
Smith-Waterman score: 2276; 99.7% identity (100.0% similar) in 329 aa overlap (261-589:1-329)
240 250 260 270 280 290
pF1KE3 RQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQ
::::::::::::::::::::::::::::::
XP_016 MDHTAFPCGCCREGCENPMGRVEFNQARVQ
10 20 30
300 310 320 330 340 350
pF1KE3 THFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSS
40 50 60 70 80 90
360 370 380 390 400 410
pF1KE3 DMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEE
100 110 120 130 140 150
420 430 440 450 460 470
pF1KE3 EGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGILDENANLDASCFLNGGL
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_016 EGSVGNLDNLSCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGL
160 170 180 190 200 210
480 490 500 510 520 530
pF1KE3 EGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLD
220 230 240 250 260 270
540 550 560 570 580
pF1KE3 NIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV
280 290 300 310 320
589 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:52:52 2016 done: Mon Nov 7 16:52:53 2016
Total Scan time: 10.250 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]